Clinical trials: Caries, Dental
Smoking, Obesity
TEACH: Technology Evaluation to Address Child Health
The proposed study is a pre- /post-implementation study in a pediatric practice with a control practice designed to test the feasibility and effectiveness of an electronic screening and service delivery tool for three modifiable…
- Conditions
- Smoking, Obesity, Dental Caries
- Trial name
- TEACH (NCT02912000)
- Testing
- TEACH intervention
- Where
- United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Dental Caries
Preventive Effect of a Probiotic Tablet on Oral Health in Preschool Children
The aim of the prospective project is to investigate effect of daily probiotic supplements on dental caries development in preschool children living in a low socioeconomic immigrant area in souithern Sweden.
- Trial name
- NCT01720771
- Testing
- probiotic tablet, sugar pill
- Where
- Sweden
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Initial Dental Caries
Remineralizing Effect of Nano-eggshell, Casein Phosphopeptide Amorphous Calcium Phosphate (CPP-ACP), and Sodium Fluoride on Initial Enamel Caries
This randomized controlled clinical trial aims to evaluate and compare the remineralizing effect of nano-eggshell varnish, CPP-ACP paste (GC Tooth Mousse), and sodium fluoride varnish on initial enamel caries among adolescents…
- Trial name
- CPP-ACP (NCT07711132)
- Testing
- nano-eggshell varnish, Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP)Dental Paste, Sodium Fluoride Varnish (5%)
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Mansoura University
Initial Dental Caries
Dentifrice With Innovative Remineralizing Technology
Objective: The aim of this study is to evaluate in vivo dentifrices containing different active ingredients in fluoride (F) retention in saliva and dental biofilm.
- Trial name
- REFIX (NCT04730908)
- Testing
- DENTIFRICE
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federal University of Paraíba
Dental Caries, Tooth Demineralization
"Comparison of the Effects of Resin Infiltrant, Fluoride Varnish, and the Combined Application of Resin Infiltrant and Fluoride Varnish on Primary Molars in the Treatment of Proximal Non-Cavitated Carious Lesions in Children."
Purpose: This randomized controlled clinical trial aimed to compare the effectiveness of fluoride varnish, resin infiltrant, and their combination in treating superficial proximal carious lesions in primary molars of children…
- Conditions
- Dental Caries, Tooth Demineralization, Pediatric Dentistry, Molar, Deciduous
- Trial name
- NCT07112963
- Testing
- Fluoride Varnish
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Sacide Duman
Dental Caries (Diagnosis), Artifical Intelligence
Accuracy Of Detection Of Dental Caries From Intraoral Images Using Different ArtificiaI Intelligence Models
The goal of this observational study is to evaluate the diagnostic accuracy of different deep learning models in detecting dental caries from intra oral images taken by a professional intra oral camera in children.
- Conditions
- Dental Caries (Diagnosis), Artifical Intelligence, Intraoral Images
- Trial name
- NCT06749743
- Testing
- FASTER RCNN
- Where
- Egypt
- Volunteers
- 398 people
- Sponsor
- Cairo University
Dental Caries, Dental Plaque
Study of the Composition of Dental Plaque
This study will examine the composition of dental plaque-a naturally occurring substance that sticks to the teeth and can cause tooth decay and gum disease.
- Conditions
- Dental Caries, Dental Plaque, Periodontal Disease
- Trial name
- NCT00001726
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Caries,Dental
Fluoride Caries-control Effectiveness/Feasibility in Children
The aim of this study is to compare the effectiveness and feasibility of using silver diamine fluoride solution (SDF) vs. sodium fluoride varnish (NaF) for caries management in children from Bogotá (and its suburban areas) and…
- Trial name
- NCT06690008
- Testing
- Experimental group
- Where
- 2 sites in Colombia
- Volunteers
- 814 people, healthy volunteers welcome
- Sponsor
- Universidad El Bosque, Bogotá
Early Childhood Caries
Happy Teeth for Hopi Tots: Cultural Adaptation of an Oral Health Entertainment-Education Intervention
Tooth decay is a preventable disease occurring at high rates among American Indian (AI) populations. The use of entertaining educational materials and cultural adaptation have shown success in improving health behaviors.
- Trial name
- NCT05297526
- Testing
- Culturally adapted children's book, Standard informational brochure on children's oral health
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northern Arizona University
Caries of Infancy, Dental Anxiety
Intranasal Sedation With Dexmedetomidine and Ketamine in Pediatric Dentistry (NASO II)
Parallel clinical trial focusing on procedural pediatric sedation in the dental setting. Children will be randomized to treatment according to a predetermined sequence of interventions consisting of: 1.
- Trial name
- NCT03290625
- Testing
- Dexmedetomidine Hydrochloride, Ketamine Hydrochloride
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Primary Dental Caries
Effects of Partical Excavation in One Versus Two Procedures of Primary Deep Caries (PAPRICA)
Background: Deep caries is the most frequent reason for performing root canal treatments. Minimally invasive methods for the treatment of deep carious lesions might therefore be relevant to avoid pulp exposures and consequently…
- Trial name
- PAPRICA (NCT03696498)
- Testing
- Resin restoration (1 step), Resin restoration (2 steps)
- Where
- 11 sites in Denmark, Lithuania and 2 more
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Dental Caries in Children
A Comparative Clinical and Radiographic Study Of Collagen Based Pulpotomy in Cariously Exposed Vital Primary Molars
To assess post operative pain and survival rate after collagen based pulpotomy versus MTA pulpotomy in children with vital primary molars.
- Trial name
- NCT05829304
- Testing
- MTA based pulpotomy, Collagen based pulpotomy
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- sherouk atef elsayed
Class V Dental Caries
Two Year Clinical Performance of Ion-releasing and Non Ion-releasing Composite Restorative Systems in Restoring Cervical Carious Lesions.
The goal of this clinical trial is to learn if ion releasing composite materials works to induce remineralization of caries affected dentin in adults.
- Trial name
- NCT07849426
- Testing
- Ion-releasing resin composite, Giomer based composite, Non-ion-releasing ormocer based composite
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Dental Caries
Stopping Cavities Study: Diammine Silver Fluoride
This study is being conducted to test whether the use of diammine silver fluoride (also called silver diamine fluoride) hardens the cavity sufficiently so that it arrests.
- Trial name
- NCT02536040
- Testing
- 38% diammine silver fluoride, Water
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Advantage Dental Services, LLC
Class II Dental Caries
Comparative Clinical Evaluation Between a Novel Self Adhesive and Conventional Bulk-fill Composites
This study aimed to evaluate the clinical performance of a novel, tooth-colored, self-adhesive bulk-fill restorative, and a conventional bulk-fill composite, for restoring class II cavities.
- Trial name
- NCT06120868
- Testing
- Surefil one®, Filtek One
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Nourhan M.Aly
Decayed Teeth
Custom-made Versus Prefabricated Zirconia Crowns for Primary Molars.
Background: Do construction methods of pediatric zirconia crowns affect the periodontal health and clinical performance of badly decayed primary molars? The question asked by many practitioners.
- Trial name
- NCT04620174
- Testing
- Custom-made zirconia crowns, Prefabricated zirconia crowns
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Al-Azhar University
Dental Caries
Evaluation of Ion Releasing Hybrid Restorative Material
Esthetic and mechanical evaluation of calcium and phosphate releasing hybrid restorative material and fluoride releasing hybrid restorative material versus the conventional nanofilled resin composite in proximal carious lesions…
- Trial name
- NCT04854655
- Testing
- Conventional resin composite, Activa Presto, Giomer
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Glass Ionomer Sealant and Fluoride Varnish Study to Prevent Early Childhood Caries
The goal of this project is to conduct a community-based randomized clinical trial to compare the caries prevention efficacy of fluoride varnish applied every six months vs.
- Trial name
- GIFVT (NCT01129440)
- Testing
- Fluoride Varnish, Glass Ionomer Sealant
- Where
- United States
- Volunteers
- 597 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Dental Caries, Dental Adhesive Materials
Clinical Performance of Bioactive Restorative Materials
The aim of this clinical study is to evaluate the performance of three different bioactive restorative materials against a composite resin for a period of 9 months.
- Trial name
- Bioactive (NCT07394751)
- Testing
- Tetric N Ceram Bulkfill application, Cention Forte application, Stela Automix
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ege University
Deep Caries
Deep Marginal Acquisition With Thermacut Bur Vs. Functional Crown Lengthening in Deep Carious Lesions
this clinical trial is conducted to compare between deep marginal acquistion by the means of thermacut bur Vs. functional crown lengthening in exposing deep subgingival interproximal cervical lesions
- Trial name
- NCT06205459
- Testing
- deep marginal acquisition using thermacut bur
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
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