Clinical trials: Cardiovascular Disease, Obesity
Metabolic Syndrome
Effect of Resistant Starch (Type-4) on Metabolic Syndrome
Metabolic syndrome is a condition characterized by excess body weight, large waist circumference, high cholesterol and glucose in the blood, and hypertension.
- Trial name
- NCT01887964
- Testing
- RS4 enriched flour, Control flour
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- South Dakota State University
Heart Diseases
Identifying Genes That May Increase the Risk for Heart Disease in African Americans
Heart disease and stroke disproportionately affect African Americans in the United States. These conditions are likely caused by both environmental and genetic factors.
- Trial name
- NCT00344136
- Where
- United States
- Volunteers
- 5,302 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Diabetes Mellitus, Type 2, Cardiovascular Diseases
Active Communities - Adherence to Physical Activity
The primary aim of this study is to investigate whether a number of co-created bridge-building activities between municipality-based lifestyle programs and community-based physical activities (e.g.
- Conditions
- Diabetes Mellitus, Type 2, Cardiovascular Diseases, Obese
- Trial name
- NCT05493345
- Testing
- Bridge-building between municipality-based lifestyle programs and community-based physical activities
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Obesity, Hypertension
Cardiovascular Effects of Angiotensin-(1-7) in Obesity Hypertension
Obesity is a global health concern that is associated with high blood pressure and an increased risk for developing cardiovascular disease.
- Trial name
- NCT06482853
- Testing
- Angiotensin-(1-7), Saline
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Milton S. Hershey Medical Center
Aging, Menopause
Gonadal Hormone, Gonadotropin and Cardiovascular Events
Deficiency in gonadal hormone has been considered to play a role in ageing related increased incidence of cardiovascular events. But the mechanism has not been fully elucidated.
- Trial name
- NCT02810821
- Where
- China
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Shandong Provincial Hospital
Hypertension
Safety and Efficacy Study of BMS-823778 to Treat Uncontrolled High Blood Pressure in Overweight and Obese Patients
The purpose of this study is to determine whether BMS-823778 is safe and effective in the treatment of hypertension in overweight and obese patients.
- Trial name
- NCT01602367
- Testing
- BMS-823778
- Where
- 35 sites in United States, Colombia and 3 more
- Volunteers
- 7 people
- Sponsor
- Bristol-Myers Squibb
Cardiovascular Risk Factor
SEMEiotic Oriented Technology for Individual's CardiOmetabolic Risk Self- assessmeNt and Self-monitoring
Cardio-metabolic risk factors include obesity, physical inactivity, smoke, alcohol abuse, high blood lipids or sugar and arterial hypertension.
- Trial name
- SEMEOTICONS (NCT02818504)
- Testing
- Wize Mirror
- Where
- 3 sites in France, Italy
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Istituto di Fisiologia Clinica CNR
Cardiovascular Diseases, Heart Diseases
Trial of Activity for Adolescent Girls (TAAG)
To test the effectiveness of a multicomponent school-based and community-linked intervention in preventing the decline in physical activity levels and cardiovascular fitness in girls in grades 6-8.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Obesity
- Trial name
- TAAG (NCT00006409)
- Testing
- Trial of Activity for Adolescent Girls (TAAG)
- Volunteers
- 8,727 people
- Sponsor
- University of North Carolina, Chapel Hill
Obesity (Disorder), Diabetes Type 2
Healthy Living Anson Study
The goal of this randomized delayed control intervention research study is to see if participants who receive education and healthy prepared meals improve the quality of their diet compared to participants who receive only…
- Conditions
- Obesity (Disorder), Diabetes Type 2, Heart Disease, Hypertension
- Trial name
- HLA (NCT07126587)
- Testing
- Nutrition Education and Food Delivery, Physical Activity Comparator
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Prostate Cancer, Metabolic Syndrome
Akkermansia Muciniphilia and Metabolic Side Effects of ADT
The overriding objectives of this study are: 1. Primary outcomes: 1. To confirm that administration of oral acetate increases the proportion of A.
- Conditions
- Prostate Cancer, Metabolic Syndrome, Obesity, Cardiovascular Morbidity
- Trial name
- NCT05802121
- Testing
- Apple Cider Vinegar
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Western University
Obesity, Metabolic Syndrome
Weight Loss and Changes in Cardiovascular Risk Markers With a Low Glycemic Diet Compared With a Standard Diet
Overweight and obesity is increasing in most countries, including Norway, and the optimal diet for reducing weight is under discussion.
- Trial name
- NCT00230919
- Testing
- Diet counseling
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- Ullevaal University Hospital
Cardiovascular Disease
Gender, Obesity, C-Reactive Protein, and Oxidative Stress
This randomized placebo-controlled trial will test whether supplementing with vitamins C and E can lower markers of inflammation and oxidative stress in healthy adults.
- Trial name
- NCT00079963
- Testing
- Vitamin C, Vitamin E
- Where
- United States
- Volunteers
- 396 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Metabolic Syndrome, Obesity
Prevention of the Metabolic Syndrome by New Lifestyle Intervention Methods
This intervention aims to reduce obesity by using new type of nutritional and lifestyle therapy and in parallel, tailored persuasive information and communications technology (ICT)-technology based application.
- Conditions
- Metabolic Syndrome, Obesity, Overweight, Cardiovascular Disease
- Trial name
- PrevMetSyn (NCT01959763)
- Testing
- Weight loss counseling program
- Where
- Finland
- Volunteers
- 574 people
- Sponsor
- University of Oulu
Obesity, Hypertension
Tongzhou Cohort Study
Long-term Impact of Overweight/Obesity and Hypertension on Cardiovascular Risk in Middle-aged and Elderly Adults
- Trial name
- NCT05156580
- Testing
- No intervention
- Where
- China
- Volunteers
- 31,080 people, healthy volunteers welcome
- Sponsor
- Beijing Friendship Hospital
Osteoarthritis Pain, Myocardial Infarction (MI)
Community Physical Exercise Program in Chronic Disease
This study focuses on promoting physical activity (PA) through the implementation of a Community Physical Exercise Program for Chronic Diseases (CPEP-CD), targeting individuals aged 50 years and older with at least two of the…
- Conditions
- Osteoarthritis Pain, Myocardial Infarction (MI), Hypertension, Dyslipidemia
- Trial name
- CPEPCD (NCT06771024)
- Testing
- Physical Exercise
- Where
- Portugal
- Volunteers
- 150 people
- Sponsor
- Associação para o Desenvolvimento do Centro Académico de Investigação e Formação Biomédica do Algarv
Hypertension, Obesity
A Randomized, Double-Blind, Active Control Trial Comparing Effects of Telmisartan, Candesartan and Amlodipine, Alone or Plus Metformin, on Non-Diabetic, Obese Hypertensive Patients
The epidemic of obesity is associated with a considerable rise in the incidence of the metabolic syndrome, type 2 diabetes mellitus, and hypertension.
- Trial name
- HOT-ACME (NCT00538486)
- Testing
- Telmisartan plus Metformin, Telmisartan, Candesartan
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Third Military Medical University
Obesity
Nighttime Macronutrient Choice and Combined Resistance and High-intensity Interval Training
Obesity is recognized as a major public health concern because of its link to potential fatal complications arising from metabolic and cardiovascular diseases.
- Trial name
- NCT01830946
- Testing
- Whey Protein, Combined Resistance and High-Intensity Interval training, Casein Protein
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Florida State University
Cardiovascular Diseases, Diabetes Mellitus
Retrospective Evaluation of Athens Complete Health Improvement Program (CHIP) Database
Data from participants in Athens CHIP classes from May 2011 to present will be analyzed to evaluate the differences in outcomes based on: 1) gender, 2) age, 3) whether a household member participated in the class with them.
- Conditions
- Cardiovascular Diseases, Diabetes Mellitus, Hypertension, Dyslipidemias
- Trial name
- NCT03025451
- Testing
- The Complete Health Improvement Program
- Where
- United States
- Volunteers
- 512 people, healthy volunteers welcome
- Sponsor
- Ohio University
Obesity, Pre-hypertension
The Effects of Stretching Training on Arterial Function and Autonomic Control
Hypertension is a major risk factor for cardiovascular disease. Hypertension and abdominal obesity are associated with dysfunction of the main mechanisms of cardiovascular regulation, the autonomic nervous system and the vascular…
- Conditions
- Obesity, Pre-hypertension, Hypertension
- Trial name
- NCT01741766
- Testing
- Stretching Training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Florida State University
Hypertension
International Multicenter, Observational, Non-Interventional Prospective Study of Azilsartan Medoxomil in Participants With Arterial Hypertension Who Are Overweight or Obese in the Russian Federation and The Republic of Kazakhstan
The purpose of this study is to estimate antihypertensive effect of azilsartan medoxomil (Edarbi®) therapy on blood pressure in participants with overweight or obesity in routine clinical practice of hypertension (HTN) treatment…
- Trial name
- NCT02756819
- Testing
- Azilsartan Medoxomil
- Where
- 66 sites in Kazakhstan, Russia
- Volunteers
- 1,945 people
- Sponsor
- Takeda
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