Clinical trials: Cardiopulmonary Resuscitation (CPR)
Cardiopulmonary Resuscitation
Standard CPR Versus Chest Compressions Only
Background: More than two thirds of sudden cardiac arrests are witnessed by bystanders. Bystander cardiopulmonary resuscitation (CPR) doubles survival from cardiac arrest.
- Trial name
- NCT04569812
- Testing
- Cardiopulmonary Resuscitation
- Where
- Austria
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Cardiopulmonary Resuscitation, Educational Problems
Continuous Chest Compressions Training Among Schoolchildren With Gamification in Brazil: a Pilot Study
This study employed a randomized cluster intervention design to evaluate differences in chest compression depth among children's groups, using active learning methodologies and serious game-based learning as part of the Kids Save…
- Trial name
- CSC (NCT06565767)
- Testing
- cardiopulmonary resuscitation quality
- Where
- Brazil
- Volunteers
- 336 people, healthy volunteers welcome
- Sponsor
- Hospital Israelita Albert Einstein
Cardiopulmonary Arrest
Learning Curve of VL for Intubation During CPR
This is a clinical study based on analysis of video-clip data of endotracheal intubation (ETI) using videolaryngoscope (VL) and clinical data for cardiopulmonary resuscitation patients between 2012.03.01.-2015.02.28.
- Trial name
- NCT04114721
- Where
- South Korea
- Volunteers
- 250 people
- Sponsor
- Konkuk University Medical Center
Cardiopulmonary Resuscitation
CPR Education: Traditional Program Versus On-line Program
Out-of-hospital cardiac arrest (OHCA) is an important public health issue. Chang Gung Memorial Hospital, a university affiliated medical center in Taoyuan city, northern Taiwan, actively cooperated with the government policy to…
- Trial name
- NCT03586752
- Testing
- On-line program, Standard program
- Where
- Taiwan
- Volunteers
- 832 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Cardiopulmonary Resuscitations
Stress Coping Strategy on Perceived Stress Levels and Performance During a Simulated Cardiopulmonary Resuscitation
This study assessed the impact of a task-focusing strategy on perceived stress levels and performance during a simulated CPR scenario.
- Trial name
- NCT01826318
- Testing
- Stress coping
- Where
- Switzerland
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Cardiac Arrest
Non-invasive Neurological Evaluation During CPR
Cardiac arrest remains a leading cause of death, currently affecting >250,000 Europeans outside the hospital each year. Manual cardiopulmonary resuscitation (CPR) provides between 15 to 30 % of normal blood flow to the heart and…
- Trial name
- Neuro-E-CPR (NCT02684955)
- Testing
- Cerebral spectroscopy, Pupillometry
- Where
- 2 sites in France
- Volunteers
- 112 people
- Sponsor
- University Hospital, Grenoble
Leadership
Position of Teamleader and Leadership Performance
Investigation in simulated cardiac arrests. Team leaders are randomly designated. Designated teamleaders are instructed to lead their team from the position of the patient's head or remote from the patient.
- Trial name
- LeadPos (NCT04824508)
- Testing
- position
- Where
- Switzerland
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
BLS, Out-Of-Hospital Cardiac Arrest
Geographical Association Between Basic Life Support Courses, Bystander Cardiopulmonary Resuscitation and Survival
Background Since 2001 when the Danish Cardiac Arrest Registry was first established several large-scale interventions aimed at the entire Danish population from all ages have been initiated.
- Trial name
- Geodata-BLS (NCT04353089)
- Testing
- Basic life support courses
- Where
- Denmark
- Volunteers
- 900,000 people, healthy volunteers welcome
- Sponsor
- Emergency Medical Services, Capital Region, Denmark
Cardiac Arrest, Out-Of-Hospital
The REVIVE-PEEP Trial: Positive End-expiratory Pressure Versus Sham Valve/Zero End-expiratory Pressure in Cardiopulmonary Resuscitation During Manual Ventilation to Improve Neurological Outcomes at Discharge in Adult Patients Suffering an Out-of-hospital Cardiac Arrest
The goal of this clinical trial is to learn if applying positive end-expiratory pressure (PEEP) during cardiopulmonary resuscitation (CPR) improves neurological outcome in adults with out-of-hospital cardiac arrest who receive an…
- Trial name
- REVIVE-PEEP (NCT07905482)
- Testing
- Fixed PEEP Valve
- Where
- 3 sites in Netherlands
- Volunteers
- 3,200 people
- Sponsor
- Jeroen van Eijk
Cardiac Arrest, Pediatric ALL
Pediatric In-Hospital Cardiac Arrest International Registry (PACHIN)
: An intrahospital CA data recording protocol has been designed following the Utstein model. Database is hosted according to European legislation regarding patient data protection. It is drafted in English and Spanish.
- Conditions
- Cardiac Arrest, Pediatric ALL, In-hospital Cardiac Arrest
- Trial name
- PACHIN (NCT04675918)
- Testing
- Cardiac arrest
- Where
- Spain
- Volunteers
- 500 people
- Sponsor
- Jimena del Castillo
Endotracheal Intubation
Intubation During Cardiopulmonary Resuscitation
The aim of the study was to compare the intubation time and effectiveness, the grade of larynx visibility, and the ease of intubation in adults performed by nurses using 4 devices: a Macintosh blade laryngoscope (MAC), and a…
- Trial name
- NCT02804451
- Testing
- Macintosh laryngoscope, TruView EVO2 laryngoscope, TruView EVO2 PCD laryngoscope
- Where
- Poland
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Cardiopulmonary Resuscitation, Newborn Asphyxia
Comparison of Visual Instructions for Inserting a Laryngeal Mask in a Neonatal Mannequin.
This research project compares the effectiveness of two visual instructions for inserting laryngeal masks. Researchers will assess the procedure performed by undergraduate health students on neonatal mannequins.
- Trial name
- Neo-LMi (NCT06502327)
- Testing
- Instructions A, Instructions B
- Where
- Peru
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- National University of San Marcos, Peru
Cardiac Arrest, Extracorporeal Membrane Oxygenation Complication
Advanced Reperfusion Strategies for Refractory Cardiac Arrest
This is a Phase II, single center (Under the Center for Resuscitation Medicine at the University of Minnesota Medical School), partially blinded, prospective, intention to treat, safety and efficacy clinical trial, randomizing…
- Conditions
- Cardiac Arrest, Extracorporeal Membrane Oxygenation Complication, Ventricular Fibrillation, Pulseless Ventricular Tachycardia
- Trial name
- ARREST (NCT03880565)
- Testing
- Early Extracorporeal Membrane Oxygenation (ECMO) Facilitated Resuscitation, Standard Advanced Cardiac Life Support (ACLS) Resuscitation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Minnesota
Sudden Cardiac Arrest
Research on Attitudes, Confidence, and Practical Skills in Performing Cardiopulmonary Resuscitation and Automated External Defibrillation After Completing a Course Based on the European Resuscitation Council Model
Research on attitudes, confidence, and practical skills in performing cardiopulmonary resuscitation and automated external defibrillation after completing a course based on the European Resuscitation Council model
- Trial name
- RACE-CPR (NCT07331831)
- Where
- Bulgaria
- Volunteers
- 656 people, healthy volunteers welcome
- Sponsor
- First Three Minutes Foundation
Cardiac Arrest, Out-Of-Hospital, Cardiac Arrest With Successful Resuscitation
CardioPulmonary Resuscitation With Argon (CPAr) Trial
Preclinical studies suggest that argon (Ar) might diminish the neurological and myocardial damage after any hypoxic-ischemic insult.
- Trial name
- CPAr (NCT05482945)
- Testing
- Noble gas Argon
- Where
- 9 sites in Italy
- Volunteers
- 120 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Cardiac Arrest
The Feasibility and Safety of Head-up Cardiopulmonary Resuscitation in Patients With Non-traumatic Cardiac Arrest
Head up CPR with impedance threshold device(ITD) and active compression-decompression (ACD) has been proved to improve both cerebral and coronary perfusion pressure during resuscitation in animal models.
- Trial name
- NCT05609357
- Testing
- Head-up Cardiopulmonary Resuscitation
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
ECMO and Acute MI
Use of ECMO in Acute MI
ECMO offers an acceptable cardiopulmonary support in adults with similar hospital survival rates as other mechanical support. It is versatile and salvages some patients, who may otherwise die.
- Trial name
- NCT00425685
- Volunteers
- 60 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Cardiac Arrest Neonatal
Vasopressin vs. Epinephrine During Neonatal Cardiopulmonary Resuscitation
When a baby is born with a low heart rate or no heart rate, the clinical team must provide breathing support and chest compressions (what is call cardiopulmonary resuscitation or CPR).
- Trial name
- NCT05738148
- Testing
- Vasopressin, Epinephrine
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- University of Alberta
Basic Life Saving Skills, Cardiopulmonary Resuscitation
Does Contextual Interference Improve Retention of Basic Life Support Skills? A Randomized Controlled Trial
The current method of teaching Basic Life Support (BLS) courses involves a practice schedule where learners rotate through each station once, without repetition.
- Conditions
- Basic Life Saving Skills, Cardiopulmonary Resuscitation, Skill Retention
- Trial name
- NCT02381093
- Testing
- Modified BLS course, Standard BLS Course
- Where
- Canada
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Endotracheal Intubation, Cardiopulmonary Resuscitation
Bougies as Aid for Endotracheal Intubation Via Video Laryngoscopy During Continuous Chest Compressions
The goal of this clinical trials is to analyze the effects of using bougies as adjuncts on the performance of endotracheal intubation via video laryngoscopy during cardiopulmonary resuscitation in anesthesia residents.
- Conditions
- Endotracheal Intubation, Cardiopulmonary Resuscitation, Simulation
- Trial name
- NCT05689125
- Testing
- Railroaded bougie, Preloaded bougie, Stylet
- Where
- China
- Volunteers
- 65 people
- Sponsor
- Peking Union Medical College Hospital