Clinical trials: Cardiovascular Condition
Aortic Valve Disease, Aortic Aneurysm
Aortopathy Relationship To Imagery and Kinocardiography Features (ARTIK)
Kinocardiography (KCG) is a portable measurement technique developed to estimate cardiac mechanical performance by studying the vibrations produced by myocardial contraction during each heartbeat and transmitted to the body…
- Trial name
- ARTIK (NCT06286358)
- Testing
- Kinocardiography
- Where
- Belgium
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Université Libre de Bruxelles
Cerebral Tumor, Stroke
Magnetic Resonance Imaging Evaluation of the Tissular Oxygen Saturation in Brain
The purpose of this study is to measure the tissular oxygen saturation in brain by magnetic resonance imaging on subjects and to correlate the results with near infrared spectroscopy measurements.
- Trial name
- GADOXY (NCT02317055)
- Testing
- imaging
- Where
- France
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Stroke, Knowledge, Attitudes, Practice
Effects of an Educational Intervention on Rehabilitation Clinicians' Practices for Health-related Outcomes After Stroke
The overall aim of this pilot study is to evaluate the feasibility of a study protocol for a future stepped wedge cluster randomized clinical trial (c-RCT) that will investigate the effects of an innovative KT intervention on 1)…
- Conditions
- Stroke, Knowledge, Attitudes, Practice, Physical Disability, Motor Skills Disorders
- Trial name
- NCT03807115
- Testing
- Implementation of stroke mobility guidelines
- Where
- 6 sites in Canada
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- McGill University
Congenital Heart Disease, Aortic Root Dilatation
Predictors of Aortic Root Dilatation in Tetralogy of Fallot Patients
To predict vulnerable patients for aortic root dilatation in TOF patients using CT as a reliable imaging modality, thus aiding early intervention, and identifying those who will require strict follow-up.
- Conditions
- Congenital Heart Disease, Aortic Root Dilatation, Tetralogy of Fallot
- Trial name
- NCT06081855
- Testing
- CT
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Assiut University
Overweight, Obesity
Fat-Associated Cardiovascular Organ Dysfunction
This is an observational study of cardiovascular risk factors and arterial or cardiac function in subjects with overweight or obesity.
- Trial name
- FATCOR (NCT02805478)
- Testing
- There is no intervention
- Where
- Norway
- Volunteers
- 618 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Tricuspid Valve Insufficiency
"Atriogenic Tricuspid Selected, Omics Profile, Multimodality Imaging and Clinical Outcomes"
The aim of our study is to investigate the molecular mechanisms underlying remodeling of the tricuspid valve apparatus in patients with ITF and isolated AF, in comparison with patients with ITF from right ventricular remodeling…
- Trial name
- ATOMIC (NCT05724225)
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Inflammation
The Effect of Tomato Ketchup on Inflammation
The purpose of this study is to determine the inhibiting effects of a single consumption of tomato ketchup on inflammation which will be induced ex-vivo in human blood.
- Trial name
- NCT01462825
- Testing
- tomato ketchup meal
- Where
- Netherlands
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Age-related Macular Degeneration, Diabetic Retinopathy
Village-Integrated Eye Worker Trial II
The vast majority of blindness is avoidable. The World Health Organization (WHO) estimates that 80% of cases of visual impairment could be prevented or reversed with early diagnosis and treatment.
- Conditions
- Age-related Macular Degeneration, Diabetic Retinopathy, Glaucoma
- Trial name
- VIEW II (NCT03752840)
- Testing
- Visual acuity (presenting and pinhole), Optical coherence tomography (OCT), Intraocular pressure
- Where
- United States
- Volunteers
- 60,200 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Hypertension, Periodontitis
Evaluation of MTHFR Gene Polymorphism and Periodontal Clinical Parameters in Healthy, Hypertensive, and Periodontitis Individuals
This observational study aims to evaluate the relationship between MTHFR gene polymorphisms and periodontal clinical findings in healthy individuals, individuals with hypertension, individuals with periodontitis, and individuals…
- Trial name
- NCT07873385
- Testing
- MTHFR Gene Polymorphism Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Malaria Infection, Pregnancy
Diagnostic Access to Self-Care and Health Services in Low and Middle Income Countries (DASH) - Phase II
Our primary goal is to determine if on-demand, home-based rapid testing, or rapid testing done by a community health worker (CHW) results in people testing for diseases more frequently and getting care more quickly.
- Conditions
- Malaria Infection, Pregnancy, HIV, Diabetes
- Trial name
- DASH (NCT06588790)
- Testing
- Home-based rapid testing, Community health worker rapid testing
- Where
- 3 sites in Kenya, South Africa and 1 more
- Volunteers
- 2,250 people, healthy volunteers welcome
- Sponsor
- University of Washington
Overweight and Obesity
High Vitamin K Intake Diet Intervention Effect on Cardiovascular Risk Percentage in Young Adults
The goal of this clinical trial is to compare the effect of a high vitamin K diet intervention on vitamin K, insulin, osteocalcin serum levels and the cardiovascular risk percentage in normal weight and overweight or obese young…
- Trial name
- VKDI (NCT06250647)
- Testing
- vitamin K diet
- Where
- Mexico
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Guadalajara
Stroke
The Evaluation of Safety, Tolerability and Pharmacokinetics of Stroke Targeting Drug in Healthy Volunteers
The purpose of this study in to evaluate safety, tolerability, pharmacokinetics of JPI-289 in healthy male subjects.
- Trial name
- JPI-289 (NCT01983358)
- Testing
- JPI-289
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jeil Pharmaceutical Co., Ltd.
Obesity
Effect of a Unique Web-based Behaviour Change Program on Weight Loss and Cardiovascular Risk Factors
Web- or internet-based programs have the potential to induce and, possibly, help to sustain, significant lifestyle modification.
- Trial name
- NCT01472276
- Testing
- Web-based program
- Where
- United Kingdom
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Pulmonary Hypertension, Metal Poison
Study Roles of Heavy Metals and Essential Metal Dyshomeostasis in Pulmonary Arterial Hypertension Patients
Investigators plan to recruit 50 PAH patients from UofL PAH Clinic, with various degrees of severity (25 intermediate risk patients and 20 high risk patients) and 10 age and gender matched controls.
- Trial name
- NCT04756076
- Testing
- Metal level measurements
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Jiapeng Huang
Abdominal Aortic Aneurysm, Coronary Heart Disease
Ethnicity and Onset of Cardiovascular Disease: A CALIBER Study
Specific cardiovascular diseases, such as stroke and heart attack, have been shown to vary by ethnic group. However, less is known about differences between ethnic groups and a wider range of cardiovascular diseases.
- Conditions
- Abdominal Aortic Aneurysm, Coronary Heart Disease, Sudden Cardiac Death, Intracerebral Haemorrhage
- Trial name
- NCT02176174
- Volunteers
- 1,068,318 people, healthy volunteers welcome
- Sponsor
- University College, London
Sedentary Lifestyle, Overweight and Obesity
The Effect of Frequency and Duration of Breaks in Sitting Time on Metabolic Cardiovascular Risk Factors
The primary aim of this study is to investigate the acute effect of the frequency and duration of breaks in sitting time on the metabolic risk factor profile.
- Conditions
- Sedentary Lifestyle, Overweight and Obesity, Metabolic Disease
- Trial name
- BPS2 (NCT02951624)
- Testing
- Control, Breaker, Prolonger
- Where
- Denmark
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cardiovascular Diseases
Improved Cardiovascular Disease hEALth Service Delivery in Australia: Cluster Randomised Controlled Trial (IDEAL Study)
The IDEAL study is a randomized controlled trial among people referred to pathology services to have blood cholesterol measured. Study participants will have cardiovascular risk factors (e.g.
- Trial name
- IDEAL (NCT04896021)
- Testing
- Cardiovascular disease risk assessment, Usual care assessment
- Where
- Australia
- Volunteers
- 2,761 people, healthy volunteers welcome
- Sponsor
- Menzies Institute for Medical Research
Type 2 Diabetes Mellitus (T2DM), Cardiovascular Diseases
Bioequivalence Study to Compare Empagliflozin/Linagliptin/Metformin HCl25 mg/5 mg/1000 mg Extended Release Tablet Versus Trijardy® XR 25 mg/5 mg/1000 mg Extended- Release Tablets
An open label, randomized, two-period, two treatment, two-sequence, crossover, balanced, single dose oral bioequivalence study to compare Empagliflozin/ Linagliptin/ Metformin HCl 25 mg/5 mg/1000 mg Extended Release Tablet versus…
- Trial name
- NCT07872358
- Testing
- Empagliflozin/Linagliptin/Metformin HCl Extended Release Tablet, Trijardy® XR Tablets
- Where
- India
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Humanis Saglık Anonim Sirketi
Valvular Heart Disease
Effect of Desflurane on Cardiac Function During Cardiac Surgery: Tissue Doppler Imaging of Mitral Valve Annular Velocity
The purpose of this study is to determine desflurane's dose-dependent effect on left ventricular (LV) function in cardiac surgery.
- Trial name
- NCT02003885
- Testing
- increment of desflurane
- Where
- South Korea
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Konkuk University Medical Center
Glaucoma, Hypertension
Know Your Pressures NYC
Dr. Lisa A. Hark (PI and Study Chair) and an interdisciplinary team have designed "Know Your Pressures NYC" to conduct blood pressure (BP)/glaucoma screenings in adults age 40+ to identify undiagnosed and/or uncontrolled…
- Conditions
- Glaucoma, Hypertension, Glaucoma, Suspect, Elevated Blood Pressure
- Trial name
- NCT05992415
- Testing
- Virtual Automated Navigator Intervention with Health Education, Usual Care
- Where
- United States
- Volunteers
- 7,085 people, healthy volunteers welcome
- Sponsor
- Columbia University
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