Clinical trials: Cardiopulmonary Resuscitation (CPR)
Out-of-hospital Cardiac Arrest (OHCA), Cardiopulmonary Resuscitation (CPR)
The AIR-CPR Study: AI-Guided Chest Compressions
The AIR-CPR project aims to improve survival rates for patients with Out-of-Hospital Cardiac Arrest (OHCA) by utilizing Artificial Intelligence (AI) to optimize chest compression locations.
- Conditions
- Out-of-hospital Cardiac Arrest (OHCA), Cardiopulmonary Resuscitation (CPR), Aortic Valve Compression, Precision Resuscitation
- Trial name
- AIR-CPR (NCT07431710)
- Testing
- Device: AI-Enhanced Arterial Waveform Monitor (AIR-CPR App), AI-Guided Chest Compression Repositioning, Transesophageal Echocardiography (TEE)
- Where
- Taiwan
- Volunteers
- 255 people
- Sponsor
- Far Eastern Memorial Hospital
Heart Arrest
BC ECPR Trial for Out-of-Hospital Cardiac Arrest
The addition of an Extracorporeal-Cardiopulmonary Resuscitation (ECPR) service to a region may improve the survival of young patients with sudden unexpected cardiac arrest.The primary aim of this study is to determine the benefit…
- Trial name
- NCT02832752
- Testing
- ECPR Protocol
- Where
- 3 sites in Canada
- Volunteers
- 308 people
- Sponsor
- University of British Columbia
Out-Of-Hospital Cardiac Arrest
CPR Quality and Use of Feedback for OHCA
The purpose of this study is to investigate the quality of cardio-pulmonary resuscitation(CPR) delivered by EMS professionals and whether this quality can be improved by implementing real-time feedback during the event and an…
- Trial name
- NCT04152252
- Testing
- Real time feedback, Post-event debriefing
- Where
- Denmark
- Volunteers
- 2,989 people, healthy volunteers welcome
- Sponsor
- Emergency Medical Services, Capital Region, Denmark
Communication, Advance Directives
Choice of Diction's Effect
The purpose of the research is to determine how the language used when discussing preferences about cardiopulmonary resuscitation (CPR) affects decisions regarding this (code status)
- Conditions
- Communication, Advance Directives, Decision Making, Cardiopulmonary Resuscitation
- Trial name
- CODE (NCT04896411)
- Testing
- Alternative phrasing for no code, Standard of care for no code
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Heart; Arrest, Newborn, Birth Asphyxia
Does Higher (100% Oxygen) Versus Lower (21% Oxygen) During CC+SI During CPR of Asphyxiated Newborns Improve Time to ROSC
When newborn babies are born without a heartbeat the clinical team has to provide breathing and chest compressions (what is call cardiopulmonary resuscitation) to the newborn baby.
- Conditions
- Heart; Arrest, Newborn, Birth Asphyxia, Bradycardia Neonatal
- Trial name
- SURV1VE-O2 (NCT03902652)
- Testing
- Intervention (21% oxygen during CC+SI), Intervention (100% oxygen during CC+SI)
- Where
- Canada
- Sponsor
- University of Alberta
Cardiopulmonary Resuscitation (CPR), Basic Life Support Training Course
Evaluation of Mixed Reality Cardiopulmonary Resuscitation Training
<Study Design> This study is a cluster-randomized, stratified, non-inferiority trial designed to evaluate the feasibility, efficacy, and educational effectiveness of HEROS 4.0, a mixed-reality (MR)-based cardiopulmonary…
- Conditions
- Cardiopulmonary Resuscitation (CPR), Basic Life Support Training Course, Cardiac Arrest (CA)
- Trial name
- HEROS 4 (NCT07363772)
- Testing
- HEROS 4.0, Conventional CPR training
- Where
- South Korea
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Extracorporeal Cardiopulmonary Resuscitation, Cardiac Arrest
Observational Study to Assess Optimal ECPR Settings After Resuscitation
Rationale: Veno-arterial extracorporeal membrane oxygenation (vaECMO) during cardiopulmonary resuscitation (ECPR) might improve outcome after cardiac arrest.
- Trial name
- MOFE (NCT03592810)
- Testing
- Settings of the extracorporeal membrane oxygenation (ECMO)
- Where
- Netherlands
- Volunteers
- 26 people
- Sponsor
- Erasmus Medical Center
Cardiopulmonary Resuscitation
The Critical Threshold of Pulse Oximetry Plethysmographic Waveform Parameters in High Quality CPR
The purpose of this study is to analyze the relationship of the area under the curve (AUC) and/or the amplitude (Amp) of pulse oximetry plethysmographic waveform (POP) with partial pressure of end-tidal carbon dioxide (PETCO2)…
- Trial name
- NCT03754946
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Peking Union Medical College Hospital
Pulmonary Hypertension, Bronchopulmonary Dysplasia
Study of the Effect of Four Methods of Cardiopulmonary Resuscitation Instruction on Psychosocial Response of Parents With Infants at Risk of Sudden Death
OBJECTIVES: I. Describe the psychosocial response of parents and caretakers who learn cardiopulmonary resuscitation (CPR) techniques for infants at high risk for respiratory or cardiac arrest. II.
- Conditions
- Pulmonary Hypertension, Bronchopulmonary Dysplasia, Respiratory Distress Syndrome
- Trial name
- NCT00004805
- Testing
- CPR instruction
- Volunteers
- 500 people
- Sponsor
- National Center for Research Resources (NCRR)
Cardiopulmonary Arrest
Learning Curve of VL for Intubation During CPR
This is a clinical study based on analysis of video-clip data of endotracheal intubation (ETI) using videolaryngoscope (VL) and clinical data for cardiopulmonary resuscitation patients between 2012.03.01.-2015.02.28.
- Trial name
- NCT04114721
- Where
- South Korea
- Volunteers
- 250 people
- Sponsor
- Konkuk University Medical Center
Intraoperative Cardiac Arrest
Cardiopulmonary Resuscitation in Operating Room
In the last ten years patient safety during routine surgical interventions has increased; however as there is an increase in the number of specialized surgical interventions and high risk patients like elderly and emergency…
- Trial name
- CPR (NCT02884271)
- Testing
- cardiopulmonary resuscitation
- Where
- Turkey (Türkiye)
- Volunteers
- 7 people
- Sponsor
- Dokuz Eylul University
Cardiac Arrest
Amiodarone, Lidocaine or Neither for Out-Of-Hospital Cardiac Arrest Due to Ventricular Fibrillation or Tachycardia
The primary objective of the trial is to determine if survival to hospital discharge is improved with early therapeutic administration of a new Captisol-Enabled formulation of IV amiodarone (Nexterone-PM101) compared to placebo.
- Trial name
- ALPS (NCT01401647)
- Testing
- amiodarone, Lidocaine, Normal saline
- Where
- 9 sites in United States, Canada
- Volunteers
- 3,024 people
- Sponsor
- University of Washington
Nursing Caries, Cardiopulmonary Resuscitation
The Effect of Haptic and Highly Fidelity Simulator in Cardiopulmonary Resuscitation Training
Cardiopulmonary Resuscitation (CPR) is of great importance for nurses who frequently encounter cardiopulmonary arrest in health care institutions and who are within their duties, authorities and responsibilities.
- Trial name
- NCT05343221
- Testing
- High Fidelity Simulator, Haptic
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Cardiopulmonary Resuscitation Training
Immersive Virtual Reality Versus Manikin-Based Simulation for Cardiopulmonary Resuscitation Training
This study compared two methods for teaching cardiopulmonary resuscitation (CPR) to undergraduate medical students: immersive virtual reality and manikin-based simulation.
- Trial name
- NCT07802873
- Testing
- Immersive Virtual Reality CPR Training, Manikin-Based Simulation
- Where
- Iran
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Shiraz University of Medical Sciences
Out-Of-Hospital Cardiac Arrest, Cardiac Arrest
Technological and Patient-tailored Innovations for Maximizing Effectiveness of Cardiac Arrest Resuscitation
Out-of-hospital cardiac arrest (OHCA) affects 275,000 people in Europe every year. In Italy alone, 50,000 people experience OHCA annually, with only 9% surviving. Half of the survivors suffer severe brain damage.
- Trial name
- TIME-CARE (NCT06538155)
- Testing
- Wearable device, Cardiopulmonary resuscitation, CT scan, TEE exam, or chest X ray
- Where
- 3 sites in Italy
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Università Vita-Salute San Raffaele
Cardiopulmonary Resuscitation (CPR), ESCAPE ROOM
The Effect of Escape Room Simulation on Nursing Students' Clinical Decision-Making and Teamwork Attitudes Regarding Cardiopulmonary Resuscitation
The study was planned as a randomized controlled trial with a pre-test-post-test-follow-up design involving experimental and control groups.
- Trial name
- NCT07336511
- Testing
- Escape room
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Yildirim Beyazıt University
Simulated Pediatric CRP Ventilation
Simulation-based Comparative Study on Efficiency of Ventilation During Paediatric Cardiopulmonary Resuscitation
The aim of this study is to gather data to support beginning the pediatric cardiopulmonary resuscitation (CPR) with 5 initial breaths.
- Trial name
- PEDIVENT (NCT05345704)
- Testing
- cardiopulmonary resuscitation (CPR)
- Where
- Czechia
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Brno University Hospital
Cardiac Arrest, Heart Arrest
ECPR for Refractory Out-Of-Hospital Cardiac Arrest
In the U.S. alone, over 300,000 people per year have sudden out-of-hospital cardiac arrest (OHCA), and less than 1 out of 10 survive.
- Conditions
- Cardiac Arrest, Heart Arrest, Sudden Cardiac Arrest, Cardiopulmonary Arrest
- Trial name
- EROCA (NCT03065647)
- Testing
- Expedited Transport With Mechanical CPR
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Michigan
Out-of-Hospital Cardiac Arrest, Extracorporeal Cardiopulmonary Resuscitation
Refractory Cardiac Arrest Treated On Field By ECMO
Out-of-hospital cardiac arrest without resumption of spontaneous circulatory activity despite advanced medical resuscitation is considered refractory.
- Trial name
- ReCATOBE (NCT06397417)
- Testing
- Data collection
- Where
- France
- Volunteers
- 840 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Simulation Training
Effect of the Use of a Visual Feedback Device in RCP Trainings
To verify the efficacy of manikins with feedback in the training of physicians and nurses in the courses of Advanced Cardiac Life Support (ACLS) authorized by the American Heart Association (AHA) when compared to the traditional…
- Trial name
- NCT04338490
- Testing
- Feedback mannequim
- Where
- Brazil
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul