Clinical trials: Cardiovascular Disease Risk Factors
Hypertension, Dyslipidemia
Nutrition and Exercise Intervention Study
The purpose of the present study was to clarify the effects of increase in physical activity on incidence and surrogate marker of cardiovascular diseases.
- Conditions
- Hypertension, Dyslipidemia, Diabetes, Low Back Pain
- Trial name
- NEXIS (NCT00926744)
- Testing
- physical activity
- Where
- Japan
- Volunteers
- 1,085 people, healthy volunteers welcome
- Sponsor
- National Institute of Health and Nutrition
Cardiovascular Disease, Inflammation
Effect of a Spice Blend on Cardiovascular Risk Factors and Diet Satisfaction
This study is a randomized 3-period crossover, controlled feeding study designed to evaluate the effects of the most commonly consumed spices in the U.S.
- Trial name
- NCT03064932
- Testing
- Controlled feeding diet
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Penn State University
Coronary Artery Disease, Acute Coronary Syndrome
A Registry Study on Genetics and Biomarkers of Acute Coronary Syndrome
This is a national registry study to determine genetics risk factors and serial biomarkers of Acute Coronary Syndrome.
- Conditions
- Coronary Artery Disease, Acute Coronary Syndrome, Acute Myocardial Infarction, Unstable Angina
- Trial name
- ARSGB-ACS (NCT03752515)
- Where
- 6 sites in China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Beijing Institute of Heart, Lung and Blood Vessel Diseases
Hypertension, Cardiovascular Diseases
Management of Hypertension and Multiple Risk Factors to Enhance Cardiovascular Health
High blood pressure (BP) is a serious public health problem responsible for heart attack, stroke and kidney failure. One in four adults in Singapore has hypertension.
- Trial name
- NCT02330224
- Testing
- Hypertension Management Intervention
- Where
- 2 sites in Singapore
- Volunteers
- 100 people
- Sponsor
- Duke-NUS Graduate Medical School
Cardiovascular Diseases, Type 2 Diabetes Mellitus (T2DM)
EValuation Of poLygenic Scores and CT imAging In Risk Factor Modification in Patients With diabEtes
This study is a three-arm, parallel-group, randomised controlled trial evaluating the effect of using cardiac CT imaging or polygenic risk score in cardiovascular risk factor modification in patients with diabetes.
- Trial name
- VOLTAIRE (NCT07091162)
- Testing
- CTCA results, PRS results
- Where
- Australia
- Volunteers
- 79 people
- Sponsor
- Monash University
Cardiovascular Diseases
Effects of Dark Chocolate on the Risk Factors of Cardiovascular Diseases
Cardiovascular disease (CVD) is the number one cause of death in the US. Epidemiologic evidence supports that antioxidant-rich diets promote health and attenuate or delay the onset of CVD.
- Trial name
- NCT06808282
- Testing
- White chocolate, Dark chocolate
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Diabetic Foot
Image Features of LSCI and Thermography for Determining the Risk Factor (0,1,2 and 3) of Developing Diabetic Foot Ulcer
Diabetic foot ulcers are one of the complications of diabetes mellitus. These wounds are often the result of diabetes-related neuropathy and/or an ischemic foot. Even with great care, recurrent ulcers are common.
- Trial name
- NCT05845242
- Volunteers
- 80 people
- Sponsor
- Ziekenhuisgroep Twente
Childhood Brain Tumor, Childhood Hodgkin Lymphoma
Dietary and Exercise Interventions in Preventing Cardiovascular Disease in Younger Survivors of Leukemia, Lymphoma, or Brain Tumors
This clinical trial studies dietary and exercise interventions in preventing cardiovascular disease in younger survivors of childhood cancer.
- Conditions
- Childhood Brain Tumor, Childhood Hodgkin Lymphoma, Childhood Non-Hodgkin Lymphoma, Malignant Childhood Neoplasm
- Trial name
- NCT02000986
- Testing
- Specimen Collection/Risk Factor Assessment -> Diet/Exercise -> Chemotherapy
- Sponsor
- Virginia Commonwealth University
Stroke, Ischemic, Cardiovascular Risk Factor
Development of a Prognostic Tool for the Stratification of Cardiovascular Risk in Patients With Ischemic Stroke
The availability of several high-cost strategies for the prevention of cardiovascular morbidity and mortality in patients with established cardiovascular disease highlights the necessity of reliable risk stratification of these…
- Conditions
- Stroke, Ischemic, Cardiovascular Risk Factor, Cardiovascular Diseases, Cardiovascular Morbidity
- Trial name
- NCT04189497
- Where
- Greece
- Volunteers
- 3,500 people
- Sponsor
- University of Thessaly
Atherosclerosis, Metabolic Syndrome
Risk Factor Analysis for Coronary Atherosclerosis Measured by MDCT
Coronary MDCT (multi-detector computed tomography) has been useful screening imaging modality for the coronary artery disease. Recently, novel adipokines and hepatokines as well as various inflammatory markers have been known as…
- Trial name
- NCT01589224
- Where
- South Korea
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Korea University
Diabetes, Hypertension
Simultaneous Risk Factor Control Using Telehealth to slOw Progression of Diabetic Kidney Disease (STOP-DKD)
Diabetic kidney disease (DKD) is associated with high rates of cardiovascular events and death. In addition, DKD is the major cause of end-stage renal disease (ESRD) in the United States.
- Conditions
- Diabetes, Hypertension, Diabetic Kidney Disease
- Trial name
- STOP-DKD (NCT01829256)
- Testing
- Pharmacist telehealth intervention
- Where
- United States
- Volunteers
- 285 people
- Sponsor
- Duke University
Insulin Resistance, Cardiovascular Disease
Processing Responses of Grains (PRO-Grains) Study
The primary objective of this pilot study will be to examine the effects of consuming whole grains, differing in the degree of processing, on insulin sensitivity and other cardiometabolic risk factors.
- Conditions
- Insulin Resistance, Cardiovascular Disease, Diabetes
- Trial name
- NCT02186353
- Testing
- Partial feeding study
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Major Adverse Cardiac Events, Adverse Effect of Unspecified General Anesthetic
Adverse Events in Acute Limb Ischemic Patient Undergoing Revascularization
Acute limb ischemia is one of the devastating vascular emergencies that lead to life and limb loss if the appropriate treatment is not reached.The revascularization is a cornerstone in treating acute limb ischemia.
- Trial name
- NCT05362266
- Where
- 2 sites in Thailand
- Volunteers
- 240 people
- Sponsor
- Mahidol University
Covid19, Cardiovascular Risk Factor
Cardiovascular Risk Stratification in Covid-19
This retrospective double-cohort study seeks to: 1. Describe the cardiovascular manifestations and electrophysiological (EP) substrate in COVID-19 infection and their association with clinical outcomes; and 2.
- Trial name
- CaVaR-Co19 (NCT04555187)
- Where
- United States
- Volunteers
- 1,355 people
- Sponsor
- Oregon Health and Science University
Cardiovascular Diseases
Brazilian Cardioprotective Nutritional Program Trial
There are no studies exploring the benefits of a diet composed of typical Brazilian food in the secondary prevention of cardiovascular diseases.
- Trial name
- BALANCE (NCT01620398)
- Testing
- BALANCE, Control diet
- Where
- 35 sites in Brazil
- Volunteers
- 2,534 people
- Sponsor
- Hospital do Coracao
Metabolic Syndrome, Physical Activity
Medical and Physiological Benefits of Reduced Sitting
The most important objective of this randomized controlled trial in subjects with increased cardiovascular and metabolic risk factors is to investigate whether only reduced daily sitting improves human cardiovascular and…
- Conditions
- Metabolic Syndrome, Physical Activity, Insulin Resistance, Cardiovascular Diseases
- Trial name
- NCT03101228
- Testing
- Reduced sitting
- Where
- Finland
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Metabolic Syndrome, Obesity
Identification of Early Cardiovascular Disease Risk Factors in Normal-weight Obesity
The purpose of this study is to identify early cardiovascular disease risk factors in those with "normal-weight obesity" (i.e., normal body, but high body fat percentage) that better track with their long-term cardiovascular…
- Trial name
- NCT05008952
- Testing
- High-fat shake
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University
Microalbuminuria, Endothelial Dysfunction
Microalbuminuria as a Cardiovascular Risk Factor (PRECISED Substudy)
Microalbuminuria (MA) is an independent cardiovascular risk factor in diabetic and non-diabetic subjects. However, in the setting of type 2 diabetes, microalbuminuria could be a marker of either early diabetic nephropathy or…
- Conditions
- Microalbuminuria, Endothelial Dysfunction, Diabetic Nephropathy, Diabetic Retinopathy
- Trial name
- NCT02409511
- Testing
- non intervention
- Where
- Spain
- Volunteers
- 75 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Atherosclerosis, Cardiovascular Diseases
Dietary Fat, Plasma Lipids, and Other CHD Risk Factors
To assess the extent to which consumption of different sources of hydrogenated fat relative to unhydrogenated oil or butter alters plasma lipoprotein concentrations and measures of lipid metabolism.
- Conditions
- Atherosclerosis, Cardiovascular Diseases, Coronary Disease, Heart Diseases
- Trial name
- NCT00005532
- Sponsor
- Tufts University
Covid19, Thrombosis Embolism
COVID-19 Registry to Assess Frequency, Risk Factors, Management, and Outcomes of Arterial and Venous Thromboembolic Complications
Novel coronavirus 2019 (COVID-19) has emerged as a major international public health concern. While much of the morbidity and mortality associated with COVID-19 has been attributed to acute respiratory distress syndrome (ARDS) or…
- Conditions
- Covid19, Thrombosis Embolism, DVT, Pulmonary Embolism
- Trial name
- CORONA-VTE NET (NCT04535128)
- Testing
- No intervention
- Where
- United States
- Volunteers
- 11,000 people
- Sponsor
- Brigham and Women's Hospital
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