Clinical trials: Cardiovascular Disorders
Intraoperative Hypotension
The Use of Integrated Pulmonary Index During Cesarean Section Under Spinal Anesthesia
Postspinal hypotension (PSH) is a common side effect with an incidence of 15.3 to 33% that can result in organ hypoperfusion and ischemic events.
- Trial name
- NCT05237856
- Testing
- Capnometry Monitorization
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Intra-abdominal Fat, Metabolic Syndrome
Habitual Diet and Avocado Trial
The Habitual Diet and Avocado Trial will evaluate the effects of providing one avocado per day for recommended consumption over a 6 month period in a cohort of approximately 1000 free-living participants with increased waist…
- Conditions
- Intra-abdominal Fat, Metabolic Syndrome, High Cholesterol, Triglycerides High
- Trial name
- HAT (NCT03528031)
- Testing
- Intervention Daily Avocado
- Where
- 4 sites in United States
- Volunteers
- 1,008 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Stress Disorders, Post-Traumatic
Role of Sympathetic Overactivity and Angiotensin II in PTSD and CV
The purpose of this study is to find out why patients with post-traumatic stress disorder (PTSD) have an increased risk for heart disease and high blood pressure later in life.
- Trial name
- ANG-P (NCT02560805)
- Testing
- Microneurography, Combat virtual reality video clip, Handgrip Exercise
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Emory University
Hypertension, Sleep Disorder
Study of Disrupted Sleep in Somali Americans
The aims of this study are to determine the types and severity of previously undiagnosed sleep deficiencies in otherwise healthy Somali Americans, apply a research framework to define psychosocial, behavioral, environmental, and…
- Conditions
- Hypertension, Sleep Disorder, Healthy
- Trial name
- NCT05411029
- Testing
- 24 hour blood pressure (BP) monitoring, Polysomnography
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Atherosclerosis, Congestive Heart Failure
Dallas Heart Study 2: Return Clinic Visit for the Dallas Heart Study Cohort
The Dallas Heart Study (DHS-1) is a large, multi-ethnic, population-based epidemiological study designed to identify determinants of atherosclerotic heart disease (ASHD) in a representative United States (US) urban environment.
- Conditions
- Atherosclerosis, Congestive Heart Failure, Left Ventricular Hypertrophy, Diabetes Mellitus
- Trial name
- NCT00344903
- Where
- United States
- Volunteers
- 3,400 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Diabetic Foot, Diabetes Mellitus, Type 2
Foot-Ankle Exercise and Walking Exercise on Diabetes Mellitus Patients
The primary purpose of this study is to determine the effectiveness of foot-ankle exercise and walking exercise on foot neuropathy, stress, and quality of life (QoL) among people with diabetes mellitus (PWDM).
- Conditions
- Diabetic Foot, Diabetes Mellitus, Type 2, Diabetic Neuropathies, Diabetes Type 2
- Trial name
- NCT06518486
- Testing
- Foot-ankle exercise, Walking exercise, Usual care and health education
- Where
- 5 sites in Indonesia
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Healthy Adults
Use of Stable Carbon And Nitrogen Isotopes to Improve Dietary Assessment for Cardiovascular Disease
In this research study, the investigators will use a novel approach to measure what people eat. The goal is to find out whether stable isotopes that can be measured in blood, hair, and fingernails are better at measuring what…
- Trial name
- I-CAN (NCT04933656)
- Testing
- one 24 hr cycle of meals at a 2000 kcal level, one 24 hr cycle of meals at a 2000 kcal level + one serving sugar sweetened beverage, one 24 hr cycle of meals at a 2000 kcal level + two servings sugar sweetened beverage
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Diego
Aldosteronism
Postoperative Cardiovascular Index Change of Primary Aldosteronism
Primary aldosteronism (PA), characterized by an inappropriate production of aldosterone, is far more common than is usually perceived.
- Trial name
- TAIPAI (NCT00746070)
- Testing
- with the clinical treatment ( ex adrenalectomy or spironolactone
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Stroke
Perception of Electrical Stimuli in Individuals With Stroke
To successfully manipulate objects in one's surroundings, such as when lifting a cup, one must accurately perceive their physical interactions.
- Trial name
- NCT05465005
- Testing
- Torque Generation
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Netta Gurari
Hypertension
Hypertension and Retinal Microvascular Dysfunction
Hypertension is a worldwide health care burden that affects the structure and function of the macro- and microcirculation. Non-invasive vascular biomarkers are essential to timely diagnose end organ damage to improve…
- Trial name
- HyperVasc (NCT04763005)
- Testing
- HIIT exercise intervention, Physical activity recommendations
- Where
- Switzerland
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Basel
Angina Pectoris
Absorption and Pharmacokinetics of Nitroglycerin to a New Formulation
The study evaluate the absorption rate of different sublingual formulation of nitroglycerine (NTG) either in the form of available tablets or a new rapid absorbable gelation capsule formulation "NTG1523" by determining T-max and…
- Trial name
- NCT03777605
- Testing
- Nitroglycerin 0.4 MG
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Kolding Sygehus
Atherosclerotic Cardiovascular Disease, Cardiovascular Disease
Intima-Medial Thickness Guidance of Primary Prevention in Relatives of Patients With Early onSet Atherosclerosis
The primary objective of this study is, to instigate a reduction in atherosclerotic burden within the carotid arteries in the intervention group compared to the control group and to demonstrate parallel improvements in…
- Trial name
- IMPRESS (NCT01330602)
- Testing
- IMPRESS intervention
- Where
- 3 sites in Singapore
- Volunteers
- 1,310 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Stroke
Proximal Priority Versus Distal Priority Robotic Priming Effects in Patients With Chronic Stroke
This is a single-blind randomized comparative efficacy study involving 54-72 participants with chronic stroke. Participants will be randomized into proximal priority robotic group or distal priority robotic group and receive 18…
- Trial name
- NCT04446273
- Testing
- Bi-Manu-Track
- Where
- 4 sites in Taiwan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Obesity, Hyperlipidemia
Effects of Dietary Antioxidants on Cardiovascular Risk Factors
The aim of the Antioxidant Study was to compare the efficacy of foods naturally rich in antioxidants with that of antioxidants in a pill form on markers of inflammation and plasma cholesterol in healthy adults at risk of…
- Conditions
- Obesity, Hyperlipidemia, Hypertension
- Trial name
- NCT00756405
- Testing
- Antioxidant diet, Antioxidant supplement
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Christopher Gardner
Obesity, Childhood, Risk Factor, Cardiovascular
The Svendborg-project
The main aim of this study is to describe differences in development of health and motor performance over time in relation to type of school and other background variables.
- Conditions
- Obesity, Childhood, Risk Factor, Cardiovascular, Sports Injury, Physical Activity
- Trial name
- CHAMPS-DK (NCT03510494)
- Testing
- Augmented physical education program
- Where
- Denmark
- Volunteers
- 1,209 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Varicose Vein
Effect of Intensive Sports Practice on Lower Limb Varicose Veins
Compare the frequency of varicose veins in the lower limbs in a population exposed to intensive sport compared to individuals matched by sex, age and body mass index (BMI) did not have an intensive sport.
- Trial name
- VARISPORT (NCT02846051)
- Testing
- venous mapping
- Where
- France
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Franche-Comté
Hypercholesterolemia
Cholesterol Lowering Effect of Cardio-Complement, an Ayurveda Formulation
The aim of this feasibility study was to assess the lipid-lowering effects and safety of a Ayurveda formulation containing Terminalia Arjuna, Withania Sominifera, Garcinia Cambogia and piperine (as bioenhancer)
- Trial name
- NCT04974853
- Testing
- Cardio-complement
- Where
- India
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- NMP Medical Research Institute
Healthy
From FAST to FAST BEE - Video-Based Stroke Mnemonic Pilot
This online study evaluates immediate learning outcomes after viewing a short animated FAST BEE stroke-education video (1 minute 51 seconds).
- Trial name
- FAST BEE (NCT07440602)
- Testing
- FAST BEE Stroke Education Video (1 minute 51 seconds)
- Where
- India
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- Jubilee Mission Medical College and Research Institute
Sudden Cardiac Death, Prolonged QTc Interval
Smoking and Ventricular Repolarization
Randomized controlled trial of acute use of electronic cigarette or tobacco cigarette on parameters of ventricular repolarization.
- Trial name
- NCT03916341
- Testing
- EC with nicotine, EC without nicotine, control
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Diabetes Mellitus
Role of Red Blood Cells in Cardiovascular Disease
The risk of myocardial infarction is dependent on cardiovascular risk factors including type 2 diabetes (T2D) but underlying mechanisms are poorly understood.
- Trial name
- NCT07151222
- Where
- Sweden
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
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