Clinical trials: Cardiometabolic Factors
Cardiometabolic Syndrome, Type 2 Diabetes
Circadian Intervention to Improve Cardiometabolic Health
The overall goal is to examine the efficacy of a circadian intervention in people with overweight and obesity and habitual short sleep duration (HSSD).
- Conditions
- Cardiometabolic Syndrome, Type 2 Diabetes, Sleep, Time Restricted Feeding
- Trial name
- TOCS (NCT05943626)
- Testing
- Circadian Intervention
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Utah
Overweight and Obesity, Prediabetes
Effects of Biofunctional Orange Juice on Cardiometabolic Risk Markers
The effects of orange juice enriched with vitamin D3 and encapsulated probiotics (Lacticaseibacillus casei Shirota and Lacticaseibacillus rhamnosus GG) compared to conventional orange juice on several cardiometabolic and…
- Conditions
- Overweight and Obesity, Prediabetes, Hypertension, Dyslipidemias
- Trial name
- NCT06114576
- Testing
- Orange juice enriched with vitamin D3 and encapsulated probiotics, Conventional orange juice
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- Agricultural University of Athens
Obesity, Cardiovascular Risk Factor
Exercise for Preventing the Metabolic Syndrome in Latinoamerican Amerindians
Despite exercise training decrease blood fasting glicaemy in 'average' terms, there is a wide inter-individual variability after exercise training explored mainly in adults but not in adults with prediabetes comorbidities.
- Conditions
- Obesity, Cardiovascular Risk Factor, Physical Activity
- Trial name
- NCT03653468
- Testing
- Concurrent training (CT)
- Where
- Chile
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Universidad Santo Tomas
Spinal Cord Injuries, Exercise Training
Effect of Upper-body Rowing on Cardiometabolic Risk in Spinal Cord Injured Wheelchair Users
This randomized controlled trial will determine the effects of 12-weeks of wheelchair user-modified upper-body rowing on both traditional cardiometabolic risk factors in SCI manual wheelchair users.
- Trial name
- NCT04390087
- Testing
- Exercise
- Where
- Denmark
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Vitamin D Deficiency
Impact of Vitamin D Supplementation on Cardiometabolic Risk Factors [The Daily D Health Study]
The purpose of this research is to determine what supplemental doses of vitamin D may be necessary to raise serum levels to optimal levels and how vitamin D supplementation and changes in vitamin D status impact cardiovascular…
- Trial name
- NCT01537809
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 691 people, healthy volunteers welcome
- Sponsor
- Tufts University
Obesity, Cardiovascular Disease
Role of Cardiometabolic Risk Factors in Childhood Bone Development
The proposed research brings together complementary expertise to systematically elucidate the longitudinal effects of (1) total and regional body fat and (2) the metabolic impairment that accompanies obesity on bone development…
- Conditions
- Obesity, Cardiovascular Disease, Type 2 Diabetes, Osteoporosis
- Trial name
- NCT02355717
- Testing
- Observational Study
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Augusta University
Diet Modification, Cardiovascular Risk Factor
Bioavailability and Beneficial Properties of Coffee and Cocoa Bioactive Compounds
The aim of this study will be to define the bioavailability and the beneficial properties of coffee bioactive compounds. Moreover, the contribution of cocoa-based products containing coffee to the pool of circulating metabolites…
- Conditions
- Diet Modification, Cardiovascular Risk Factor, Nutritional and Metabolic Diseases
- Trial name
- P4L (NCT03166540)
- Testing
- cup of espresso coffee, cocoa-based products containing coffee
- Where
- Italy
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Parma
Bipolar Youth Treated With Second-generation Antipsychotics
SGA-induced Metabolic Syndrome in Bipolar Youth
The investigators tested the hypothesis that long-chain omega-3 (LCn-3) fatty acid supplementation will attenuate the adverse cardiometabolic effects of second-generation antipsychotics exposure in first-episode adolescent manic…
- Trial name
- NCT01858948
- Testing
- Omega, Quetiapine fumarate
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Cincinnati
Diabetes Mellitus
The Effect of Cinnamon Cassia on Diabetes Control and Cardiometabolic Risk Factors in Adults With Type 2 Diabetes Mellitus
The overall goal of this proposal is to establish the efficacy of cinnamon for the treatment of T2DM. Additional aims will assess the effect of cinnamon on cardiovascular risk factors and explore novel potential mechanisms of…
- Trial name
- NCT02942056
- Testing
- Cinnamon
- Sponsor
- Oregon Health and Science University
Dyslipidemia, Diabetes
Meta-analyses of Fructose and Cardiometabolic Risk
Diabetes and heart associations continue to discourage high intakes of dietary fructose, a constituent part of the sucrose molecule that is found in fruits and vegetables as a natural sugar and in some processed foods and…
- Conditions
- Dyslipidemia, Diabetes, Prediabetes, Dysglycemia
- Trial name
- NCT01363791
- Testing
- Dietary fructose
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- John Sievenpiper
Cardiometabolic Diseases
Sustainable Diets and Cardiometabolic Health
This study aims to investigate the effects of sustainable diets on traditional and novel cardiometabolic risk factors. The primary objective is: To test the effects of a sustainable diet on traditional cardiometabolic risk…
- Trial name
- PlanetDiet (NCT07189676)
- Testing
- Dietary advice (PHD), Dietary advice (Ovo-lacto-vegetarian diet), Dietary advice (control)
- Where
- Denmark
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Cardiometabolic Health
Effect of Differently Fed Farmed Gilthead Sea Bream Consumption
The trial was a double-blind randomized dietary intervention study with a 1:1 allocation ratio, conducted in accordance with the Declaration of Helsinki.
- Trial name
- NCT05417191
- Testing
- Conventional fish, Enriched fish
- Where
- Greece
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Cardiac Abnormalities
Alleviation of Cardiometabolic Risk Factors Through Watermelon Rind
To collect data, written consent was obtained from the hospital and university administration. After receiving signed informed consent, the data was collected from cardiac patients.
- Trial name
- NCT07609524
- Testing
- Control on Wheat bread, Experimental G1 on WRB, Experimental G2 on WRB
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- University of Lahore
Bariatric Patients
Quality of Life and Cardiometabolic Risk Factors in Patients After Debanding
Follow up of debanding patients
- Trial name
- NCT00497627
- Where
- Switzerland
- Volunteers
- 12 people
- Sponsor
- University of Zurich
Endocrine Disruptors, Inflammation
The Plastic Exposure Reduction Transforms Health Trial
The goal of this randomized controlled trial is to learn if an intervention of reducing plastic exposure through diet, personal care and cleaning products can improve health outcomes in adult participants with cardiometabolic…
- Conditions
- Endocrine Disruptors, Inflammation, Cardiometabolic Risk Factors
- Trial name
- PERTH (NCT06571994)
- Testing
- Low Plastic Intervention
- Where
- Australia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Western Australia
Cardiometabolic Risk Factors
Effect of Vitamin D on Cardiovascular Metabolic Risk in Overweight/Obesity Adolescents in China
The goal of this randomized controlled clinical trial is to investigate the effects of vitamin D3 supplementation on cardiometabolic risk in Chinese adolescents with overweight/obesity and vitamin D deficiency.
- Trial name
- NCT07053657
- Testing
- Dietary Supplement: Vitamin D3
- Where
- 2 sites in China
- Volunteers
- 130 people
- Sponsor
- Anhui Medical University
Obesity
Modified Intermittent Eating on Weight Loss (INTEREST-3 Trial)
Calorie restriction (CR) is the most important treatment for weighting loss. In recent years, two novel types of intermittent fasting recently have gained more attention: the 5:2 diet and time-restricted eating (TRE).
- Trial name
- INTEREST-3 (NCT06302803)
- Testing
- Intermittent fasting plus time-restricted eating, Calorie restriction
- Where
- China
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
ASCVD, Hyperlipidemia
Duke Cardiometabolic Prevention Clinic's Impact on High-risk Cardiovascular Patients With Uncontrolled Risk Factors
This project is studying whether a team-based specialty clinic can help people with type 2 diabetes and heart disease better manage their blood pressure and cholesterol.
- Conditions
- ASCVD, Hyperlipidemia, Hypertension
- Trial name
- DUKE PREVENT (NCT07117695)
- Testing
- Referral to the Duke Cardiometabolic Prevention Clinic
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Duke University
Exercise, Cerebral Palsy
RaceRunning for Young People With Moderate-to-severe Cerebral Palsy
Physical inactivity in people with cerebral palsy (CP) has been linked with increased risk of cardiometabolic disease. Exercise studies rarely include people with CP with severe walking impairments and assess the sustainability…
- Trial name
- NCT04034342
- Testing
- RaceRunning
- Where
- 2 sites in United Kingdom
- Volunteers
- 25 people
- Sponsor
- Queen Margaret University
Type 2 Diabetes
Effects of Exercise on sRAGE Levels and Cardiometabolic Risk Factors
The purpose of this study is to examine the effects of exercise on diverse cardiometabolic risk factors and indicators of atherosclerosis in patients with type 2 diabetes mellitus (T2DM).
- Trial name
- NCT01542775
- Testing
- Aerobic Exercise Group, Control Group
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Korea University