Clinical trials: Carious Cervical Lesions
Tooth Sensitivity
Non-carious Cervical Lesions and Treatments
This study will compare clinically the efficacy, time to action and duration of different treatments for patients with non-carious cervical lesions (NCCLs) that caused dentin hypersensitivity (DH).
- Trial name
- NCCL (NCT03403088)
- Testing
- Experimental: • Group LA, Experimental: • Group DE, Experimental: • Group RGI
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Class V Non-carious Cervical Dental Lesions
Impact of Dentin Pretreatment With Dimethyl Sulfoxide on Behavior of Resin Composite Restorations in Non-Carious Cervical Lesions
the aim of this study to evaluate and compare the impact of dimethyl sulfoxide dentin surface pretreatment on the performance of composite restorations in non-cervical carious lesions
- Trial name
- NCT07830641
- Testing
- Dimethyl sulfoxide (DMSO), NO dimethyl sulfoxide
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Cervical Lesion
Clinical Evaluation of Bulk-fill Alkasite Restoration Versus Resin Modified Glass Ionomer in Adult With Class V Carious
Cention N will have the same clinical performance as resin-modified glass ionomer in cervical carious lesions. Evaluation of restorations will be done at baseline, six months, and one year according (USPHS) criteria.
- Trial name
- NCT04716517
- Testing
- Alkasite bioactive restorative material., Resin Modified Glass Ionomer
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Non-carious Cervical Lesions
Release of Organic Components of a GIOMER in Non-carious Cervical Lesion Restorations
To evaluated the clinical performance of composite resin restorations, considering also the evaluation of release of resin components into saliva and the presence cytokines in gingival fluid.
- Trial name
- NCT03637946
- Testing
- Device: SHOFU beautifil II LS
- Where
- Brazil
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Non-carious Cervical Lesions
Evaluation of the Solvent Evaporation Time of Universal Adhesives in the Quality of Cervical Lesions Restorations
The aim of this study will be to evaluate the effect of prolonging solvent evaporation time on the 6- and 12-months clinical performance of two universal adhesive systems used as selective enamel etch (SEE).
- Trial name
- NCT05945173
- Testing
- Evaporation time for 5 seconds, Evaporation time for 25 seconds, alcohol/water-based universal adhesive
- Where
- Chile
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Tooth Diseases
Clinical Evaluation of Three Different Universal Adhesives in Non-carious Cervical Lesions
The aim of this randomized, controlled prospective clinical trial is to evaluate and compare the performances of three different universal adhesives using a flowable universal composite resin in the restoration of non-caries…
- Trial name
- NCT03415412
- Testing
- Clearfil Univesal Bond, IBond Universal, G-Premio Bond
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dentin Desensitizers, Non-carious Cervical Lesions
Effect of an Experimental Gel Based on Acmella Oleracea Extract Associated or Not With Fluoride on Dentin Hypersensitivity
This randomized, single-blind, placebo-controlled clinical trial aims to evaluate the effect of an experimental gel based on Acmella oleracea (jambú) extract, associated or not with fluoride, in reducing dentin hypersensitivity…
- Conditions
- Dentin Desensitizers, Non-carious Cervical Lesions, Dentin Hypersensitivity
- Trial name
- NCT06971783
- Testing
- CT- control group, NP- Potassium nitrate gel, AO - Acmella Oleracea Extract Gel
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Universidade Federal do Para
Class V Non-carious Cervical Dental Lesions
Scotchbond Universal Plus Compared to Scotchbond Universal With Filtek Universal Restorative to Restore Class V NCCLs
This is a prospective, controlled, within-subject, randomized, single-center study comparing Scotchbond Universal Plus (SBU+) and Scotchbond Universal (SBU) adhesives when used with Filtek restorative.
- Trial name
- SBU+ClassV (NCT05361746)
- Testing
- Scotchbond Universal Plus Adhesive, Scotchbond Universal Adhesive
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Solventum US LLC
Tooth Restoration
Evaluation of Self-adhesive Hybrid Resin Composite Compared to a Traditional Composite Resin in Restorations of NCCLs
This is a split-mouth randomized clinical investigation conducted to evaluate clinical performances of a self-adhesive hybrid resin composite (investigational medical device Surefil) compared to a traditional composite resin…
- Trial name
- NCT05751382
- Testing
- Surefil one, Venus Pearl
- Where
- Italy
- Volunteers
- 16 people
- Sponsor
- Dentsply Sirona Implants and Consumables
Non-Carious Cervical Lesions
36-Month Clinical Evaluation of a Universal Adhesive
The aim of this clinical trial was to evaluate and compare the performance of a universal adhesive with different adhesive strategies in the restoration of non-carious cervical lesions (NCCLs) over a 36-month period.
- Trial name
- NCT03932929
- Testing
- Scotchbond Universal Adhesive (3M ESPE)
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Non-carious Cervical Lesions
Chlorhexidine as Coadjuvant in Dentin Adhesion of Noncarious Cervical Lesions
This study aims to evaluate the effect of chlorhexidine digluconate (CRX) application in etched dentin on the retention of noncarious cervical lesions restorations.
- Trial name
- NCT01947192
- Testing
- Treatment with chlorhexidine, Water pre-treatment
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Hypersensitivity Dentin, Tooth Hypersensitivity
Effectiveness of Bioactiveglass Air Abrasion Versus Fluoride Varnish in Management of Dentin Hypersensitivity
Will the use of Bioactive glass with air abrasion technology (Sylc) compared to Fluoride Varnish (Biflourid 10) affects the degree of pain in patients complaining from hypersensitivity due to non-carious lesions?
- Trial name
- NCT03285360
- Testing
- Sylc, fluoride varnish (Bifluorid 10)
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Composite Restorations, Tooth Lesions
Clinical Evaluation Of A New Two-Component Self-Etch Universal Adhesive
This randomized clinical trial evaluates the clinical performance of a new two-component self-etch universal adhesive, OptiBond XTR, when applied in non-carious Class V cervical lesions without macromechanical retention…
- Trial name
- XTR (NCT01464996)
- Testing
- Adhesive: OptiBond XTR; Composite: Herculite Ultra, Adhesive: OptiBond FL; Composite: Herculite Ultra
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Non Carious Cervical Lesion
Effect of an Additional Hydrophobic Adhesive Layer Application on the Class V Composite Restorations
In restorative dentistry, to enhance bond strength between dentin and simplified adhesive systems, new materials or applications are constantly being developed all the time.
- Trial name
- NCT05635981
- Testing
- Clearfil Majesty ES-2 Resin Composit Application to Non-carious Cervical Lesions
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Anxiety, Stress
Assessment of Risk Factors in Patients With Non-carious Cervical Lesions
In the management of patients with noncarious cervical lesions (NCCL), we observe that they frequently present signs of anxiety, traumatic brushing, bruxism or eating disorders.
- Conditions
- Anxiety, Stress, Non-carious Cervical Lesions
- Trial name
- LACIS (NCT06364020)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Dentin Hypersensitivity, Non-carious Cervical Lesions, Gingival Recession Localized Moderate
Polymeric Nano Calcium Fluoride Varnish, Diode Laser, and Their Combination for Dentin Hypersensitivity
The aim of the study is to assess the effect of polymeric nano calcium fluoride Varnish (Oli-NANO seal), 976 nm diode laser solely and combination of both therapies in the treatment of dentin hypersensitivity
- Trial name
- NCT07418788
- Testing
- Olinano seal, Diode Laser, Olinano seal and Diode Laser
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Faculty of Dental Medicine for Girls
Non-carious Cervical Lesions
Evaluation of the Reduced Dentin Etching Time Using Universal Adhesives in the Quality of Cervical Lesions Restorations
The aim of this study will be to evaluate the effect of reduced dentin etching time on the 6- and 12-months clinical performance of two universal adhesive systems used as etch-and-rinse application mode in non-carious cervical…
- Trial name
- NCT06465849
- Testing
- Dentin Etching time for 5 seconds, Scotchbond Universal Plus; 3M, Gluma Universal Bond; Kulzer
- Where
- Chile
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Non-carious Cervical Lesion
Prevalence of Non-Carious Cervical Lesions in Patient With Gingival Recession and Associated Risk Factors
The study aims at determining the prevalence of non carious cervical lesions in patients with gingival recession in Egyptian population and associated risk factors including gingival biotype, keratinized tissue width, gingival…
- Trial name
- NCT05170529
- Where
- Egypt
- Volunteers
- 362 people, healthy volunteers welcome
- Sponsor
- Cairo University
Carious Cervical Lesions
Self-Cure vs. Highly Filled Flowable Composite in Carious Cervical Lesions: 18-Month RCT
The aim of the study is to compare and evaluate the clinical performance of a self cure composite system versus a highly filled flowable composite in the restoration of carious cervical lesions over an 18 months follow up period.
- Trial name
- NCT07576673
- Testing
- Class V Restoration - Polofil, Class V Restoration - Stela
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Dentin Hypersensitivity
Effect of Diode Laser on Sensitive NCCLs Prior to Composite Restoration, Dentin Bonding, and Clinical Durability of Composite Restorations.
This study will investigate the efficacy of three diode laser wavelengths 445 nm, 660 nm, 970 nm when applied just before placement of composite restoration on reducing postoperative sensitivity from Non-carious cervical lesions…
- Trial name
- NCT05501691
- Testing
- 445 nm Diode Laser Wavelength, 660 nm Diode Laser Wavelength, 970 nm Diode Laser Wavelength
- Where
- Egypt
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Alexandria University