Clinical trials: Cardiovascular Outcomes
Peripheral Arterial Disease, Claudication
Outcomes in Femoropopliteal Disease Stratified by Translesional Pressure Gradient
1. To perform an observational analysis to determine if mean translesional gradient measurements (TLG) are associated with differences in clinical outcomes in patients with femoropopliteal arterial disease and claudication. 2.
- Trial name
- NCT02387658
- Testing
- translesional gradient measurement
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- North Texas Veterans Healthcare System
Acute Ischemic Stroke
Association of Prophylactic Use of Stress Ulcer Drugs and Clinical Outcomes in Patients With Acute Anterior Circulation Thrombectomy
Ischemic stroke accounts for a relatively high proportion of strokes. In recent years, intravenous thrombolysis and endovascular therapy have significantly improved the revascularization rate in patients with large vessel…
- Trial name
- NCT05845372
- Where
- 19 sites in China
- Volunteers
- 2,592 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Coronary Artery Disease, Obesity
Cardiovascular Outcomes Of Diet Counseling
(1) What effect does behavioral counseling for vegan, for low to moderate fat, and for lowered carbohydrate diets have on coronary blood flow? (2) What are the effects of different diet protocols when caloric intake and exercise…
- Trial name
- NCT00324545
- Testing
- Medium-intensity Minimally-directive Counseling
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Camelot Foundation
Percutaneous Coronary Intervention, Platelet Aggregation Inhibitors
Algorithm-based Tailoring of Dual Antiplatelet Therapy to Improve Outcomes Following Percutaneous Coronary Interventions
The use of aspirin combined with a P2Y12 inhibitor (dual antiplatelet therapy, DAPT) represents the standard of care for patients undergoing percutaneous coronary intervention (PCI) with stent implantation.
- Conditions
- Percutaneous Coronary Intervention, Platelet Aggregation Inhibitors, Coronary Artery Disease
- Trial name
- TAILOR-DAPT (NCT05732701)
- Testing
- Algorithm-guided DAPT duration, Standard-of-care DAPT duration
- Where
- 4 sites in Bosnia and Herzegovina, Italy and 1 more
- Volunteers
- 2,788 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Coronary Artery Disease, Cancer
Time From PCI to Cancer Surgery and Cardiovascular and Oncologic Outcomes
To evaluate the association between time from PCI to cancer surgery and cardiovascular and oncologic outcomes in early-stage cancer patients, A retrospective, population-based cohort study was conducted using data from the Korean…
- Trial name
- NCT06357000
- Volunteers
- 3,621 people
- Sponsor
- Samsung Medical Center
Heart Failure, Congestive Heart Failure
Personalized Voice Activated Wellness Assistants for Patients With Heart Failure
The Alexa+ Study will compare the use of the Amazon Echo Dot with Alexa voice technology in patients with chronic heart failure to those receiving standard of care heart failure management on changes in health and…
- Trial name
- NCT03707275
- Testing
- Alexa+, Standard of Care Arm
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Medstar Health Research Institute
Type 2 Diabetes Mellitus, Hypertension
Evaluation of Improved Outcomes Among Ambulatory Diabetes and/or Hypertensive Patients - an Intervention Study (CPCLINT)
The goal of this interventional study is to compare improved outcomes among diabetes and/or hypertensive patients sequel to educational intervention.
- Trial name
- CPCLINT (NCT05996601)
- Testing
- Educational intervention
- Where
- Nigeria
- Volunteers
- 400 people
- Sponsor
- University of Ibadan
Heart Failure, Coronary Artery Disease
The Helios Heart Registry: A Standardized Registry for Patients With Specific Cardiac Diseases
Investigator-initiated, prospective, non-randomized, open label, non-interventional multicenter registry to evaluate current treatment of three major cardiovascular disease entities in clinical practice using a standardized…
- Conditions
- Heart Failure, Coronary Artery Disease, Atrial Fibrillation
- Trial name
- H²-Registry (NCT04844944)
- Where
- 10 sites in Germany
- Volunteers
- 24,000 people
- Sponsor
- Helios Health Institute GmbH
Cerebrovascular Accident, Transient Ischemic Attack
Safety Study of Atomoxetine and Cerebrovascular Outcomes
Using a proprietary insurance health claims database, Eli Lilly and Company has contracted with an external party to conduct a retrospective cohort study of health claims for the time period from 1 January 2003 through 31…
- Conditions
- Cerebrovascular Accident, Transient Ischemic Attack, ADHD
- Trial name
- NCT00634439
- Testing
- atomoxetine, Stimulants, No intervention (general population)
- Where
- United States
- Volunteers
- 72,000 people
- Sponsor
- Eli Lilly and Company
Cardiac Arrest, Sepsis
Improving Outcomes After Time Sensitive Prehospital Interventions: Rescu Epistry
Rescu Epistry includes data points pertaining to prehospital and in-hospital clinical treatments and responses to therapy, survival to discharge and functional outcome data for all cases.
- Conditions
- Cardiac Arrest, Sepsis, Trauma, Stroke
- Trial name
- NCT04110912
- Testing
- This is a registry and no interventions are taking place.
- Where
- 3 sites in Canada
- Sponsor
- Unity Health Toronto
Diabetic Retinopathy
10-year Progression of Diabetic Retinopathy: Identification of Signs and Surrogate Outcomes
To characterize both functionally and morphologically initial Diabetic Retinopathy (DR) stages and their progression over a period of 10 years.
- Trial name
- PROGRESS10 (NCT04650165)
- Where
- Portugal
- Volunteers
- 119 people
- Sponsor
- Association for Innovation and Biomedical Research on Light and Image
Peripheral Vascular Disease
Pilot Study to Determine Percent Tissue Perfusion and Cellular Viability Using SPY Imaging
Little is known about chronic wound microenvironments, especially in peripheral vascular disease (PVD) and diabetic patients. At the demarcation line, the percentage of viable cells and tissue is unclear.
- Trial name
- NCT01522495
- Testing
- SPY Imaging, ICG dye (0.2 - 0.5 mg/kg), SPY Imaging
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Georgetown University
COVID-19, Cardiopulmonary Disease
Comparing Inpatient COVID-19 Outcomes in 2 Different PT Dosing Groups
The objective of this study is to compare the effects of twice-a-day 15-minute sessions of inpatient physical therapy (PT) to the standard daily 30 minute sessions.
- Conditions
- COVID-19, Cardiopulmonary Disease, Weakness, Muscle, Hypoxia
- Trial name
- CCPT (NCT04844307)
- Testing
- Shorter duration higher frequency PT, Standard PT
- Sponsor
- Montefiore Medical Center
Acute Cerebral Stroke Within 12 Hours for the First Time
Dl-3-n-butylphthalide and Cerebrolysin Treatment in Acute Ischemic Stroke
The investigators conducted a randomized, double-blind, trial enrolled 60 patients within 12 hours of acute ischemic stroke (AIS) in China.
- Trial name
- NCT02149875
- Testing
- Dl-3-n-butylphthalide, Cerebrolysin
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Shanghai 6th People's Hospital
Stroke, Acute Coronary Syndrome
Factors Associated With Perioperative Outcomes in Non-emergency Surgery
This epidemiological study investigates the association of recent stroke, acute coronary syndrome or pneumonia and adverse perioperative outcomes following elective non-cardiac and cardiac surgery using routinely collected UK…
- Conditions
- Stroke, Acute Coronary Syndrome, Pneumonia
- Trial name
- NCT02455492
- Testing
- stroke or myocardial infarction or pneumonia
- Volunteers
- 266,436 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
COPD (Chronic Obstructive Pulmonary Disease), Cardiovascular Diseases
Cardiovascular Assessment and Treatment During COPD Exacerbation to Improve Diagnosis and Outcomes
This is a research study involving patients hospitalized for COPD flare-ups. Patients will be assigned using a non-randomized, sequential allocation strategy (a control cohort followed by an intervention cohort) to two groups…
- Trial name
- CATCH (NCT06723795)
- Testing
- Cardiologist evaluation, Pulmonologist evaluation
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Stroke, Sensorimotor Impairment Affecting the Upper Limb
Reliability of Sensor-Derived Measurements of the SENSorized Fugl-Meyer (FMA) in Subjects with Stroke Outcomes
This study will be conducted at a single research center, the main objective of the study will be to evaluate the efficacy, safety, and accuracy of a medical device that has not yet been commercialized; therefore, it is still…
- Conditions
- Stroke, Sensorimotor Impairment Affecting the Upper Limb, 18 Years and Over
- Trial name
- FMA-SENS (NCT06893367)
- Testing
- IMU and RealSense Cameras
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Diagnosis of Coarctation of the Aorta and VSD, Surgical Repair at CHOA
Surgical Outcomes in Pediatric Patients With Coarctation and VSD
Recently, a paper was published that compared outcomes of patients requiring repair of aortic coarctation and ventricular septal defect.
- Conditions
- Diagnosis of Coarctation of the Aorta and VSD, Surgical Repair at CHOA, Between January 1, 2002 and December 31, 2005
- Trial name
- NCT00327795
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Children's Healthcare of Atlanta
Acute Kidney Injury, Kidney Failure Chronic
French AKI Registry (FAKIR): A Multicenter Study on the In-Hospital Management and Outcomes of Severe Acute Kidney Injury in Nephrology Units
Acute Kidney Injury (AKI) is a common and serious condition in hospitalized patients, especially when it reaches stages 2 or 3 according to the KDIGO classification.
- Conditions
- Acute Kidney Injury, Kidney Failure Chronic, Cardiorenal Syndrome, Renal Replacement Therapies
- Trial name
- FAKIR (NCT07123324)
- Volunteers
- 750 people
- Sponsor
- University Hospital, Strasbourg, France
Pulmonary Embolism and Thrombosis, Deterioration, Clinical
An Observational Study About Adverse Outcomes in Acute Pulmonary Embolism Patients
This multi-center retrospective study collected clinical, laboratory, and CT pulmonary angiography parameters with acute pulmonary embolism patients from admission to predict adverse outcomes within 30 days after admission into…
- Trial name
- NCT05481242
- Testing
- retrospective observational study
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Shengjing Hospital
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