Clinical trials: Cardiovascular Disease, Obesity
NAFLD, NASH
The European NAFLD Registry
The European NAFLD Registry is a prospectively recruited, observational study supporting the study of the clinical phenotype, natural history, disease outcomes and pathophysiology of Non-Alcoholic Fatty Liver Disease and…
- Conditions
- NAFLD, NASH, NASH - Nonalcoholic Steatohepatitis, Fibrosis, Liver
- Trial name
- NCT04442334
- Where
- 37 sites in Belgium, Finland and 10 more
- Volunteers
- 10,000 people
- Sponsor
- Newcastle University
Cardiovascular Disease, Hypertension
The GoodNEWS Lifestyle Enhancement Program
This study will train Lay Health Promoters (LHPs) from African-American churches to administer healthy living lessons and activities to their congregations in order to improve overall health and address cardiovascular disease.
- Conditions
- Cardiovascular Disease, Hypertension, Diabetes, Obesity
- Trial name
- GoodNEWS (NCT00669630)
- Testing
- Lay Health Promoter (LHP) with maintenance
- Where
- United States
- Volunteers
- 392 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Metabolic Syndrome, Dyslipidemias
12 Weeks of Resistance Band Exercise Impacts on Metabolic Syndrome Progression in Postmenopausal Women
The purpose of this study was to examine the impacts of a 12-week resistance band exercise program on insulin resistance, blood lipid profiles, body composition, and blood pressure in postmenopausal women with obesity.
- Conditions
- Metabolic Syndrome, Dyslipidemias, Insulin Resistance, Hypertension
- Trial name
- NCT04014686
- Testing
- No exercise intervention group, Resistance band exercise intervention group
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Pusan National University
Hypertension, Hypertension (HTN)
FIM+DASH: Food is Medicine Intervention to Promote Healthy Eating and Blood Pressure Control
The goal of this clinical trial is to treat both hypertension and obesity in adults using a food is medicine framework. Participants will be randomized 1:1 to FIM+DASH or usual-care control.
- Conditions
- Hypertension, Hypertension (HTN), Obesity & Overweight
- Trial name
- FIM+DASH (NCT07332741)
- Testing
- FIM intervention arm, FIM Usual Care Arm
- Where
- 4 sites in United States
- Volunteers
- 150 people
- Sponsor
- University of Illinois Chicago
Obesity, Cardiovascular Diseases
Motivation Makes the Move!
This study evaluates the effect and usability of mobile and cloud technology -based intervention on lifestyle modification in 18-40 year obese and overweight subjects.
- Conditions
- Obesity, Cardiovascular Diseases, Physical Conditioning
- Trial name
- MoMaMo! (NCT02686502)
- Testing
- Lifestyle
- Where
- 2 sites in Finland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Obesity &Amp; Overweight, Hypertension
A Prospective Randomnised Controlled Trial Comparing Overall Patient Compliance in a Bariatric Surgical Pathway Using the Standard Versus a More Intensified and Interactive Version of the "Get Ready" Smartphone Application.
The aim of this study is to assess the impact of a newly intensified digital platform following bariatric surgery. This will be measured using several questionnaires.
- Conditions
- Obesity &Amp; Overweight, Hypertension, Obstructive Sleep Apnea (OSAS), Diabetes Mellitus ( Type 1 and Type 2)
- Trial name
- NCT07297342
- Testing
- GetReady application, Intensified GetReady application
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Sint Dimpna Ziekenhuis Geel
Cardiovascular Risk Factor, Cardiovascular Diseases
Umbrella Review of the DASH Dietary Pattern and Cardiometabolic Risk
The European Association for the Study of Diabetes (EASD) guidelines have not made any specific recommendations regarding the Dietary Approaches to Stop Hypertension (DASH) diet, a dietary pattern that emphasizes fruits and…
- Conditions
- Cardiovascular Risk Factor, Cardiovascular Diseases, Coronary Heart Disease, Stroke
- Trial name
- NCT03542370
- Testing
- DASH dietary pattern
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- University of Toronto
Obesity, Overweight
Vitamin D Supplementation for the Prevention of Cardiovascular Risk
Hypovitaminosis D is highly prevalent in the general population, particularly in obese individuals. Besides being associated with obesity, vitamin D deficiency seems to be involved in the pathogenesis of insulin resistance and…
- Conditions
- Obesity, Overweight, Insulin Resistance
- Trial name
- NCT02020694
- Testing
- Vitamin D
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Obesity & Overweight, Adult Congenital Heart Disease
Effect of Tirzepatide on Cardiovascular and Metabolic Parameters in Obese Adult Patients With Congenital Heart Disease
Several drugs have been shown effective in the treatment of obesity, with concomitant favourable cardiovascular effects. Today, there are no studies on novel anti-obesity drugs in patients with adult congenital heart disease…
- Trial name
- TEACH (NCT07354880)
- Testing
- Treatment with tirzapatide
- Volunteers
- 30 people
- Sponsor
- University Medical Centre Ljubljana
Atrial Fibrillation (AF), Obesity (Disorder)
Improving Outcomes After AF Ablation in Obese Patients
Improving Outcomes After AF Ablation in Obese Patients
- Trial name
- OBESE-AF (NCT07618741)
- Testing
- Cardiac Rehabilitation and Lifestyle Modification, Usual Care
- Where
- Taiwan
- Volunteers
- 520 people
- Sponsor
- National Taiwan University Hospital
Cardiovascular Diseases, Obesity
School-Based Intervention to Increase Physical Activity Among Adolescent Females
Physical inactivity is a major public health problem in the United States. Research has shown that physical activity levels decline during adolescence, and the decline is greater in females than males.
- Trial name
- NCT00296101
- Testing
- Physical Activity
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Obesity, Metabolic Syndrome X
Exercise Training and Hepatic Metabolism in Overweight/Obese Adolescent
The HEPAFIT Study aims to examine whether a 6-months physical education program has benefits on hepatic metabolism and cardiovascular health as well as on selected physical fitness and mental health outcomes among adolescent…
- Conditions
- Obesity, Metabolic Syndrome X, Lipid Metabolism Disorders, Body Composition, Beneficial
- Trial name
- HEPAFIT (NCT02753231)
- Testing
- Low physical activity program, High physical activity program, Low and High physical activity program
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universidad Santo Tomas
Obesity, Bariatric Surgery Candidate
Preoperative Use of a Magnetically Controlled Capsule Endoscopy in Patients Undergoing Bariatric Surgery
The goal of this clinical trial is to test if a swallowable camera capsule can safely examine the upper digestive tract in people preparing for weight loss surgery.
- Conditions
- Obesity, Bariatric Surgery Candidate, Hypertension, Diabetes
- Trial name
- NAVICAM (NCT07587437)
- Testing
- Magnetically Controlled Capsule Endoscopy (MCCE)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Jerry Dang
Obesity, Diabetes Mellitus, Type 2
A Study of the Safety and Efficacy of Topiramate in the Treatment of Obese, Type 2 Diabetes Patients on a Controlled Diet
The purpose of this study is to determine the efficacy and safety of topiramate compared with placebo in obese, Type 2 diabetic patients on a controlled diet.
- Conditions
- Obesity, Diabetes Mellitus, Type 2, Diabetes Mellitus, Adult-Onset
- Trial name
- NCT00231530
- Testing
- topiramate
- Volunteers
- 541 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Natriuretic Peptides, Cardiovascular Diseases
CARBON: UAB Cardiovascular Research Biobank
The UAB Cardiovascular Research Biobank (CARBON) will be a resource that contains biological materials, such as DNA samples, in addition to health and personal information on a large number of people over time.
- Conditions
- Natriuretic Peptides, Cardiovascular Diseases, Hypertension, Diabetes
- Trial name
- CARBON (NCT05067231)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Obesity
BLOSSOM: Behavioral Modification and Lorcaserin Second Study for Obesity Management
The purpose of this study is to assess the weight loss effect of lorcaserin during and at the end of 1 year of treatment in overweight and obese patients.
- Trial name
- NCT00603902
- Testing
- Lorcaserin 10 mg once daily (QD), Lorcaserin 10 mg twice a day (BID)
- Where
- United States
- Volunteers
- 4,008 people
- Sponsor
- Eisai Inc.
Overweight , Obesity
Two-Week Stair-Climbing Exercise Snacks and Metabolic Health in Adults With Overweight or Obesity: A Pilot Study
This pilot study will evaluate whether brief bouts of stair climbing performed throughout the day for two weeks can improve metabolic health, cardiovascular fitness, and other health-related outcomes in adults with overweight or…
- Trial name
- NCT07849439
- Testing
- Stair-Climbing Exercise Snacks
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Obesity, Heart Failure
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
This study is being done to look at the safety and effect of NNC0487-0111 in people with Heart Failure with preserved Ejection Fraction (HFpEF) or Heart Failure with mildly reduced Ejection Fraction (HFmrEF) and excess body…
- Trial name
- HF-POLARIS (NCT07567001)
- Testing
- NNC0487-0111
- Where
- 838 sites in United States, Argentina and 25 more
- Volunteers
- 5,610 people
- Sponsor
- Novo Nordisk A/S
Obesity, Hypertension
The Effects of Metformin on Blood Vessel Structure and Function
The purpose of this study is to evaluate whether the drug Metformin has beneficial effects on the blood vessels of individuals with the Metabolic Syndrome (MeS).
- Conditions
- Obesity, Hypertension, Hypercholesterolemia, Hyperglycemia
- Trial name
- NCT00105066
- Testing
- Metformin
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- National Institute on Aging (NIA)
Ischemic Stroke
Ischemic Stroke, Obesity and Thrombolysis
This study focuses on the relationship between obesity and stroke, which are both characterized by increasing incidence and prevalence with epidemic proportions worldwide and tremendous socio-economic consequences.
- Trial name
- ISOT (NCT04196894)
- Where
- 2 sites in Switzerland
- Volunteers
- 280 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.