Clinical trials: Cardiovascular Condition
Transthyretin Amyloid Cardiomyopathy (ATTR-CM)
Thailand ATTR-CM Registry
The investigators of this registry aim to study the natural history, clinical presentation, characteristics, and imaging findings of patients diagnosed with ATTR amyloidosis in Thailand longitudinally.
- Trial name
- NCT06338696
- Testing
- No intervention
- Where
- 8 sites in Thailand
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Coronary Artery Disease
HsTnT in Stable Coronary Artery Disease
Coronary artery disease (CAD) is one of the leading causes of morbidity and mortality worldwide. Life threatening manifestations such as acute myocardial infarction (AMI) and sudden cardiac death are the most important causes of…
- Trial name
- NCT01954303
- Testing
- Progress of CHD
- Volunteers
- 965 people, healthy volunteers welcome
- Sponsor
- University Hospital Heidelberg
Atherosclerosis
Office Practice Assessment of Carotid Atherosclerosis Using Handheld Ultrasound (OPACA) Study
The purposes of this study are to determine: 1. Inter-site variability in CIMT image measurement using SonoCalcTM. 2. If non-sonographer health care professionals working in an office practice setting can be trained to follow a…
- Trial name
- NCT00258973
- Testing
- Carotid Ultrasound performed in office practice
- Where
- United States
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Pre-Eclampsia, Eclampsia
Prospective Study in Pregnant Women With Hypercoagulopathy
Pre-eclampsia is one of the most common causes of maternal and fetal morbidity and mortality. The aim of this study is to identify pregnant women at risk for pre-eclampsia or other cardiovascular complications at a very early…
- Trial name
- NCT00215969
- Where
- 2 sites in Denmark
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Hillerod Hospital, Denmark
Cardiovascular Disease, Dietary Modification
Effects of Reduction in Saturated Fat on Cholesterol and Lipoproteins in Lean and Obese Persons
A randomized controlled clinical trial comparing the effect of substitution of unsaturated fat from nuts and oils for saturated fat from meat and dairy foods on serum lipids in normal weight and obese subjects with elevated LDL…
- Conditions
- Cardiovascular Disease, Dietary Modification, Cardiovascular Risk Factors
- Trial name
- NCT02589769
- Testing
- unsaturated fat for saturated fat, saturated fat
- Where
- Norway
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Ambulatory Blood Pressure Monitoring, Home Blood Pressure Monitoring
Novel BP Monitoring Methods to Study the Association Between Sleep BP Patterns and BP Values in Daily Life
Out-of-office blood pressure (BP) measurement by means of ambulatory BP monitoring (ABPM) or home BP monitoring (HBPM) is recommended for the diagnosis and management of hypertension in the latest guidelines.
- Conditions
- Ambulatory Blood Pressure Monitoring, Home Blood Pressure Monitoring, Blood Pressure Determination, Arterial Hypertension
- Trial name
- CABER-NET (NCT05781256)
- Where
- Italy
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
Cardiac Arrest, Sudden Death, Cardiac
Use of Public Access Defibrillators by Untrained Bystanders
Survival from out-of-hospital cardiac arrest is time critical and diminishes rapidly without appropriate intervention. Bystander CPR at least doubles the chances of survival and the additional use of a public access defibrillator…
- Trial name
- NCT03230773
- Testing
- Defibrillator model
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Morbid Obesity, Bariatric Surgery Candidate
Rivaroxaban Versus Enoxaparin for Prophylaxis of Venous Thromboembolism in Bariatric Surgery
Rivaroxaban versus enoxaparin for prophylaxis of venous thromboembolism in morbidly obese patients undergoing bariatric surgery: An open_label randomized controlled trial
- Trial name
- NCT06689241
- Testing
- Enoxaparin, rivaroxaban
- Where
- Egypt
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Cardiac Arrest (CA)
Hand Position, CPR Quality and Rescuer Comfort
This randomized crossover simulation study will compare two hand positions used during chest compressions: interlocked fingers and non-interlocked hands placed one on top of the other.
- Trial name
- NCT07825805
- Testing
- Interlocked-finger chest compression technique, Overlapped hands chest compression technique
- Where
- Hungary
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Murmur, Heart, Rhythm; Abnormal
Evaluation of Cardiags Trimod for Analysis of Cardiac Activity
The current study concerns Cardiags Trimod, a new non-invasive medical device for cardiac examinations. The evaluation of its effectiveness is done relative to specific standard devices.
- Trial name
- EVALTRIMOD (NCT05162599)
- Testing
- Diagnostic study, experimental evaluative cross-sectional study
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- CARDIAGS
Pregnancy, Gestational Diabetes Mellitus (GDM)
Polyphenol Intake, Mediterranean Diet Adherence, and Oxidative Stress in Pregnancy
This study is a randomized controlled clinical trial designed to evaluate the effect of a polyphenol-rich dietary intervention during pregnancy on endothelial function, oxidative stress biomarkers, and maternal and neonatal…
- Conditions
- Pregnancy, Gestational Diabetes Mellitus (GDM), Preeclampsia, Hypertension, Pregnancy-Induced
- Trial name
- PREGPOLY (NCT07656532)
- Testing
- Natural Non-Alkalized Cocoa, Polyphenol-Rich Dietary Counseling
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Stroke
Development of a Genomics-based Multimodal Prediction Model for Post-stroke Vascular Dementia
To collect large-scale multimodal data, including genomic information, neuroimaging, neurophysiological measures, cognitive assessments, and clinical characteristics from stroke survivors and healthy controls.
- Trial name
- NCT07660263
- Where
- South Korea
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Seyoung Shin
Ischemic Stroke
Discovering Patterns in the Gut Microbiota Associated With the Risk of Stroke and the Outcome After a Stroke and Integration of These Data With Genomic Information to Find New Drug Targets and New Treatments to Improve Neurological Evolution and Functional Status of Stroke Patients.
The composition of the intestinal microbiota is associated with the risk of stroke and with post-stroke neurological evolution. At the same time, the genetics and epigenetics of each patient are associated with the composition of…
- Trial name
- MAESTRO (NCT04795687)
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Carotid Stenosis, Surgery
Revascularization of Extracranial Carotid Artery Stenosis
Investigate the current situation of carotid stenosis therapy in China. Establish the data bank of carotid stenosis revascularization (CAS and CEA) in China ,in order to get best quality control of the therapy, as well as confirm…
- Conditions
- Carotid Stenosis, Surgery, Stroke
- Trial name
- RECAS (NCT01994187)
- Testing
- Carotid endarterectomy, carotid angioplasty
- Where
- China
- Volunteers
- 2,100 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
COVID-19
Non-contact ECG Sensor System for COVID19
The purpose of this study is two-fold. First we would like to confirm that non-contact ECG provides equivalency to current contact methods of obtaining ECG data.
- Trial name
- NCT04341506
- Testing
- Non-contact ECG
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Northwestern Medicine
Dyspnea, Heart Failure
Systolic Time Intervals a Prognostic Tool of Heart Failure in Emergency Departement (STI/AHF)
The performance of STIs and clinical scores alone and their combination to predict short term prognosis of acute decompensated heart failure.
- Trial name
- NCT03831204
- Testing
- biopac, prognostic scores
- Where
- Tunisia
- Volunteers
- 642 people, healthy volunteers welcome
- Sponsor
- University of Monastir
Sleep Apnea, Obstructive, Hypertension
Mechanisms for Individual Differences in Hypertension in Obstructive Sleep
Hypertension is a common consequence of obstructive sleep apnea (OSA). However, not all individuals with OSA have hypertension and there are major individual differences in blood pressure response to positive airway pressure…
- Trial name
- PISA-BP (NCT03176732)
- Testing
- Positive Airway Pressure
- Where
- 2 sites in United States, Iceland
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Congenital Diaphragmatic Hernia, Pulmonary Hypoplasia
Feto-Endoscopic Tracheal Occlusion (FETO) for Severe Congenital Diaphragmatic Hernia
Tracheal occlusion IDE approved by FDA for congenital diaphragmatic hernia fetuses.
- Conditions
- Congenital Diaphragmatic Hernia, Pulmonary Hypoplasia, Pulmonary; Hypertension
- Trial name
- FETO (NCT02986087)
- Testing
- Fetal Tracheal Occlusion
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Stroke
Upper Limb Function and Visuospatial Exploration After Stroke
This project is a cross-sectional, observational mono-center study with prospective data collecting. This study aims to further explore quality of upper limb movement in relation to characteristics of visuospatial exploration in…
- Trial name
- NCT03135093
- Testing
- No intervention
- Where
- Switzerland
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Heart Failure
Clinical Validation Study for CPM Device
This study is designed to be a clinical validation study to ready the CPM System for FDA 510(k) submission. This study will be conducted as a prospective non-randomized.
- Trial name
- NCT05445206
- Testing
- CardioPulmonary Management Device (CPM)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Analog Device, Inc.
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