Clinical trials: Cardiovascular Risks
Cardiovascular Risk Factor, Metabolic Disease
Effects of Shockwave Therapy Versus Radiofrequency
The main objective of this study is to compare the effect of 6 sessions of shock wave therapy versus radiofrequency followed by a protocol of moderate aerobic exercise, in the reduction of adiposity and abdominal flaccidity, in…
- Conditions
- Cardiovascular Risk Factor, Metabolic Disease, Photoaging
- Trial name
- NCT04282057
- Testing
- Radiofrequency, Aerobic exercise, Shock wave therapy
- Where
- Portugal
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Escola Superior de Tecnologia da Saúde do Porto
Arrhythmias, Cardiac, Tachycardia, Ventricular
Cardiac Arrhythmias at Extreme Altitude
Background: Exposure to high altitudes has been associated with an increased risk of cardiac arrhythmias in healthy subjects and an increased risk of sudden cardiac death.
- Conditions
- Arrhythmias, Cardiac, Tachycardia, Ventricular, Tachycardia, Supraventricular, Bradycardia
- Trial name
- SUMMIT (NCT05676398)
- Testing
- Ambulatory rhythm recording
- Where
- Nepal
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Cardiovascular Risk Factor, Lipemia
Postprandial Monocyte Maturation and Vascular Dysfunction Following High-Fat Meals - Study 1
The purpose of this research study is to examine the effect of high-fat meals on the health of blood vessels. In addition, the study will examine how exercise/fitness/physical activity impacts blood vessels after consumption of a…
- Trial name
- NCT03958734
- Testing
- High-fat meal
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Clonal Hematopoiesis, Clonal Hematopoiesis of Indeterminate Potential
CHIP in Health and Disease
Clonal hematopoiesis (CH), including clonal hematopoiesis of indeterminate potential (CHIP), is an age-associated condition characterized by the expansion of hematopoietic stem and progenitor cell clones carrying acquired somatic…
- Conditions
- Clonal Hematopoiesis, Clonal Hematopoiesis of Indeterminate Potential, Clonal Cytopenia of Undetermined Significance (CCUS), Myelodysplastic Syndrome
- Trial name
- CHIP2 (NCT07780552)
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- VASCage GmbH
Aspirin Resistance, Pharmacological Aspirin Non-responsiveness
Mechanism Based Resistance to Aspirin
The purpose of this research is to study why some people do not respond to the benefits of aspirin therapy. The benefit of aspirin is cardioprotection, or decreasing the risk of heart attack and/or stroke.
- Trial name
- NCT00948987
- Testing
- Aspirin
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Cardiovascular Diseases
Visualization of Asymptomatic Atherosclerotic Disease for Optimum Cardiovascular Prevention
The purpose of VIPVIZA is to assess the impact of pictorial information about asymptomatic atherosclerotic disease to both physician and patient, for improving physicians' adherence to prevention guidelines and patient perception…
- Trial name
- VIPVIZA (NCT01849575)
- Testing
- Intervention
- Where
- Sweden
- Volunteers
- 3,532 people, healthy volunteers welcome
- Sponsor
- Umeå University
Schizophrenia, Schizoaffective Disorder
Cardio Risk of Acute Schizophrenia Olanzapine Duke
Primary Objective: To compare added metformin and/or added simvastatin versus no intervention in reducing or eliminating increased cardiovascular risk (as estimated by elevation in non-HDL cholesterol levels) during the treatment…
- Trial name
- CRASOD (NCT00672464)
- Testing
- Olanzapine, Metformin, Simvastatin
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Duke University
Shift Work Type Circadian Rhythm Sleep Disorder, Chronobiology Disorders
Effects of Shift Work on Nurse Staff Health
Shift work deeply impacts on temporal organization leading to a circadian desynchronization, which translates into a worsening of the sleep quality and work ability during waking hours.
- Conditions
- Shift Work Type Circadian Rhythm Sleep Disorder, Chronobiology Disorders, Mood Swing, Physical Activity
- Trial name
- Turnisti (NCT03453398)
- Testing
- Shifts working hours with different schedules
- Where
- Italy
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Blood Pressure Monitoring, Ambulatory, Cardiovascular (CV) Risk
Work-Related Frustration and Higher Cardiovascular Risk Blood Pressure Profiles
Background: Mental health is a national priority in France, especially in the workplace. The impact of poor quality of life at work on mental health has been demonstrated.
- Conditions
- Blood Pressure Monitoring, Ambulatory, Cardiovascular (CV) Risk, Quality of Life at Work, Hypertension
- Trial name
- TRACA (NCT07740434)
- Where
- 3 sites in France
- Volunteers
- 316 people, healthy volunteers welcome
- Sponsor
- University of Burgundy
Obesity, Cardiovascular Risk Factor
The Pitt Retiree Study: A Diabetes Prevention Program for Medicare Eligible Older Adults
The Pitt Retiree Study (PRS) disseminates a novel, yet practical, diabetes prevention program among Medicare eligible adults in Western Pennsylvania.
- Conditions
- Obesity, Cardiovascular Risk Factor, Eating Behavior, Diet Modification
- Trial name
- PRS (NCT03192475)
- Testing
- GLB plus phone contacts, GLB plus newsletter contacts
- Volunteers
- 322 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Healthy Lifestyle, Overweight
Deaf Weight Wise: Community-engaged Implementation Research to Promote Healthy Lifestyle Change With Deaf ASL Users
The purpose of the Deaf Weight Wise Implementation Study is to study with diverse partners the approaches and strategies that lead to successful implementation of Deaf Weight Wise (DWW), an evidence-based healthy lifestyle…
- Conditions
- Healthy Lifestyle, Overweight, Obesity, Cardiovascular Risks
- Trial name
- NCT05211596
- Testing
- Deaf Weight Wise intervention
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Overweight and Obesity, Endothelial Dysfunction
Influence of Walnut Intake on Vascular Function and Metabolism
This study seeks to confirm and extend previous finding that four weeks of daily intake of 40 g of walnuts improve microvascular function, increasing the reactive hyperemia index (RHI), effects which were greatest in individuals…
- Conditions
- Overweight and Obesity, Endothelial Dysfunction, Cardiovascular Risk Factor
- Trial name
- NCT03900403
- Testing
- Walnut Intake
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Cardiovascular Diseases
Primary Care Audit of Global Risk Management
1. Assessing the perception of Canadian Primary Care Physicians towards global cardiovascular risk assessment. 2. Correlating physician perceptions to actual practice data, gathered via a retrospective chart audit. 3.
- Trial name
- PARADIGM (NCT00950703)
- Where
- Canada
- Volunteers
- 3,015 people, healthy volunteers welcome
- Sponsor
- Canadian Collaborative Research Network
Heart Disease Congenital
Support Tool for Families of High-Risk Children With Heart Disease During Hospital Admission and After Discharge
The goal of this study is to pilot the "support tool" in the Nemours Cardiac Center to assess acceptability and feasibility. This tool will be offered to 5 high-risk families, and they will be asked to complete a survey.
- Trial name
- NCT05926661
- Testing
- NCC Support Toolkit
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Atheroscleroses, Coronary
Dotatate to Locate Coronary Plaques at High-risk of Myocardial Infarction
To assess whether vulnerable coronary plaques have more uptake of 68Ga-Dotatate than non-vulnerable plaques.
- Trial name
- DOLPHIN (NCT05536960)
- Testing
- 68Ga-Dotatate PET/CT
- Where
- Netherlands
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Diabetes, Weight Gain
The GlasVEGAS Study (Glasgow Visceral & Ectopic Fat With Weight Gain in South AsianS)
South Asians have a much higher risk of diabetes compared to Europeans and investigators don't know why this is. Investigators think that South Asians' capacity to store fat safely under the skin is lower than Europeans, so they…
- Conditions
- Diabetes, Weight Gain, Weight Loss, Cardiovascular Disease
- Trial name
- GlasVEGAS (NCT02399423)
- Testing
- Weight gain, Weight loss
- Where
- United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Menopause Related Conditions, Vitamin D Deficiency
Vitamin D and Microvascular Function in Postmenopausal Women
Many observational studies have demonstrated links between serum levels of 25-hydroxyvitamin D [25(OH)D] and cardiovascular risk (CVR) factors. Microvascular dysfunction relates not only to CVR but also to metabolic disease.
- Conditions
- Menopause Related Conditions, Vitamin D Deficiency, Cardiovascular Diseases
- Trial name
- NCT05408273
- Testing
- Blood samples and Microvascular function assessment evaluated through laser-Doppler flowmetry by the LASER speckle contrast analysis (LASCA) device
- Where
- Brazil
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Schizophrenia Disorder, Metabolic Syndrome
Efficacy and Safety of Semaglutide Versus Placebo on Cardiometabolic Profile in Patients With Schizophrenia With Metabolic Syndrome
Patients with schizophrenia on second-generation antipsychotics have a high burden of metabolic syndrome and elevated cardiovascular risk, with few effective treatment options.
- Conditions
- Schizophrenia Disorder, Metabolic Syndrome, Antipsychotic-induced Weight Gain, Cardiovascular Risk
- Trial name
- NCT07770282
- Testing
- Semaglutide + TAU
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Contraception, Female Contraception
A Postmarketing Study of the Risk of Venous Thromboembolism (Blood Clots), Myocardial Infarction (Heart Attacks), and Stroke Among Women Using ORTHO EVRA (Norelgestromin and Ethinyl Estradiol Contraceptive Patch) Compared With Women Who Take Oral Contraceptives for Birth Control
The purpose of the study is to use data from a health care information database to assess the risk of venous thromboembolism (blood clots), myocardial infarction (heart attacks), and stroke among women using a transdermal…
- Trial name
- NCT00377988
- Testing
- Transdermal Contraceptive System, Norgestimate-containing oral contraceptives with EE
- Volunteers
- 423 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Cardiovascular Disease, Metabolic Syndrome X
Inflammatory Profiles of Children at High Risk for Atherosclerosis
The purpose of this study is to evaluate levels of inflammatory mediators in children at risk for cardiovascular disease due to family history.
- Conditions
- Cardiovascular Disease, Metabolic Syndrome X, Hypercholesterolemia, Inflammation
- Trial name
- NCT00115232
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.