Clinical trials: Cardiovascular Disease, Obesity
Cardiovascular Diseases, Heart Diseases
Anger and Cardiovascular Risk in Urban Youth
To examine anger and cardiovascular disease risk in urban youth. The project studied patterns of hemodynamic responses to social and nonsocial stressors, ambulatory blood pressure (BP), fasting insulin, fasting glucose, lipid…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypertension, Obesity
- Trial name
- NCT00005383
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Obesity Prevention, Heart Disease
Promoting Physical Activity and Fitness Among Underserved Latino Families Living in U.S.-Mexico Border Regions
This study has the goal to increase physical activity and fitness among Latinos in San Diego, California and Mexicali, Baja California (U.S.-Mexico border) since these cities have similar diseases such as high rates of heart…
- Trial name
- AFL (NCT06596902)
- Testing
- Physical Activity
- Where
- United States
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Cardiovascular Disease
Effects of Peanut Consumption on Postprandial Inflammation, Glucose and Triglycerides
This pilot study will investigate the effects of acute peanut consumption on markers of inflammation, triglycerides and glucose.
- Trial name
- PKEPEANUT (NCT01173042)
- Testing
- Peanuts, Glucose and whipping cream, Oil Blend
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Penn State University
Heart Failure, Diastolic, Obesity
Exercise Intolerance in Elderly Patients With HFpEF(Heart Failure With Preserved Ejection Fraction)
The purpose of this study is to examine the effects of weight loss via hypocaloric diet (CR)and aerobic exercise (AT) compared to the effects of weight loss via hypocaloric diet (CR), aerobic training (AT)and resistance training…
- Trial name
- SECRET-II (NCT02636439)
- Testing
- dietary, aerobic and resistance training, dietary, and aerobic exercise
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Wake Forest University Health Sciences
Cardiovascular Diseases, Heart Diseases
Lifestyle, Adiposity and Cardiovascular Health in Youths
To determine the influences of diet and physical activity (PA) on total body fatness and regional fat distribution and the relationship of these to risk factors of cardiovascular disease during adolescence.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Obesity
- Trial name
- NCT00006402
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Obese, Hypertension
Comparison of Aerobic, Resistance, and Combined Training in Overweight/Obese Hypertensive Adults
To compare the effects of aerobic, resistance and combined training in hypertensive obese patients
- Trial name
- NCT05061173
- Testing
- Aerobic exercise training Group, Resistance Exercise Training Group, Combined Exercise Training Group
- Where
- Pakistan
- Volunteers
- 63 people
- Sponsor
- Riphah International University
Vascular Disease, Peripheral, Physical Inactivity
Inter-individual Physiological Response to a Training and Detraining Period in Cardiometabolic Risk Factors Subjects
Background: Although exercise training is a well described therapy for some cardiometabolic diseases such as obesity, type 2 diabetes, arterial hypertension, and metabolic syndrome, there is scarcity of knowledge about the…
- Conditions
- Vascular Disease, Peripheral, Physical Inactivity, Arterial Hypertension, Endothelial Dysfunction
- Trial name
- VASCU-HEALTH (NCT05710653)
- Testing
- Exercise training intervention
- Where
- Chile
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Cristian Alvarez
Obesity & Overweight, Perimenopausal Women
Prebiotic Inulin for Late-Reproductive Individuals
This study aims to evaluate the effects of 2 weeks of inulin supplementation in perimenopausal women with overweight or obesity. The primary questions this study seeks to answer are: 1.
- Conditions
- Obesity & Overweight, Perimenopausal Women, Prebiotics, Inulin
- Trial name
- PILI (NCT07724522)
- Testing
- Inulin
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- George Washington University
Obesity, Prehypertension
Weight Inclusive and Adaptive Strategies to Enhance Cardiometabolic Health in Black Adults
The proposed 6-month pilot Sequential Multiple Assignment Randomize Trial (SMART) has two aims. The first and primary aim is to determine the feasibility of conducting a full-scale SMART to compare weight-focused (i.e., weight…
- Conditions
- Obesity, Prehypertension, Hypertension, PreDiabetes
- Trial name
- WISE Health (NCT06284681)
- Testing
- Weight-focused health coaching, Weight-neutral health coaching, Intensify lifestyle approach
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of Alabama at Birmingham
Metabolic Syndrome
Effect of Resistant Starch (Type-4) on Metabolic Syndrome
Metabolic syndrome is a condition characterized by excess body weight, large waist circumference, high cholesterol and glucose in the blood, and hypertension.
- Trial name
- NCT01887964
- Testing
- RS4 enriched flour, Control flour
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- South Dakota State University
Cardiovascular Diseases, Diabetes Mellitus
CV Disease in Adolescents With Type 2 Diabetes
To study cardiac and vascular structure and function in a population of adolescents with type 2 diabetes mellitus (T2DM) compared to a similar group with obesity alone and a similar non-obese group.
- Conditions
- Cardiovascular Diseases, Diabetes Mellitus, Heart Diseases, Obesity
- Trial name
- NCT00114998
- Where
- United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Fractures
Influence of External Factors on Skeletal Growth in Youth
Objective: Prospective study regulation in bone mass, size, architecture, cortical, trabecular bone, soft tissues and risk factors for cardiovascular disease at growth. Determine regulation by environmental factors.
- Trial name
- NCT00633828
- Testing
- Increased physical education in primary school (daily)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Region Skane
Metabolic Disease, Obesity
Adiposity, Cardiometabolic and Neurocognitive Health Among Ethnic Groups: a Feasibility and Pilot Study
The goal of this pilot and feasibility study is to is to test the feasibility of conducting a cross-sectional study on adiposity and cardiometabolic and neurocognitive risk factors at Kings College Hospital NHS Foundation Trust…
- Conditions
- Metabolic Disease, Obesity, Hepatic Steato-Fibrosis, Cardiovascular Diseases
- Trial name
- ACNH (NCT06435611)
- Where
- 2 sites in United Kingdom
- Volunteers
- 10 people
- Sponsor
- King's College Hospital NHS Trust
Overweight and Obesity
An Acceptance-Based Healthy Lifestyle Intervention for Diverse Adolescents
The goal of this clinical trial is to learn about cardiovascular disease risk among adolescent girls with overweight/obesity. The main questions this trial aims to answer are: 1.
- Trial name
- NCT06147973
- Testing
- Acceptance-based Treatment (ABT), Health Education (HE) Comparison
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Obesity, Cardiovascular Diseases
High-intensity Exercise Training or Multidisciplinary Treatment in Extremely Obese Adolescents
The aim of the present study was to determine the effects of a multidisciplinary approach and intensity-controlled interval training on cardiovascular risk factors in overweight adolescents
- Trial name
- NCT00682266
- Testing
- intensity controlled interval training (AIT), Multidisciplinary approach (MTG)
- Where
- Norway
- Volunteers
- 54 people
- Sponsor
- Norwegian University of Science and Technology
Overweight and Obesity, Dyslipidemias
Reducing Circulating Sphingolipid Levels to Optimise Cardiometabolic Health - The SphingoFIT Trial
The purpose of this study is to assess the effects of an 8-week supervised high-intensity interval training (HIIT) program (vs. physical activity recommendations according to current guidelines) on a comprehensive panel of…
- Conditions
- Overweight and Obesity, Dyslipidemias, Blood Pressure, Cardiovascular Diseases
- Trial name
- SphingoFIT (NCT06024291)
- Testing
- 8-week HIIT programme, Physical activity recommendation
- Where
- Switzerland
- Volunteers
- 88 people
- Sponsor
- University of Basel
Left Ventricular Dysfunction, Myocardial Infarction
St. Vincent's Screening To Prevent Heart Failure Study
The STOP-HF study is a prospective, randomized, controlled trial recruiting asymptomatic individuals with risk factors for left ventricular dysfunction from 50 primary care clinics in Dublin and south east Ireland.
- Conditions
- Left Ventricular Dysfunction, Myocardial Infarction, Hypertension, Diabetes
- Trial name
- STOP-HF (NCT00921960)
- Testing
- Intervention Care
- Where
- Ireland
- Volunteers
- 1,378 people
- Sponsor
- St Vincent's University Hospital, Ireland
Hypertension, Insulin Resistance
A Comparison of the Effect of Olmesartan Medoxomil, Losartan Potassium, and Atenolol on the Ability of Overweight Patients With High Blood Pressure to Respond to Insulin
To examine the effect of three different blood pressure medications on the insulin sensitivity in overweight patients with high blood pressure.
- Conditions
- Hypertension, Insulin Resistance, Metabolic Syndrome
- Trial name
- NCT00185094
- Testing
- Olmesartan medoxomil, Losartan potassium, Atenolol
- Where
- 10 sites in United States
- Volunteers
- 60 people
- Sponsor
- Daiichi Sankyo
Cardiovascular Diseases, Heart Diseases
Weight Set-Point and HDL Concentration in Runners
To investigate the differences in diet, fat cell morphology and lipoprotein metabolism in previously- overweight and naturally lean men and women who ran and who lived sedentary lifestyles in order to better understand the…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Obesity
- Trial name
- NCT00005342
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Diabetes Mellitus, Type 2, Cardiovascular Diseases
Variation of Genes Controlling Carbohydrate and Lipid Metabolism
Aim of the study is to investigate genes regulating glucose and lipid metabolism in subjects whose glucose metabolism, lipid metabolism, blood flow, or body fat distribution has been measured using positron emission tomography…
- Conditions
- Diabetes Mellitus, Type 2, Cardiovascular Diseases, Obesity, Insulin Resistance
- Trial name
- CMgene (NCT03310502)
- Where
- Finland
- Volunteers
- 2,050 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.