Clinical trials: Caries; Dentin
Deep Caries, Pulp Exposure, Dental
Selective Removal to Soft Dentine vs Selective Removal to Firm Dentine for Deep Posterior Caries Lesions
Removal of infected dentin contaminated with bacteria and remaining affected dentin detected as firm is the conventional strategy for the management of cavitated caries lesions.
- Conditions
- Deep Caries, Pulp Exposure, Dental, Dental Caries
- Trial name
- NCT04052685
- Testing
- Selective removal to soft dentin (SRSD), Selective removal to firm dentine (SRFD)
- Where
- Turkey (Türkiye)
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- burcu gözetici
Dentin Caries
Evaluation of the Remineralizing and Antibacterial Effect of Natural Versus Synthetic Materials on Deep Carious Dentin
The present study will be performed to evaluate: 1. The remineralizing effect of natural materials versus synthetic materials on deep carious dentin after selective caries removal. 2.
- Trial name
- NCT04145102
- Testing
- hesperidine, propolis, silver diamine fluoride
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Dental Caries, Hydroxyapatite
Caries-preventing Effect of a Hydroxyapatite-toothpaste in Adults
Target question is as the following one: Does the daily use of a fluoride-free, microcrystalline hydroxyap-atite (HAP) - containing test toothpaste have a non-inferior caries preventing effect in the permanent dentition compared…
- Conditions
- Dental Caries, Hydroxyapatite, Tooth Decay, Dentin, Carious
- Trial name
- CA1 (NCT04756557)
- Testing
- Experimental., Active comparator
- Where
- Poland
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Poznan University of Medical Sciences
Deep Dental Caries
Attitude and Practice for Deep Caries Management Between Egyptian and Indian Dentists : a Cross Sectional Study
Study type: Observational Study To assess and compare the attitudes, and practices of dentists in Egypt and India regarding the removal of deep dentin caries and preferred restorative strategies.
- Trial name
- NCT06806254
- Where
- Egypt
- Volunteers
- 766 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Er,Cr:YSGG Laser Versus Conventional Preparation for Minimally Invasive Caries Removal
This study compared two standard methods for minimally invasive caries removal in children: conventional mechanical excavation and Er,Cr:YSGG laser preparation.
- Trial name
- NCT07493278
- Testing
- Mechanical Caries Removal, Er,Cr:YSGG Laser Caries Removal
- Where
- Bulgaria
- Volunteers
- 32 people
- Sponsor
- Medical University of Sofia
Caries; Dentin, Caries Class II
Clinical Performance of Fiber-Reinforced Dentin Replacement Materials
the current study was conducted to evaluate and compare the flowable short fiber-reinforced (SFRC) and flowable bulk-fill resin composites (BFCs) regarding their 4-year clinical performance as dentin replacement materials in…
- Trial name
- NCT07320885
- Testing
- Ever x flow, SDR, Tetric N-Flow Bulk fill
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Mansoura University
Dentin Bridge, Pulpitis
Partial Pulpotomy on Caries Free Human Teeth
The purpose of this study is to compare the human pulp response to partial pulpotomy using White ProRoot MTA or iRoot BP in the terms of dentinal bridge formation and inflammation.
- Trial name
- NCT01420718
- Testing
- MTA, iRoot BP
- Where
- Iran
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Caries, Dental Pulp Exposure
Calcium Hydroxide, Mineral Trioxide Aggregate and Biodentine (Trademark) as Direct Pulp Capping of Permanent Teeth
Background: Dental caries is considered an oral health problem worldwide. In Chile the last national epidemiological study (2007) showed a national prevalence of dental caries in children 6 years (70.3%) and 12 (62.5%).
- Trial name
- NCT02492841
- Testing
- Mineral trioxide aggregate, Calcium hydroxide, Biodentine
- Where
- Chile
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Dental Caries, Dental Caries in Children
Atraumatic Versus Silver-Modified Atraumatic Restorative Treatment in Primary Molars
The goal of this clinical trial is to evaluate and compare the short-term effectiveness of two minimally invasive treatments-Atraumatic Restorative Treatment (ART) and Silver-Modified Atraumatic Restorative Treatment (SMART)-in…
- Trial name
- NCT07023939
- Testing
- ART: Atraumatic restorative treatment, SMART: Silver-Modified Atraumatic Restorative Treatment
- Where
- Lebanon
- Volunteers
- 34 people
- Sponsor
- Beirut Arab University
Dental Caries, Dental Pulp Exposure
Stepwise and One Step Techniques In Deep Dentin Lesion
This double blind, randomized, controlled clinical trial aimed to observe the success of stepwise (SW) and one step (OneS) excavation techniques in the management of deep dentin caries.
- Trial name
- NCT04351048
- Testing
- Stepwise Excavation, One Step Excavation
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- TIJEN PAMIR
Caries; Dentin, Fissure, Dental
Sealing of Occlusal Dentin Caries in Primary Molars.
BACKGROUND A simple method for arresting dentin caries with a tight seal of the cavity would exclude the need for injection and excavation, reduce the risk for dental fear and possibly postpone or eliminate the need for further…
- Conditions
- Caries; Dentin, Fissure, Dental, Dental Caries in Children, Glass Ionomer Cement
- Trial name
- SealCar (NCT05475145)
- Testing
- Resin based sealing [RBS]
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Mats Bågesund
Deep Carious Lesions, Partial Caries Removal
This Study Aims to Clinically Assess and Radiographically Measure the Formed Dentin Bridge Over the Pulp, Utilizing Three-dimensional Imaging Following the Application of a Bioactive Restorative System Versus a Conventional Restorative System After Selective Caries Removal to Soft Dentin Over 2
This clinical trial aims to evaluate dentin bridge formation over the pulp following selective caries removal in permanent teeth with deep carious lesions (ICDAS scores 5-6).
- Conditions
- Deep Carious Lesions, Partial Caries Removal, Dentin Bridge
- Trial name
- NCT07171775
- Testing
- Experimental - Bioactive Restorative System, Active Comparator -Conventional Restorative System
- Volunteers
- 66 people
- Sponsor
- Cairo University
Dental Caries, Pulp Exposure, Dental
Clinical Study Evaluating Solventum™ Vitrebond™ Pulp Protect Liner/Base for Direct Capping of Pulpal Exposure
This research study is looking at the safety and effectiveness of Solventum™ Vitrebond™ Pulp Protect Liner/Base for direct pulp capping (DPC) on permanent teeth that have pulp exposure due either to deep cavities, trauma, or…
- Conditions
- Dental Caries, Pulp Exposure, Dental, Tooth Decay, Dental Decay
- Trial name
- NCT07231237
- Testing
- Vitrebond™ Pulp Protect Liner/Base
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Solventum US LLC
Remineralization Potential, Dentin Caries
Clinical Performance and Remineralization Potential of Self- Assembling Peptide P11-4 Containing Fluoride Versus Er, Cr: YSGG Laser Treatment and Micro Tensile Bond Strength of Giomer Restoration in Carious Lesions
This study will be performed in two parts, in vivo and in vitro to assess the effect of the remineralization potential of self-assembling peptide P11-4 containing Fluoride on caries-affected dentin compared to untreated…
- Trial name
- NCT07065305
- Testing
- Curodont Repair Fluoride Plus (Self-assembling peptide remineralization agent)P11-4 peptide, fluoride, mild acidic buffer (pH ~4.5) , Credentis AG, Switzerland, Beautifil II LS
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Dental Caries
Polymer Induced Liquid Precursor (PILP) in Adults in With Dentin Caries
The goal of this clinical trial is to learn if polymer-induced liquid precursor (PILP) can be used safely to treat dentin caries (cavities) in adults.
- Trial name
- NCT06727110
- Testing
- PILP Cement, PILP Conditioner
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
Partial Dentin Caries Removal
Radiographic Assessment of Glass Ionomer Restorations With and Without Prior Application of Nano Silver Fluoride in Occlusal Carious Molars Treated With Partial Caries Removal Technique
eligible teeth will be randomly divided into two groups to be treated with incomplete caries excavation (A), where (A1) represents teeth to be treated with application of Nano silver fluoride solution on remaining carious dentin…
- Trial name
- NCT03193606
- Testing
- nano silver fluoride solution
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Reversible Pulpitis, Pulpitis
Antibacterial Effect and Clinical Performance of Chitosan Modified Glass Ionomer
The study is a randomized clinical trial that assesses the clinical success and the antibacterial effect on carious dentine of glass ionomer when modified with Chitosan and/or Titanium dioxide nano particles vs the control group…
- Conditions
- Reversible Pulpitis, Pulpitis, Caries,Dental, Caries Class I
- Trial name
- NCT04365270
- Testing
- Glass Ionomer, Chitosan Low Molecular Weight (20-200 Mpa.S), Chlorhexidine Diacetate
- Where
- Egypt
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Deep Carious Lesions
Clinical Performance of Resin Composite Restoration After Dentin Biomodification by Grape Seed Extract in Deep Carious Lesions.
This study will evaluate the clinical and radiographic performance of resin composite restoration after utilized a grape seed extract as dentin biomodification in vital teeth with deep occlusal carious lesions (ICDAS 5-6) after…
- Trial name
- GSE (NCT06780527)
- Testing
- 15% Grape seed extract as dentin pretreatment
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Clinical Evaluation of Nanoionomer Filling in Primary Teeth
This clinical trial was performed to evaluate the nano-filled resin modified glass ionomer (RMGI) -with a brand name of "Ketac Nano"- as a filling material for the treatment of caries in primary teeth.
- Trial name
- CENFPT (NCT02093091)
- Testing
- Dental caries was removed from primary molars and was filled with the recent filling material; Ketac Nano., Dental caries was removed from primary molars and was filled with the conventional filling material;Vitremer
- Where
- Egypt
- Volunteers
- 29 people
- Sponsor
- Tanta University
Caries Roots, Flouride Varnish
Effectiveness Silver Diamine Fluoride Versus Sodium Fluoride in Arresting Caries Around Crown Margins in Older Adults
Dental caries is a multifactorial, progressive disease which is the major causes of dental pain, infection and tooth loss. Dental caries can substantially compromise the quality of life in older adults 1 2.
- Conditions
- Caries Roots, Flouride Varnish, Caries; Dentin, Caries Arrested
- Trial name
- NCT04255251
- Testing
- Silver Diammine Fluoride, Fluoride Varnishes
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of New England