Clinical trials: Cardiovascular Disease Risk Factors
Cardiovascular Diseases, Diabetes Mellitus, Type 2
The Japan Diabetes Optimal Integrated Treatment Study for 3 Major Risk Factors of Cardiovascular Diseases
(Intervention study) The objective of the study is to confirm the superiority of the intensive therapy to the conventional therapy concerning the prevention of the incidence or exacerbation of vascular complications caused by…
- Trial name
- J-DOIT3 (NCT00300976)
- Testing
- Lifestyle consultation: weight control, diet, exercise
- Where
- Japan
- Volunteers
- 2,542 people
- Sponsor
- Japan Foundation for the Promotion of International Medical Research Cooperation
Polycystic Ovary Syndrome
Empagliflozin vs Metformin in PCOS
This a randomised open-label parallel study involving women with polycystic ovary syndrome (PCOS). The patients will be randomised either to metformin 1500mg or empagliflozin 25mg daily for three months.
- Trial name
- NCT03008551
- Testing
- Empagliflozin, Metformin
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Postmenopausal Disorder
Physical Activity in Postmenopausal Women
The study is designed to investigate the physical activity and its dose-response relationship in postmenopausal women on the cardiovascular risks and cardiac function.
- Trial name
- NCT01398605
- Testing
- Exercise training
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Chronic Kidney Diseases, Cardiovascular Risk Factors
Cardiovascular Risk Factors and Physical Activity in Chronic Kidney Patients on Peritoneal Dialysis
The objective of this study was to examine the association between cardiovascular risk factors and physical activity parameters in patients with chronic kidney disease who are treated with peritoneal dialysis.
- Conditions
- Chronic Kidney Diseases, Cardiovascular Risk Factors, Arterial Stiffness, Physical Activity
- Trial name
- NCT07041554
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people
- Sponsor
- Dokuz Eylul University
Impotence
Improvement of Erectile Dysfunction by Fluvastatin in Patients With Cardiovascular Risk Factors
The purpose of the study is to determine the effect of fluvastatin on penile arterial blood flow and erectile function in patients with arteriogenic ED and cardiovascular risk factors.
- Trial name
- NCT00382161
- Testing
- Fluvastatin-sodium
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital, Saarland
Sodium Excess, Cardiovascular Risk Factor
A Short, Animated Storytelling Video to Increase Knowledge About Sodium Intake as a Cardiovascular Risk Factor
This study will evaluate the effect of a short, animated storytelling intervention video on sodium intake as a major risk factor for cardiovascular disease on immediate and medium-term retention of knowledge about the risks of…
- Conditions
- Sodium Excess, Cardiovascular Risk Factor, Education Entertainment Intervention, Short, Animated Storytelling
- Trial name
- NCT05735457
- Testing
- A short, animated storytelling video on dietary sodium
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- University Hospital Freiburg
Metabolic Syndrome, Cardiovascular Diseases
Tart Cherry, Metabolic Syndrome, and Cardiovascular Risk
The hypothesis of this study is that the daily consumption of 480 ml tart cherry juice for twelve weeks will improve blood pressure and arterial stiffness by improving endothelial-mediated vasodilation and vascular sympathetic…
- Conditions
- Metabolic Syndrome, Cardiovascular Diseases, Diabetes
- Trial name
- NCT02154100
- Testing
- Tart Cherry
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Florida State University
Chronic Kidney Disease
Evaluation of Cardiovascular Risk Factors in Incident Dialysis Patients
To evaluate the relationships between bone mineral markers levels at dialysis start and vascular calcification progression during a 2 year follow up
- Trial name
- NCT02813642
- Testing
- Plasma osteoprotegerin level, Plasma fibroblast growth factor 23 level, Vascular calcification score
- Where
- 5 sites in France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Montpellier
Cardiovascular Risk Factor, Lipaemia
Effect of Lactose on Blood Lipids
This study aims to determine to what extent ingestion of free sugars influence postprandial triglyceridaemia in men and women.
- Conditions
- Cardiovascular Risk Factor, Lipaemia, Metabolic Disease
- Trial name
- NCT04924530
- Testing
- Maltodextrin, Sucrose, Lactose
- Where
- United Kingdom
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Bath
Cardiovascular Risk Factor, Cardiovascular Diseases
The Role of a Motion Sensor With Accompanying Web Application on Step Counts, Energy Balance, and Metabolic Markers in Nurses
The purpose of this prospective randomized controlled trial is to explore the role of a motion sensor with accompany web application on step counts, energy balance, and metabolic markers in nurses.
- Trial name
- WALK (NCT04524572)
- Testing
- Motion sensor
- Where
- Canada
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Ottawa Heart Institute Research Corporation
Growth Hormone Deficiency
Differential Effects of rhGH vs. rhIGF-1 on Cardiovascular Risk Factors
The purpose of this study is to see if giving growth hormone or insulin-like growth factor-1 (IGF-1) to subjects with growth hormone deficiency effects cardiovascular risk factors differently.
- Trial name
- NCT00684957
- Testing
- Recombinant Human Growth Hormone, Recombinant Human IGF-1
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Columbia University
Acute Kidney Injury, Cardiogenic Shock
Acute Kidney Injury in Adult Patients Supported by VA-ECMO
Post-cardiotomy cardiogenic shock (PCCS) occurs in 2-6% of patients undergoing cardiac surgery, and 1% of cardiac surgery patients will require mechanical circulatory support using Veno-Arterial ExtraCorporeal Membrane…
- Trial name
- AKI-ECMO (NCT04082312)
- Testing
- No intervention
- Where
- France
- Volunteers
- 347 people
- Sponsor
- Groupe Hospitalier Pitie-Salpetriere
Heart Failure, Diastolic, Heart Failure, Preserved Ejection Fraction
Relative Importance of Cardiovascular Risk Factors and Echocardiographic Parameters Affecting Left Atrial Strain
The goal of this observational study is to learn about left atrial reservoir strain in patients with heart failure with preserved ejection fraction.
- Trial name
- RICH-LAST (NCT05638230)
- Testing
- Left atrial reservoir strain
- Where
- South Korea
- Volunteers
- 2,500 people
- Sponsor
- Yonsei University
Heart Failure, Cognitive Impairment
Reducing Cognitive Impairment by Management of Heart Failure as a Modifiable Risk Factor
This study will test the feasibility and effectiveness of an innovative model of care for cognitively impaired patients with heart failure.
- Conditions
- Heart Failure, Cognitive Impairment, Dementia, Left Ventricular Dysfunction
- Trial name
- Cog-HF (NCT06088212)
- Testing
- Disease management program
- Where
- Australia
- Volunteers
- 168 people
- Sponsor
- Baker Heart and Diabetes Institute
Pre-Eclampsia, Cardiovascular Diseases
Pre-eclampsia and Future Cardiovascular Health: An Underused Opportunity to Improve Family Health
Background: PE (pre-eclampsia) is a common pregnancy-specific vascular hypertensive disease affecting 3-5% of pregnancies. PE independently increases the risk for premature cardiovascular disease (CVD) in mothers and their…
- Conditions
- Pre-Eclampsia, Cardiovascular Diseases, Cardiovascular Risk Factor, Gestational Hypertension
- Trial name
- FINNCARE (NCT04676295)
- Testing
- Face-to-face and web-based lifestyle intervention
- Where
- Finland
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Cardiovascular Diseases, Elderly Patients
Prediction Model of Cardiac Risk for Dental Extraction in Elderly Patients With Cardiovascular Diseases
This study intends to investigate the relevant risk factors of perioperation complications or mortality in older patients with cardiac diseases undergoing teeth extraction surgery and this study aims to quantify the risk factors…
- Conditions
- Cardiovascular Diseases, Elderly Patients, Tooth Extraction
- Trial name
- NCT03211312
- Where
- China
- Volunteers
- 833 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Cardiovascular Diseases, Metabolic Syndrome
Diets, Lipoproteins and Inflammation Markers
Systematic inflammation and lipid profiles are two major therapeutic targets for cardiovascular diseases. The effectiveness of vegan diet has been reported (doi: 10.3389/fnut.2022.807810).
- Conditions
- Cardiovascular Diseases, Metabolic Syndrome, Diet, Healthy, Vegan Diet
- Trial name
- NCT05423457
- Testing
- Vegan diet
- Where
- Taiwan
- Volunteers
- 21 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Lung Diseases, Sleep Apnea Syndromes
Sleep Heart Health Study (SHHS) Data Coordinating Center
To test whether sleep-disordered breathing is associated with an increased risk of coronary heart disease, stroke, all-cause mortality, and hypertension.
- Conditions
- Lung Diseases, Sleep Apnea Syndromes, Cardiovascular Diseases, Heart Diseases
- Trial name
- SHHS (NCT00005275)
- Volunteers
- 6,441 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Idiopathic Ventricular Fibrillation, Cardiac Arrest, Out-Of-Hospital
MEdical Treatment in Idiopathic Ventricular Fibrillation Patients
A person who has experienced a cardiac arrest with no apparent cause is at risk of having recurrent cardiac arrest. Hence an implantable cardioverter-defibrillator (ICD) is recommended on empirical grounds.
- Trial name
- RIME-IVF (NCT07405229)
- Testing
- Beta-blocker treatment group
- Where
- 2 sites in Denmark
- Volunteers
- 218 people
- Sponsor
- Bo Gregers Winkel
Sarcopenia, Cardiovascular Risk Factor
Reversing Muscle Loss With Exercise Training and Daily Consumption of Pomegranate Juice
A research study regarding the body's response to several weeks of training using short sprints and pomegranate juice supplementation
- Trial name
- NCT03258346
- Testing
- Inertial Load Cycling Training, Pomegranate Juice
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
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