Clinical trials: Cardiovascular Condition
Postexercise Hypotension
Histamine as a Molecular Transducer of Adaptation to Exercise
This study is investigating the role of histamine in generating adaptation to exercise
- Trial name
- NCT05206227
- Testing
- Aerobic Exercise, alpha-FMH, Resistance and Aerobic Exercise
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Depression, Anxiety
Cardiovascular Biomarkers and Quetiapine in Depression and Anxiety Patients
No suitable treatment has been identified to reverse and ideally prevent, the cardiovascular disease risk associated with depression and anxiety.
- Trial name
- NCT00951483
- Testing
- Quetiapine-XR
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Loyola University
Smoking Cessation, Psychiatric Illness
Reducing Cardiovascular Disease by Combining Smoking Cessation Pharmacotherapy and Behavioural Counseling
Research Aims The aims of this research study are: 1. To determine which of the following three smoking cessation medications is most effective in achieving cessation: Nicotine Patch Nicotine Patch + gum or inhaler Varenicline…
- Trial name
- RW (NCT01623505)
- Testing
- Champix, Transdermal Nicoderm patch combined with gum or inhaler, Transdermal Nicoderm patch
- Where
- Canada
- Volunteers
- 738 people, healthy volunteers welcome
- Sponsor
- Ottawa Heart Institute Research Corporation
Von Willebrand Diseases
Study of VGA039 in Healthy Volunteers and Patients With Von Willebrand Disease (VIVID)
The VIVID study is structured in a master protocol format comprised of multiple parts that evaluate intravenous (IV) and subcutaneous (SC) VGA039 in healthy volunteers and subjects with von Willebrand Disease (VWD) and other…
- Trial name
- NCT05776069
- Testing
- VGA039
- Where
- 25 sites in United States, Australia and 6 more
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Vega Therapeutics, Inc
Metabolic Syndrome
The Effect of Allopurinol on Insulin Resistance and Blood Pressure
Studies in animals have found that allopurinol can markedly improve fructose induced metabolic syndrome. In this study we test the hypothesis that allopurinol may lower BP, reduce triglycerides, and improve metabolic parameters…
- Trial name
- NCT00639756
- Testing
- Allopurinol
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital Mateo Orfila
Aortic Stenosis, Hypoplastic Left Heart Syndrome
Fetal Intervention for Aortic Stenosis and Evolving Hypoplastic Left Heart Syndrome
For fetuses with severe aortic stenosis, in utero balloon aortic valvuloplasty may improve fetal growth of left heart structures and thus improve potential for biventricular repair strategies after birth.
- Trial name
- NCT01736956
- Testing
- Fetal Aortic Valvuloplasty
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Bicuspid Aortic Valve
Bicuspid Aortic Valve (BAV) Registry
The purpose of this registry is to gather information on patients with bicuspid aortic valve disease.
- Trial name
- BAV (NCT01756222)
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Family Caregivers, Stroke
Caregiver Self-Management Needs Through Skill-Building
Caring for a family member after a stroke can be very difficult and worsen the physical and mental health of untrained caregivers.
- Trial name
- NCT03635151
- Testing
- Telephone Assessment and Skill-Building Kit (TASK III) Group, Information Support and Referral (ISR) Group
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Myocardial Infarction, Chronic Periodontitis
The Effect of Periodontal Therapy in Chronic Periodontitis Patients With and Without Acute Myocardial Infarction
The aim of this study was to evaluate the effects of periodontal treatment on gingival crevicular fluid (GCF) levels of Neopterin(N) and vascular cell adhesion molecule (VCAM-1) in chronic periodontitis(CP) patients with acute…
- Trial name
- NCT03005886
- Testing
- Periodontal examination, GCF sampling, phase I therapy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gazi University
Heart Failure, Caregivers
Heart Failure Resilience Intervention for Caregivers
Heart failure (HF) patients with supportive caregivers have better physical health, emotional health, and quality of life. But caregivers have an increased risk of caregivers' own worsening health and often feel a sense of burden…
- Trial name
- HEROIC (NCT03963583)
- Testing
- HEROIC
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cardiovascular Risk Factor
Surveillance of Cardiovascular Risk Factors in Cameroonian Garrison
Purpose: The objective of our study was to assess the cardiovascular risk of a Cameroonian military population and compare it to the cardiovascular risk of the neighboring civilian population.
- Trial name
- NCT04315441
- Testing
- STEPS and AUDIT questionnaires
- Volunteers
- 566 people, healthy volunteers welcome
- Sponsor
- Support and Education Technic Centre
Diabetic Retinopathy (DR)
Diabetic Retinopathy Screening Point-of-Care Artificial Intelligence
This research study is being conducted to improve eye care by using artificial intelligence (AI) to make diabetic eye screenings faster and more accessible.
- Trial name
- DRES POCAI (NCT06721351)
- Testing
- Diabetic Retinopathy screening Point of Care Artificial Intelligence
- Where
- 3 sites in United States
- Volunteers
- 548 people, healthy volunteers welcome
- Sponsor
- Centro De Salud La Comunidad De San Ysidro Inc DBA: San Ysidro Health
Heart Failure, ESKD
Study of Diastolic Dysfunction in ESKD in Hemodialysis Patient
To Asses the prevalence , pattern , and severity of diastolic dysfunction in patients ESKD undergoing regular dialysis and to investigate its correlation with clinical parameters dialysis-related factors and echocardiographic…
- Conditions
- Heart Failure, ESKD, Hemodialysis Patients
- Trial name
- NCT07180888
- Testing
- Echocardiography, Echocardiographic assessment of diastolic dysfunction
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Type 2 Diabetes, Pregnancy
Fat Metabolism in Pregnancy and Neonatal Heart Function in Diabetes
Background: The health of the next generation is likely programmed in the womb (i.e.in utero), and our understanding of how that programming happens will allow us to favorably influence the health of future generations.
- Trial name
- NCT01346527
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Cardiopulmonary Arrest, Pediatric ALL
Impact of 2 Resuscitation Sequences on Management of Simulated Pediatric Cardiac Arrest
The International Liaison Committee on Resuscitation regularly publishes a Consensus on Science with Treatment Recommendations but guidelines can nevertheless differ when knowledge gaps persist.
- Conditions
- Cardiopulmonary Arrest, Pediatric ALL, Resuscitation
- Trial name
- NCT05474170
- Testing
- AHA resuscitation sequence, ERC resuscitation sequence
- Where
- Switzerland
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Geneve TEAM Ambulances
Hypercholesterolemia, Hypertension
Effectiveness of Nigella Sativa (Kalonji) Seed in Dyslipidemia
This is a pilot study. The aim of the investigators' study is to evaluate the effectiveness of nigella sativa seed in the treatment of dyslipidemia.
- Conditions
- Hypercholesterolemia, Hypertension, Diabetes Mellitus, Metabolic Syndrome X
- Trial name
- NCT00327054
- Testing
- Nigella sativa seed
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Cardiovascular Diseases, Lung Diseases
Swedish CArdioPulmonary bioImage Study 2
In the Swedish CArdioPulmonary bioImage Study (SCAPIS 1), 30,154 randomly selected men and women, aged 50-64 years, were recruited from six areas in Sweden during 2013-2018.
- Trial name
- SCAPIS2 (NCT06679777)
- Where
- 6 sites in Sweden
- Volunteers
- 30,154 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Osteoporosis, Osteopenia
Melatonin Osteoporosis Prevention Study
Osteoporosis is one of the most common skeletal disorders. Today in the United States, 10 million individuals have osteoporosis and 34 million more have low bone mass or osteopenia, which places them at an increased risk of some…
- Trial name
- MOPS (NCT01152580)
- Testing
- melatonin, sugar pill
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Duquesne University
CVD
EEG/MECG/EMG Evaluating the Severity of Aortic Stenosis, Heart Failure and Ischemic Stroke Through an Artificial Intelligenceassisted System.
The specific objectives and methods of this project are: (1) To test the feasibility and accuracy of integrating EEG, MECG and EMG for detecting the severity of diseases such as aortic stenosis, heart failure and ischemic stroke.
- Trial name
- NCT05716659
- Where
- Taiwan
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Cardiovascular Diseases
Pragmatic, Randomized Evaluation of Statin Active Choice to Reach Improved Outcomes Based on Evidence
In this study, the investigators will conduct a pragmatic, cluster-randomized, controlled trial to evaluate an active choice intervention with and without social comparison feedback to increase physician statin prescribing rates…
- Trial name
- PRESCRIBE (NCT03021759)
- Testing
- Active choice, Social comparison feedback
- Where
- United States
- Volunteers
- 4,774 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
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