Clinical trials: Cardiovascular Disease Risk Factors
Cervical Artery Dissection, Stroke
Looking For Genetic and Environmental Risk Factors and Therapeutic Aspects in Cervical Artery Dissections
The main purpose of this study is to look for genetic and environmental risk factors of cervical artery dissections, a major cause of ischemic stroke in young adults, in a large multicenter case-control trial
- Conditions
- Cervical Artery Dissection, Stroke, Brain Infarction
- Trial name
- CADISP (NCT00657969)
- Where
- 24 sites in Argentina, Belgium and 7 more
- Volunteers
- 4,169 people
- Sponsor
- Cervical Artery Dissections and Ischemic Stroke Patients - Consortium
Ischemic Stroke, Transient Ischemic Attack
Empowerment and Mobile Technology in the Control of Cardiovascular Risk Factors in Patients With Ischemic Stroke
The CARDIOSTROKE is a randomized trial comparing mobile-device assisted control of hypertension together with screening of occult atrial fibrillation to standard care in patients with recent ischemic stroke or transient ischemic…
- Conditions
- Ischemic Stroke, Transient Ischemic Attack, Atrial Fibrillation, Hypertension
- Trial name
- CARDIOSTROKE (NCT03710902)
- Testing
- ECG monitoring for 3 weeks, Self-monitoring of BP and self-titration of antihypertensive medication
- Where
- 4 sites in Finland
- Volunteers
- 405 people
- Sponsor
- Jukka Putaala
Cardiovascular Diseases, Cardiovascular Risk Factor
The Effect of Endothelin and L-Arginine on Racial Differences in Vasoconstriction
The goal of the study is to examine the possible mechanisms of impaired cutaneous microvascular function through local heating along with administration of vasoconstrictors.
- Conditions
- Cardiovascular Diseases, Cardiovascular Risk Factor, Vasoconstriction
- Trial name
- NCT03679780
- Testing
- BQ-788, BQ-123, L-Arginine
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Extracorporeal Membrane Oxygenation Complication, Hemorrhage
Platelets and Extracorporeal Membrane Oxygenation Veno-venous
In severe lung or heart disease, ExtraCorporeal Membrane Oxygenation (ECMO) may be used temporarily and can be responsible for major haemorrhagic complications. Thrombocytopenia and possibly thrombopathy promote bleeding.
- Conditions
- Extracorporeal Membrane Oxygenation Complication, Hemorrhage, Blood Platelet Disorder, Thrombosis
- Trial name
- PLAT-VV-ECMO (NCT07580469)
- Testing
- blood draws
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Toulouse
Inflammatory Arthritis, Cardiovascular Risk Factor
Pharmacist CVD Intervention for Patients With Inflammatory Arthritis
Cardiovascular disease (CVD) (disease of the heart and blood vessels) is one of the leading causes of death and disability in Canada today. The majority of CVD cases are caused by factors that can be controlled.
- Conditions
- Inflammatory Arthritis, Cardiovascular Risk Factor, Rheumatoid Arthritis, Ankylosing Spondylitis
- Trial name
- RxIALTA (NCT03152396)
- Testing
- CV risk assessment and modification of global risk
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Epidemiology Coordinating and Research Centre, Canada
Coronary Artery Disease, Non-Obstructive Coronary Atherosclerosis
VIsualization of Coronary Artery Disease for Modification of RISK Factors
The VICAD-RISK study assesses if visualization of coronary CT angiography (CTA) images in participants with non-obstructive coronary artery disease will improve LDL lowering, reduce reporting of side effects by cholesterol…
- Trial name
- VICAD-RISK (NCT06413641)
- Testing
- Follow up at general practice, Consultation, Visualization of CTA images
- Where
- 5 sites in Denmark
- Volunteers
- 273 people
- Sponsor
- Aarhus University Hospital
Cardiovascular Disease Risk Factors
Reducing CVD Risk in African Americans Faith Communities
The ultimate goal of our partnership with local African-American churches is to implement an effective, multi-component intervention to increase awareness of the critical importance of healthy lifestyle in the prevention of…
- Trial name
- FAITH! (NCT02235896)
- Testing
- Education/Behavior Modification
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Cardiac Disease, Dental Caries
Saliva Profiles in Children With Congenital Heart Disease
The purpose of this study was to evaluate whether there are relationships between the salivary oxidative stress status of children with CHD directly dental caries including gender, age, salivary flow rate, salivary pH, salivary…
- Trial name
- NCT03457974
- Testing
- saliva
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Coronary Artery Disease, Atherosclerosis
Evaluation of Asymptomatic Coronary Atherosclerotic Disease Among People of Kalamazoo, MI
The primary goal of this study is to determine the prevalence of undiagnosed asymptomatic coronary artery disease (CAD) in Kalamazoo and its neighboring areas using Coronary Computed Tomography (CCTA) and Coronary Artery Calcium…
- Trial name
- ESCAPE MI (NCT02942342)
- Testing
- Computed Tomography (CT) Scan
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Borgess Research Institute
Cardiovascular Disease
Cardiovascular and Renal Risk in Spain
IBERICAN is a multicenter, longitudinal and observational population-based study of patients daily attended in Primary Care setting in Spain.
- Trial name
- IBERICAN (NCT02261441)
- Testing
- Observational and noninterventional study
- Where
- Spain
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- La Sociedad Española de Médicos de Atención Primaria
Rheumatoid Arthritis
A Study of Tocilizumab in Comparison to Etanercept in Participants With Rheumatoid Arthritis and Cardiovascular Disease Risk Factors
This randomized, open-label, parallel-group, multicenter study will evaluate the rate of cardiovascular events with tocilizumab in comparison to etanercept in participants with rheumatoid arthritis (RA).
- Trial name
- NCT01331837
- Testing
- Etanercept, Tocilizumab
- Where
- 428 sites in United States, Argentina and 29 more
- Volunteers
- 3,080 people
- Sponsor
- Hoffmann-La Roche
Inflammation, Cardiovascular Diseases
Role of Cherry Consumption in Reducing Risk Factors for Chronic Inflammatory Diseases
The goal of this study is to examine if chronic cherry consumption will decrease lipid peroxidation and serum concentration of inflammatory markers in human subjects with elevated serum C reactive protein (CRP), and to examine…
- Trial name
- NCT01734070
- Testing
- Cherry consumption
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
COVID-19
Effectiveness of mRNA-1273 Variant-Containing Vaccine Formulation Against Severe Outcomes in Adults Aged 50-64 Years Without Risk Factors for Severe COVID-19
The purpose of this pragmatic randomized trial is to evaluate the vaccine effectiveness of the COVID-19 vaccine, mRNA-1273, in adults aged 50-64 years without known risk factors for severe COVID-19 infection.
- Trial name
- DAN-COVID (NCT07279766)
- Testing
- mRNA-1273 (Moderna COVID-19 vaccine)
- Where
- 2 sites in Denmark
- Volunteers
- 41,060 people, healthy volunteers welcome
- Sponsor
- Tor Biering-Sørensen
Diabetes Mellitus (DM), Dyslipidemia
Impact of Golden Rice-Piper Crocatum Cookies on Lipid Control in Diabetes Mellitus Patients
People with diabetes often experience abnormal blood fat levels, known as dyslipidemia, which increase the risk of heart disease and stroke.
- Conditions
- Diabetes Mellitus (DM), Dyslipidemia, Lipid Profile, Functional Food
- Trial name
- GRPC-DM (NCT07268781)
- Testing
- Golden Rice cookies with Piper crocatum Extract
- Where
- 2 sites in Indonesia
- Volunteers
- 102 people
- Sponsor
- Hasanuddin University
Schizophrenia, Cardiovascular Risk Factor
Effectiveness of a Cardiovascular Risk Intervention Program in Patients With Schizophrenia (PRISCA)
The main objective is to determine the effectiveness of a program which consists of multidisciplinary, intensive and individualized interventions, carried out by a group of health professionals (psychiatrist, psychologist, mental…
- Trial name
- PRISCA (NCT04276012)
- Testing
- Multifactorial intervention
- Where
- Spain
- Volunteers
- 130 people
- Sponsor
- Dr. Pere Roura-Poch
Hypertension, Cardiovascular Diseases
Cardiovascular Disease Risk Factors in Chinese American Immigrants
The Chinese population is currently the fastest growing ethnic group in New York City (NYC). Research has shown that Chinese immigrants living in NYC have higher rates of cardiovascular disease (CVD) than individuals in China.
- Conditions
- Hypertension, Cardiovascular Diseases, Diabetes Mellitus, Metabolic Syndrome X
- Trial name
- CHA-CHA (NCT00362128)
- Where
- United States
- Volunteers
- 2,072 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Hypertension, Diabetes Mellitus
Community Based Multiple Risk Factors Intervention Strategy
Randomized controlled trial of CORFIS Programme. The study objectives are as follows: 1. To determine the efficacy of a community based multiple risk factors interventional strategy (CORFIS) for a treatment period of 6 months in…
- Conditions
- Hypertension, Diabetes Mellitus, Hyperlipidemia
- Trial name
- CORFIS (NCT00490672)
- Testing
- No Active Intervention., Community Based Multiple Risk Factor Intervention Strategies
- Where
- 78 sites in Malaysia
- Volunteers
- 770 people
- Sponsor
- Ministry of Health, Malaysia
Acute Coronary Syndrome, Atherosclerosis
Protocol for The Lipid Registry of Africa
The Lipid Registry of Africa (LIPRA) aims to understand why some individuals in Africa experience heart issues at a younger age than others.
- Trial name
- NCT06238375
- Volunteers
- 4,000 people
- Sponsor
- European Atherosclerosis Society
Weight Maintenance, Weight Loss
The SCULPT-Job Cohort Study
This is an research study about clinical, psychosocial, and behavioral factors that impact weight loss, weight maintenance, and cardiovascular disease in socially disadvantaged persons.
- Conditions
- Weight Maintenance, Weight Loss, Stress, Psychological, Job Stress
- Trial name
- SCULPT-Job (NCT06965075)
- Testing
- Diabetes Prevention Program
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of California, San Francisco
Stroke
Vitamin D and Stroke
Stroke remains one of the most devastating neurological diseases, often causing death, or gross physical impairment. It is the second most common cause of death worldwide and a major cause of acquired disability in adults.Vitamin…
- Trial name
- NCT02916030
- Testing
- Vit D
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
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