Clinical trials: Caries
Decay, Dental
General Dentists' Knowledge, Attitudes and Clinical Usage of SDF
This study will look at how dentists in the UK are using Silver Diamine Fluoride (SDF) in their everyday practice. SDF is a liquid treatment that helps stop tooth decay.
- Trial name
- GDPKAUSDF (NCT07405437)
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Dental Caries, Dry Mouth
Oral Health Intervention in Adult Primary Care
This study is a Stage III cRCT to test the efficacy of multi-level interventions at the practice- and provider-level to address low dental utilization (attendance) among Medicaid-enrolled older adults 55 years or older attending…
- Conditions
- Dental Caries, Dry Mouth, Periodontal Diseases, Bleeding Gum
- Trial name
- NCT06555029
- Testing
- EHR Changes, Medical Staff EHR Training, Clinician CSM theory-based didactic education and skills training, Standard ADA Oral Health Training
- Where
- United States
- Volunteers
- 929 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Dental Caries
Oral Health Knowledge and Caries Experience in Adults
This cross-sectional study assessed the level of oral health knowledge and its relationship with caries experience, independently of age and sex, in adult patients attending a university dental clinic in Gran Canaria (Spain).
- Trial name
- NCT07881380
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Las Palmas de Gran Canaria
Dental Caries, Tooth Discoloration
Color Stability of Darkly Discolored Arrested Caries Lesions Following Bleaching Treatment
This observational study evaluated the color stability of darkly discolored arrested caries lesions (DDACL) on anterior teeth following in-office bleaching with 40% hydrogen peroxide, in comparison with healthy teeth.
- Trial name
- NCT07886255
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Dental Caries, Teeth Loss
The Effect of Bitewing Radiography on Outcomes and Costs of Treating Caries in Permanent Teeth
Dentists commonly use bitewing radiographs (dental X-rays) together with a visual-tactile (clinical) examination to detect cavities between the back teeth.
- Conditions
- Dental Caries, Teeth Loss, Necrosis of Pulp, Irreversible Pulpitis
- Trial name
- BROCC (NCT07882693)
- Testing
- Visual-tactile caries examination, Visual-tactile caries examination and bilateral bitewing radiography
- Where
- Finland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Jukka Leinonen
Dental Anxiety, Dental Fear
Dental Anxiety in Children Attending Emergency Versus Routine Dental Care
The goal of this observational study is to learn whether children who come to a pediatric dental emergency clinic have higher dental anxiety than children who come for routine dental care.
- Trial name
- NCT07882914
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Marmara University
Dental Caries in Children, Dental Plaque
Targeting of Preventive Treatment for Adolescents at Risk of Oral Diseases
The aim of the study is to identify adolescent patients that are at risk of developing oral diseases, and to assess if targeted preventive oral treatment with antibacterial dual-light therapy as an adjunctive treatment method can…
- Conditions
- Dental Caries in Children, Dental Plaque, Tooth Decay, Periodontitis
- Trial name
- LumoPrevent (NCT06286501)
- Testing
- Lumoral Treatment, Standard, personalized oral health care
- Where
- Finland
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Wellbeing Services County of Pirkanmaa
Periodontal Diseases, Dental Caries
Prevalence of Caries and Periodontal Disease and Their Correlation in a Dental School in Egypt
In Egypt, oral diseases such as caries and periodontal disease are particularly burdensome, with implications for overall health and quality of life.
- Trial name
- NCT07880808
- Testing
- Prevalence of caries and periodontal diseases
- Where
- Egypt
- Volunteers
- 369 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Is Xylitol Toothpaste Effective in Preventing Tooth Decay?
The study will identify children at high caries risk and provide their parents/caregivers with evidence-based, risk-based at-home preventive measures for their infants, including daily use of xylitol or fluoride toothpaste.
- Trial name
- NCT04096599
- Testing
- Xylitol toothpaste, Fluoride toothpaste
- Where
- China
- Volunteers
- 579 people, healthy volunteers welcome
- Sponsor
- Dr. Gillian Lee
Dental Caries Class II
Evaluation of Clinical Success of Bulk Fil Composite Versus Highly Viscous Glass Ionomer in Primary Class II Molars
evaluate the clinical performance of EQUIA Forte ® ( a HVGIC) and Plafique® Bulk Flow composite resin when placed in class II cavities in primary molars.
- Trial name
- NCT06235489
- Testing
- Palfique Bulk Flow
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Prevention of Dental Caries
Effect of Bioactive Glass Varnish on Salivary Parameters in Children: Randomized Controlled Trial
This study is a two-arm parallel randomized controlled trial led by Principal Investigator Inas Karawia at the Faculty of Dentistry, designed to evaluate and compare the short-term (immediatly) and sustained (over 6 months)…
- Trial name
- NCT07875387
- Testing
- Bioactive glass topical varnish, Fluoride varnish
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pharos University in Alexandria
Dental Caries, Tooth Injuries
Luting Cements for Prefabricated Zirconia Crown Retention in Primary Anterior Teeth in Children
The goal of this clinical trial is to compare the long-term clinical performance of three different luting cements used to bond prefabricated zirconia crowns (PZCs) on primary front teeth in young children.
- Conditions
- Dental Caries, Tooth Injuries, Primary Tooth Restoration
- Trial name
- NCT07611734
- Testing
- Cementation with Fuji IX GP Extra Glass Ionomer Cement, Cementation with BioCem™ Universal BioActive Cement, Cementation with RelyX™ Universal Resin Cement
- Where
- Saudi Arabia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Murad Alrashidi
Dental Caries; Oral Health; Malocclusion
Dental Caries and Related Factors in 6-Year-Old Schoolchildren in Chile: National Evidence for Assessment and Decision-Making (6yOH-Chile)
Dental caries is the most prevalent chronic non-communicable disease in childhood worldwide. In Chile, the last nationally representative oral health survey was conducted in 2007 and reported a caries experience prevalence of…
- Trial name
- 6yOH-Chile (NCT07863947)
- Where
- Chile
- Volunteers
- 2,484 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Dental Caries
Clinical Study 3MESPE Crowns CR15/02
This clinical study seeks to address four independent questions that are all part of the delivery of care associated with the provision of a single item of treatment; an indirect restoration (known as a 'crown') to restore and…
- Trial name
- NCT02735304
- Testing
- Impression intervention
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Caries, Erosive Tooth Wear
New In Situ Model Design for Caries and Erosion
This study will test simultaneously and independently two novel in situ models, one for caries and one for erosive tooth wear (ETW), based on the simulation of these dental conditions on enamel specimens placed on 3D-printed…
- Trial name
- NCT07849270
- Testing
- 0 ppm fluoride toothpaste, 250 ppm fluoride toothpaste (dose-response control), 1150 ppm fluoride toothpaste
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Indiana University
Pain, Dental Caries
Comparison of Intraosseous Anesthesia and Inferior Alveolar Nerve Block for Primary Mandibular Molars
The aim of the present study is to compare computerized intra-osseous injection system to the conventional inferior alveolar nerve block in primary mandibular teeth.
- Trial name
- NCT07846098
- Testing
- Inferior Alveolar Nerve Block, intraosseous anaesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Early Childhood Caries
Povidone Iodine Efficacy Study
This is a single center, randomized, double-blind, placebo-controlled Phase II clinical trial (RCT) to evaluate the efficacy of topical 10% Polyvinylpyrrolidone-Iodine (PVPI) to prevent new caries lesions when applied to the…
- Trial name
- PIES (NCT05272254)
- Testing
- 10% povidone iodine + FV
- Where
- United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Caries,Dental
Efficacy of a Chitosan Dressing in Pulpotomy of Immature Permanent Teeth
Immature permanent teeth, also known as young permanent teeth, are used to describe teeth with incomplete root formation. Immature permanent teeth are prone to caries and trauma which can cause exposure and degeneration of pulp.
- Trial name
- NCT07323433
- Testing
- Chitosan Dressing
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Minia University
Deep Caries
Clinical and Radiographic Success Rate of Pulpotomy Versus Pulpectomy for Management of Primary Teeth With Deep Caries
This trial aims to compare treatment outcomes between Pulpotomy and Pulpectomy in treating vital primary teeth diagnosed with deep caries with symptoms of irreversible pulpits
- Trial name
- NCT06293521
- Testing
- Pulpotomy, Partial Pulpectomy
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Er:YAG Laser for Dental Cavity Preparation
The goal of this clinical trial is to compare Er:YAG laser cavity preparation with conventional rotary instruments in adults who have permanent premolars planned for extraction as part of orthodontic treatment.
- Trial name
- NCT07831720
- Testing
- Er:YAG Laser, Conventional Rotary Cavity Preparation
- Where
- Vietnam
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ho Chi Minh City Odonto-Stomatology Hospital