Clinical trials: Cardiovascular System
Healthy Volunteers
Cardiovascular Health Arterial Stiffness Raspberry and Microbiome (CHARM)
In this study, the investigators aim to determine the health benefits of red raspberry ellagitannin consumption on cardiovascular health.
- Trial name
- CHARM (NCT04087278)
- Testing
- Red Raspberry Ellagitannin Extract
- Where
- United Kingdom
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- King's College London
Embolic Stroke of Undetermined Source
Identification of New Markers of Atrial Myopathy in Patients With Embolic Stroke of Undetermined Source (ESUS) From MRI 4D Data
Atrial myopathy is considered to be the underlying cause of a large proportion of embolic strokes of undetermined source. However, the definition of this atrial condition is not well delineated while its identification could lead…
- Trial name
- IRM 4D-AVC (NCT04717843)
- Testing
- 4D Flow MRI, Medical consultation with 12 leads ECG, Holter ECG
- Where
- 3 sites in France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Gamification, Nutrition
Usability and Feasibility of the NutriQuest Application
The study is a pilot study (phase 2) that includes a usability study (phase 1). The aim of the study is to investigate the feasibility and usability of the healthy nutrition application and the effects on adherence to Modified…
- Conditions
- Gamification, Nutrition, Behavior Change
- Trial name
- NCT05884489
- Testing
- A gamified smartphone app-based eating behaviour intervention
- Where
- Belgium
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Jessa Hospital
Cardiovascular Disease
The Role of Nitric Oxide Synthase in Circulating Progenitor Cell Function
Our main hypothesis is that EPC function is impaired in some populations with high cardiovascular risk as a result of reduced eNOS-dependent NO production.
- Trial name
- NCT00627068
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Macular Holes, Epiretinal Membrane
Intraoperative OCT Guidance of Intraocular Surgery II
The overall five-year goals of the project are to develop novel technology to provide actionable new information through provision of live volumetric imaging during surgery, improving surgical practice and outcomes.
- Conditions
- Macular Holes, Epiretinal Membrane, Diabetic Retinopathy, Retinal Detachment
- Trial name
- MIOCT (NCT03713268)
- Testing
- Microscope integrated optical coherence tomography
- Where
- United States
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Duke University
Prediabetes, Hypertension
Intervention With a GABA Supplement in Prediabetics
In this double-blind parallel placebo controlled intervention study the effects of 3 times daily 500 mg gamma-aminobutyric acid (GABA) supplementation on glucose tolerance and cardiovascular health will be assessed in…
- Trial name
- NCT04303468
- Testing
- GABA
- Where
- Netherlands
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Physical Fitness, Health Knowledge
"11 for Health" in Pakistan - Effects on Physical Fitness, Health Knowledge and Well-being of 8-14-year-old Schoolchildren
This study examined the effects of a school-based football intervention, the "11 for Health" (11fH) programme, on cardiorespiratory health, musculoskeletal fitness, health knowledge and well-being among Pakistani school children.
- Conditions
- Physical Fitness, Health Knowledge, Cardiovascular Health, Well-being
- Trial name
- NCT07542574
- Testing
- "11 for Health" Intervention Programme
- Where
- Pakistan
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Farman Ullah
Complication Due to Immunization
Cardio-respiratory Events and Inflammatory Response After Primary Immunization in Preterm Infants
Background: Inflammation may depress respiration in neonates. The aim of this study was to establish a link between post-immunization inflammation and cardio-respiratory events (CRE).
- Trial name
- NCT02726178
- Testing
- Advil® Pediatric drops for infants
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Multiple Myeloma
Multiple Myeloma and Environmental Exposure to Pesticides in the French West Indies: A Population Based Case-control Study.
Multiple myeloma (MM) is a malignancy of plasma cells engaging in monoclonal immunoglobulin production. A strong presumption was established between exposure to pesticides and the risk of MM.
- Trial name
- MYELODOM (NCT04260490)
- Where
- 2 sites in Guadeloupe, Martinique
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Guadeloupe
Stroke, Acute
The Effectiveness of Waiting Room Posters for Stroke Education
The purpose of this study is to determine the effectiveness of posters in improving patient awareness and knowledge of the signs and symptoms of stroke. The control group study will be conducted in the first two weeks.
- Trial name
- NCT03391713
- Testing
- Poster
- Where
- Malaysia
- Volunteers
- 1,064 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Hyperlipidemias, Inflammation
The Effects of Homogenized and Unhomogenized Milk on Postprandial Metabolism in Healthy Overweight Men
The purpose of this study is to compare the effects of homogenized, unhomogenized and skimmed milk on postprandial metabolism in healthy overweight men
- Conditions
- Hyperlipidemias, Inflammation, Atherosclerosis
- Trial name
- NCT01317524
- Testing
- Homogenized milk, Unhomogenized milk, Skimmed Milk
- Where
- Netherlands
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Hypertension
Glu298Asp Polymorphism and Blood Pressure
The Glu298Asp polymorphism has been linked to increased risk of cardiovascular events, proposed to be due to reduced nitric oxide production by eNOS reported in some but not all studies.
- Trial name
- NCT02037308
- Testing
- Bread
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Reading
Brain Tumor, MRI
Brain Diseases on 7.0T Magnetic Resonance Imaging
This clinical trial studies the use of 7-Tesla (7T)and 3T magnetic resonance imaging (MRI) in detecting brain diseases. 7T MRI has increased detection sensitivity, including more accurate lesion delineation, higher inter-rater…
- Conditions
- Brain Tumor, MRI, Cerebrovascular Disease
- Trial name
- NCT05287750
- Testing
- Magnetic resonance imaging
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Genetic Predisposition to Disease
AHC Ballana Heart Study
This Study is designed to assess CVD incidence, prevalence, progression and related risk factors, including genetic background. It will provide an important base for all cardiovascular research activities in our centre and help…
- Trial name
- AHC-BHS (NCT05661318)
- Testing
- Risk assessment
- Where
- Egypt
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Magdi Yacoub Heart Foundation
Diabetes Mellitus, Type 1
Cardiovascular Autonomic Neuropathy in Patients With Type 1 Diabetes Mellitus.
testing of autonomic function and relationship with exercise and Qol in diabetic patients and controls
- Trial name
- NCT03481374
- Testing
- autonomic function testing
- Where
- Belgium
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Stroke
Neuroplastic Change in Myelin of the Brain
The main goal of this research is to advance understanding of how stroke changes both the structure and function of the brain. The investigators will determine which is the key driver of recovery of arm function after stroke…
- Trial name
- Myelin (NCT01937910)
- Testing
- TRAIT Task
- Where
- Canada
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Atrial Fibrillation, Catheter Ablation
Post-Ablation Pericarditis Reduction Study
There has not been a prospective, randomized controlled trial of colchicine to reduce post-AF ablation pericarditis in an era of newer AF ablation techniques.
- Conditions
- Atrial Fibrillation, Catheter Ablation, Pericarditis
- Trial name
- PAPERS (NCT04906720)
- Testing
- Colchicine
- Where
- United States
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- St. Vincent Cardiovascular Research Institute
Hypotension, Labor Complication
Pre-epidural Sequential Compression Devices (SCDs) to Prevent Hypotension During Labor
When hypotension is related to epidural placement, this can occur within 15-60 minutes after placement. The purpose of this study is to build upon this preliminary work and to use a randomized controlled trial to examine the…
- Trial name
- NCT05250960
- Testing
- SCD
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- TriHealth Inc.
Stroke, Acute
Timed Interval Measurement of Eotaxin in Stroke Study
Stroke is caused by sudden changes in blood flow in the brain. This can be fatal or can result in permanent disability. A fast diagnosis is essential to initiate effective interventions and optimize benefits to patients.
- Trial name
- TIMES (NCT03521882)
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Diabetic Foot, Diabetes
Predictors of Skin Temperature, Plantar Pressure and Ulceration in Diabetic Foot Patients.
Diabetes is a chronic disease with increasing prevalence worldwide with a high burden to individuals and the society and it is expected to be the 7th leading cause of death in 2030.
- Trial name
- NCT03254095
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
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