Clinical trials: Caries; Dentin
Carious Lesion
Efficacy of Nanoparticle-incorporated Bonding Agent on Post-restorative Sensitivity
Type of study: Randomized Clinical trial To compare post-restorative sensitivity between titania nanoparticle reinforced bonding agent and bonding agent without nanoparticles in posterior composite restorations.
- Trial name
- NCT05744648
- Testing
- Composite resin restoration using Titania nanoparticle reinforced bonding agent, Composite resin restoration without Titania nanoparticle incorporated bonding agent
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Dental Caries in Children
Partial or Complete Excavation of Deep Caries in Primary Molars
Background: The traditional approach of carious lesions with risk for progression has has been to excavate all infected and demineralised tissue before placement of the restoration.
- Trial name
- PBRN (NCT04614285)
- Testing
- Partial excavation
- Where
- Sweden
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Dental Caries
Use of Antibacterial Cement in Infected Dentin
Dental materials with antibacterial properties can prevent the harmful effects caused by oral cariogenic bacteria. This double-blind controlled clinical trial evaluated the performance of antibacterial cement for sealing infected…
- Trial name
- AC (NCT01449136)
- Testing
- Antibacterial cement
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- University of Pernambuco
Dental Caries Extending Into Dentin, Root Caries
Root Caries Excavation with Air Water/powder Prophylaxis Device for ART Restorations
The main objective of this RCT is to compare the efficacy of a powder/water jet prophylaxis device and conventional hand excavation in excavating root surface caries, with regard to restoration survival/success in older adults.
- Trial name
- ART-AIRFLOW (NCT04822246)
- Testing
- Control: Hand instrumentation for caries excavation, Intervention 1: EMS Airflow device for caries excavation, Intervention 2: Hand excavation + EMS Airflow device for caries excavation
- Where
- Switzerland
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Murali Srinivasan, Dr. med. dent., BDS, MDS, MBA, MAS
Dental Caries, Secondary Dental Caries
Influence of the Number of Layers of a One Bottle Adhesive on the Longevity of Composite Restorations in Primary Molars
The aim of this study is to determinate the influence of an alternative adhesive application protocol (i.e. consecutive application of an extra adhesive layer)on restoration longevity in primary molars.
- Trial name
- NCT01680289
- Testing
- Three adhesive coats, Two adhesive coats
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Carious Dentin
Postoperative Hypersensitivity and Digital Radiographic Assessment of a Zinc Modified Versus a Conventional Glass Ionomer Cement in Deep Carious Lesion: Randomized Controlled Clinical Trial
The study aim to evaluate the difference between the effect of zinc modified glass ionomer and conventional glass ionomer on the success of partial caries removel technique
- Trial name
- NCT03285022
- Testing
- Partial caries removel techniques
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Evaluation Of Fluoride Uptake By Dentine Following Silver Diamine Fluoride Under Resin Modified Glass Ionomer Restoration In Carious Primary Molars
Dental caries is one of the most common oral diseases of childhood and is considered as a major public health problem especially in areas with poor access to dental care.
- Trial name
- NCT04777968
- Testing
- Silver diamine fluoride
- Where
- 2 sites in Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Laser, Tooth
Efficacy of Er,Cr:YSGG Laser in Partial Pupotomy
The aim of this study was to compare the efficacy of partial pulpotomy treatment using MTA and Er,Cr:YSGG + MTA in permanent immature molar teeth with deep dentin caries.
- Conditions
- Laser, Tooth, Pulpotomy
- Trial name
- NCT04010929
- Testing
- Partial pulpotomy with laser+MTA, Partial pulpotomy with MTA
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Merve Erkmen Almaz
Caries,Dental, Sensitivity, Tooth
Post-operative Sensitivity in Resin Composites
This triple-blind, randomized clinical trial was conducted at the department of Operative dentistry. A total of 60 participants were recruited and were randomly distributed into two groups A and B.
- Trial name
- NCT06242184
- Testing
- Group A(Nano-fortified Adhesive), Group B(Adhesive without nanoparticles)
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Primary Dental Caries
Effects of Partical Excavation in One Versus Two Procedures of Primary Deep Caries (PAPRICA)
Background: Deep caries is the most frequent reason for performing root canal treatments. Minimally invasive methods for the treatment of deep carious lesions might therefore be relevant to avoid pulp exposures and consequently…
- Trial name
- PAPRICA (NCT03696498)
- Testing
- Resin restoration (1 step), Resin restoration (2 steps)
- Where
- 11 sites in Denmark, Lithuania and 2 more
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Dental Caries
Partial Removal of Caries Dentines
The aim of this multicenter randomized controlled clinical trial is to evaluate the effectiveness of an alternative treatment for deep caries lesions in Public Health Services.
- Trial name
- PRCD (NCT00887952)
- Testing
- Partial removal of carious dentine, Stepwise excavation
- Where
- 2 sites in Brazil
- Volunteers
- 329 people
- Sponsor
- Federal University of Rio Grande do Sul
Deep Caries Lesion of Pemanent Teeth
Outcome of Selective Caries Removal Performed by Undergraduate Students
Deep tooth decay can sometimes reach very close to the nerve of a tooth. Traditionally, dentists may remove all of the decayed tooth tissue, but removing too much tissue can increase the risk of exposing or damaging the nerve.
- Trial name
- NCT07765810
- Testing
- Selective caries removal to soft dentine, Selective Caries Removal to Firm/Leathery Dentine
- Where
- Jordan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Class I Cavities in High Caries Risk, Class I Composite Restorations
The Clinical Performance of Two Dentine Replacement Materials in Deep Occlusal Cavities (Randomized)
Higher mechanical properties are needed to restore structurally compromised posterior teeth, short fiber reinforced resin composite and injectable bioactive resin composites provide superior properties to flowable composites that…
- Conditions
- Class I Cavities in High Caries Risk, Class I Composite Restorations, Randomized Clinical Trial, Occlusal Caries
- Trial name
- NCT06924047
- Testing
- Beautifil Flow Plus X, EverX Flow
- Volunteers
- 50 people
- Sponsor
- Dalia Sameh Fawzi
Restoration, Caries; Dentin
Composite Restorations in Primary Molars
The aim of this study was to compare the clinical performance of direct restorations with two different indirect composite systems in primary teeth.
- Conditions
- Restoration, Caries; Dentin, Caries Class Ii
- Trial name
- Composite Rest (NCT07761897)
- Testing
- Fédération Dentaire Internationale (FDI) criteria., survival comparison
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Dental Caries in Children
Potential for Dentine Discoloration of Silver Diamino Fluoride Associated With Potassium Iodide
The objective of this randomized clinical trial will be the comparison of dentine discoloration after treatment with: Silver Diamino Fluoride and Silver Diamino Fluoride associated with Potassium Iodide for caries lesions in…
- Trial name
- NCT04001959
- Testing
- Silver Diamine Fluoride with Potassium Iodide
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federal University of the Valleys of Jequitinhonha and Mucuri
Caries; Dentin, Dental Restoration Failure of Marginal Integrity
Absence of Liner Following the Selective Caries Removal (ALFSCaRe)
This randomized, multi-centric, controlled clinical trial will assess the effectiveness of a simplified restorative protocol used after the selective carious tissue removal in posterior teeth presenting deep carious lesions.
- Trial name
- (ALFSCaRe) (NCT03933176)
- Testing
- Restoration of carious lesions
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Universidade Federal de Sergipe
Dental Caries
Postoperative Pulpal Complications in Posterior Resin Composite Restorations Without Glass-ionomer Cement Lining
The purpose of this study is to observe the effects of glass-ionomer cement (GIC) lining on risk of pulpal complications in deep occlusal cavities with resin-based restorations.
- Trial name
- NCT01567514
- Testing
- Glass ionomer cement lining
- Where
- Thailand
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Dental Caries
Pre-etching of Dentin Before Restorations With High Viscosity Glass Ionomer Cement
The objective of this randomized clinical trial is to evaluate the survival of restoration with high viscosity glass ionomer cement (HVGIC) with pre-etching with polyacrilic acid compared with no pre-etching in order to treat…
- Trial name
- CEPECO4 (NCT03785769)
- Testing
- HVGIC restoration with pre-etching, HVGIC restoration with non pre-etching
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Universidade Ibirapuera
Caries, Dental
Management of Occlusal Dentinal Caries in Deciduous Molars
This study evaluated and compared the efficacy of no caries removal and sealing with a well-adapted and crimped stainless steel crown verses selective caries removal upto soft dentin and upto firm dentin in healing and/or…
- Trial name
- MOD (NCT03552835)
- Testing
- no caries removal, partial caries removal upto soft dentin, partial caries removal upto firm dentin
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sneha D. Suwarnkar
Indirect Pulp Cap
A Study Comparing Eggshell Based and Gold Standard Materials to Heal Deep Tooth Damage in Adult Molars
This clinical trial will evaluate the effectiveness of eggshell-derived calcium hydroxyapatite compared to calcium hydroxide as indirect pulp capping agent in permanent teeth.
- Trial name
- NCT07183514
- Testing
- eggshell-derived calcium hydroxyapatite, Calcium hydroxide
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- University of Health Sciences Lahore