Clinical trials: Cardiometabolic Risk
Cardiovascular Diseases
Effects of Breaking up Sitting Time on Cardiometabolic Risk Markers and Cardiac Function Post Myocardial Infarction
Cardiovascular Disease (CVD) is one of the greatest causes of mortality and morbidity globally, particularly in middle to high income countries. In the UK alone, it was accountable for 124,641 deaths in 2017.
- Trial name
- MOVE-MI (NCT05193175)
- Testing
- Prolonged sitting
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- University of Bedfordshire
Diabetes Mellitus, Type 2, Liver Fibrosis
Effect of an Early Time Restricted Eating Mediterranean Diet Compared to Naltrexone/Bupropion on Liver Fibrosis in People With Cardiometabolic Risk Factors in a Hospital Outpatient Clinic (MEDFAST-study)
In the Netherlands, there are many people with cardiometabolic diseases. More than half of these people also have fatty liver. This is a build-up of fat in the liver (steatosis) and can lead to long-term scarring (fibrosis) and…
- Conditions
- Diabetes Mellitus, Type 2, Liver Fibrosis, Liver Steatoses, Hepatic Steatosis
- Trial name
- MEDFAST (NCT06845345)
- Testing
- early time restricted Mediterranean diet, Mysimba
- Where
- Netherlands
- Volunteers
- 70 people
- Sponsor
- Carmen Dietvorst
Overweight and Obesity
Circadian Timing, Information Processing and Energy Balance Study
This study design will test biological and behavioral mechanisms in the cross-sectional analyses and determine the prospective effects of circadian alignment and sleep on changes in cardiometabolic risk factors.
- Trial name
- TIME (NCT04759755)
- Where
- United States
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- University of Utah
Obesity & Overweight, Cardiometabolic Risk Factors
Pilot Test of Five Weight Neutral Interventions to Improve Health Among Adults of Higher Body Weight
The purpose of this research study is to pilot test five different, group based and remotely delivered programs designed to support healthy eating and regular physical activity.
- Trial name
- NEW PATH (NCT07363616)
- Testing
- Mediterranean eating style, Physical activity, Mindful Eating
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Obesity
Effects of Exercise Training in Individuals Undergoing Bariatric Surgery
The subject of the research; Effects of exercise training on cardiometabolic risk factors and functional capacity in individuals undergoing bariatric surgery.
- Trial name
- NCT05085015
- Testing
- Functional Exercise Training Group, Home Exercise Training Group
- Where
- Cyprus
- Volunteers
- 64 people
- Sponsor
- Eastern Mediterranean University
Cardiovascular Risk Factor, Cholesterol; Lipidosis
Meta-analysis of the Portfolio Dietary Pattern and Cardiometabolic Risk
The European Association for the Study of Diabetes (EASD) guidelines have not made any specific recommendations regarding the Portfolio diet, a dietary pattern that includes nuts, viscous fibre, plant protein, and plant sterols.
- Trial name
- NCT03534414
- Testing
- Portfolio Dietary Pattern, NCEP Based Diet
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- University of Toronto
Metabolic Syndrome, Predisposition to Cardiovascular Disease
Analysis of the Postprandial Effects of a Vegetable Protein Mixture Rich in Arginine, Cysteine and Leucine on Endothelial Dysfunction and Inflammation at Low Noise in Elderly People With Cardiometabolic Risk
By 2050, the expanding world population will consume two-thirds more animal protein than it consumes today. The increase in chronic diseases associated with the generalization of these consumption patterns tend to understand the…
- Trial name
- P-PROBS CM (NCT04923555)
- Testing
- Vegetable proteins (VP) rich in leucine, cystein, arginine, Animal proteins (AP), No protein (T)
- Where
- France
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Spinal Cord Injuries
FES Cycling and Nutritional Counseling for Battling Obesity After SCI
Individuals who suffer from paralysis after spinal cord injury (SCI) are estimated to have an even greater (66%) prevalence of obesity.
- Trial name
- NCT03810963
- Testing
- HIIT-FES Cycling combined with Nutritional Counseling, Nutritional Counseling Only
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- William Carey University
Metabolic Disorders and Cognitive Decline
Effects of Whole Grain Rye on Metabolic Risk Markers and Mood
The purpose of the study is to investigate, in healthy middle age subjects, effects of whole grain rye on cognitive functions, mood, and cardiovasculair risk markers
- Trial name
- NCT03275948
- Testing
- whole grain, reference
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Lund University
Coaching, Cardiovascular Diseases
Health Coaching Programme on Health Promoting Behaviours in Middle-Aged Adults With Cardiometabolic Risk
Cardiometabolic disease has been an increasing trend globally and remains the major cause of morbidity and mortality in Hong Kong.
- Conditions
- Coaching, Cardiovascular Diseases, Metabolic Diseases
- Trial name
- NCT05284162
- Testing
- Health coaching
- Where
- Hong Kong
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Time Restricted Eating, Eating Behavior
Time Restricted Eating, Eating Behaviors, and Cardiometabolic Risk in Emerging Adult Women
The purpose of this study is to assess how time restricted eating interventions impact eating behaviors, diet quality, and body composition in women ages 20-29 years.
- Conditions
- Time Restricted Eating, Eating Behavior, Diet, Healthy, Nutrition, Healthy
- Trial name
- NCT06145009
- Testing
- Time restricted eating
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Obesity, Dietary Intervention
Effects of Boron and Mediterranean Diets on Gut Microbiota and Metabolic Health
This study investigated the effects of a boron-rich diet compared with a Mediterranean-style diet (Smart Alternative Food Formulation; SAFF) on obesity-related outcomes in adults.
- Conditions
- Obesity, Dietary Intervention, Gut Microbiota, Cardiometabolic Risk Factors
- Trial name
- BOR-SAFF (NCT07156097)
- Testing
- Mediterranean-style Diet (SAFF), Boron-rich Diet
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Dicle University
Sedentary, Cardiometabolic Syndrome
Effect of Interrupting Sedentary Time With Different Frequencies of Physical Activity on Cardiometabolic Risk Factors
The knowledge gap on sedentary behavior and sedentary breaks includes whether detrimental effects of sedentary behavior can be fully attenuated by 1.) sedentary breaks 2.) physical activity or 3.) both combined.
- Conditions
- Sedentary, Cardiometabolic Syndrome, Physical Activity
- Trial name
- NCT05622006
- Testing
- Sedentary breaks
- Where
- Norway
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Norwegian School of Sport Sciences
Cardiometabolic Risk Factors
Heart Focused Movement Effects on Cardiometabolic Risk
This study is designed as a two-group parallel randomized controlled trial (N=50) to test effects of 8-weeks of Qigong/Tai Chi (QTC) intervention compared to QTC plus HRVB on HRV parameters (primary), and cardiometabolic risk…
- Trial name
- NCT05687240
- Testing
- Qigong/Tai Chi, Heart rate variability biofeedback
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Cardiometabolic Risk, Abdominal Obesity
Characterization of Gut Microbiota Composition and Activity After a Daily Supplementation of 4.5 g/Day of ChitinGlucan Fibre During 3 Weeks in At-cardiometabolic Risk Volunteers
The aim of this study is to demonstrate the beneficial effects on gut microbiota composition and activity of the diary intake of insoluble fiber (extract from Aspergillus Niger) for three weeks.
- Trial name
- FITACHITIN (NCT03773900)
- Testing
- Kiotransine (chitin-glucan from aspergillus niger)
- Where
- France
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Overweight, Obesity
Network Meta-analyses of Artificially Sweetened Beverages and Cardiometabolic Risk
Sugars especially in form or sugar-sweetened beverages (SSBs) have been singled out as one of the prime culprits in the dual epidemics of obesity and diabetes.
- Trial name
- NCT02879500
- Testing
- Diet beverages
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- John Sievenpiper
Cardiometabolic Risk Factors, Cognitive Function
The Effect of Tart Cherry (Prunus Cerasus) Concentrate on Physiological and Cognitive Function
A randomized, double blind, counterbalanced, placebo controlled independent groups design to determine the effects of 3 month supplementation with tart cherry concentrate on indices of cardiometabolic health, exercise capacity…
- Conditions
- Cardiometabolic Risk Factors, Cognitive Function, Exercise Capacity
- Trial name
- NCT04021342
- Testing
- Montmorency tart cherry concentrate
- Where
- United Kingdom
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Healthy
Acute Effects of Spices on Pathways Associated With Glucose Homeostasis and Inflammation on PBMCs of Healthy Subjects
This study aims to investigate the effect of spices on gene expression of pathways associated with glucose homeostasis, oxidative stress and inflammation, in the postprandial phase in healthy human subjects.
- Trial name
- NCT02479334
- Testing
- Fat challenge breakfast, Fat challenge breakfast+spices, Carbohydrate challenge breakfast
- Where
- Sweden
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Lund University
Pediatric Obesity
Impact of Comprehensive Intervention on the Cardiometabolic Risk in Children With Central Obesity (IGENOI)Obesity
Central obesity, present in the metabolic syndrome (MS), is associated with increased risk of insulin resistance (RI). The aim of the project is to evaluate the protective effect of comprehensive intervention (Mediterranean diet…
- Trial name
- IGENOI (NCT03147261)
- Testing
- Lifestyle intervention
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Obese, Weight Loss
Effects of Adding L-BAIBA or L-BAIBA + Grains of Paradise to Exercising Adult Overweight and Obese Men and Women
The goal of this intervention study is to examine changes in body composition, weight loss, and cardio-metabolic risk factors after adding supplementation of L-Beta aminoisobutyric acid (L-BAIBA) and Grains of Paradise to…
- Conditions
- Obese, Weight Loss, Body Weight, Cardiometabolic Syndrome
- Trial name
- GOP (NCT05775003)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Lindenwood University