Clinical trials: Cardiopulmonary Diseases
Cardiac Arrest
The Schmitz-Hinkelbein Method. A New Technique for CPR in Space.
The risk of a severe medical event during long-duration spaceflight is significant and can endanger both the whole mission and crew.
- Trial name
- NCT04354883
- Testing
- External Chest Compressions on Manikin in Underwater Setting
- Where
- Germany
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Köln
Breast Cancer, HER2-positive Breast Cancer
Study of Cardiopulmonary Exercise Testing in Women Who Have HER2-Positive Breast Cancer With Mild Cardiotoxicity
The purpose of this study is to find out how much oxygen is used during a cardiopulmonary exercise test (CPET) in women who have mild cardiotoxicity after standard treatment for HER2-positive breast cancer, and to see whether the…
- Conditions
- Breast Cancer, HER2-positive Breast Cancer, HER2-positive Metastatic Breast Cancer, Breast Cancer Stage I
- Trial name
- NCT05036252
- Testing
- Cardiopulmonary Exercise Test, Echocardiogram, Echocardiography
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Bypass, Cardiopulmonary
Menthol Massage for Post-Bypass Pain & Anxiety
This randomized controlled trial aims to evaluate the effectiveness of mentholated ointment massage in reducing pain and anxiety levels in patients who have undergone coronary bypass surgery, volunteered to participate in the…
- Trial name
- Menthol Care (NCT07508371)
- Testing
- Menthol Massage, Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Istanbul Medipol University Hospital
Acute Coronary Syndrome, Pulmonary Embolism
Assessment of Acute Disease to Reduce Imaging Costs
Overtesting for Acute Coronary Syndrome(ACS) and Pulmonary Embolism (PE) in low risk Emergency Department(ED) patients can increase exposure of nondiseased patients to radiation, intravenous contrast and anticoagulation.
- Trial name
- QUAADRICs (NCT01059500)
- Testing
- Webtool
- Where
- 4 sites in United States
- Volunteers
- 550 people
- Sponsor
- Wake Forest University Health Sciences
Obesity, Hypertension
Exercise Effects on Cardiometabolic Health and Sestrin-2 in Hypertensive Obese Women
Obesity is a chronic and complex disease characterized by excessive fat accumulation that adversely affects health and quality of life.
- Trial name
- SES-EX (NCT07370363)
- Testing
- Moderate-Intensity Continuous Exercise, Brisk Interval Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Havva Talay Çalış
Quality of Life, Congenital Heart Disease
Exercise Training in Children With Corrective Cardiac Surgeries
To determine the effects of preoperative exercise therapy on postoperative cardiopulmonary outcomes and quality of life in children with corrective cardiac surgeries.Within literature there is limited evidence on preoperative…
- Conditions
- Quality of Life, Congenital Heart Disease, Heart; Surgery, Heart, Functional Disturbance as Result
- Trial name
- NCT05763238
- Testing
- INTERVENTION GROUP, CONTROL GROUP
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Riphah International University
Hearing Loss, Cardiac Surgery
Prevalence of Auditory Dysfunction and ICU-acquired Delirium Following Cardiac Surgery With Cardiopulmonary Bypass: a Prospective Observational Study
AUDICS-ICU is a prospective observational aiming to evaluate the prevalence of auditive dysfunction following cardiac surgery. Participants will undergo audiometric testings before and 3 months after cardiac surgery with…
- Conditions
- Hearing Loss, Cardiac Surgery, Cardiopulmonary Bypass, Postoperative Cognitive Dysfunction
- Trial name
- AUDICS-ICU (NCT04151914)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- European Georges Pompidou Hospital
Cardiac Diseases, Cardio-pulmonary Bypass
A Monitoring System Based on the Multifactorial Dynamic Perfusion Index to Predict and Prevent the Onset of Postoperative Acute Kidney Injury After Cardiac Surgery, Based on a Dynamic Collection of Hemodynamic and Clinical Parameters During Cardiopulmonary Bypass
This project is based on a predictive alghorithm (Multifactorial Dynamic Perfusion Index-MDPI) already published and covered by a patent.
- Conditions
- Cardiac Diseases, Cardio-pulmonary Bypass, Acute Kidney Injury, Adult Cardiac Surgery
- Trial name
- PEQUOD 2 (NCT06786416)
- Testing
- PEQUOD
- Where
- Italy
- Volunteers
- 800 people
- Sponsor
- IRCCS Policlinico S. Donato
Medical Condition Requiring Extracorporeal Organ Support
The University of Freiburg Medical Center Extracorporeal Organ Support Device Registry
A prospective registry collecting pseudonymized clinical and treatment data from all patients treated with extracorporeal organ support (i.e., VV ECMO, VA ECMO, ECPR, Impella, IABP, and others) on the wards of the Department of…
- Trial name
- NCT05811780
- Where
- Germany
- Volunteers
- 1,500 people
- Sponsor
- University Hospital Freiburg
Myocardial Injury
Propofol Cardioprotection for Type II Diabetics
The purpose of this study is to determine if an intravenous anesthetic with antioxidant properties will protect the heart of diabetic patients from injury while undergoing coronary bypass surgery.
- Trial name
- NCT00734383
- Testing
- Propofol
- Where
- Canada
- Volunteers
- 137 people
- Sponsor
- University of British Columbia
Sudden Cardiac Arrest
HS Students Mandatory Universal Student Instruction in CPR Appraised Learning- Is the Mandate Working?
This study will help to provide better input to state health and education departments to improve the processes for CPR education.
- Trial name
- NCT04493970
- Testing
- High School Students Survey
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Kansas City Heart Rhythm Research Foundation
Cardiovascular Diseases
Cardiac Rehabilitation Program in Patients with Cardiovascular Disease
This protocol study aims to evaluate the effectiveness of a cardiac rehabilitation intervention program in patients with cardiovascular diseases to improve both anthropometric and biochemical data, as well as other variables…
- Trial name
- NCT06211361
- Testing
- Cardiac rehabilitation
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- University of Castilla-La Mancha
Kidney Failure, Intraoperative Complications
Hemodilution and Outcome in Cardiac Surgery
An hematocrit of 21-25% is supposed to perform the best organ protection during cardiopulmonary bypass for cardiac surgery. The investigators want to establish the best timing for a transfusion (in patients with a predicted low…
- Trial name
- NCT00364494
- Testing
- Different timing of red blood cells transfusion (substudy 1); Acute hemodilution versus no hemodilution (substudy 2)
- Where
- Italy
- Sponsor
- Università Vita-Salute San Raffaele
Chronic Obstructive Pulmonary Disease, Cor Pulmonale
Small Intestinal Absorption in Patients With Chronic Obstructive Pulmonary Disease and Cor Pulmonale
Aim: To investigate whether patients with pulmonary hypertension have reduced absorption capacity compared to COPD patients without cor pulmonale potentially due to venous obstruction in the portal vein system.
- Trial name
- NCT03243994
- Testing
- Absorption test with D-xylose and zink
- Volunteers
- 14 people
- Sponsor
- Jens Rikardt Andersen
Heart Diseases, Cardiovascular Diseases
Algorithmic Protamine Dosing for Reversal of Heparin After Cardiopulmonary Bypass
The PRODOSE trial is investigating a bespoke pharmacokinetic algorithm that calculates a tailored dose of protamine, required after cardiopulmonary bypass to reverse the action of heparin, based on individual patients and their…
- Trial name
- PRODOSE (NCT03532594)
- Testing
- PRODOSE Algorithm, Standard Care
- Where
- United Kingdom
- Volunteers
- 228 people
- Sponsor
- Papworth Hospital NHS Foundation Trust
Myocardial Ischemia
CPET in Myocardial Ischemia
The investigators goal is to determine whether cardiopulmonary exercise testing (CPET) can be utilized in the diagnosis of myocardial ischemia.
- Trial name
- NCT04067700
- Testing
- Invasive coronary treatment
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- Kuopio University Hospital
Pulmonary Hypertension, Mitral Regurgitation
Effect of Brief Nebulization of Milrinone on Pulmonary Arterial Pressure Before Cardiopulmonary Bypass on Mitral Valve Surgery Patients
Our main hypothesis is that inhalation of milrinone can reduce the elevated pulmonary arterial pressure due to severe mitral valve regurgitation without compromising systemic hemodynamics.
- Trial name
- NCT01621971
- Testing
- inhaled milrinone, intravenous milrinone
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Konkuk University Medical Center
Emergency Medicine, Endotracheal Intubation
Flexible Tip Bougie Catheter Intubation
We, therefore conducted a randomized cross over study to evaluate the usefulness of this new device use by experienced anesthesiologists in several airway manikin scenarios.
- Conditions
- Emergency Medicine, Endotracheal Intubation, Cardiopulmonary Arrest
- Trial name
- NCT03733158
- Testing
- the standard Bougie stylet for difficult intubation, The new Flexible Tip Bougie catheter
- Where
- Poland
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Lazarski University
Pleural Effusions Post Coronary Artery Bypass Graft, Hypoxia
Efficacy of 20% Human Albumin in Reducing Pleural Effusion After Cardiopulmonary Bypass
Human albumin is a widely used additive in cardiopulmonary bypass all around the world, but its effect on various outcomes has been debated.
- Conditions
- Pleural Effusions Post Coronary Artery Bypass Graft, Hypoxia, Hypoalbuminemia
- Trial name
- NCT06681415
- Testing
- Adding 100ml of 20% human albumin to cardiopulmonary bypass priming solution
- Where
- Latvia
- Volunteers
- 70 people
- Sponsor
- Pauls Stradins Clinical University Hospital
Low Cardiac Output Syndrome, Transposition of Great Vessels
Nitric Oxide During Bypass for Arterial Switch Operation
This trial will test if adding nitric oxide (NO) gas to the cardiopulmonary bypass (CPB) circuit in infants undergoing an arterial switch operation (ASO) for Transposition of the Great Arteries (TGA) changes the incidence of…
- Trial name
- NASO (NCT03661385)
- Testing
- Nitric Oxide
- Where
- 4 sites in Australia, Canada and 2 more
- Volunteers
- 300 people
- Sponsor
- Murdoch Childrens Research Institute
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.