Clinical trials: Care-resistant Behavior, open to volunteers
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Phase I Randomized Controlled Trial of Functional Resistance Training in Older Cancer Survivors: The ACES Trial
The study will assess the feasibility and preliminary efficacy of live, online supervised group functional resistance training in older cancer survivors who may have difficulty with independent functioning.
- Conditions
- Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm, Cancer, Functional Limitation
- Trial name
- ACES (NCT07606313)
- Testing
- Functional Resistance Training, Stretching, Delayed Functional Resistance Training
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- OHSU Knight Cancer Institute
Stress Resilience, Stress
Strengthening Health Literacy in Healthcare Workers Through Mind Body Medicine and Nutrition
This is a randomized controlled trial aiming to develop and evaluate a workplace health program to improve stress resilience and mental well-being among healthcare workers at University Medicine Essen using a participatory…
- Conditions
- Stress Resilience, Stress, Burnout, Burnout Syndrome
- Trial name
- SOULFOOD (NCT07255313)
- Testing
- SOULFOOD Programme
- Where
- Germany
- Volunteers
- 252 people
- Sponsor
- Universität Duisburg-Essen
Malaria
Factors Influencing Adoption of a Novel Malaria Treatment in Côte d'Ivoire, Ghana, and Rwanda
This non-interventional qualitative study will examine factors that influence the adoption of a novel malaria treatment in Côte d'Ivoire, Ghana, and Rwanda.
- Trial name
- NCT07896746
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
Obesity Prevention, Weight Change
Optimizing an Extended Care Intervention to Promote Weight Loss Maintenance
The purpose of this study is to find out what combination of components, if any, offers the best support for keeping weight off after someone loses weight.
- Conditions
- Obesity Prevention, Weight Change, Weight Loss, Weight Loss Maintenance
- Trial name
- OPT-X (NCT06785064)
- Testing
- Reduced Food Variety (RFV), Home-based Resistance Training (HBRT), Buddy Training and Support (BTS)
- Where
- United States
- Volunteers
- 544 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
External Snapping Hip, Coxa Saltans External
Progressive Resistance Training for Adults With External Snapping Hip
External snapping hip is characterised by an audible and painful snap during hip movement among physical active people around 15-40 years old.
- Trial name
- Snappy Hip (NCT06924164)
- Testing
- Progressive resistance training, Waiting time, Self guided exercise
- Where
- 13 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Aarhus University Hospital
Perioperative Care, Intermittent Fasting
Intermittent Fasting Versus Carbohydrate Drinks Before Surgery
The purpose of this study is to investigate whether time-restricted feeding, a form of intermittent fasting, before surgery improves insulin resistance around the time of surgery, compared to carbohydrate drinks and standard…
- Conditions
- Perioperative Care, Intermittent Fasting, Carbohydrate Loading, Preoperative Fasting
- Trial name
- PRINCESS (NCT05760339)
- Testing
- Time-restricted feeding, Carbohydrate loading
- Where
- Netherlands
- Volunteers
- 75 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Colorectal Cancer, Colorectal Neoplasms
Resistance vs Aerobic Prehabilitation Before Colorectal Cancer Surgery
The goal of this clinical trial is to learn which type of exercise before surgery best reduces complications after colorectal surgery in adults with colorectal cancer or precancerous lesions.
- Conditions
- Colorectal Cancer, Colorectal Neoplasms, Postoperative Complications
- Trial name
- NCT07896174
- Testing
- Resistance Training Prehabilitation, Aerobic Training Prehabilitation, Standard Trimodal Care
- Where
- Hungary
- Volunteers
- 480 people
- Sponsor
- Semmelweis University
Diabetes Mellitus, Type 2, Obesity
"Effectiveness of Supervised and Unsupervised mHealth-based Exercise Interventions on Clinical Outcomes in Adults With Type 2 Diabetes and Obesity Within a Primary Care Context"
Type 2 diabetes (T2D) and obesity are two of the most common chronic conditions worldwide, and they frequently occur together. Both conditions are closely linked to physical inactivity, which is currently recognized as a major…
- Conditions
- Diabetes Mellitus, Type 2, Obesity, Insulin Resistance, Sedentary Behaviors
- Trial name
- NCT07685080
- Testing
- Supervised Exercise Training Program, mHealth Unsupervised Exercise Program (ActiVital App), Wearable Device Monitoring (Fitbit Charge 6)
- Where
- Spain
- Volunteers
- 126 people
- Sponsor
- Escuela Universitaria de Osuna
HFpEF - Heart Failure With Preserved Ejection Fraction
HEART Camp Connect -Promoting Exercise in Adults With Heart Failure With Preserved Ejection Fraction
The goal of this study is to learn more about patients with heart failure with preserved ejection fraction (HFpEF) and exercise.
- Trial name
- NCT05784753
- Testing
- HEART Camp, HEART Camp Connect
- Where
- 3 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Antimicrobial Drug Resistance
A Complex Intervention to Promote Appropriate Antibiotic Use Among Rural Residents Based on the Metaphor-Embedded Integrated Behavioral Model
The study aims to address the question of how to provide effective health education on health topics with high medical specialisation (e.g.
- Trial name
- NCT06967766
- Testing
- health education based on the Metaphor-Embedded Integrated Behavioral Model
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Bo Yan
Resistant Hypertension, Medication Adherence
Heart Rate Variability and Medication Adherence in Resistant Hypertension
This single-center, cross-sectional observational study examines the relationship between adherence to antihypertensive therapy - verified objectively by therapeutic drug monitoring (TDM) - and heart rate variability (HRV) in…
- Conditions
- Resistant Hypertension, Medication Adherence, Autonomic Nervous System
- Trial name
- HRV-HYP-1 (NCT07707583)
- Testing
- Heart rate variability recording (Polar H10) ·, Therapeutic drug monitoring (antihypertensive drug levels), Questionnaires (MARS-CZ, PHQ-9, SF-36, IPAQ)
- Where
- Czechia
- Volunteers
- 150 people
- Sponsor
- Nemocnice AGEL Trinec-Podlesi a.s.
HIV Infections, AIDS
A Randomized Clinical Trial to Evaluate Solutions for the Management of Virologic Failure on TLD in Sub-Saharan Africa
The RESOLVE trial is an open, parallel arm, randomized clinical trial which aims to determine the optimal strategy for management of virologic failure on antiretroviral therapy (ART) with tenofovir, lamivudine, and dolutegravir…
- Conditions
- HIV Infections, AIDS, Virologic Failure
- Trial name
- RESOLVE (NCT05373758)
- Testing
- Standard of Care treatment strategy, Individualized Care treatment strategy, Immediate Switch
- Where
- 3 sites in South Africa, Uganda
- Volunteers
- 648 people
- Sponsor
- Massachusetts General Hospital
Self-harm Behavior, Eating Disorders
Evaluation of National Highly Specialized Care for Children and Adolescents With Severe Self-Harm or Eating Disorders
National Highly Specialized Care (NHV) is provided in Sweden to children and adolescents with severe and treatment-resistant self-harm or eating disorders when previous treatment has not led to sufficient improvement.
- Conditions
- Self-harm Behavior, Eating Disorders, Non-suicidal Self-injury (NSSI)
- Trial name
- NHV_CHILD (NCT07898059)
- Testing
- National Highly Specialized Care (NHV)
- Where
- 2 sites in Sweden
- Volunteers
- 120 people
- Sponsor
- Karolinska Institutet
Treatment-Resistant Major Depressive Disorder
Understanding Music and Mindfulness Preferences in Psilocybin-Assisted Psychotherapy
The goal of this pilot clinical trial is to learn whether it is feasible to individually tailor psilocybin-assisted psychotherapy (PAP) for people with treatment-resistant depression (TRD) based on their personal preferences.
- Trial name
- PPP (NCT07373535)
- Testing
- Psilocybin 25mg, Music-centered psilocybin-assisted therapy, Mindfulness-centered psilocybin-assisted therapy
- Where
- 2 sites in Canada
- Volunteers
- 16 people
- Sponsor
- Kyle Greenway
Health Services Accessibility, Rural Health
Health Ahead Comparative Effectiveness Study
The Health Ahead Comparative Effectiveness Study is a pragmatic, parallel-arm interventional platform that systematically compares successive changes to preventive health screening on the path toward a fully automated screening…
- Conditions
- Health Services Accessibility, Rural Health, Medically Underserved Area, Preventive Health Services
- Trial name
- HACE (NCT07669168)
- Testing
- AI-Assisted Screening Interpretation (AI Reads), Human-Only Screening Interpretation
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- William Brandenburg, MD
Distal Radius Fracture, Colles Fracture
Wrist Injury Strengthening Exercise (WISE) Versus Usual Care Advice for Improving Pain and Function
The goal of this clinical trial is to find out whether a therapist-guided exercise program helps people aged 50 and older recover better, in terms of pain and function, after a wrist fracture, compared to the usual care advice…
- Conditions
- Distal Radius Fracture, Colles Fracture, Wrist Fracture, Wrist Fractures
- Trial name
- WISE-DK (NCT07538323)
- Testing
- Supervised Exercise, Usual Care
- Where
- Denmark
- Volunteers
- 588 people
- Sponsor
- University of Aarhus
Preoperative Care, Anxiety
Use of Maltodextrins in the ERAS Preoperative Fasting Protocol in Pediatric Surgery
This monocentric prospective randomized controlled pilot study aims to evaluate the effectiveness of preoperative maltodextrin administration within an Enhanced Recovery After Surgery (ERAS) protocol in pediatric surgical…
- Conditions
- Preoperative Care, Anxiety, Pediatric Surgery
- Trial name
- ERAS-MALTO (NCT07686029)
- Testing
- Maltodextrin Clear Liquid, Non-Sugared Clear Liquid
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
Psychotic Disorders
Improving Heart and Metabolic Health in People With Severe Mental Illness Through a Long-term Clinical Trial
Background Cardiometabolic conditions-including cardiovascular disease, type 2 diabetes, and obesity-are highly prevalent among individuals with psychotic disorders.
- Trial name
- LAGOM (NCT06781801)
- Testing
- Intervention
- Where
- 6 sites in Sweden
- Volunteers
- 650 people
- Sponsor
- Vastra Gotaland Region
Self-harm Behavior, Eating Disorders
Evaluation of National Highly Specialized Care for Adults With Treatment-Resistant Self-Harm and Eating Disorders: Substudy 1
This study aims to evaluate National Highly Specialized Care (NHV) for adults with severe and treatment-resistant self-harm or eating disorders in Sweden.
- Conditions
- Self-harm Behavior, Eating Disorders, Non-suicidal Self-injury (NSSI)
- Trial name
- NHV_ADULTS (NCT07878897)
- Testing
- National Highly Specialized Care (NHV)
- Where
- 2 sites in Sweden
- Volunteers
- 250 people
- Sponsor
- Karolinska Institutet