Clinical trials: Cardiometabolic Factors
Vitamin D Deficiency
Impact of Vitamin D Supplementation on Cardiometabolic Risk Factors [The Daily D Health Study]
The purpose of this research is to determine what supplemental doses of vitamin D may be necessary to raise serum levels to optimal levels and how vitamin D supplementation and changes in vitamin D status impact cardiovascular…
- Trial name
- NCT01537809
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 691 people, healthy volunteers welcome
- Sponsor
- Tufts University
Cardiometabolic Risk Factors
SPICE UP MyPlate - Strategy for Promoting Intake of Delicious Healthful Dietary Patterns Based on MyPlate: A Pilot Study
The aim is to conduct a pilot study to assess the feasibility, acceptability and potential effectiveness of culinary focused nutrition education to promote increased adherence to the Dietary Guidelines for Americans compared to…
- Trial name
- NCT06890728
- Testing
- Culinary focused nutrition education, Standard low intensity nutrition education
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Penn State University
Cardiometabolic Risk Factors in Adult Wheelchair Users
Cardiometabolic Health Intervention Using Movement-to-Music Exercise
The study aims to test the benefits of a 24-week, cardio-emphasized Movement-to-Music exercise program for reversing cardiometabolic health risk factors compared to asynchronous, standard exercise programs among 132 adult…
- Trial name
- CHIME (NCT05606432)
- Testing
- Instructor-led, one-on-one M2M exercise group, Self-guided control with pre-recorded standard exercise videos
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- University of Alabama at Birmingham
Diabetes Mellitus, Type 2, Diet, Vegetarian
The Effect of an Online Plant-Based Dietary Program on Cardiovascular Risk Factors in Persons With Type 2 Diabetes Mellitus: A Randomized Controlled Trial
Persons with Type 2 Diabetes (T2D) are at an increased risk of cardiovascular disease (CVD) and mortality. Dietary changes are recommended by guidelines to treat T2D and reduce risk of CVD.
- Conditions
- Diabetes Mellitus, Type 2, Diet, Vegetarian, Diet, Vegan, Cardiometabolic Risk Factors
- Trial name
- Plate-DM (NCT05777746)
- Testing
- 12-week plant-based dietary program, Usual Diet
- Where
- Netherlands
- Volunteers
- 140 people
- Sponsor
- UMC Utrecht
Risk Factors Cardiovascular Disease
Cardiorespiratory Prevention and Rehabilitation Program (PROCOR): Assessment and Prescription of Exercises for People With Cardiometabolic Diseases.
The global aging of the population presents significant challenges to health and quality of life, especially among the elderly, who face a higher prevalence of cardiometabolic risk factors.
- Trial name
- NCT07529158
- Testing
- PROCOR 2024.1
- Where
- Brazil
- Volunteers
- 22 people
- Sponsor
- Universidade Federal de Santa Catarina
Cardiovascular Diseases, Metabolic Syndrome
Diets, Lipoproteins and Inflammation Markers
Systematic inflammation and lipid profiles are two major therapeutic targets for cardiovascular diseases. The effectiveness of vegan diet has been reported (doi: 10.3389/fnut.2022.807810).
- Conditions
- Cardiovascular Diseases, Metabolic Syndrome, Diet, Healthy, Vegan Diet
- Trial name
- NCT05423457
- Testing
- Vegan diet
- Where
- Taiwan
- Volunteers
- 21 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Obesity, Microalbuminuria
Evaluation of the Rimonabant Impact on the Regression of Asymptomatic Damage Caused by Cardiovascular Risk Factors
Primary objective: To assess the effect on microalbuminuria levels of treatment with rimonabant 20 mg versus a placebo during a 12 month period.
- Conditions
- Obesity, Microalbuminuria, Diabetes Mellitus, Type 2, Dyslipidemia
- Trial name
- RIALTO (NCT00458081)
- Testing
- Rimonabant
- Where
- Spain
- Volunteers
- 174 people
- Sponsor
- Sanofi
Cardiovascular Risk Factor, Heart Diseases
Effect of Macadamia Nut on Cardiometabolic Risk Factors
This research study will test the effects of macadamia nuts on adiposity, and traditional and emergent risk factors of cardiometabolic disease in adult men and women
- Conditions
- Cardiovascular Risk Factor, Heart Diseases, Inflammation
- Trial name
- MAC (NCT03801837)
- Testing
- Macadamia Nut, Control Diet
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Overweight, Obesity
Meta-analyses of Total and Individual Fructose-containing Sugars and Incident Cardiometabolic Disease
Since uncontrolled observational studies first linked fructose to the epidemic of obesity almost a decade ago, it has become a focus of intense concern regarding its role in the obesity epidemic and increasing burden of…
- Conditions
- Overweight, Obesity, Dyslipidemia, Hyperlipidemia
- Trial name
- NCT01608620
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- John Sievenpiper
Cardiometabolic Risk Factors
Metabolic Wellness and CGM
The primary objective of this study is to determine the impact of participating in an online lifestyle intervention program on glycemic control as measured by Continuous Glucose Monitoring (CGM), with the primary outcome being…
- Trial name
- NCT06790472
- Testing
- Online Lifestyle Intervention, Continuous Glucose Monitoring
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- David Kerr
Hypertension
Effects of the DASH vs. the Mediterranean Diet Combined With Salt Restriction on Blood Pressure Levels in Adults
Non-pharmacological measures should serve as the first-line treatment in individuals with high normal blood pressure (BP) levels or grade 1 hypertension and low-moderate cardiovascular disease risk.
- Trial name
- NCT05669404
- Testing
- Salt Restriction Group (SRG), DASH Diet combined with salt restriction Group (DDG), Mediterranean Diet combined with salt restriction Group (MDG)
- Where
- Greece
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Hippocration General Hospital
Metabolic Disease, Cardiovascular Disease
The Psoriasis, Atherosclerosis, and Cardiometabolic Disease Initiative (PACI)
Background: Cardiometabolic diseases are medical disorders that can occur together and affect the heart. They increase the risk of developing heart disease and diabetes.
- Conditions
- Metabolic Disease, Cardiovascular Disease, Inflammation, Psoriasis
- Trial name
- NCT01778569
- Where
- United States
- Volunteers
- 386 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Physical Activity, Cardiometabolic Risk Factors
Going Places: A Multi-level Intervention to Improve Youth Transportation Efficacy and Physical Activity
Going Places is a community driven intervention to increase transportation self-efficacy among low-income youth, enabling access to community-based programs that promote physical activity and improve long term cardiometabolic…
- Conditions
- Physical Activity, Cardiometabolic Risk Factors, Cardiometabolic Health Indicators, Self-Efficacy
- Trial name
- Going Places (NCT07044375)
- Testing
- Going Places
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- Duke University
Obesity, Dyslipidemia
Reduction of Sweetened Beverages and Intrahepatic Fat
The study will enroll 68 overweight male and female subjects with a high (> 2 3dl-can soda/day) consumption of sweetened beverage per day.
- Conditions
- Obesity, Dyslipidemia, Metabolic Syndrome
- Trial name
- REDUCS (NCT01394380)
- Testing
- artificially sweetened sodas
- Where
- Switzerland
- Volunteers
- 29 people
- Sponsor
- University of Lausanne
Hypertension, Cardiovascular Disease
Meta-analyses of the Effect of Legumes on Blood Pressure
Legumes are generally recognized as healthy dietary components, and although beans and legumes are recommended in food guidelines in North America, guidelines vary in regards to how much and how often these foods should be…
- Conditions
- Hypertension, Cardiovascular Disease, Dyslipidemia, Diabetes
- Trial name
- NCT02600338
- Testing
- Legumes
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- John Sievenpiper
Obesity
Effect of Oral Supplementation With Probiotics
Effect of oral supplementation with probiotics on cardiometabolic risk factors, microflora and intestinal epithelial permeability, mineral content and lifestyle in obese women with postmenopausal metabolic syndrome: double-blind…
- Trial name
- NCT03100162
- Testing
- Probiotic
- Where
- Poland
- Volunteers
- 81 people
- Sponsor
- Poznan University of Medical Sciences
Autism Spectrum Disorder (ASD), Cardiometabolic Health Indicators
This Study Will Evaluate Cardiorespiratory and Muscular Fitness to Examine Associations With Anthropometric Characteristics and Other Indicators of Cardiometabolic Risk Among Patients With or Without Autism Spectrum Disorder
The goal of this observational study is to evaluate cardiorespiratory and muscular fitness in children with obesity, with and without autism spectrum disorder (ASD), and examine how fitness relates to body measurements, body…
- Conditions
- Autism Spectrum Disorder (ASD), Cardiometabolic Health Indicators, Cardiometabolic Risk Factors, Metabolic Syndrome
- Trial name
- ROACH (NCT07804680)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Virginia
Lifestyle, Healthy, Muscle Weakness
RE-inventing Strategies for Healthy Ageing; Recommendations and Tools
The goal of the RESTART RCT is to examine whether a complex lifestyle intervention, coordinated with municipal and non-government organizations (NGO), can establish and preserve improvements in risk factors and functional…
- Conditions
- Lifestyle, Healthy, Muscle Weakness, Abdominal Obesity, Cardiometabolic Syndrome
- Trial name
- RESTART (NCT06122441)
- Testing
- Complex lifestyle intervention, Physical activity monitoring and recommendations
- Where
- Norway
- Volunteers
- 119 people
- Sponsor
- University of Tromso
Cardiovascular Diseases, Metabolic Syndrome
Effect of Dried Fruit on Cardiometabolic Risk Factors
This is a 2-period randomized crossover study with free-living subjects on self-selected diets. The objective of this study is to compare the effects of ¾ cup of a blend of dried plums, figs, dates and raisins (DPFDR) with an…
- Trial name
- NCT03020758
- Testing
- Dried Fruit, High Carbohydrate Snack
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Penn State University
Metabolic Syndrome
Effect of Orange Juice and Healthy Diet on Cardiometabolic Risk Factors of Individuals With Metabolic Syndrome
This study aimed to verify if combination of a healthy diet and orange juice consumption can minimize cardiometabolic risk factors for Metabolic Syndrome (MetS)
- Trial name
- NCT03301675
- Testing
- Orange Juice (500 mL/d)
- Volunteers
- 76 people
- Sponsor
- São Paulo State University