Clinical trials: Cardiometabolic Risk Factors
Child Obesity
Childhood Obesity Risk Assessment Longitudinal Study
Childhood obesity is a major public health problem worldwide. Europe has a high prevalence of obesity, which is accentuated in Mediterranean countries.
- Trial name
- CORALS (NCT06317883)
- Where
- 8 sites in Spain
- Volunteers
- 1,508 people, healthy volunteers welcome
- Sponsor
- Consorcio Centro de Investigación Biomédica en Red (CIBER)
Body Weight, Obesity
Meta-analysis of the Nordic Dietary Pattern on Cardiometabolic Risk and Cardiovascular Outcomes
The Nordic Diet is a dietary pattern rich in traditional Nordic foods, including berries, grains, and fatty fish common in northern Europe.
- Conditions
- Body Weight, Obesity, Overweight and Obesity, Obesity, Abdominal
- Trial name
- NCT04094194
- Testing
- Nordic diet
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Lifestyle Factors, Overweight and Obesity
Effect of Sleep Extension on Ceramides in People With Overweight and Obesity
The overall goal is to determine how a sleep extension intervention (increasing time in bed) in individuals who maintain less than 6.5 hours sleep per night affects their plasma ceramides and insulin sensitivity.
- Conditions
- Lifestyle Factors, Overweight and Obesity, Insulin Sensitivity, Eating Habit
- Trial name
- NCT06180837
- Testing
- Sleep Extension Intervention
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Utah
Metabolic Syndrome, Hypertension
Development and Multicenter Validation of an AI-Based Remote Photoplethysmography (rPPG) Facial Scan for Multimodal Health Assessment
The goal of this observational study is to learn if a non-contact facial scan using artificial intelligence (AI) can be used to check health status in adults living in urban areas such as Jakarta.
- Conditions
- Metabolic Syndrome, Hypertension, Diabetes (DM), Tachycardia
- Trial name
- NCT07491978
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Tarumanagara University
Obesity, Dietary Intervention
Effects of Boron and Mediterranean Diets on Gut Microbiota and Metabolic Health
This study investigated the effects of a boron-rich diet compared with a Mediterranean-style diet (Smart Alternative Food Formulation; SAFF) on obesity-related outcomes in adults.
- Conditions
- Obesity, Dietary Intervention, Gut Microbiota, Cardiometabolic Risk Factors
- Trial name
- BOR-SAFF (NCT07156097)
- Testing
- Mediterranean-style Diet (SAFF), Boron-rich Diet
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Dicle University
Abdominal Obesity
Effects of Weight Reduction on Sleep and Alertness in Long-distance Truck and Bus Drivers
The study is a year-long health-behaviour intervention in obese, male truck-drivers to lose weight moderately by 10%, using monthly individual counseling.
- Trial name
- SF-Truck (NCT00893646)
- Testing
- weight loss counseling
- Where
- 3 sites in Finland
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- UKK Institute
Metabolism Disorder, Insulin Sensitivity
Supervised Exercise-training in Children With Insulin Resistance or Healthy Metabolic Profile
Despite exercise training decrease blood fasting glycemia in 'average' terms, there is a wide interindividual variability after exercise training explored mainly in adults but not in children.
- Conditions
- Metabolism Disorder, Insulin Sensitivity, Obesity, Pediatric
- Trial name
- NCT03003754
- Testing
- High Intensity Training (HIT) + Resistance Training (RT), Control group
- Where
- Colombia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad Santo Tomas
Hypertension
Study of the Impact of Low Fat Dairy and High Fat Dairy Consumption on Daytime Ambulatory Blood Pressure
Market trends depicted by Agriculture and Agri-Food Canada suggest stagnation in cheese consumption, with potentially important impact on this key industry in Canada.
- Trial name
- GABA2 (NCT02763930)
- Testing
- Control diet, Milk diet, GABA-rich cheese diet
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Laval University
Overweight, Obesity
Meta-analyses of the Effect of Liquid Meal Replacements on Cardiometabolic Risk
Obesity is a major risk factor for cardiovascular disease and diabetes. Weight loss is an important therapeutic goal for overweight and obese patients to reduce their risk of developing cardiovascular disease and diabetes.
- Conditions
- Overweight, Obesity, Type 2 Diabetes
- Trial name
- NCT02779790
- Testing
- Liquid Meal Replacements
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- John Sievenpiper
Diet Modification, Cardiovascular Risk Factor
Bioavailability and Beneficial Properties of Coffee and Cocoa Bioactive Compounds
The aim of this study will be to define the bioavailability and the beneficial properties of coffee bioactive compounds. Moreover, the contribution of cocoa-based products containing coffee to the pool of circulating metabolites…
- Conditions
- Diet Modification, Cardiovascular Risk Factor, Nutritional and Metabolic Diseases
- Trial name
- P4L (NCT03166540)
- Testing
- cup of espresso coffee, cocoa-based products containing coffee
- Where
- Italy
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Parma
High-Intensity Interval Training
HIIT in Sedentary Obese Adults: Effects on Metabolic Risk, Body Composition, and FABP4
It is aimed to investigate the responses of Fatty Acid Binding Protein 4 (FABP4), which has been discovered as a novel biomarker of obesity and metabolic diseases, to regular exercise training.
- Trial name
- NCT06973980
- Testing
- Exercise
- Where
- Cyprus
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Physical Activity
Pedal@Work: A Worksite Wellness Program
The primary aim of this pilot study is to test the efficacy of a worksite intervention for reducing daily sedentary time and improving risk factors for cardiometabolic disease (e.g., measures of adiposity, anthropometrics…
- Trial name
- Pedal@Work (NCT01371084)
- Testing
- Pedal@Work Worksite Wellness, Pedal@Work
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Obesity
Intermittent Eating on Sustaining Weight-loss in Obesity
Weight regain after weight loss is a major problem in the treatment of obesity. Two novel types of intermittent fasting recently have received more attention: the 5:2 diet and time-restricted eating (TRE).
- Trial name
- INTEREST (NCT05453617)
- Testing
- Time-restricted eating, The 5:2 diet
- Where
- China
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Dyslipidemias, Overweight or Obesity
Efficacy of Pigmented Rice on Reducing Cardiometabolic Risk Factors Among Filipino Adults
The primary purpose of this clinical trial is to investigate whether the consumption of pigmented rice (black rice) in the diet improves cardiovascular health, specifically body weight, lipids, and glucose levels.
- Conditions
- Dyslipidemias, Overweight or Obesity, Hyperglycaemia (Non Diabetic)
- Trial name
- NCT06092632
- Testing
- Pigmented rice, White Rice
- Where
- Philippines
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Santo Tomas
Sleep, Cardiovascular Disease
Impact of Sleep Restriction in Women
The overall goal of this project is to test the hypothesis that long-term, sustained sleep restriction (SR), in women, will lead to increased cardio-metabolic risk.
- Conditions
- Sleep, Cardiovascular Disease, Obesity
- Trial name
- NCT02835261
- Testing
- Sleep Restriction
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Columbia University
Type 2 Diabetes
Effects of Exercise on sRAGE Levels and Cardiometabolic Risk Factors
The purpose of this study is to examine the effects of exercise on diverse cardiometabolic risk factors and indicators of atherosclerosis in patients with type 2 diabetes mellitus (T2DM).
- Trial name
- NCT01542775
- Testing
- Aerobic Exercise Group, Control Group
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Korea University
Obesity, Overweight
Microvascular and Metabolic Effects of High-intensity Interval Exercise Training
The study investigates the effects of high intensity interval training (HIIT) versus continuous training (CT), combined or not with fasting, on capillary density, microvascular function, cardiometabolic risk markers, functional…
- Conditions
- Obesity, Overweight, Physical Activity
- Trial name
- HIIT-FAST (NCT03236285)
- Testing
- High-intensity interval exercise training in the fed state, Continous exercise training in the fed state, High-intensity interval exercise training in the fasting state
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Cardiology, Laranjeiras, Brazil
Cardiovascular Disease, Diabetes
Effect of Vitamin D3 Supplementation on Cardiometabolic Risk
Supplementation studies with vitamin D have been performed where cardiometabolic risk markers have been assessed but these are few, and results are inconsistent. Hence, the purpose of this study is to determine: 1.
- Conditions
- Cardiovascular Disease, Diabetes, Bone Disease
- Trial name
- NCT02359214
- Testing
- Vitamin D3
- Where
- United Kingdom
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Chester
Metabolic Syndrome, Protection Against, Menopause
Diet, Cardiometabolic Risk (CM) and Menopause Symptoms
This research will explore the question 'What impact do the Mediterranean Diet (MedDiet) and the Heart UK Ultimate Cholesterol Lowering Plan (UCLP) Menopause have on cardiometabolic risk factors and the frequency and severity of…
- Trial name
- NCT05764473
- Testing
- The impact of MedDiet on cardiometabolic risk factors and menopause symptoms, The impact of UCLP on cardiometabolic risk factors and menopause symptoms
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Chester
Sensitivity Training Groups
Effect of Different Frequencies Weekly Training in Overweight/Obese Women
The aim of this study was to evaluate the effects of a resistance training programme of one or three times a week on body composition, cardiometabolic risk factors and handgrip strength in overweight and obese women
- Trial name
- NCT03410329
- Testing
- Resistance training
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Francesco Campa