Clinical trials: Cardiovascular Risk Factor
Ischemic Stroke
Stenting vs. Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis
PRIMARY HYPOTHESIS: Compared with intensive medical therapy alone, intracranial angioplasty and stenting combined with intensive medical therapy will decrease the risk of the primary endpoint by 35% over a mean follow-up of two…
- Trial name
- SAMMPRIS (NCT00576693)
- Testing
- intracranial angioplasty and stenting, intensive medical management
- Where
- 50 sites in United States
- Volunteers
- 451 people
- Sponsor
- Medical University of South Carolina
HIV Infections, Dyslipidemias
Lipid Profile and Diabetes Mellitus in People With HIV
Traditional risk factors for cardiovascular diseases have been shown to have an even higher impact in the HIV infected population.
- Conditions
- HIV Infections, Dyslipidemias, Diabetes Mellitus, Cardiovascular Risk Factor
- Trial name
- NCT04125784
- Where
- Austria
- Volunteers
- 450 people
- Sponsor
- Moritz Oberndorfer
Cardiovascular (CV) Risk
Cardiovascular Prevention Supported by Digital Technology: Comparison With the Traditional Model
Cardiovascular diseases represent one of the leading causes of morbidity and mortality worldwide. Prevention in patients at cardiovascular risk is essential to reduce the incidence of cardiovascular events and slow the…
- Trial name
- DIGITAL PREV (NCT07608926)
- Testing
- Recommendations to the patient.
- Where
- Italy
- Volunteers
- 144 people
- Sponsor
- Maria Cecilia Hospital
Type 2 Diabetes Mellitus
Feasibility Of Individualized Dietary Plan (Idp) On Glycemic Control And Total Cholestrol In Diabetic Patients At Diabetes Hospital And Research Centre Peshawar
This study aims to test whether a personalized meal plan (Individualized Dietary Plan, IDP) is practical and helpful for adults with type 2 diabetes in Peshawar, Pakistan.
- Trial name
- NCT07030543
- Testing
- Individualized Dietary Plan (IDP) for Type 2 Diabetes, Usual care
- Where
- Pakistan
- Volunteers
- 122 people
- Sponsor
- Khyber Medical University Peshawar
Histiocytosis, Langerhans-Cell
Cardiovascular Risk Factors and LCH in Adults
Langerhans-cell histiocytosis (LCH) is a rare disease with features of chronic inflammation and hypopituitarism, conditions associated with increased risk of cardiovascular diseases.
- Trial name
- NCT00483925
- Where
- Greece
- Volunteers
- healthy volunteers welcome
- Sponsor
- Laikο General Hospital, Athens
Cardiovascular Factor Risk
Statin Choice Decision Aid Implementation First Phase
This study is designed to answer a key question in the field of implementation science. Specifically, it seeks to determine if a proposed model for the implementation and scale-up of healthcare innovations (the AIDED model) is…
- Trial name
- SCIP1 (NCT02375815)
- Testing
- Statin Choice Implementation
- Where
- 4 sites in United States
- Volunteers
- 313 people
- Sponsor
- Mayo Clinic
Middle Cerebral Artery Aneurysm
Risk Factors of Middle Cerebral Artery Aneurysm.
According to the current view, cerebral aneurysms are acquired degenerative lesions resulting from hemodynamic stress. This single-center case-control study will be carried out at the Department of Neurosurgery, Regional Hospital…
- Trial name
- MCAA (NCT03493035)
- Testing
- Computed tomography angiography (3D CTA), Transcranial color-coded sonography (TCCS)
- Where
- Poland
- Volunteers
- 190 people
- Sponsor
- Medical University of Silesia
Coronary Artery Disease
Development of a Risk Prediction Algorithm Through the Investigation of Genetic Risk Factors and the Complexity of Coronary Artery Disease to Estimate Future Risk of Cardiovascular Events: Angiographic (SYNTAX Score), Clinical and Pharmacogenetic Analysis.
The purpose of the research project is to investigate the potential association of 207 genetic polymorphisms with the complexity and the severity of coronary artery disease (SYNTAX score), along with the patients' response to…
- Trial name
- GESS (NCT03150680)
- Testing
- SNPs associated with CAD, SNPs associated with pharmacological response to clopidogrel and statins
- Where
- Greece
- Volunteers
- 1,080 people
- Sponsor
- AHEPA University Hospital
Fish Consumers
Effect of Fish Consumption on Cardiovascular Risk Factors
IConsumption of fish provides a vital contribution to the survival and health of a significant portion of the world's population.
- Trial name
- NCT03111784
- Testing
- Fish consumption and lipid profiles
- Where
- Sri Lanka
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eastern University, Sri Lanka
Risk Factor, Cardiovascular
Home-based HIIT in a Primary-care Setting for at Risk Individuals: A Multidisciplinary Approach
The prevalence of chronic inactivity related diseases including obesity, insulin resistance and type 2 diabetes mellitus has reached global epidemic proportions.
- Trial name
- NCT04553614
- Testing
- Home-based HIIT, Control
- Where
- United Kingdom
- Volunteers
- 154 people
- Sponsor
- Liverpool John Moores University
Cardiovascular Risk Factor
Reducing Cardiovascular Risk of African Americans
Diseases such as hypertension and stroke affect mid-life and older African Americans at higher rates than Whites, negatively affecting health status of this group.
- Trial name
- NCT03339050
- Testing
- Health for Hearts United
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- Florida State University
Coronary Artery Disease
Comparison of Predictive Factors Related to Coronary Artery Disease
In Taiwan, heart disease and cerebrovascular disease ranked the second and third of ten leading causes of death in female in 2007; half of these deaths is due to coronary artery disease (CAD).
- Trial name
- NCT01136343
- Testing
- lifestyle modified project
- Where
- Taiwan
- Volunteers
- 130 people
- Sponsor
- Taipei Medical University WanFang Hospital
Cardiovascular Risk Factor
Comparison of Extra-Virgin and Refined Olive Oil on Some Cardiovascular Risk Factors
Consumption of extra-virgin olive oil has beneficial effects on cardiovascular risk factors. The purpose of this study is to compare the effects of extra-virgin olive oil and refined olive oil, in adjunct to conventional medical…
- Trial name
- NCT03796780
- Testing
- Extra-Virgin Olive Oil, Refined Olive Oil
- Where
- Iran
- Volunteers
- 40 people
- Sponsor
- Javad Nasrollahzadeh
Weight Loss, Diet, Healthy
Delicious Eating for Life in Southern Homes
This study will compare a new weight loss program that focuses on a healthy eating pattern, with WW™ (formally Weight Watchers), an effective and widely available weight loss program.
- Conditions
- Weight Loss, Diet, Healthy, Cardiovascular Risk Factor
- Trial name
- DELISH (NCT04302727)
- Testing
- Med-South Weight Loss Intervention, WW
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Essential Hypertension
Effects of Angiotensin II Receptor Blocker Compared With Diuretics in High-risk Hypertensive Patients
The aim of the study is to investigate the optimized treatment strategy of hypertension, so as to make more patients to reach the blood pressure goals and to reduce cardio-cerebrovascular events.
- Trial name
- CHIEF (NCT01011660)
- Testing
- Amlodipine, Telmisartan, Amiloride Compound , Simvastatin
- Where
- China
- Volunteers
- 13,542 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Cardiovascular Risk Factor
Correlation Between the SPhENo-Cardiograph™, a Seismocardiograph Device, and GE Vivid Q, an Echocardiograph, for Known Systemic Timing Intervals (STI)
The study Sponsor, Heart Force Medical Inc. (HFM), has developed a patented medical device called the SPhENo-CardiographTM. The SPhENo-Cardiograph™ provides a non-invasive assessment of the electro-mechanical function of the…
- Trial name
- NCT02636023
- Testing
- SPhENo-Cardiograph
- Where
- Canada
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Heart Force Medical Inc.
Cardiovascular Diseases, Atherosclerosis
YOUhealTH - a Study to Improve Cardiovascular Health in Adolescents and Adults
The goal of this single-center prospective randomized controlled parallel 2-arm intervention study is to test a lifestyle intervention focusing on diet and physical activity in students and at least one legal guardian to improve…
- Trial name
- NCT05741827
- Testing
- Lifestyle intervention
- Where
- Austria
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- VASCage GmbH
Exercise Anaphylaxis
The Impact of High Intensity Exercise Upon EPC Number and Function in Young Women
The purpose of the study is to examine the effects of different exercise intensity training programs upon blood vessel function and circulating blood cells involved in blood vessel repair in young women.
- Trial name
- NCT01314573
- Testing
- Sprint interval exercise, Maximal continuous exercise
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Coronary Heart Disease, Dyslipidemia
Cardiovascular Risk Factor Management in HIV Infection
There is growing evidence that antiretroviral therapy (ART) increases the risk of coronary heart disease (CHD) through metabolic side effects, such as dyslipidemia, insulin resistance, and type II diabetes.
- Conditions
- Coronary Heart Disease, Dyslipidemia, Diabetes Mellitus, Non-Insulin-Dependent, HIV Infection
- Trial name
- NCT00264394
- Testing
- Updated CHD risk profiles, Guidelines
- Where
- 7 sites in Switzerland
- Volunteers
- 4,097 people
- Sponsor
- University Hospital, Basel, Switzerland
Healthy People
The Effects of Freeze-Dried Whole Grape Powder on Chronic Disease and Cardiovascular Risk Factors-a Pilot Study
Cardiovascular disease (CVD) is responsible for 1 out of every 5 deaths, is the number one killer of Americans, killing about 700K US adults per year (1).
- Trial name
- NCT06006182
- Testing
- Grape Powder
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- California State Polytechnic University, Pomona