Clinical trials: Cardiometabolic Health
Cardiovascular Diseases
Diet Quality, Pecans, and Cardiometabolic Health
A three-period, randomized, crossover controlled feeding trial will be conducted to examine the effect of including 2 oz./day of pecans, as a snack, in a diet representative of average American intake, compared to a diet…
- Trial name
- NCT04487808
- Testing
- Pecan, Average American Diet devoid of nuts
- Volunteers
- healthy volunteers welcome
- Sponsor
- Penn State University
Obesity
The Effect of Methylsulfonylmethane (MSM) on Cardiometabolic Health
Obesity- related diseases are linked to elevated levels of inflammation, oxidative stress, and metabolic dysfunction. Methylsulfonylmethane (MSM) is a naturally occurring compound that demonstrates antioxidant and…
- Trial name
- NCT03716791
- Testing
- methylsulfonylmethane
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Lindsey Miller
Intervention Study, Health Behavior
Effects of an mHealth Intervention to Improve Health Behaviors Among Sedentary Workers
Background: Studies have shown the negative impact of physical inactivity, sedentary and unhealthy eating behavior on worker health and productivity.
- Trial name
- NCT04347096
- Testing
- mHealth Intervention, Control Intervention
- Where
- Taiwan
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Vegan Diet, Body Composition
Acute Metabolic Response Versus Long-term Adaptation to a Vegan Diet
At baseline, venous blood samples were collected from all eligible participants. The following biochemical parameters were analysed: serum electrolytes (mineral profile), fasting glucose, creatinine, urea nitrogen, total…
- Conditions
- Vegan Diet, Body Composition, Quality of Life (QOL), Cardiometabolic Health
- Trial name
- VITAL (NCT07731633)
- Testing
- vegan diet
- Where
- Slovakia
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University Hospital, Martin
Obesity and Overweight
Intermittent Carbohydrate Restriction in Cardiometabolic Health
Metabolic conditions, such as heart disease, type 2 diabetes, and metabolic syndrome, are among the leading causes of disability and mortality worldwide.
- Trial name
- NCT06684834
- Testing
- 5:2 carbohydrate restriction, Early time-restricted carbohydrate intake
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Bath
Metabolic Syndrome X
Efficacy Study Regarding the Beneficial Effects of Omega-3 Fatty Acids on Cardiometabolic Health
Fish oil supplements (which are rich in omega-3 fatty acids) have been shown to provide cardiometabolic benefits to individuals of all ages.
- Trial name
- FOHS (NCT02042274)
- Testing
- Fish oil supplement
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Guelph
Cardiovascular Diseases
The Cooking for Health Optimization and Disease Prevention (CHOP) Trial
Poor nutrition-related diseases disproportionately impact seniors and racial/ethnic minorities who are more likely to experience disparities in proper nutrition.
- Trial name
- NCT07011459
- Testing
- Cooking class, Standard of care
- Where
- 2 sites in United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Tulane University
Heart Diseases, Type2 Diabetes
Psychosocial, Environmental, and Chronic Disease Trends in Puerto Rico
The overall goal is to identify trends and longitudinal associations in psychosocial, food-related, and cardiometabolic risk factors that can guide public health priorities and future research needs aimed at reducing…
- Conditions
- Heart Diseases, Type2 Diabetes, Hypertension, Obesity
- Trial name
- PROSPECT (NCT03794531)
- Where
- Puerto Rico
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Cardiovascular Disease
the Canadian Health Improvement Network to Upgrade Prevention Services
RATIONALE Controlling cardiovascular risk factors has been proven to be effective in prevention and management of cardiovascular disease (CVD).
- Trial name
- CHIN-UPS (NCT02310685)
- Testing
- Comprehensive e-health wellness program
- Volunteers
- 459 people, healthy volunteers welcome
- Sponsor
- McGill University
Infant Malnutrition, Malnutrition in Pregnancy
Supplementing Maternal and Infant Diet With High-energy, Micronutrient Fortified Lipid-based Nutrient Supplements (LNS)
The use of lipid-based nutrients (LNS), such as Nutributter or fortified spread (FS), have been associated with improved growth and development outcomes among infants in Ghana and Malawi.
- Trial name
- iLiNS-DYAD-M (NCT01239693)
- Testing
- IFA, MMN, LNS
- Where
- Malawi
- Volunteers
- 1,391 people, healthy volunteers welcome
- Sponsor
- Tampere University
Endometrial Cancer
ImpRoving hEalth behaviourS for LIfe After ENdometrial CancEr Trial
RESILIENCE is 24-week randomized controlled trial that assesses the efficacy of a digital wellness platform, combined with online support from healthcare professionals, to enhance waist circumference and other vital health…
- Trial name
- RESILIENCE (NCT06038032)
- Testing
- Digital wellness platform, Online healthcare professional support
- Where
- 2 sites in Canada
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Polycystic Ovary Syndrome, Exercise
The Effects of High-intensity and Moderate-intensity Exercise on Polycystic Ovary Syndrome
This study will investigate the impact of high- and moderate-intensity exercise on the cardiometabolic and brain health of women with Polycystic Ovary syndrome (PCOS).
- Conditions
- Polycystic Ovary Syndrome, Exercise, Cerebrovascular Circulation
- Trial name
- NCT05394935
- Testing
- High-Intensity Exercise, Moderate-Intensity Exercise
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cardiff Metropolitan University
Aging, Sarcopenia
Resistance Exercise and Low-Intensity Physical Activity Breaks in Sedentary Time to Improve Muscle and Cardiometabolic Health
What are the effects of resistance exercise (RE) alone or RE plus low intensity physical activity (LPA) breaks in sedentary time (ST) on skeletal muscle health in older adults? What are the effects of resistance exercise (RE)…
- Conditions
- Aging, Sarcopenia, Disability Physical, Cardiovascular Diseases
- Trial name
- REALPA (NCT03771417)
- Testing
- Exercise Intervention
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Louisiana State University and A&M College
Cardiometabolic Health, Cognitive Function
The Effect of Oily Fish and Poultry on Children's Cardiometabolic Health and Cognitive Function
The purpose of FiSK Junior is to investigate whether intake of oily fish compared to poultry affects cardiovascular risk markers, cognitive function, and behaviour in healthy children.
- Trial name
- FiSK Junior (NCT02809508)
- Testing
- Oily fish, Poultry
- Where
- Denmark
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Insulin Resistance
Impact of Starch Digestibility on Glycemic Variability and Control, Cardiometabolic and Inflammatory Profiles, Microbiota and Intestinal Health in Subjects With Insulin Resistance
To study the potential impact of a diet rich in both Slowly Digestible Starch (SDS) and Resistant Starch (RS), we propose a 2-month nutritional intervention study in which we will study the evolution of carbohydrate variability…
- Trial name
- GLYMICARE (NCT07408479)
- Testing
- Balanced diet high in Slowly Digestible Starch and Resistant Starch, Balanced diet low in Slowly Digestible Starch and Resistant Starch
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mondelēz International, Inc.
Time Restricted Feeding, Exercise
Time-Restricted Eating, Exercise and Cardiometabolic Health in Obesity
In Spain, overweight and obesity prevalence is reaching 70% in men and 50% in women. Excess of triglycerides are usually stored in the subcutaneous adipose tissue (SAT), until a point where SAT is unable to expand further.
- Conditions
- Time Restricted Feeding, Exercise, Hepatic Steatosis, Cardiometabolic Syndrome
- Trial name
- TEMPUS (NCT05897073)
- Testing
- Time-restricted eating intervention, Exercise intervention, Time-restricted eating plus exercise intervention
- Where
- 2 sites in Spain
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Physical Inactivity
Effects of Physical Exercise Timing On Strength and Cardiometabolic Health
Physical exercise is well known to improve human health. Current guidelines provide recommendations on the frequency, intensity, type and duration of exercise.
- Trial name
- EPOCH (NCT06063135)
- Testing
- Physical Exercise Intervention
- Where
- Switzerland
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of Basel
Substance Use
Health and Resilience Projects: Foundations
The Health and Resilience Project (HARP): Foundations is investigating the efficacy of the Strong African American Families (SAAF) intervention in promoting the health and well being of African American adolescents.
- Trial name
- HARP-F (NCT05253235)
- Testing
- SAAF, Receipt of parenting book
- Where
- United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Cardiometabolic Health Indicators, Child Health
Non-Invasive Assessment of Early Health Determinants in Children and Adolescents
LONGEVITY-NEXT is a single-center, non-profit observational study designed to assess early non-invasive determinants of cardiometabolic, functional, behavioral, and environmental health in children and adolescents aged 6 to 17…
- Trial name
- LONGEVITY-NEXT (NCT07861516)
- Where
- Italy
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Cardiac Disease, Metabolic Disease
Cardiometabolic Disease Risk Factors in Cameroon
Cardiometabolic diseases (CMDs) are a major public health concern in sub-Saharan Africa, including Cameroon. Studies have shown a significant increase in the prevalence of hypertension, diabetes, and obesity in recent years.
- Trial name
- URBACAM-D (NCT06957548)
- Testing
- Cardiometabolic disease
- Where
- Cameroon
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University