Clinical trials: Care-resistant Behavior
Hypoglycemia
Glucagon Ready-to-Use (RTU) for Prevention of Exercise-Induced Hypoglycemia During Aerobic Exercise in Adults With T1D
This study is a randomized, placebo-controlled, double-blind, 2-treatment, 2-period, crossover comparison in a clinical research center (CRC) setting, followed by a randomized, placebo-controlled, double-blinded, 2-arm parallel…
- Trial name
- NCT03841526
- Testing
- Glucagon RTU Injection With Insulin Pump Reduction, Vehicle for Glucagon RTU Injection With Insulin Pump Reduction, Glugaon RTU Injection Without Insulin Pump Reduction
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Xeris Pharmaceuticals
Helicobacter Pylori Infection, Compliance, Patient
Comparison of Bismuth Containing Quadruple Therapy and Based Tailored Therapy for H. Pylori Infection
As the antibiotic resistance increases, the eradication rate of triple therapy is decreasing. Recent guideline recommend the use of bismuth-containing quadruple therapy in areas where clarithromycin resistance is greater than…
- Conditions
- Helicobacter Pylori Infection, Compliance, Patient, Drug Resistance, Antibiotics
- Trial name
- NCT03361267
- Testing
- Helicobacter pylori PCR test, CLO test
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Inha University Hospital
Preoperative Care, Anxiety
Use of Maltodextrins in the ERAS Preoperative Fasting Protocol in Pediatric Surgery
This monocentric prospective randomized controlled pilot study aims to evaluate the effectiveness of preoperative maltodextrin administration within an Enhanced Recovery After Surgery (ERAS) protocol in pediatric surgical…
- Conditions
- Preoperative Care, Anxiety, Pediatric Surgery
- Trial name
- ERAS-MALTO (NCT07686029)
- Testing
- Maltodextrin Clear Liquid, Non-Sugared Clear Liquid
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
Psychotic Disorders
Improving Heart and Metabolic Health in People With Severe Mental Illness Through a Long-term Clinical Trial
Background Cardiometabolic conditions-including cardiovascular disease, type 2 diabetes, and obesity-are highly prevalent among individuals with psychotic disorders.
- Trial name
- LAGOM (NCT06781801)
- Testing
- Intervention
- Where
- 6 sites in Sweden
- Volunteers
- 650 people
- Sponsor
- Vastra Gotaland Region
Depression
Halifax Treatment Refractory Depression Trial
This study will use a randomized parallel group design to examine the effects of Intensive Short-term Dynamic Psychotherapy (ISTDP) for depressed patients non-remitting following at least one course of antidepressants.
- Trial name
- NCT01141426
- Testing
- Intensive Short-term Dynamic Psychotherapy, Secondary Care Treatment as Usual
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Joel Town
Type 2 Diabetes
Diabetes Prevention in Clinical Practice.
We randomize individuals with impaired glucose tolerance to one of three arms for degree of physical activity: 1. Continue with your current life style; 2. Ordinary life activities for increased physical activity; 3.
- Trial name
- DIAVIP (NCT01834378)
- Testing
- Low intensity intervention, High intensity intervention.
- Volunteers
- 96 people
- Sponsor
- Göteborg University
Coronary Artery Disease, Acute Coronary Syndrome
Genotyping Infarct Patients to Adjust and Normalize Thienopyridine Treatment
The objective of GIANT Study is to evaluate the clinical impact of genetic resistance to thienopyridine profile determination (CYP2C19 gene) and the clinical impact of compliance to an adjusted thienopyridine treatment on STEMI…
- Conditions
- Coronary Artery Disease, Acute Coronary Syndrome, Genetic Resistance to Clopidogrel, Compliance to Thienopyridine Treatment
- Trial name
- GIANT (NCT01134380)
- Where
- 12 sites in France
- Volunteers
- 1,500 people
- Sponsor
- Biotronik France
Self-harm Behavior, Eating Disorders
Evaluation of National Highly Specialized Care for Adults With Treatment-Resistant Self-Harm and Eating Disorders: Substudy 1
This study aims to evaluate National Highly Specialized Care (NHV) for adults with severe and treatment-resistant self-harm or eating disorders in Sweden.
- Conditions
- Self-harm Behavior, Eating Disorders, Non-suicidal Self-injury (NSSI)
- Trial name
- NHV_ADULTS (NCT07878897)
- Testing
- National Highly Specialized Care (NHV)
- Where
- 2 sites in Sweden
- Volunteers
- 250 people
- Sponsor
- Karolinska Institutet
Hypertension, Metabolic Syndrome
Hypertension And Surgery Study: Evaluating the Implementation of a Hypertension Guideline Protocol
HASS-2 is a multi-center, cross-sectional quality improvement project: evaluating the implementation of a hypertension guideline protocol by perioperative clinicians, as a model for improving various aspects of public health.
- Conditions
- Hypertension, Metabolic Syndrome, Non-Compliance, Medication
- Trial name
- HASS-2 (NCT03921086)
- Testing
- Antihypertensive medication according to the study's algorithm
- Where
- 7 sites in South Africa
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Cape Town
Health Behavior, Physical Activity
Enjoyment Mediates Long-term Changes in Physical Activity Level in a Physical Activity on Prescription Intervention.
A sufficient level of physical activity (PA) positively affects health and longevity. In Swedish healthcare, insufficiently physically active patients are offered physical activity on prescription (PAP) treatment, an individual…
- Conditions
- Health Behavior, Physical Activity, Metabolic Syndrome, Primary Health Care
- Trial name
- NCT06749249
- Volunteers
- 444 people
- Sponsor
- Vastra Gotaland Region
Cystitis Acute, Antibiotic Resistant Infection
Dipsticks and Microscopy to Reduce Antibiotic Use in Women's Urinary Tract Infections: a Pilot Trial (MicUTI)
With the aim to pilot a full-scaled trial to reduce unnecessary antibiotics in women with suspected uncomplicated urinary tract infections, twenty general practices in Bavaria, Germany, will be randomized to deliver patient…
- Conditions
- Cystitis Acute, Antibiotic Resistant Infection, Medication Adherence, Urinary Tract Infection Bacterial
- Trial name
- MicUTI (NCT05667207)
- Testing
- Point-of-care microscopy and dipstick guided management
- Where
- 2 sites in Germany
- Volunteers
- 154 people
- Sponsor
- Wuerzburg University Hospital
Tuberculosis, Drug-resistant Tuberculosis
An Evaluation of Traditional Directly Observed Therapy (DOT) and Electronic DOT for TB Treatment
This study is a U.S.-based, 1 site (with 4 clinical settings), randomized controlled trial (with funding from the Centers for Disease Control and Prevention's (CDC) Antibiotic Resistance Solutions Initiative) that will be…
- Conditions
- Tuberculosis, Drug-resistant Tuberculosis, Adherence, Medication, Adherence, Patient
- Trial name
- NCT03266003
- Testing
- Electronic DOT, In-person DOT
- Where
- 4 sites in United States
- Volunteers
- 216 people
- Sponsor
- Centers for Disease Control and Prevention