Clinical trials: Cardiovascular Condition
HIV/AIDS, Hypertension
Evaluating the Impact of a Community Health Worker Program in Neno, Malawi
This protocol concerns the implementation and evaluation of an intervention designed to realign the existing cadre of Community Health Workers (CHW) in Neno District, Malawi to better support the care needs of the clients they…
- Conditions
- HIV/AIDS, Hypertension, Asthma, Diabetes
- Trial name
- NCT03106727
- Testing
- Household model
- Where
- Malawi
- Volunteers
- 122,395 people, healthy volunteers welcome
- Sponsor
- Partners in Health
Atrial Fibrillation
Evaluation of Ablation Lesions Using Cardiovascular Magnetic Resonance Imaging
Ineffective ablation lesions can cause arrhythmia recurrence after catheter ablation for cardiac arrhythmia. Ablation lesions can be created with various ablation energy modalities.
- Trial name
- ENABLE-CMR (NCT05432024)
- Testing
- Catheter ablation
- Where
- Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- R&D Cardiologie
Hypertension
Acute Effects of Beet Juice Intake on the Vascular Function of Hypertensive Patients
To assess the acute effects of only one dose of beet juice on hypertensive subjects treated with vascular endothelial function parameters, using the microvascular reactivity method.
- Trial name
- NCT04020796
- Testing
- Beetroot juice
- Where
- Brazil
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Pedro Ernesto
Atherosclerosis
Women's Isoflavone Soy Health (WISH) Trial
The purpose of this study is to determine whether soy supplementation can reduce hardening of the arteries and cognitive decline in postmenopausal women.
- Trial name
- NCT00118846
- Testing
- 25 gm soy protein supplement
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Peripheral Vascular Diseases, Cardiovascular Disease
Vascular Regenerative Cell Exhaustion in Adults With Peripheral Artery Disease (PAD-VRCE)
PAD-VRCE is an observational, cross-sectional, two arm study aimed at determining if the presence of peripheral artery disease (PAD) can influence the number of circulating regenerative cells in blood.
- Conditions
- Peripheral Vascular Diseases, Cardiovascular Disease, Type 2 Diabetes, Peripheral Artery Disease
- Trial name
- PAD-VRCE (NCT06626646)
- Where
- 2 sites in Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Canadian Medical and Surgical Knowledge Translation Research Group
Stroke, Healthy
WIM Exosuit Wearable Soft Robot for Enhancing Walking Activity
This study is to develop, test, and optimize a soft hip wearable robot for individuals with stroke, Parkinson's, multiple sclerosis, or older adults with no neurologic deficits.
- Trial name
- NCT07061691
- Testing
- WIM Robotic Exoskeleton
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Stroke
Stroke, Measurement and Rehabilitation
The main aim of the study was to investigate the effects of transcranial laser stimulation together with neuromuscular electrical stimulation (NMES) in post-stroke patients.
- Trial name
- LTNMES (NCT05497791)
- Testing
- transcranial laser stimulation associated with NMES
- Where
- Brazil
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Congenital Heart Disease, Mechanical Ventilation Complication
Mechanical Ventilation During Cardiopulmonary Bypass
The study is about a protocol of protective mechanical ventilation during cardiopulmonary bypass used during cardiosurgery for the correction of congenital heart diseases, to evaluate what's the best for the lungs
- Conditions
- Congenital Heart Disease, Mechanical Ventilation Complication, Cardiopulmonary Bypass
- Trial name
- VENICE (NCT03629574)
- Testing
- Ventilation during cardiopulmonary bypass
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera di Padova
Cardiovascular Diseases, Chronic Disease
Nutrigenomics Diet Intervention Study Comparing Effects of Western and Balanced Diet in Healthy Subjects
Diet macronutrient relative composition, quality and quantity determines lifestyle disease, including cardiovascular disease, development.
- Trial name
- Foodgene (NCT00733018)
- Testing
- "Western" versus "balanced" macro nutrient diet composition
- Where
- Norway
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Vascular Diseases
Cognitive Training in Stroke Patients
The study aims to investigate the behavioral effects, neural correlates and functional connectivity of cognitive training in patients with stroke
- Trial name
- NCT03644290
- Testing
- Cognitive training, Control Condition
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- São Paulo State University
Pathological Processes, Cardiomyopathies
Adenosine as an Adjunct to Blood Cardioplegia
Myocardial protection is a major issue in cardiac surgery, since inadequate protection increases the risk of postoperative cardiac dysfunction.
- Trial name
- NCT02681913
- Testing
- Adenosine
- Where
- Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Amphia Hospital
Stroke
Get With the Guidelines-Stroke Registry
Get With The Guidelines-Stroke is a program for improving the quality of care for patients hospitalized with stroke by promoting consistent adherence to the latest evidence-based clinical practice guidelines.
- Trial name
- GWTG-Stroke (NCT02693223)
- Testing
- GWTG Stroke program
- Where
- United States
- Volunteers
- 3,892,063 people, healthy volunteers welcome
- Sponsor
- American Heart Association
Non Hodgkin Lymphoma, Hodgkin Lymphoma
Thiotepa-based Conditioning for Allogeneic Stem-cell Transplantation (SCT) in Lymphoid Malignancies
The study hypotheses is that the introduction of dose escalated thiotepa, in substitution to busulfan or melphalan, will reduce toxicity after allogeneic transplantation while improving disease eradication in patients with…
- Conditions
- Non Hodgkin Lymphoma, Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, Multiple Myeloma
- Trial name
- NCT02507479
- Testing
- Thiotepa
- Where
- 2 sites in Israel
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Lysosomal Storage Diseases
Screening of Lysosomal Storage Disorders Diseases in Minority Groups
Aim is to undertake a screening study that identifies undiagnosed patients with LSDs and determine the prevalence of these diseases with special focus on underrepresented minority groups.
- Trial name
- NCT03812042
- Testing
- Enzyme assay and molecular sequencing
- Where
- United States
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Lysosomal and Rare Disorders Research and Treatment Center, Inc.
Cardiac Arrest (CA)
The Effect of Virtual Reality-Assisted Escape Room Experience
The aim of this study is to improve associate degree Dialysis Program students' Basic Life Support (BLS) knowledge and skills through a virtual reality (VR)-supported escape room intervention.
- Trial name
- VR (NCT07846124)
- Testing
- Virtual Reality-Supported Escape Room Training, Control Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ege University
Cardiovascular Diseases, Heart Diseases
Examining Psychosocial Mediators of Exercise Behavior
The purpose of this study is to examine psychosocial mediators of exercise behavior.
- Trial name
- NCT00142688
- Testing
- Physical activity, Wellness
- Where
- United States
- Volunteers
- 448 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Health, Subjective, Nutrition Disorders
Relative Energy Deficiency in Sport Multicenter Study
Relative Energy Deficiency in Sport (RED-S) characterizes a range of negative health and performance outcomes that result from chronically low energy availability.
- Conditions
- Health, Subjective, Nutrition Disorders, Athletic Injuries, Hormone Disturbance
- Trial name
- NCT04766203
- Testing
- Treatment of REDS using a holistic treatment arm
- Where
- Canada
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Trent Stellingwerff
Cardiovascular Diseases
Inter-field Strength Agreement of CMR Derived Strain
Magnetic Resonance Imaging (MRI) scanners create a strong magnetic field around the body to produce a detailed picture of parts of the body. This can provide a lot of useful information about how the heart looks and works.
- Trial name
- NCT04475627
- Testing
- Cardiovascular Magnetic Resonance (CMR) imaging at 1.5T, Cardiovascular Magnetic Resonance (CMR) imaging at 3T
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Orthostatic Hypotension, Syncope
The Effect of Water Carbonation on Orthostatic Tolerance
The primary purpose of this investigation is to determine whether water carbonation can improve orthostatic tolerance in healthy control volunteers.
- Conditions
- Orthostatic Hypotension, Syncope, Vasovagal Syncope
- Trial name
- NCT05621460
- Testing
- 500mL carbonated water, 500mL still water, 50mL still water
- Where
- Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Simon Fraser University
Photodamage
Laser 360iQ: Optimal Light-laser Combination Therapy
To assess the safety and efficacy of light-laser combination therapy for the improvement of skin color, tone, texture and laxity
- Trial name
- NCT04519723
- Testing
- Assess the safety and efficacy of light-laser therapy using the Harmony XL and Dye-VL (500-600nm), Q-Switched 1064nm, Er:YAG 2940nm modules in combination .
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Alma Lasers Inc.
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