Clinical trials: Cardiopulmonary Diseases
Dyspnea, Cardiopulmonary Dysfunction
Effect of Different Breathing Techniques on Dyspnea and Cardiopulmonary Parameters Among Patients After Open Heart Surgery
Open heart surgery is often associated with postoperative pulmonary complications, reduced lung expansion, dyspnea, and impaired cardiopulmonary function.
- Conditions
- Dyspnea, Cardiopulmonary Dysfunction, Postoperative Respiratory Dysfunction, Coronary Artery Disease
- Trial name
- NCT07591987
- Testing
- Segmental Breathing Exercises, Active Cycle Breathing Technique, Standard postoperative care
- Where
- 3 sites in Iraq
- Volunteers
- 99 people
- Sponsor
- University of Baghdad
Heart Failure
Effects of Early Cardiopulmonary Rehabilitation in Patients With Acute Decompensated Heart Failure
Acute decompensated heart failure (ADHF) is a severe condition characterized by rapid deterioration of cardiac function, leading to impaired oxygen delivery and multi-organ dysfunction.
- Trial name
- NCT07155421
- Testing
- Early Cardiopulmonary Rehabilitation, Routine in-hospital care
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Izmir Bakircay University
Cardiac Arrest
Cardiopulmonary Resuscitation Witnessing by a Relative
The bereavement generated by the loss of a family member can induce pathological situations: depressive state, anxiety, post-traumatic stress disorder and complicated grief.
- Trial name
- PRESENCE (NCT01009606)
- Testing
- Usual strategy, Modified strategy
- Where
- France
- Volunteers
- 570 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Blood Coagulation Disorders
The Effect of the Hemobag® Ultrafiltration System on Blood Conservation and Coagulation After Cardiopulmonary Bypass
This proposal is designed to mitigate hemodilution (blood diluted with an electrolyte solution) and loss of plasma proteins responsible for normal blood clotting as well as platelets at the completion of cardiopulmonary bypass…
- Trial name
- NCT01435304
- Testing
- method of returning residual CPB blood ( Hemobag®)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- MaineHealth
Chronic Heart Failure
Prognostic and Diagnostic Value of Biomarkers and Cardiac Functional Parameters in Patients With Chronic Heart Failure
The study aims to investigate whether disease progression in patients with chronic heart failure (CHF) can be assessed by new biomarkers, and determine their diagnostic value.
- Trial name
- NCT02776384
- Testing
- Observational study
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Heart Arrest
PreCoCa - "Prehospital Cooling With Cool-Caps"
This study shall investigate the feasibility of the use of cool-caps in the preclinical setting in patients with successful primary cardio-pulmonary resuscitation Hypothesis: cool-caps are efficient and feasible to use in the…
- Trial name
- NCT00398671
- Testing
- Application of cool cap after primary successful CPR
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Charite University, Berlin, Germany
Cardiovascular Diseases, Heart Diseases
Analysis of Longitudinal Cardiopulmonary Data
To define new national norms for pediatric blood pressure by adjusting the available data set of over 60,000 pediatric blood pressure readings for age, height and gender among children of normal body weight.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Lung Diseases, Hypertension
- Trial name
- NCT00005221
- Volunteers
- 60,000 people
- Sponsor
- Brigham and Women's Hospital
Cardiac Arrest, Cardiopulmonary Resuscitation
Quantitative Measurement of Cardiopulmonary Resuscitation (CPR) During In Hospital Cardiac Arrest
The design of this protocol is a prospective observational study to objectively measure the rate, depth and quality of chest compressions and ventilations delivered during cardiac arrest in the Pediatric Intensive Care Unit…
- Trial name
- Q-CPR (NCT00628693)
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Children's Hospital of Philadelphia
Sudden Cardiac Arrest
Research on Attitudes, Confidence, and Practical Skills in Performing Cardiopulmonary Resuscitation and Automated External Defibrillation After Completing a Course Based on the European Resuscitation Council Model
Research on attitudes, confidence, and practical skills in performing cardiopulmonary resuscitation and automated external defibrillation after completing a course based on the European Resuscitation Council model
- Trial name
- RACE-CPR (NCT07331831)
- Where
- Bulgaria
- Volunteers
- 656 people, healthy volunteers welcome
- Sponsor
- First Three Minutes Foundation
Ankylosing Spondylitis
Evaluation of Physical Performance in Ankylosing Spondylitis Patients
Ankylosing spondylitis (AS) can cause serious limitations in individuals' physical performance, as it involves the musculoskeletal system and can cause ankylosis and arthritis in both axial and peripheral joints.
- Trial name
- NCT04451681
- Testing
- Cardiopulmonary exercise test
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Post SARS-CoV2 (COVID-19)
Home-Based Exercise Tele-Rehabilitation After COVID-19
The Coronavirus Disease 2019 (COVID-19) pandemic has resulted in catastrophic infections and fatalities across the nation. Many older Veterans with comorbidities are especially vulnerable to complications and poor recovery.
- Trial name
- BOOST (NCT05425264)
- Testing
- Tele-exercise
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Tricuspid Regurgitation
Tricuspid Cardiopulmonary Exercise Study
Tricuspid regurgitation (TR), which in close to 90% of cases is functional as a consequence of left-sided heart failure, left heart valve abnormalities or pulmonary (vascular) disease, is associated with adverse patient outcomes…
- Trial name
- TRCPET (NCT04559256)
- Testing
- Cardiopulmonary Exercise Testing
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Heart and Diabetes Center North-Rhine Westfalia
Cardiac Arrest (CA)
Hand Position, CPR Quality and Rescuer Comfort
This randomized crossover simulation study will compare two hand positions used during chest compressions: interlocked fingers and non-interlocked hands placed one on top of the other.
- Trial name
- NCT07825805
- Testing
- Interlocked-finger chest compression technique, Overlapped hands chest compression technique
- Where
- Hungary
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Pneumothorax, Cardiac Surgery
Feasibility Study of Novice-Performed Lung Ultrasound for Pneumothorax Detection After Cardiac Surgery
What is the purpose of this study? This study is being done to find out if medical trainees (such as residents and fellows) can learn to use lung ultrasound to detect a collapsed lung (pneumothorax) after heart surgery.
- Conditions
- Pneumothorax, Cardiac Surgery, Lung Ultrasound, Chest Tube Removal
- Trial name
- CLEARVGRD (NCT07018856)
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Jacobo Moreno Garijo
COVID 19
Comparison of Cardiopulmonary Fitness Level With Normal Values After COVID-19
COVID-19 (Coronavirus disease 2019) is a new infectious disease caused by a virus named as SARS-CoV2 (Severe Acute Respiratory Syndrome Coronavirus-2).
- Trial name
- NCT04753346
- Testing
- Physical Activity Level, Anxiety and Depression Assessment, Exercise Capacity
- Where
- Turkey (Türkiye)
- Volunteers
- 240 people
- Sponsor
- Ankara University
Sarcopenia, Handgrip Strength Test
Preoperative Performance Indicators, Preoxygenation and Oxygen Reserve Relationship
The goal of this observational study is to evaluate the relationship between preoperative cardiopulmonary performance indicators and preoxygenation efficiency along with oxygen reserve depletion in patients scheduled for elective…
- Conditions
- Sarcopenia, Handgrip Strength Test, Preoxygenation
- Trial name
- NCT07688941
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Heart Arrest, Ventricular Fibrillation
AED Use in Out-of-Hospital Cardiac Arrest: A New Algorithm Named "One Shock Per Minute"
The aim of the trial is to evaluate a new AED algorithm that proposes a new timeline between the time devoted to administer a defibrillation shock, and the time devoted to chest compressions.
- Trial name
- DEFI2005 (NCT00139542)
- Testing
- One shock per minute AED protocol, Guidelines 2000 AED protocol
- Where
- France
- Volunteers
- 5,107 people
- Sponsor
- Fire Brigade Of Paris Emergency Medicine Dept
Eccentric Cycling Exercise Training
Effectiveness of Eccentric Cycling Exercise in Ambulatory Rehabilitation for Patients With Cardiopulmonary Diseases: A Pragmatic Randomized Controlled Trial
In eccentric cycling exercise (ECC), the cyclist must oppose backwards moving pedals on a specialized motor-driven ergometer. Throughout this process, the force applied on the pedals exceeds the torque generated by the…
- Trial name
- NCT07815366
- Testing
- Eccentric cycling exercise
- Where
- Switzerland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Out-of-Hospital Cardiac Arrest, Extracorporeal Cardiopulmonary Resuscitation
Left Ventricular Ejection Fraction in Cardiac Arrest Survivors Treated With Extracorporeal Cardiopulmonary Resuscitation
Extra-hospital cardiac arrest is a major public health problem, with approximately 46,000 cases per year. Nearly 71% of the patients for whom resuscitation was initiated did not present a return of spontaneous circulation on…
- Trial name
- FEVGECMO (NCT06046339)
- Testing
- Collection of data from the patient's medical file
- Where
- France
- Volunteers
- 116 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Oxidative Stress, Cognition Disorders
The Effect of Dexmedetomidine Infusion on Post-operative Cognitive Function and Oxidative Stress in Cardiac Surgery
Objective: The aim of this study was to determine the effect of dexmedetomidine in reducing postoperative cognitive dysfunction (POCD) in cardiac surgical patients which use cardiopulmonary bypass machine (CPB).
- Trial name
- NCT03054857
- Testing
- Dexmedetomidine
- Volunteers
- 100 people
- Sponsor
- Chulalongkorn University
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