Clinical trials: Cardiorespiratory Responses
Sepsis, Septic Shock
Central Venous Catheter Colonisation Among Critically Ill Patients in Intensive Care Units
Background: Central Venous catheter insertion technique and indwelling time are major risk factors for CVC colonisation. Colonisation occurs through microbial migration and biofilm formation along the catheter insertion tract.
- Conditions
- Sepsis, Septic Shock, Post-cardiac Surgery, Post-Cardiorespiratory Arrest Coma
- Trial name
- NCT03270774
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Makerere University
Apnea of Prematurity, Preterm Birth
Hemodynamic Responses to Cardio-respiratory Events in Preterm Infants
Intermittent episodes of hypoxemia and/or bradycardia, also defined as cardio-respiratory events (CRE) are very frequent in preterm infants and may result in transient hypoxia and hypoperfusion of target organs, with possible…
- Conditions
- Apnea of Prematurity, Preterm Birth, Patent Ductus Arteriosus, Hypoxia, Brain
- Trial name
- NCT04184245
- Where
- Italy
- Volunteers
- 42 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Autonomic Nervous System, Cardiorespiratory Parameters
Musical Auditory Stimulation and Exercise
Check the effects of musical auditory stimulation on the autonomic modulation and cardiorespiratory parameters during and after aerobic exercise.
- Trial name
- NCT03200483
- Testing
- Control Protocol, Classical Music Protocol, Rock Music Protocol
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Acute Respiratory Infection, Sepsis
Capnodynamic Monitoring of Cardiorespiratory Function in Critically Ill Patients
Capnodynamic monitoring has the potential to offer continuous and non-invasive measurements of heart and lung function in patients requiring ventilation in an intensive care setting.
- Conditions
- Acute Respiratory Infection, Sepsis, Postoperative Respiratory Distress
- Trial name
- PROFICIENT (NCT05082168)
- Testing
- Capnodynamic monitoring
- Where
- Australia
- Volunteers
- 100 people
- Sponsor
- South West Sydney Local Health District
COPD
The Acute Cardiorespiratory Response to Blood-flow Restricted Versus Traditional Exercise Training Regimens (CaRe BFR)
The investigators hypothesize that BFR exercise regimens result in a different acute cardiorespiratory response pattern compared to traditional exercise regimens.
- Trial name
- CaRe-BFR (NCT05163600)
- Testing
- BFR-CYC 50% peak / 50% AOP (exhaustive), BFR-CYC 3x2min, BFR Resistance 80% LOP
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Coronary Artery Bypass Grafting, Coronary Artery Disease
Cardiac and Endothelial Function Response to Early Exercise Training After Coronary Artery Bypass Surgery
Background: Coronary artery bypass grafting (CABG) due to coronary artery disease (CAD) is one of the main surgical procedures performed in the area of cardiology.
- Conditions
- Coronary Artery Bypass Grafting, Coronary Artery Disease, Cardiac Rehabilitation
- Trial name
- CEFREET (NCT03096158)
- Testing
- Ventilatory Muscle Training (TREMVEN), Aerobic Training (AERO), Isometric Handgrip Training (ISO)
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Sound Exposure, Exercise Performance
Effect of High-Level Headphone Sound Exposure on Exercise Responses in Young Healthy Individuals
This study will investigate the effect of high-level headphone sound exposure on cardiorespiratory responses and perceived exertion during a submaximal treadmill exercise test in young healthy individuals.
- Trial name
- NCT07556666
- Testing
- High-Level Headphone Sound Exposure, No-Sound Headphone Condition
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Stroke
Physiological Responses During Overground Gait Training With a Wearable Exoskeleton After Stroke
To investigate the acute physiological responses during 20-minute overground gait training with a wearable exoskeleton in persons after stroke
- Trial name
- NCT03653780
- Testing
- Ekso GT
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Vrije Universiteit Brussel
Obstructive Sleep Apnea, Hypertension
Cardiorespiratory Responses to Exercise in Elderly
Elderly have a high prevalence to systemic arterial hypertension (SAH) and obstructive sleep apnea (OSA). Both comorbidities are closely associated and inflict injury cardiorespiratory capacity.
- Trial name
- NCT03307928
- Testing
- Cardiopulmonary Exercise Test Protocol, Polysomnography Assessment
- Where
- Brazil
- Volunteers
- 28 people
- Sponsor
- Federal University of Paraíba
Rheumatoid Arthritis
Study of the Response and Cardiorespiratory Endurance in Early RA Patients Treated With Tocilizumab or Methotrexate
To measure the CRE by a work capacity index obtained in a submaximal testing (W65%/kg) in early RA patients treated with tocilizumab compared to Methotrexate alone.
- Trial name
- TOMERA (NCT01245452)
- Testing
- Tocilizumab, Methotrexate
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Patrick Durez
Cooling Fabrics, Exercise Performance
Cooling Fabrics and Exercise Performance in Endurance Athletes
In humans, the primary means of cooling the body during exercise is through the evaporation of sweat from the skin surface. Clothing represents a layer of insulation that hinders the evaporation of sweat from the surface of the…
- Conditions
- Cooling Fabrics, Exercise Performance, Thermoregulation
- Trial name
- NCT02016521
- Testing
- Cooling Fabric
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- McGill University
Covid19, SARS-CoV2 Infection
Coronaltitude - Multicentric Evaluation of the Impact on Hypoxia Sensitivity of Patients With COVID-19
In this study, the investigators will examine the extent to which having suffered coronavirus disease 2019 (COVID19) impacts one's sensibility to hypoxia by means of the 'Richalet test'.
- Conditions
- Covid19, SARS-CoV2 Infection, Hypoxia, Altitude
- Trial name
- NCT05167357
- Testing
- COVID19
- Where
- France
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Institut de Formation et de Recherche en Médecine de Montagne
Atrial Fibrillation
The Effect of Beta-blocker on Chronotropic Response and Cardiorespiratory Fitness in Patients With Atrial Fibrillation
This is a prospective study to evaluate changes in exercise capacity and chronotropic response to exercise before and after beta-blocker dosage reduction in patients with atrial fibrillation (AF).
- Trial name
- NCT05332457
- Testing
- Reduced dosage of beta-blocker
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Adolescents, Physical Activity
School-based HIIT and Dose-Response Effects
There are experimental evidences of the importance of high intensity exercises in health outcomes improvement. However, there are limited knowledge about possibility to affect health outcomes in adolescents through exercises…
- Conditions
- Adolescents, Physical Activity, Adipose Tissue, Blood Pressure
- Trial name
- PEER-HEART (NCT06431230)
- Testing
- standard high-intensity interval training, plyometric high-intensity interval training
- Where
- Poland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Wroclaw University of Health and Sport Sciences
Dyspnea, Muscle Strain
Muscle Reflex Inhibition in Hypoxic Exercise
The goal of this interventional study is to compare muscle reflex function under settings of normoxia (normal oxygen level), acute hypoxia (brief oxygen-lack) and chronic hypoxia (long-duration exposure to oxygen-lack).
- Trial name
- NCT05619887
- Testing
- Fentanyl, Saline
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Adult, Fatigue
Recovery, Fatigability, and Proteomic Response to Aerobic Exercise Training in Healthy Individuals
The purpose of this protocol is to investigate the role of expired non-metabolic carbon dioxide in the relationship between fatigability and recovery and the response to aerobic exercise training in healthy individuals.
- Trial name
- NCT03800342
- Testing
- Aerobic Exercise Training
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- George Mason University
Exhaustion - Physiological
Physiologic Adaptations to Interval and Continuous Running at Low Volume and Vigorous Intensity Over 14-Weeks.
The purpose of this study was to verify physiological responses to constant-load (continuous) vs. variable-intensity (interval) during 14 weeks of aerobic exercise on active men.
- Trial name
- NCT01816451
- Testing
- running training
- Where
- Brazil
- Volunteers
- 35 people
- Sponsor
- University of Trás-os-Montes and Alto Douro
Exercise, Cardiorespiratory Fitness
Addressing Individual Variability in Response to Exercise
In this proposal, the investigators challenge the assumption that following the physical activity guidelines implies benefit for ALL adults, and that if benefit is not achieved in response to first line therapy, it will be by…
- Trial name
- NCT04304092
- Testing
- Exercise
- Volunteers
- healthy volunteers welcome
- Sponsor
- Dr. Robert Ross
Peripheral Arterial Disease, Coronary Artery Disease
Efficacy of Cardiac Rehab for Patients With Peripheral Artery Disease Versus Patients With Coronary Artery Disease
Exercise is commonly recommended as a treatment for patients who present with peripheral artery disease (PAD). Although a great deal of research has supported the efficacy of exercise rehabilitation for PAD, it is infrequently…
- Conditions
- Peripheral Arterial Disease, Coronary Artery Disease, Vascular Diseases
- Trial name
- NCT03394183
- Testing
- Cardiac Rehabilitation
- Where
- Canada
- Sponsor
- University Health Network, Toronto
Athletic Performance
Effects of High-Intensity Interval Training (HIIT) on Physiological Responses in Alpine Skiers
The aim of this study was to investigate the effects of high-intensity interval training (HIIT) on anaerobic performance and cardiorespiratory responses in alpine skiing athletes.
- Trial name
- HIIT-ALP (NCT07904481)
- Testing
- High-Intensity Interval Training (HIIT), Regular Alpine Skiing and Strength Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- TUNC ILCIN