Clinical trials: Cardiopulmonary Resuscitations, open to volunteers
Cardiopulmonary Arrest
REBOA in Nontraumatic OHCA
The investigators propose a multicenter randomized controlled trial in South Korea and Taiwan to observe the clinical effects of REBOA on nontraumatic out-of-hospital-cardiac-arrest (OHCA) patients.
- Trial name
- REBOA (NCT06031623)
- Testing
- REBOA
- Where
- South Korea
- Volunteers
- 234 people
- Sponsor
- Seoul National University Hospital
Cardiac Arrest, Out-Of-Hospital Cardiac Arrest
Initial Double Sequential External Defibrillation in Out of Hospital Cardiac Arrest
Double Sequential External Defibrillation (DSED) represents an alternative treatment of refractory ventricular fibrillation (rVF) in out-of-hospital cardiac arrest (OHCA).
- Conditions
- Cardiac Arrest, Out-Of-Hospital Cardiac Arrest, Ventricular Fibrillation
- Trial name
- DUALDEFIB (NCT06672159)
- Testing
- Two defibrillators, One defibrillator
- Where
- Norway
- Volunteers
- 356 people
- Sponsor
- St. Olavs Hospital
Medical Condition Requiring Extracorporeal Organ Support
The University of Freiburg Medical Center Extracorporeal Organ Support Device Registry
A prospective registry collecting pseudonymized clinical and treatment data from all patients treated with extracorporeal organ support (i.e., VV ECMO, VA ECMO, ECPR, Impella, IABP, and others) on the wards of the Department of…
- Trial name
- NCT05811780
- Where
- Germany
- Volunteers
- 1,500 people
- Sponsor
- University Hospital Freiburg
Cardiac Arrest, Out-Of-Hospital, Hypotension
Cardiac Arrest - Ultrasound Detection of Occult Perfusion
The goal of this study is to describe the population of patients presenting after out of hospital cardiac arrest with occult perfusion, defined as a patient without a palpable pulse but with some evidence of pulsatile arterial…
- Trial name
- NCT07897370
- Where
- 8 sites in United States
- Volunteers
- 1,400 people
- Sponsor
- University of Massachusetts, Worcester
Cardiac Arrest, Pediatric ALL
Pediatric In-Hospital Cardiac Arrest International Registry (PACHIN)
: An intrahospital CA data recording protocol has been designed following the Utstein model. Database is hosted according to European legislation regarding patient data protection. It is drafted in English and Spanish.
- Conditions
- Cardiac Arrest, Pediatric ALL, In-hospital Cardiac Arrest
- Trial name
- PACHIN (NCT04675918)
- Testing
- Cardiac arrest
- Where
- Spain
- Volunteers
- 500 people
- Sponsor
- Jimena del Castillo
Cardiac Arrest (CA), Cardiopulmonary Resuscitation (CPR)
The OXY-VENT Study
Effective ventilation during cardiopulmonary resuscitation is essential but can be difficult to achieve consistently. Current practice relies on visible chest rise to guide ventilation volume, although this may not always…
- Trial name
- OXY-VENT (NCT07870551)
- Testing
- Ventilation Feedback Device (Active), Control (Recording-Only)
- Where
- Netherlands
- Volunteers
- 515 people
- Sponsor
- Jeroen van Eijk
Cardiac Arrest (CA)
Incidence of Colon Ischemia in Patients After Cardiopulmonary Resuscitation (CPR)
Bedside colonoscopy 24-36 hours after successful CPR
- Trial name
- NCT07359313
- Testing
- colonoscopy
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University Hospital Freiburg
Out-of-hospital Cardiac Arrest (OHCA)
Out-of-hospital Cardiac Arrest Epidemiology and Outcomes in Western Lithuania 2022-2028
Out-of-hospital cardiac arrest rate is common problem, because of high mortality rate. It is not clear incidence rate, epidemiology and outcomes in Lithuania
- Trial name
- NCT07622082
- Testing
- Protocol based
- Volunteers
- 4,000 people
- Sponsor
- Lithuanian University of Health Sciences
Out of Hospital Cardiac Arrest, Extracorporeal Cardiopulmonary Resuscitation
Rapid Prehospital ACcess to ECPR in Prague
A prospective pilot feasibility study of prehospital ECPR in patients with refractory OHCA
- Trial name
- RACE (NCT06789978)
- Testing
- Extracorporeal cardiopulmonary resuscitation (ECPR)
- Where
- Czechia
- Volunteers
- 20 people
- Sponsor
- General University Hospital, Prague
Resuscitation, Extra Corporeal Life Support
PERCEPTION - Super-Early Neuroprognostication in eCPR Patients
Background Extracorporeal cardiopulmonary resuscitation (eCPR) is a rescue therapy for a selected group of patients. Extracorporeal membrane oxygenation (ECMO) is initiated to bypass the cardiac system and bridge time to…
- Conditions
- Resuscitation, Extra Corporeal Life Support, ECMO, Extracorporeal Cardiopulmonary Resuscitation
- Trial name
- PERCEPTION (NCT07584187)
- Testing
- Automated Pupillometry, continuous near-infrared spectroscopy (cNIRS)
- Where
- Austria
- Volunteers
- 45 people
- Sponsor
- Medical University of Vienna
ExtraCorporeal Membrane Oxygenation (ECMO), Cardiac Arrest
Plasma Biomarkers and Platelet Morphology of Extracorporeal CardioPulmonary Resuscitation
Extracorporeal cardiopulmonary resuscitation (ECPR) constitutes a pivotal emergency intervention for cardiac arrest (CA) patients.
- Trial name
- ECPR (NCT07113769)
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Central China Fuwai Hospital of Zhengzhou University
Refractory Cardiac Arrest
Feasibility Study on a Prehospital Extracorporeal CardioPulmonary Resuscitation in the Pavia's Province.
This is a single Center interventional study, assessing the feasibility of a complex treatment strategy where an in-hospital standard care process is applied in an out-of-hospital cardiac arrest.
- Trial name
- eCPR on Site (NCT07155772)
- Testing
- Extracorporeal CardioPulmonary Resuscitation (eCPR)
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Out-Of-Hospital Cardiac Arrest
Enhanced Community First Responder System Evaluation in Singapore
The rise in out-of-hospital cardiac arrest (OHCA) cases in Singapore highlights the need for effective bystander cardiopulmonary resuscitation (BCPR).
- Trial name
- TCPR-Link (NCT06530433)
- Testing
- CPRCard + TCPR Link App and Web, CPRCard Only
- Where
- Singapore
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Pediatric Advanced Life Support (PALS)
Comparing the Effectiveness of Large Language Model-Based and Video-Based Refresher Education on Knowledge Retention After Simulation-Based Pediatric Cardiopulmonary Resuscitation Training: A Six-Month Follow-Up Study
This study aims to compare the effectiveness of large language model (LLM)-based refresher education and video-based refresher education for maintaining knowledge and performance after simulation-based Pediatric Advanced Life…
- Trial name
- NCT07783932
- Testing
- LLM-Based Refresher Education, Video-Based Refresher Education
- Where
- South Korea
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Education Advancement
Airway Obstruction During BLS
Appropriate management of cardiac arrest (immediately and technically well performed) is a priority that must be taught to all citizens and future healthcare personnel, including future physicians.
- Trial name
- BLS-OBST (NCT06770920)
- Testing
- use of an observer tool when not role-playing
- Volunteers
- 112 people
- Sponsor
- Université Paris-Sud
Out of Hospital Cardiac Arrest, Computed Tomography
Timing for Computed Tomography and Post-Resuscitation Care on Short-Term Outcomes in Out-of-Hospital Cardiac Arrest
This retrospective multicenter study investigates the association between the timing of computed tomography (CT) scans and short-term outcomes in adult non-traumatic out-of-hospital cardiac arrest (OHCA) patients who achieved…
- Trial name
- NCT06936917
- Volunteers
- 5,000 people
- Sponsor
- National Taiwan University Hospital
Cardiopulmonary Resuscitation, Cardiac Arrest
Cardiac Arrest Bundle of cARE Trial
An out-of-hospital cardiac arrest is a sudden event where the heart stops beating and a person becomes unresponsive. During this event, vital organs in the body receive no blood flow, causing them to shut down.
- Conditions
- Cardiopulmonary Resuscitation, Cardiac Arrest, Out of Hospital Cardiac Arrest
- Trial name
- CABARET (NCT05917717)
- Testing
- Neuroprotective 'bundle of care'
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Coma, Heart Arrest
Predictive Outcome in Comatose Patients
Evaluating the prognosis of comatose patients after cardiac arrest (CA) in the intensive care unit (ICU) remains challenging. It requires a multimodal approach combining standardized clinical examination, serum biomarkers…
- Conditions
- Coma, Heart Arrest, Cardiopulmonary Resuscitation
- Trial name
- PRECOM (NCT05321459)
- Testing
- Neurological prognosis
- Where
- 7 sites in France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cardiac Arrest, Out-Of-Hospital
Validity of ICU Clinician's Appraisal of Proportionality in CPR
The VICAP-CPR study investigates whether doctors and nurses working in Intensive Care can determine neurological outcome and future quality of life after six months in patients treated for cardiac arrest outside the hospital…
- Trial name
- VICAP-CPR (NCT07026773)
- Where
- 9 sites in Austria, Belgium and 6 more
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Ghent
Cardiopulmonary Resuscitation (CPR), ESCAPE ROOM
The Effect of Escape Room Simulation on Nursing Students' Clinical Decision-Making and Teamwork Attitudes Regarding Cardiopulmonary Resuscitation
The study was planned as a randomized controlled trial with a pre-test-post-test-follow-up design involving experimental and control groups.
- Trial name
- NCT07336511
- Testing
- Escape room
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Yildirim Beyazıt University