Clinical trials: Cardiopulmonary Diseases
Out of Hospital Cardiac Arrest, Cardiac Arrest (CA)
Predicting 28-Day Survival in OHCA Patients
This prospective study aimed to identify clinical and laboratory predictors of return of spontaneous circulation (ROSC), 28-day survival, and favorable neurological outcomes in adult patients experiencing out-of-hospital cardiac…
- Trial name
- OHCAstd (NCT07023159)
- Testing
- Demographics, Comorbidities, Prehospital Variables
- Where
- Turkey (Türkiye)
- Volunteers
- 327 people
- Sponsor
- Haseki Training and Research Hospital
Out-of-hospital Cardiac Arrest
Application of Mechanical Cardiopulmonary Resuscitation Devices and Their Value in Out-of-hospital Cardiac Arrest: A Retrospective Analysis of the German Resuscitation Registry
The aim of this study was to analyse a large CPR database, the German Resuscitation Registry, to evaluate potential benefits of mechanical CPR devices over manual CPR in adult cardiac arrest victims.
- Trial name
- NCT02932124
- Testing
- mechanical chest compression device
- Volunteers
- 19,609 people
- Sponsor
- German Resuscitation Registry
Hypogammaglobulinemia, Congenital Heart Disease
Post-bypass Prophylactic IVIG in Infants and Neonates
The purpose of this study protocol is to determine if administering Intravenous Immunoglobulin (IVIG) for treatment of cardiopulmonary bypass (CPB) induced hypogammaglobulinemia in the early post-operative period can impact…
- Trial name
- NCT02043379
- Testing
- IVIG
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Alabama at Birmingham
Atelectasis
Lung Recruitment Improves Right Ventricle Performance
This study test whether a lung recruitment maneuver improves the right ventricle performance after cardiopulmonary bypass. Half of the patients received an standard protective ventilation and the other half the same ventilatory…
- Trial name
- NCT02795208
- Testing
- Lung recruitment maneuver
- Volunteers
- 40 people
- Sponsor
- Hospital Privado de Cordoba, Argentina
Cardiac Arrest, Cardiopulmonary Arrest
Quality of Pediatric Resuscitation in a Multicenter Collaborative
This is a prospective, observational, multi-center cohort study of pediatric cardiac arrests. The purpose of the study is to determine the association between chest compression mechanics (rate, depth, flow fraction, compression…
- Trial name
- pediRES-Q (NCT02708134)
- Where
- 63 sites in United States, Australia and 13 more
- Volunteers
- 7,000 people
- Sponsor
- Children's Hospital of Philadelphia
Optimal Sweep Gas Flow, Determination of Optimal Sweep Gas Flow for Different Phases of Cardiopulmonary Bypass
Re-Adjustment of Sweep Gas Flow to the During the Rewarming Period of the Cardiopulmonary Bypass
The investigators designed this prospective observational study with the theory that alkalosis caused by decreased CO2 solubility due to temperature increase during the rewarming period of the Cardiopulmonary Bypass could be…
- Trial name
- NCT06013189
- Testing
- Gas Flow Adjustment
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Acıbadem Atunizade Hospital
Advance Care Planning
CPR Decision Aid For Patients With Advanced Gynecologic Malignancies
The purpose of this research is to assess the effect of a cardiopulmonary resuscitation (CPR) decision aid video on CPR knowledge and end-of-life preferences in women with advanced gynecologic malignancy.
- Trial name
- NCT03251976
- Testing
- video, usual care
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Alabama at Birmingham
Cardiac Disease
Cardiac Deformation: Correlation With Conventional Echocardiographic Hemodynamic Variables (An Intraoperative Study)
The aim of this research is to apply cardiac tissue characterization in order to assess left ventricular function in cardiac surgical patients pre and post cardiopulmonary bypass.
- Trial name
- NCT00874991
- Where
- United States
- Volunteers
- 198 people
- Sponsor
- Weill Medical College of Cornell University
Cardiac Arrest, Cardiopulmonary Resuscitation
Mechanical Versus Manual Chest Compression
In this study, the investigators compared mechanical and manual chest compressions in out-of-hospital cardiac arrest cases.
- Trial name
- NCT04069377
- Testing
- LUCAS™ 2 Chest Compression System, Manuel chest compressions by human efforts
- Where
- Turkey (Türkiye)
- Volunteers
- 214 people
- Sponsor
- Ankara City Hospital Bilkent
Pulmonary Arterial Hypertension, Cardiovascular Diseases
Effects of Different Types of Physical Training in Patients With Pulmonary Arterial Hypertension.
Although there has been some progress in pharmacological management of PAH, limited functional capacity and low survival still persist, but there is evidence that exercise training can be accomplished without adverse effects or…
- Conditions
- Pulmonary Arterial Hypertension, Cardiovascular Diseases, Respiratory Disease, Hypertension, Pulmonary
- Trial name
- PAH (NCT03476629)
- Testing
- Physical activity
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- University of Nove de Julho
Refractory Angina
Allopurinol in Patients With Refractory Angina to Improve Ischemic Symptoms
Despite numerous advances in medical treatment and revascularization procedures for the treatment of patients with stable angina, debilitating symptoms that are unresponsive to conventional therapy may occur in patients…
- Trial name
- ARAMIS (NCT04368819)
- Testing
- Allopurinol 300 MG
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Ministry of Health, Brazil
Sickle Cell Anemia
Exercise Capacity in Pediatric Sickle Cell Anemia
The purpose of this study is to use comprehensive exercise testing to examine causes of exercise limitation in children and young adults with sickle cell anemia.
- Trial name
- NCT01527799
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Dyspnea; Cardiac
Test-Retest Reliability of Cardiopulmonary Exercise Testing With Echocardiography
CPETecho is progressively employed in diagnostic settings for pathophysiological detection, offering comprehensive assessment of both pulmonary and cardiac functions.
- Trial name
- REPEATCPETecho (NCT07281534)
- Testing
- CPETecho
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ziekenhuis Oost-Limburg
Abdominal Aortic Aneurysm
The Inter and Intra Reliability of Cardiopulmonary Exercise Testing in Abdominal Aortic Aneurysm Patients
Exercise testing is commonly being used in patients before surgery to test their overall fitness. One group it is being used in is patients who have an enlarged blood vessel in their stomach.
- Trial name
- CPEX (NCT02973308)
- Testing
- Observer
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Covid19
Dual MRI for Cardiopulmonary COVID-19 Long Haulers
The next phase of the COVID-19 pandemic is likely to see a surge in an associated chronic cardiopulmonary disease that will challenge health systems.
- Trial name
- NCT04828135
- Testing
- Hyperpolarized 129Xenon gas
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Bastiaan Driehuys
Heart Failure, Pulmonary Hypertension
Exercise Training to Improve Cardiopulmonary Hemodynamics in Heart Failure Patients
This research study is being done to find out if exercise therapy can help improve the heart function, overall health, and quality of life of patients with pulmonary hypertension caused by heart failure.
- Trial name
- NCT04909008
- Testing
- Exercise Training
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Pulmonary Hypertension
Inhaled Milrinone in Cardiac Surgery
The purpose of this study is to investigate the concentration-effect relationship of inhaled milrinone after prophylactic administration in cardiac surgical patients with preoperative pulmonary hypertension undergoing…
- Trial name
- NCT01725776
- Testing
- Inhaled milrinone 5 mg
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Montreal Heart Institute
Hematologic Disease and Disorders, Donors
Screening for Hematology Branch Protocols
This study allows the evaluation of subjects in order to determine their ability to safely participate in other active research studies.
- Conditions
- Hematologic Disease and Disorders, Donors, Healthy Volunteer
- Trial name
- NCT00001620
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Ischemic Heart Disease
Effects of Laugh Therapy Associated to Cardiopulmonary Rehab
Laugh is more than visual and vocal behave, is always followed by a series of physiological changes, including contractions of musculoskeletal system, increase of cardiac frequency by catecholamine release and hyperventilation…
- Trial name
- NCT02824120
- Testing
- Comedy, Documentary
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Out-Of-Hospital Cardiac Arrest, Ventricular Fibrillation
Real Time Amplitude Spectrum Area to Guide Defibrillation
AMSA trial is a multicenter, randomized, controlled study in out-of-hospital cardiac arrest patients. The purpose of the study is to test the hypothesis that a real time AMSA analysis during CPR may predict the success of…
- Trial name
- AMSA (NCT03237910)
- Testing
- AMSA, Defibrillation, CPR
- Where
- 2 sites in Italy
- Volunteers
- 31 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
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