Clinical trials: Cardiopulmonary Exercise Test
Mitral Stenosis
Assessment of Exercise Capacity, Muscle Oxygenation and Aortic Stiffness in Patients With Mitral Stenosis
Heart valve diseases are the most common cause of mortality and morbidity after coronary artery disease, hypertension, and heart failure.
- Trial name
- NCT07394998
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gazi University
Hyperbaric Oxygenation, Cardiorespiratory Fitness
Retrospective Analysis of CPET and Cognitive Tests of Healthy Individuals, Treated With 60 Treatment of HBOT
This retrospective observational study evaluates physiological and cognitive changes following a series of 60 hyperbaric oxygen therapy (HBOT) sessions in healthy individuals.
- Conditions
- Hyperbaric Oxygenation, Cardiorespiratory Fitness, Cognition
- Trial name
- HBOT (NCT07596641)
- Testing
- Hyperbaric Oxygen Therapy - HBOT
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Cardiopulmonary
Observational, Non-Interventional Study Supporting Validation of eVO2peak Using Results in Patients Receiving Standard of Care Cardiopulmonary Exercise Tests (CPET)
In this study, the hypothesis being explored is that peak VO2 and potentially other CPET parameters can be accurately estimated from biosignals (namely, motion from accelerometers and cardiopulmonary variables from EKG) collected…
- Trial name
- NCT05678530
- Where
- 16 sites in United States, Canada
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Prolaio
Healthy Adult Male and Female Volunteers
Neurocognitive Effects of Extended-Release Methylphenidate in Healthy Adults
This study evaluated the effects of methylphenidate (MPH), a stimulant medication commonly used to treat attention deficit hyperactivity disorder (ADHD), in healthy adults without ADHD.
- Trial name
- NCT07742631
- Testing
- Methylphenidate Stimulant medication therapy
- Where
- South Africa
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Witwatersrand, South Africa
Clinical Decision Support Systems, Cardiopulmonary Exercise Testing
Physician-Supervised GPT Assistance for Communicating Cardiopulmonary Exercise Test Results
Cardiopulmonary exercise testing requires clinicians to integrate multiple physiological measurements and explain their meaning, limitations, safety implications, and appropriate next steps.
- Trial name
- NCT07829731
- Testing
- Physician-Supervised GPT-Assisted Drafting, Physician-Only Drafting
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
Acute Cardiopulmonary Effects
Observation of Acute Cardiopulmonary Effects in Healthy Individuals Performing Cardiopulmonary Exercise Test (CPX) During Whole Body Vibration (WBV)
Observational study to evaluate acute cardiopulmonary effects of oscillatory whole body vibration (WBV) on healthy individuals analysed in non-invasive cardiopulmonary exercise test (CPX).
- Trial name
- GALILEOhealthy (NCT04162054)
- Testing
- Observational study to evaluate acute cardiopulmonary effects of whole body vibration (WBV) on healthy individuals analysed in non-invasive cardiopulmonary exercise test (CPX).
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Klinikum der Universität Köln
Atrial Fibrillation, Atrial Arrhythmia
Ergospirometry in Paroxysmal Atrial Fibrillation Prognosis
An observational, prospective, cohort study aiming to assess the potential predictive role of cardiopulmonary exercise testing in the prognosis of paroxysmal atrial fibrillation, in combination with echocardiographic indices and…
- Trial name
- PLACEBO (NCT05246423)
- Testing
- Observation group
- Where
- Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Healthy Obesity, Metabolically
Cardio-Pulmonary Exercise Testing in Healthy Population
Introduction: Cardiopulmonary exercise test (CPET) is a helpful tool for evaluation of aerobic exercise capacity and tolerance for variety of population.
- Trial name
- NCT05242211
- Testing
- exercise test
- Where
- Israel
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Chronic Obstructive Pulmonary Disease (COPD), Asthma (Diagnosis)
Breathlessness Perceptions Within Respiratory Diseases
Breathlessness is a complex symptom that results in poor quality of life, increased hospitalisations and increased mortality. Breathlessness is influenced by physiological, psychological and functional factors but these are…
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Asthma (Diagnosis), Interstitial Lung Disease (ILD), Bronchiectasis
- Trial name
- BiRD (NCT07648082)
- Where
- United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University Hospitals, Leicester
Ventilation, Exercise
Wetsuit and Life Jacket Induced Effects on Spirometry and VO2 in Windsurfers
The purpose of this study is to investigate the effect of wearing both neoprene suit and life jacket on respiratory capacities at rest and cardiopulmonary capacities during exercise in windsurfers.
- Trial name
- WINDSURF (NCT03440294)
- Testing
- resting standard spirometry, maximum exercise testing
- Where
- France
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Patients Post-COVID-19, Controls
Sequelae of COVID-19 With Focus on Exercise Capacity and Underlying Mechanisms
The project is designed as a cross-sectional study and aims to examine long-term consequences of coronavirus disease 2019 (COVID-19) for selected bio-behavioural parameters while taking the disease course severity into account.
- Trial name
- COR-PHYS (NCT05118711)
- Testing
- Cardiorespiratory fitness, Lung function, Muscular strength and balance tests
- Where
- Switzerland
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Arno Schmidt-Trucksäss
Cardiopulmonary Exercise Test, Anaerobic Threshold
Double Anaerobic Threshold in Athletes
During an incremental cardiopulmonary exercise test (CPET) performed with a ramp protocol, it is very important to determine the anaerobic threshold, defined as the point at which the metabolism switches from being predominantly…
- Conditions
- Cardiopulmonary Exercise Test, Anaerobic Threshold, Athlete
- Trial name
- NCT05770453
- Where
- 3 sites in Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Centro Cardiologico Monzino
Healthy Subject, Stage IA Breast Cancer
MRI and Cardio-Pulmonary Exercise Testing in Evaluating Exercise Intolerance in Patients With Stage I-III Breast Cancer After Chemotherapy Treatment
This pilot research trial studies magnetic resonance imaging (MRI) and cardio (heart)-pulmonary (lung) exercise testing in evaluating exercise intolerance in patients with stage I-III breast cancer after treatment with…
- Conditions
- Healthy Subject, Stage IA Breast Cancer, Stage IB Breast Cancer, Stage IIA Breast Cancer
- Trial name
- NCT02702830
- Testing
- Cardiopulmonary Exercise Testing, Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Breathing Exercises, Disability Physical
Effect of Inspiratory Muscle Training on Cardiopulmonary Capacity in Wheelchair Rugby Athletes
The goal of this clinical trial is to learn about in inspiratory muscle training on cardiorespiratory capacity, pulmonary function, respiratory muscle strength, sports skills, and quality of life of wheelchair rugby athletes.
- Conditions
- Breathing Exercises, Disability Physical, Athletes
- Trial name
- NCT06134778
- Testing
- Inspiratory Muscle Training
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Centro Universitário Augusto Motta
Postoperative Complications (Cardiopulmonary)
Preoperative Exercise Testing and Perioperative Outcomes
The goal of this observational study is to learn whether results from a brief exercise test done before surgery can help identify adults who may be more likely to have problems after moderate- to high-risk noncardiac surgery.
- Trial name
- SAMPO (NCT07519733)
- Testing
- Recruited participants receive preoperative rapid submaximal cardiopulmonary exercise testing within the current risk assessment framework of the pre-surgical evaluation clinic
- Where
- United States
- Volunteers
- 992 people, healthy volunteers welcome
- Sponsor
- Yale University
Exercise-Induced Bronchospasm
Effects of Montelukast on Occult Exercise-Induced Bronchospasm in Athletes
The purpose of this study is to determine if treatment of exercise-induced Bronchospasm with montelukast will help college athletes train more effectively and thus become more competitive in a non ergogenic manner.
- Trial name
- NCT00375232
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Indiana University
Cardiopulmonary, Exercise
COSMED K5 Validation and Reliability Study
To determine the validity of the K5 metabolic system breath-by-breath analysis setting during a high intensity treadmill running protocol compared to the criterion ParvoMedics TrueOne® 2400 automated metabolic gas analysis…
- Trial name
- K5 (NCT05145192)
- Testing
- COSMED K5 CPET (Cardiopulmonary Exercise Test), ParvoMedics CPET
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Medical Education, Cardiac Rehabilitation
Blended Cardiac Rehabilitation Training for Cardiology Residents
This randomized controlled trial compares supervised hospital-based practice with matched online activities as part of a common cardiac rehabilitation curriculum for cardiology residents.
- Trial name
- CR-BLEND (NCT07755878)
- Testing
- Common online cardiac rehabilitation curriculum, Matched supplementary online learning, Hospital-based case and practice sessions
- Where
- China
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Health Services Accessibility, Rural Health
Health Ahead Comparative Effectiveness Study
The Health Ahead Comparative Effectiveness Study is a pragmatic, parallel-arm interventional platform that systematically compares successive changes to preventive health screening on the path toward a fully automated screening…
- Conditions
- Health Services Accessibility, Rural Health, Medically Underserved Area, Preventive Health Services
- Trial name
- HACE (NCT07669168)
- Testing
- AI-Assisted Screening Interpretation (AI Reads), Human-Only Screening Interpretation
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- William Brandenburg, MD
Perioperative/Postoperative Complications, Aerobic Capacity
SHAPE Test for Preoperative Risk Stratification
This study is looking at whether a simplified exercise test called the SHAPE-HF cardiopulmonary testing system can be used before surgery in older adults.
- Trial name
- SHAPEPAT (NCT05743673)
- Testing
- Shape II
- Where
- United States
- Volunteers
- 371 people, healthy volunteers welcome
- Sponsor
- Yale University