Clinical trials: Cardiovascular Outcome
Diabetes (DM), Cardio Vascular Disease
Nut Consumption and Prevention of Non-communicable Diseases: A Global Individual Participant Data Meta-analysis
The relationship between nut consumption and the risk of developing non-communicable diseases (NCDs) has been a subject of growing interest.
- Conditions
- Diabetes (DM), Cardio Vascular Disease, Cancer, Dementia
- Trial name
- NUTPOOL (NCT07205978)
- Where
- 2 sites in Denmark, Spain
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Institut Investigacio Sanitaria Pere Virgili
Brain Infarction, Ischemic Stroke
Searching for Explanations for Cryptogenic Stroke in the Young: Revealing the Etiology, Triggers, and Outcome
BACKGROUND: In industrialized countries a considerable and increasing proportion of strokes occur at younger ages. Stroke at young age causes marked disability at worst and thus long-standing socioeconomic consequences and…
- Conditions
- Brain Infarction, Ischemic Stroke, Thrombosis, Foramen Ovale, Patent
- Trial name
- SECRETO (NCT01934725)
- Where
- 19 sites in Estonia, Finland and 11 more
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- SECRETO Study Consortium
ST Elevation Myocardial Infarction, HF - Heart Failure
Diagnostic Values of Galectin-3, Soluble ST2 and BNP in Predicting the Clinical Outcome of ST-Segment Elevation Myocardial Infarction Patients
An acute ST-elevation myocardial infarction occurs due to occlusion of one or more coronary arteries, causing transmural myocardial ischemia which in turn results in myocardial injury or necrosis.
- Conditions
- ST Elevation Myocardial Infarction, HF - Heart Failure, Stable Angina
- Trial name
- NCT05246215
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Blood Pressure, Pulse Wave Analysis
Association of Synchronous Four-limb blOod pRessure and Pulse Wave velocIty With Cardiovascular Events
A multicenter prospective registry planned to recruit more than 100 000 patients 50 years old and older was carried out in China.
- Conditions
- Blood Pressure, Pulse Wave Analysis, Ankle Brachial Index, Patient Outcome Assessment
- Trial name
- ASORPWICE (NCT03521739)
- Where
- 19 sites in China
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Hemorrhagic Stroke, Acute
Predictive Value of Human Microbiome and Serological Markers for Clinical Outcome of Cerebral Hemorrhage
Objective: To explore the predictive value of characteristic disorder of intestinal flora for clinical prognosis in patients with intracerebral hemorrhage.
- Conditions
- Hemorrhagic Stroke, Acute, Outcomes, Metabolites
- Trial name
- NCT05551923
- Testing
- intestinal flora disturbance
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Coma
Multimodal Resonance Imaging for Outcome Prediction on Coma Patients
Stroke, traumatic head injury, subarachnoid hemorrhage and cerebral anoxia are main causes of a coma condition implying severe brain damage and thus, poor prognosis.
- Trial name
- MRI-Coma (NCT00577954)
- Testing
- Multimodal MRI
- Where
- France
- Volunteers
- 417 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Coronary Occlusion
Optical Coherence Tomography to Improve Outcome for Coronary Revascularisation Using Bioresorbable Vascular Scaffolds
Fully Bioresorbable Vascular Scaffolds (BVS) have been introduced with the objective to preserve native vessel geometry, allow for adaptive vessel remodeling with late lumen gain, restore physiological vasomotion, and avoid late…
- Trial name
- OPTICO-BVS (NCT02683356)
- Testing
- OCT-guided PCI, Angiography-guided PCI
- Where
- Switzerland
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Anesthesia, Hypotension
Prospective Trial of Alerting to Extended Hypotensive Exposures on Long-Term Outcome After Surgery
Patients undergoing anesthesia for non-cardiac surgery will be randomized to either having their anesthesia team alerted or kept blinded to extended periods of less than normal blood pressure with the goal of studying if…
- Trial name
- SLUScore™ (NCT02217969)
- Testing
- Electronic alert to SLUScore increase
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- St. Louis University
Ischemic Stroke, Transient Ischemic Attack
Efficacy of Ticagrelor Plus Aspirin in Mild Non-cardioembolic Ischemic Stroke
This is a randomized, controlled, active comparator arm, outcome assessor blind, parallel group design on 90 patient with diagnosis of ischemic stroke admitted in Bou-Ali Sina Hospital, Sari,Iran.The aim of study is assess the…
- Trial name
- TACAMINIS (NCT04738097)
- Testing
- Ticagrelor 90mg, Clopidogrel 75 mg
- Where
- 2 sites in Iran
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Mazandaran University of Medical Sciences
Caregivers, Burnout, Psychological
Efficacy of a Multicomponent and Interdisciplinary Intervention on the Care Ability and Burden of Family Caregivers of People With Chronic Cardiocerebrovascular Diseases
The purpose of this intervention is to improve the caregiving ability of family caregivers of people with cardiovascular diseases and therefore reduce burden caregiver through face-to-face, virtual interdisciplinary educational…
- Trial name
- Emiicare (NCT04645290)
- Testing
- Intervention group: Educational Intervention "KARER"
- Where
- 3 sites in Colombia
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Claudia Aristizábal
Hemianopsia, Homonymous
Testing of a Functional Outcome Measure for Those With Visual Field Defects
This study is designed in two Phases. In phase 1, the Functional Outcome Measure will be tested to determine its validity and reliability in three populations, subjects that have not had a stroke and have no visual field defect…
- Trial name
- FOM (NCT00731796)
- Testing
- Functional Outcome Measure
- Where
- 3 sites in United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- NovaVision, Inc.
Myocardial Protection in TOF Repair
Myocardial Protection and Clinical Outcome in Patients Undergoing Tetralogy of Fallot Repair : A Randomized Study of Two Different Cardioplegia Technique
Myocardial protection and clinical outcome in patients Undergoing tetralogy of fallot repair: a randomized study of Two cardioplegic techniques.
- Trial name
- TOF (NCT02646254)
- Testing
- blood cardioplegia, del nido cardioplegia
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- SUNDER LAL NEGI
Ischemic Stroke
Selenium and Ischemic Stroke Outcome
Selenium is a trace element essential to human health.Selenium protection against cellular damage by oxygen radicals is accomplished through selenoproteins.
- Trial name
- NCT02505295
- Testing
- Selenium, normal saline
- Where
- Iran
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Mazandaran University of Medical Sciences
Chronic Subdural Hematoma
Postoperative Balloninflation After Evacuation of cSDH
In this prospective, randomized, multicenter trial shall patients with chronic subdural hematoma (cSDH) recruited, who were surgically treated.
- Trial name
- BANISH (NCT04060186)
- Testing
- Balloninflation
- Where
- Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Johann Wolfgang Goethe University Hospital
Sepsis, Septic Cardiomyopathy
Identification of Cardiovascular and Molecular Prognostic Factors for the Mid- and Long-term Outcome of Sepsis
Sepsis is a life-threatening condition which can affect people of any age. An infection triggers a host response resulting in organ failure.
- Conditions
- Sepsis, Septic Cardiomyopathy, Cardiomyopathies
- Trial name
- ICROS (NCT03620409)
- Where
- Germany
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- Jena University Hospital
Healthy Elderly Individuals With High LDL-cholesterol or Risk of Cardiovascular Disease
Low- and Moderate-intensity Statin and Clinical Outcome of Primary Prevention in Individuals Aged >70 Years: the SCOPE-70 RCT Study
One of the most effective drug in the primary prevention of cardiovascular disease is statins. The protective effects of statin on developement of cardiovascular disease has been demonstrated in elderly individuals.
- Trial name
- NCT03770312
- Testing
- Low intensity statin, Moderate intensity statin
- Where
- South Korea
- Volunteers
- 724 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Cardiovascular Diseases
Impact of Rapeseed and Sunflower Oils on Proteomic Biomarkers of Diseases.
This study will test the impact of vegetable oils with contrasting fatty acids composition on biomarkers of health (cardiovascular, kidney diseases and diabetes) after twelve weeks supplementation.
- Trial name
- DOC (NCT04867629)
- Testing
- Rapeseed oil, Sunflower oil
- Where
- United Kingdom
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Aneurysmal Subarachnoid Hemorrhage
Human Albumin for Clinical Outcome in Aneurysmal Subarachnoid Hemorrhages
Aneurysmal subarachnoid hemorrhage (aSAH) is a dreadful acute neurological condition with overwhelmingly high rate of associated morbidities and mortality.
- Trial name
- HASH (NCT06548477)
- Testing
- Human albumin
- Where
- Qatar
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
Ischemic Stroke, Cancer
Mechanism and Outcome of Acute Ischemic Stroke in Cancer Patients
Stroke is a part of circulatory diseases which are the primary cause of death in Egypt. It accounts 14% of all deaths thus ranks the 2nd after ischemic heart disease. Cancer accounts 9% of population mortality in Egypt.
- Trial name
- NCT04195048
- Testing
- Risk factors
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Mansoura University Hospital
Abortion, Spontaneous, Pregnancy Complications
Relation Between Subclinical Hypothyroidism and Outcome of Pregnancy
Studies have demonstrated a relationship between subclinical hypothyroidism and obstetrics complications like preterm delivery, pre-eclampsia, placental abruption and stillbirth.
- Conditions
- Abortion, Spontaneous, Pregnancy Complications, Subclinical Hypothyroidism
- Trial name
- GravThyr (NCT01335802)
- Where
- Denmark
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Naestved Hospital