Clinical trials: Cardiovascular Disorders
Patients With Cardiovascular Disease, Healthy Participants
OCTA in Cardiovascular Disease and Healthy Controls
This prospective clinical study will involve the non-invasive assessment of retinal vessels using OCTA (Cirrus OCT 6000 AngioPlex) and scanning laser Doppler flowmetry (SLDF) in patients with cardiovascular disease and healthy…
- Trial name
- NCT07359664
- Testing
- Retinal vascular assessment using OCTA and SLDF
- Where
- Germany
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Hypertension
Effects of Nebivolol on Skeletal Muscle During Exercise in Hypertensive Patients
The purpose of this study is to determine if Nebivolol improves microvascular perfusion in skeletal muscle during exercise in hypertensive patients and whether this improvement is accompanied by reduction in vascular oxidative…
- Trial name
- NCT01501929
- Testing
- Metoprolol succinate, Nebivolol, Non-invasive measurement of Cardiac Output (CO)
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Infectious Endocarditis
Evaluation of an Antibiotic Regimen Pharmacokinetic Applicable to Enterococcus Faecalis Infective Endocarditis
The clinical trial is designed as a phase II, crossover clinical trial. It will be carried out in healthy volunteers, who will receive two different antibiotic regimen based on ceftriaxone.
- Trial name
- NCT03681431
- Testing
- Ceftriaxone 4g/ 24h, Ceftriaxone 2g/ 12h
- Where
- Spain
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Cardiovascular Disease
The CHYMASE Angiotensin-(1-12) Axis in Cardiovascular Disease
Study is to evaluate the Chymase Angiotensin-(1-12) in cardiovascular disease
- Trial name
- NCT03826745
- Testing
- Plasma/Urine
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Trinity Hypertension & Metabolic Research Institute
Atrial Fibrillation, Acute Coronary Syndrome
Antithrombotic Triple Therapy in Humans
Background:The acute coronary syndrome (ACS) is a complication of coronary artery disease (CAD) and associated with increased mortality.
- Trial name
- NCT01812200
- Testing
- Dabigatran, Ticagrelor, ASA, Rivaroxaban, Ticagrelor, ASA, Phenprocoumon, Ticagrelor, ASA
- Where
- Austria
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Cerebrovascular Disorder, Healthy
Magnetic Resonance Imaging Studies of Motor and Thought Processes
Magnetic resonance imaging (MRI) is a diagnostic tool that creates high quality images of the human body without the use of X-ray (radiation).
- Conditions
- Cerebrovascular Disorder, Healthy, Movement Disorder, Nervous System Disease
- Trial name
- NCT00001361
- Where
- United States
- Volunteers
- 610 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Prehypertension
Effect and Safety of Marealis RPC (Refined Peptide Concentrate) in Mild or Moderate Hypertensive Subjects
Hypertension is an important risk factor of cardiovascular (CVD) and renal diseases. Epidemiological studies show that there is a direct relationship between blood pressure and CVD, and cardiovascular mortality increases…
- Trial name
- NCT01974570
- Testing
- Marealis refined peptide concentrate
- Where
- 13 sites in United States, Canada and 2 more
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- KGK Science Inc.
Stroke, Caregiver Burden
Family-centered Support Program for Caregivers of Stroke Survivors
The goal of this study is to evaluate the effect of a family-centered support program on the care burden, depressive symptoms, perceived social support, and quality of life of stroke survivor' caregivers and on care recipients'…
- Trial name
- NCT05668169
- Testing
- Family-centered support program for caregivers of stroke survivors
- Where
- Taiwan
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- wen yu Kuo, assistant professor
Heart Failure
A Study Designed to Assess the Mass Balance Recovery, Absorption, Metabolism, Excretion of [14C]AZD5462 and the Absolute Bioavailability of AZD5462
A study to investigate how the body breaks down and gets rid of the test medicine, AZD5462. To help investigate this, the test medicine is radiolabelled, which means that the test medicine has a radioactive component (carbon-14)…
- Trial name
- NCT06989983
- Testing
- AZD5462 film-coated tablet, [14C]AZD5462 Solution for Infusion, [14C]AZD5462 Oral Solution
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Acute Effect of Local Vibration Application in Stroke Patients
Acute Effect of Local Vibration in Stroke Patients
The aim of the research is to examine the acute effect of local vibration application on gait and balance in stroke patients.
- Trial name
- NCT06610994
- Testing
- local vibration apply
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Acute Ischemic Stroke
Arterial Spin Label Depicted Ischemic Stroke Cohort (ASLIS)
Establish a clinical cohort of acute ischemic stroke patients and find the determinant of the prognosis.
- Trial name
- ASLIS (NCT05920902)
- Testing
- routine therapy of acute ischemia stroke
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ruijin Hospital
Death, Carotid Artery Disease
NOR-SYS: The Norwegian Stroke in the Young Study
NOR-SYS is a clinical research program about young ischemic stroke patients from 15 to 60 years. Patients, partners and the couple´s adult children who are at least 18 years old, are all invited to ultrasound examinations due to…
- Conditions
- Death, Carotid Artery Disease, Cardiovascular Disease, Peripheral Artery Disease
- Trial name
- NOR-SYS (NCT01597453)
- Testing
- Lifestyle counseling
- Where
- Norway
- Volunteers
- 1,062 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Metabolic Syndrome, Diabetes
Biomarkers of Metabolic Syndrome and Prediabetes
The purpose of this study is to investigate the feasibility of using salivary biomarkers to screen for complications of metabolic syndrome including prediabetes.
- Conditions
- Metabolic Syndrome, Diabetes, Prediabetes, Hypertension
- Trial name
- NCT01086137
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- West Virginia School of Osteopathic Medicine
Coronary Artery Disease (CAD), Cardiac Rehab
The Effect of Cardiac Rehabilitation on Ferroptosis in Patients With Coronary Artery Disease
Coronary artery disease (CAD) remains a major global health concern and is the leading cause of cardiovascular mortality worldwide.
- Conditions
- Coronary Artery Disease (CAD), Cardiac Rehab, Ferroptosis
- Trial name
- NCT07722637
- Testing
- Cardiac Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Myopia, Mental Health
Intervention for Preventing Myopia and Multimorbidity in Children
This study aims to develop and evaluate a scalable, hybrid intervention model for the co-prevention of myopia, obesity, and mental health issues among children.
- Conditions
- Myopia, Mental Health, Cardiovascular Health Status
- Trial name
- NCT07294222
- Testing
- Standard School Health Education, Multi-component Health Promotion Package
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Fangbiao Tao
Hypertension
Development of Green Mei Products for the Prevention of Metabolic Syndrome
The aim of this study is to investigate the antihypertensive effects of Mei-Gin formula-4 (MGF-4) and Mei-Gin formula-7.
- Trial name
- NCT05039437
- Testing
- MGF-4, MGF-7
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Parkinson Disease, Stroke
Smart Wearable Device (gaitQ): Walk Better Project
This study will be underpinned by the new MRC guidelines for developing a complex intervention with a participatory design methodology that uses evidence-based research and behaviour change models alongside COSMIN methodology for…
- Conditions
- Parkinson Disease, Stroke, Multiple Sclerosis, Osteoporosis
- Trial name
- NCT05913219
- Where
- United Kingdom
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Atherosclerosis, Diabetes
Strategies for Inflammation and Cardiovascular Disease (CVD) Prevention
The long-term goal of the proposed research is to identify and develop effective interventions to decrease persistent, low-level inflammation and risk of CVD.
- Trial name
- SICVDP (NCT02165228)
- Testing
- Mindfulness-based stress reduction, Nutrition Enhancement
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Montana State University
Pulmonary Hypertension
Evaluation of Echocardiographic Indices and Blood Biomarkers in Group 1 Pulmonary Hypertension
To evaluate different echocardiographic indices in diagnosis and follow up of group 1 pulmonary hypertension. To evaluate blood biomarkers (troponin, uric acid and micro RNA) in naïve group 1 pulmonary hypertension.
- Trial name
- NCT04279145
- Testing
- swan ganze catheter /echocardiography
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Assiut University
Abruptio Placentae; Affecting Fetus or Newborn
Normotensive and Hypertensive Placental Abruptions
Placental abruption is a significant cause of both maternal morbidity and neonatal morbidity and mortality. Most abruptions accept to be related to a chronic placental disease process.
- Trial name
- NCT04449601
- Testing
- clinical assesment
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Hatice Akkaya
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