Clinical trials: Cardiovascular Surgery
Intraoperative Hypotension
Advanced Cardiovascular Management in Major Non-cardiac Surgery.
This is a single center, randomised and controlled clinical triaI whose aim is to predict and treat in advance, intraoperative hypotension episodes.
- Trial name
- NCT07134530
- Testing
- HPI-driven intraoperative hemodynamic management strategy, GDT strategy
- Where
- Italy
- Volunteers
- 534 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Intracranial Aneurysm, Transradial Access(TRA)
Application of Brachial Plexus Block in Patients Undergoing Cerebral Aneurysm Embolization Via Transradial Approach
The aim of this study was toinvestigate the effect of BPB on outcome of upper extremity arteries in patients undergoing interventional embolization of intracranial aneurysms via TRA.
- Trial name
- ABPBCAETRA (NCT06035692)
- Testing
- Ropivacaine
- Where
- China
- Volunteers
- 176 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Thrombosis
STRATAGEM: Strategy for Managing Antiplatelet Therapy in the Perioperative Period of Non Coronary Surgery
The STRATAGEM trial is an investigator-driven French nationwide multicenter, randomized, double-blind, placebo-controlled trial comparing perioperative low-dose aspirin therapy versus placebo in the perioperative period in…
- Trial name
- STRATAGEM (NCT00190307)
- Testing
- aspirin 75 mg/day
- Where
- France
- Volunteers
- 293 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Vital Sign Monitoring, Post Operative Complications
Continuous Vital Sign Monitoring Versus Routine Spot-checks in Patients After Non-cardiac Surgery
The "COME ON, NOW!" trial is a randomized, single-center trial in patients recovering from non-cardiac surgery on normal wards investigating whether continuous vital sign monitoring - compared to routine spot-checks by nurses …
- Conditions
- Vital Sign Monitoring, Post Operative Complications, Non-cardiac Surgery, RCT
- Trial name
- COME ON NOW (NCT07385092)
- Testing
- Unblinded continuous vital sign monitoring, Blinded continuous vital sign monitoring
- Where
- Germany
- Volunteers
- 264 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Bradycardia
Brad Arrhythmia Induced by Repeated Succinylcholine During Gynecological Laparoscopic Surgery
Cardiac arrhythmias are a well-recognized complication of anesthesia for laparoscopy. The aim of this study was to evaluate the efficacy of atropine sulfate for prevention of brad arrhythmia induced by repeated succinylcholine…
- Trial name
- NCT02676011
- Testing
- IM atropine, IV atropine, Atropine mixed with second dose succinylcholine
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Assiut University
Arteriovenous Fistula, Arteriovenous Graft
A Randomised Trial Comparing Supraclavicular Block vs Supraclavicular and Pecs II Block in Arteriovenous Grafting
This study evaluates the addition of Pecs II block to ultrasound-guided supraclavicular brachial plexus block in patients undergoing arteriovenous graft creation surgery.
- Conditions
- Arteriovenous Fistula, Arteriovenous Graft, Kidney Failure, Chronic, Renal Failure, End-stage
- Trial name
- NCT02331030
- Testing
- Supraclavicular, Pecs II block, Ropivacaine 0.5% 20ml
- Where
- Singapore
- Volunteers
- 36 people
- Sponsor
- Changi General Hospital
End-stage Heart Failure
LVAD Versus GDMT in Ambulatory Advanced Heart Failure Patients
Heart failure is a severe disease affecting approximately 1-2% of the adult population in developed countries and around 26 million people worldwide.
- Trial name
- AMBU-VAD (NCT04768322)
- Testing
- HeartMate 3 TM Left Ventricular Assist System, Guideline Directed Medical Therapy
- Where
- 8 sites in France
- Volunteers
- 92 people
- Sponsor
- Hospices Civils de Lyon
Heart Failure, Excessive Amount of Blood / Fluid Transfusion
Anesthesia for Catheter Aortic Valve ImplantATIOn Registry
In modern cardiac surgery and cardiology Transcatheter Aortic Valve Implantation (TAVI) is an emerging procedure for high-risk patients that are assumed to be otherwise inoperable.
- Conditions
- Heart Failure, Excessive Amount of Blood / Fluid Transfusion, Intraoperative Cardiac Arrest During Cardiac Surgery, Critical Incident
- Trial name
- AVIATOR (NCT01390675)
- Where
- Germany
- Volunteers
- 10,000 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Piles
Prolapsed Hemorrhoids: Assessment of Various Surgical Modalities
Postoperative complications like pain, hemorrhage, anal stenosis, and incontinence, which can slow down recovery, are frequently associated with a standard hemorrhoidectomy.
- Trial name
- NCT07481812
- Testing
- LigaSure Hemorroidectomy, Stapled Hemorrhoidopexy, Traditional hemorroidectomy
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Theodor Bilharz Research Institute
Cardiovascular Surgical Procedures, Arthroplasty, Replacement
Trial to Reduce Antimicrobial Prophylaxis Errors (TRAPE)
The specific aims are to determine the incidence of medication errors related to antimicrobial prophylaxis for cardiovascular surgery, joint replacement surgery, and hysterectomies across a heterogeneous sample of hospitals…
- Conditions
- Cardiovascular Surgical Procedures, Arthroplasty, Replacement, Hysterectomy
- Trial name
- NCT00114036
- Testing
- Quality improvement strategies
- Where
- 3 sites in United States
- Sponsor
- Agency for Healthcare Research and Quality (AHRQ)
Venous Thromboembolism
Evaluation of AVE5026 as Compared to Enoxaparin for the Prevention of Thromboembolism in Patients Undergoing Total Hip Replacement Surgery
The primary objective was to compare the efficacy of once daily [q.d.] subcutaneous [s.c.] injections of Semuloparin sodium (AVE5026) with q.d. s.c.
- Trial name
- SAVE-HIP1 (NCT00697099)
- Testing
- Semuloparin sodium, Enoxaparin sodium
- Where
- 30 sites in United States, Argentina and 28 more
- Volunteers
- 2,326 people
- Sponsor
- Sanofi
AORTIC VALVE DISEASES, Mitral Valve Failure
Advanced Robotic Beds for the Early Rehabilitation of Cardiac Surgery Patients
The goal of this clinical trial is to evaluate whether LOLE.K, a new and specialized robotic bed, is effective in the rehabilitation of patients who have undergone surgery.
- Trial name
- CARE (NCT07273669)
- Testing
- use of the robotic bed
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- University of Salerno
Hemodilution, Coronary Artery Disease
Retrograde Autologous Priming and Mannitol for Reducing Hemodilution in Cardiac Surgery
Hemodilution reduces concentrations of blood constituents: concentration of hemoglobin, red blood cells (hematocrit), physiological ions and coagulation factors that can contribute to impaired hemostasis and increasing the risk…
- Conditions
- Hemodilution, Coronary Artery Disease, Fluid Overload
- Trial name
- RAPPER-MAN (NCT04870073)
- Testing
- Retrograde autologous priming, Mannitol, Conventional Priming
- Where
- Canada
- Sponsor
- Hamilton Health Sciences Corporation
Atrial Fibrillation, Inflammatory Marker
Red Cell Distribution Width as a Predictor for Post Operative Atrial Fibrillation After Open Heart Surgries
In this study we investigate the correlation between RDW and POAF, as we use the RDW as a predictor for inflammation for prediction of POAF
- Conditions
- Atrial Fibrillation, Inflammatory Marker, Heart; Surgery, Heart, Functional Disturbance as Result
- Trial name
- NCT06286111
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Transposition of Great Vessels, Surgery
MRI Study After Arterial Switch Operation in Patients With Transposition of the Great Arteries
This study involves adolescents operated with arterial switch procedure for transposition of the great arteries during the neonatal period.
- Trial name
- NCT01916499
- Testing
- 3 tesla magnetic resonance imaging findings; coronary artery status, 3 tesla magnetic resonance imaging findings; ventricular function and morphology
- Where
- Norway
- Volunteers
- 70 people
- Sponsor
- Oslo University Hospital
Atrial Fibrillation, Ischemic Heart Disease
Epicardial Fat Pads Ablation During Coronary Surgery
The aim of this prospective randomized study was to assess the efficacy of ablation of the ganglionated plexi localized in the epicardial fat pads for preventing recurrences of atrial tachyarrhythmia in patients with paroxysmal…
- Trial name
- NCT02984371
- Testing
- Coronary artery bypass grafting, Epicardial ganglionated plexi ablation, implantable loop recorder
- Where
- 2 sites in Russia
- Volunteers
- 264 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Aneurysm Aortic, Vascular Diseases
F-BEVAR vs Open Surgery for Complex Abdominal Aortic Aneurysm
The aim of the present study was to investigate outcomes of a propensity matched series of patients treated with F-BEVAR and open surgery repair for complex abdominal aortic aneurysm in two aortic high-volume centres.
- Trial name
- NCT05247944
- Testing
- Fenestrated and branched endovascular aortic repair (F-BEVAR), Open repair
- Volunteers
- 278 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Heart Defects, Congenital, Hypertension, Pulmonary
Intravenous L-Citrulline to Treat Children Undergoing Heart Bypass Surgery
This clinical trial will determine the safety and effectiveness of intravenous L-citrulline in children undergoing cardiopulmonary bypass during heart surgery.
- Trial name
- NCT00335244
- Testing
- L-citrulline
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Asklepion Pharmaceuticals, LLC
Tricuspid Regurgitation
Surgical Treatment of Tricuspid Valve Regurgitation in Patients With Cardiac Implantable Electronic Devices: Long Term Results
Old trials aimed to evaluate Implantable Cardioverter-Defibrillator (ICD) safety and efficacy demonstrated a meaningful decreased rates of sudden death but an increased rate of hospitalization for heart failure .
- Trial name
- NCT05774821
- Testing
- Tricuspid valve surgery
- Where
- Italy
- Volunteers
- 151 people
- Sponsor
- Michele De Bonis
Low Flow Anesthesia, High Flow Anesthesia
Effects of Different Fresh Gas Flows on Carboxyhemoglobin Levels and Postoperative Patient Outcomes in Pediatric Cardiovascular Surgery
Low flow anesthesia; It is an anesthesia practice in which, after absorbing at least 50% of the exhaled air and carbon dioxide (CO2) using a semi-closed rebreathing system, the unused anesthetic gases are mixed with a certain…
- Trial name
- NCT06097806
- Testing
- low and high flow
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
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