Clinical trials: Cardiovascular Outcomes
Coronary Artery Bypass Graft Surgery Patients
Improving Outcomes and Quality of Life After CABG
The principal objective to this randomized trial is to compare the efficacy of two strategies of intra-operative hemodynamic management during cardiopulmonary bypass among patients undergoing primary elective coronary artery…
- Trial name
- NCT00256620
- Testing
- Mean arterial pressure during cardiopulmonary bypass 80 mmHg vs. customized
- Where
- United States
- Volunteers
- 412 people
- Sponsor
- Weill Medical College of Cornell University
Stroke
Clinical Charactaristics , Risk Factors and Outcomes of Stroke in Pediatric Patients at Assiut University Children's Hospital
Summary of the study is to recognize clinical picture , to identify risk factors and evaluate outcomes of stroke in pediatric patients
- Trial name
- NCT07120568
- Volunteers
- 45 people
- Sponsor
- Assiut University
Hypertension
Effects of a Brown Seaweed Tart Cherry Blend in Mild-moderate Hypertension
The brown seaweed species Ascophyllum nodosum is rich in bioactive polysaccharides, proteins, peptides, lipids, pigments, and polyphenols.
- Trial name
- NCT06559982
- Testing
- Brown seaweed and tart cherry blend
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Central Lancashire
Relapsed/Refractory Multiple Myeloma (RRMM)
A Study of Clinical Outcomes in Patients With Relapsed/Refractory Multiple Myeloma (RRMM) Treated With T-cell Redirectors Outside of Clinical Trials
The purpose of this study is to describe the use of teclistamab/talquetamab in the treatment of patients with RRMM outside of clinical trials.
- Trial name
- REALiTEC/TAL (NCT06285318)
- Testing
- Teclistamab, Talquetamab
- Where
- 68 sites in Denmark, France and 9 more
- Volunteers
- 900 people
- Sponsor
- Janssen-Cilag Ltd.
PTA (Percutaneous Transluminal Angioplasty ), Femoropopliteal Artery Disease
Clinical Outcomes of GENOSS PCB for Femoropopliteal Artery Disease
The GENOSS PCB study aims to evaluate the safety and efficacy of a Paclitaxel-coated PTA Balloon Catheter(GENOSS® PCB) in patients with the femoropopliteal artery disease.
- Trial name
- GENOSS PCB (NCT07399080)
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Genoss Co., Ltd.
Psoriasis, Psoriatic Arthritis
Prevention of Cardiovascular Disease and Mortality in Patients With Psoriasis or Psoriatic Arthritis
The goal of this research is to test a novel centralized care coordinator program to assist patients with psoriatic disease in lowering their risk of cardiovascular disease through the application of standard of care approaches…
- Conditions
- Psoriasis, Psoriatic Arthritis, Psoriatic Conditions, Cardiovascular Diseases
- Trial name
- CP3 (NCT05908240)
- Testing
- Care Coordinator Model
- Where
- 20 sites in United States
- Volunteers
- 603 people
- Sponsor
- University of Pennsylvania
Cardiogenic Shock, IABC Procedure
Intra-aortic Balloon Counterpulsation (IABC) Compliance
The investigators intend to study how baseline arterial compliance (as defined by stroke volume/pulse pressure) influences the clinical success of intraaortic balloon counterpulsation (IABC) in patients with cardiogenic shock…
- Conditions
- Cardiogenic Shock, IABC Procedure, Intraaortic Balloon Counterpulsation (IABC)
- Trial name
- NCT07402018
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Thomas Jefferson University
Resting Heart Rate, Blood Glucose Control
Assessing the Effects of Cool Roofs on Indoor Environments and Health in Tavua, Fiji
Ambient air temperatures in Fiji are increasing due to climate change. Solutions are needed to build heat resilience in communities and adapt.
- Conditions
- Resting Heart Rate, Blood Glucose Control, Depression, Heat-related Symptoms
- Trial name
- NCT07592117
- Testing
- Cool roof
- Where
- Fiji
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Hypertension, Resistant to Conventional Therapy, Atrial Fibrillation
Combined Treatment of Resistant Hypertension and Atrial Fibrillation
The purpose of this study is the comparative evaluation of systolic blood pressure (SBP) lowering, atrial fibrillation (AF) recurrence and clinical data in patients with paroxysmal/persistent AF and resistant hypertension…
- Trial name
- NCT01117025
- Testing
- Circumferential PV isolation, Circumferential PVI+renal denervation
- Where
- 2 sites in United States, Russia
- Volunteers
- 26 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Myocardial Infarction
Study of the Immediate and Long-term Outcomes of the Disease in Patients With Left Ventricular Aneurysm Complicated and Uncomplicated by Thrombosis After Transmural Myocardial Infarction, According to the Hospital Registry: SIBYL
A prospective non-interventional study aimed to evaluate the immediate and long-term outcomes in patients with left ventricular aneurysm after transmural myocardial infarction.
- Trial name
- SIBYL (NCT04901091)
- Testing
- Not Provided
- Where
- Russia
- Volunteers
- 49 people
- Sponsor
- National Medical Research Center for Therapy and Preventive Medicine
Stroke
Long Term Effects of Action Observation Therapy and Mirror Therapy on Upper Limb Functions
There will be a long term effects of action observation therapy and mirror therapy on upper limb functional outcomes after subacute stroke.
- Trial name
- NCT06027125
- Testing
- Action observation Therapy, Mirror Therapy
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Ischaemic Stroke
XILO-FIST, the Effect of Allopurinol on the Brain Heart and Blood Pressure After Stroke
Recurrent stroke and cognitive decline are common after ischaemic stroke. Allopurinol, a drug usually used to treat gout, has been shown to reduce heart ischaemia, heart size, and arterial stiffness and to relax brain blood…
- Trial name
- XILO-FIST (NCT02122718)
- Testing
- Allopurinol
- Where
- 21 sites in United Kingdom
- Volunteers
- 464 people
- Sponsor
- NHS Greater Glasgow and Clyde
Colitis, Ischemic
Study of Ischemic Colitis Compared to Other Diagnoses in Patients With Lower Gastrointestinal Bleeding
The purpose of this study is to study the demographic,laboratory,endoscopic, and outcomes of ischemic colitis patient presented with severe lower gastrointestinal bleeding compared to other diagnoses.
- Trial name
- NCT01078324
- Where
- United States
- Volunteers
- 550 people
- Sponsor
- University of California, Los Angeles
Stroke
Repetitive Peripheral Magnetic Stimulation Enhances Modified Constraint-Induced Movement Therapy Outcomes After Stroke
This is a retrospective observational study to investigate the effect of repetitive peripheral magnetic stimulation (rPMS) combined with modified constraint-induced movement therapy (m-CIMT) on upper extremity and finger fine…
- Trial name
- NCT07559747
- Testing
- rPMS, m-CIMT
- Where
- China
- Volunteers
- 50 people
- Sponsor
- The First Hospital of Jilin University
Acute Ischemic Stroke
PROMISE: PRedictors Of Good outcoMes in Thrombectomy for Large Infarct Core Stroke Evaluation
Identify the factors associated with a favorable clinical outcome in participants with acute ischemic stroke and large core infarcts within 24 hours of onset who are treated with endovascular intervention.
- Trial name
- NCT06016348
- Testing
- Endovascular treatment
- Where
- 4 sites in Vietnam
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- 115 People's Hospital
Dehydration, Ischemic Stroke
BUN/Cr-based Hydration Therapy to Improve Outcome of Patients With Acute Ischemic Stroke
English Synopsis I. Title of Study: A trial of BUN/Cr-based hydration therapy to reduce stroke-in-evolution and improve short-term functional outcomes for dehydrated patients with acute ischemic stroke-version 2. II.
- Trial name
- NCT05121389
- Testing
- normal saline
- Where
- Taiwan
- Volunteers
- 288 people
- Sponsor
- Chang Gung Memorial Hospital
Type 2 Diabetes
A Two-armed Real-world Study of Ozempic (OW Semaglutide) to Evaluate Its Adherence and Persistence Compared With Other Anti-diabetic Drugs Among Adult T2DM Patients in China
The study is testing the incidence of MACE and incidence of renal events between Ozempic® users and users with other anti-diabetic medications in T2D patients.
- Trial name
- SPOTLIGHT (NCT07456774)
- Where
- China
- Volunteers
- 100,000 people
- Sponsor
- Novo Nordisk A/S
Liver Cancer, Surgery
Study of Liver Resection With Versus Without Hepatic Inflow Occlusion for the HBV-related HCC
The study aims to compare the perioperative and long-term outcomes of liver resection for HBV-related HCC with versus without hepatic inflow occlusion.
- Trial name
- OHx-NOHx (NCT02563158)
- Testing
- non-occlusion technique
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Chinese PLA General Hospital
Abdominal Aortic Aneurysms
Talent Aortic Cuff Stent Graft System Compassionate Use Registry
An evaluation of the TALENT Aortic Cuff in patients with existing AneuRx stent grafts who have experienced sub-optimal stent graft outcomes and are not deemed suitable candidates for treatment with an AneuRx Aortic Cuff.
- Trial name
- NCT00604643
- Testing
- TALENT Aortic Cuff Abdominal Stent Graft
- Where
- 50 sites in United States
- Sponsor
- Medtronic Cardiovascular
Coronary Embolism, Atrial Fibrillation (AF)
AF Coronary Embolism Long Term Outcomes
Introduction Coronary embolism (CE) is a relatively rare but significant cause of non-atherosclerotic acute myocardial infarction (AMI), representing about 3% of all AMI cases, though it is likely underdiagnosed.
- Trial name
- NCT06948240
- Testing
- AF related coronary embolism
- Where
- Spain
- Volunteers
- 400 people
- Sponsor
- Fundacion Miguel Servet
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