Clinical trials: Carious Lesion
Dental Caries Class v
Evaluation of the Marginal Integrity of Recent Bulk Fill Flowable Composite vs Glass Ionomer for Carious Cervical Restorations: RCCT
The study will be conducted to assess the marginal integrity of different types of restorations (ketac ™ N100 - ketac™ Universal and bulk fill flowable composite) in class v restoration using USPHS criteria.
- Trial name
- NCT04053530
- Testing
- restorative materials
- Where
- 2 sites in Egypt
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Cairo University
Postoperative Nausea and Vomiting, Sore-throat
Do Throat Pack Used in Dental Treatments Under General Anesthesia of Patients Have an Effect on PONV and Sore Throat?
The aim of this study is to investigate the effect of throat packs on PONV in dental treatments under general anesthesia in special health care needs.
- Conditions
- Postoperative Nausea and Vomiting, Sore-throat, Dental Caries
- Trial name
- NCT06169306
- Testing
- throat pack
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Discoloration, Tooth
Effect of Glutathione vs KI in Reducing SDF Staining When Used in Treatment of Primary Carious Teeth
Although black staining is considered a drawback that is clinically observed following SDF application and is the main primary barrier for its use clinically .
- Trial name
- NCT04816487
- Testing
- Potassium Iodide or Glutathione
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dentin Hypersensitivity, Non-carious Cervical Lesions, Bioactive Glass Air Polishing, S-PRG, Dentin Hypersensitivity
Effectiveness of Resin-Based Desensitizer and Laser, Compared to Fluoride Varnish in Management of Dentine Hypersensitivity in Non-carious Cervical Lesions
84 patients who fulfill the inclusion criteria will be enrolled to the study. For every patient a tooth of complain which fulfill the inclusion criteria will be selected, so the total number of included teeth will be 84 teeth.
- Conditions
- Dentin Hypersensitivity, Non-carious Cervical Lesions, Bioactive Glass Air Polishing, S-PRG, Dentin Hypersensitivity, Dentin Desensitizing Agents, Desensitization
- Trial name
- NCT07113847
- Testing
- Resin-Based Desensitizer, Laser Desensitizer, Fluoride-Based Desensitizer
- Where
- Egypt
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Early Childhood Caries (ECC), Dental Caries Prevention
Evaluating the Effect of Xylitol Wipes on Cariogenic Bacteria in Infants and Toddlers
This clinical study evaluates whether cleaning infants' and toddlers' teeth and gums with xylitol-containing wipes can help reduce oral bacteria associated with early childhood caries.
- Conditions
- Early Childhood Caries (ECC), Dental Caries Prevention, Oral Bacterial Colonization, Pediatric Oral Health
- Trial name
- NCT07245433
- Testing
- Xylitol Dental Wipes
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Dental Caries
Effect of the Amount of Fluoride Toothpaste on Fluoride Availability in the Oral Fluids in Children
The aim of the study is to determine the fluoride availability in saliva and dental biofilm after the use of increasing amounts of fluoride toothpaste.
- Trial name
- NCT03455621
- Testing
- Toothbrushing
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Caries,Dental
Caries Detection With Two Different Caries Detecting Devices
The primary aim of this study will be to compare the effectiveness of the novel LumiCare™ rinse and with QLF in determining caries progression.
- Trial name
- NCT06152081
- Testing
- LumiCare rinse, QLF Inspektor Pro Imaging
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tufts University
Preterm Birth, Periodontal Disease
Saving Lives at Birth: Primary Prevention of Periodontal Disease in Relation to Preterm Birth in Malawi
The hypothesis of the investigators' project is that comprehensive primary preterm birth prevention, inclusive of maternal oral health with xylitol chewing gum (the intervention), will reduce the rate of periodontal disease and…
- Conditions
- Preterm Birth, Periodontal Disease, Caries, Dental
- Trial name
- PPaX (NCT02333227)
- Testing
- Xylitol gum
- Where
- United States
- Volunteers
- 10,069 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Dental Caries, Unsatisfactory or Defective Restoration of Tooth
Clinical Evaluation of a Bulk Fill Resin Composite
The purpose of this clinical trial is to measure the clinical outcomes of Tetric PowerFill Class I and II restorations cured in 3 seconds with the Bluephase PowerCure curing unit.
- Trial name
- NCT04686422
- Testing
- Tetric PowerFill
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Ivoclar Vivadent AG
Dental Caries
Clinical Performance of Bioactive Highly Filled Injectable Flowable Composite for Direct Posterior Occlusal Conservative Restorations Using FDI Criteria: Two Year Randomized Clinical Trial
The aim of this study is to evaluate Clinical Performance of bioactive highly filled injectable flowable composite for direct posterior occlusal conservative restorations using FDI Criteria
- Trial name
- NCT06790511
- Testing
- bioactive highly filled injectable flowable composite, highly filled injectable flowable composite
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Patients With Deep Carious Lesions, Deep Caries Lesion of Pemanent Teeth
A Comparative Clinical Study Assessing Dentin Thickness and Discoloration in Deep Carious Lesions Treated With Biodentine Alone Versus Diode Laser Pre-treatment Followed by Biodentine
This interventional clinical study aims to compare dentin thickness preservation and tooth discoloration in deep carious lesions treated with Biodentine alone versus diode laser pre-treatment followed by Biodentine.
- Conditions
- Patients With Deep Carious Lesions, Deep Caries Lesion of Pemanent Teeth, Deep Carious Lesion
- Trial name
- NCT07358442
- Testing
- Biodentin, Diode laser
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Misr International University
Universal Adhesive
HEMA-free Universal Adhesives for Restoring Non-carious Cervical Lesions
because of the recent introduction of universal adhesives, little information is currently available about the bond durability of universal adhesives to various substrates.
- Trial name
- NCT05497583
- Testing
- Acetone based HEMA -free universal Adhesive, Isopropanol based HEMA- free universal Adhesive
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Caries Management by Risk Assessment in Children
The goal of this study is to address the effectiveness of a modified cavity prevention protocol for 5-9 year-old children which emphasizes better diet modification, more frequent professional fluoride applications, and xylitol…
- Trial name
- NCT01310283
- Testing
- xylitol mints and fluoride varnish
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Molar Incisor Hypomineralization, Dental Caries
Silver Diamine Fluoride and Papain-Based Gel for Management of MIH-affected Molar in Paediatric Patients
Molar incisor hypomineralization (MIH) is a developmental defect of enamel affecting the first permanent molar and frequently the incisors with a prevalence of 16-16.9% in Malaysia.
- Conditions
- Molar Incisor Hypomineralization, Dental Caries, Hypomineralization of Enamel
- Trial name
- NCT04710927
- Testing
- Silver Diamine Fluoride, Papain-Based Gel, High Viscosity Glass Ionomer Cement (HVGIC)
- Where
- Malaysia
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Dental Caries
The Children's Amalgam Trial
The Children's Amalgam Trial is one of only two randomized trials of its kind, and the only such trial in the United States, to address the potential impact of mercury exposure from amalgam restorations on neuropsychological and…
- Trial name
- NCT00065988
- Testing
- Dispersed phase amalgam restoration /composite restoration
- Where
- United States
- Volunteers
- 534 people
- Sponsor
- Carelon Research
Dental Caries
Preventing and Arresting Dental Root Surface Caries in Community-dwelling Older Adults
This study is a randomized clinical trial lasting for 30 months. A total of 300 subjects will be recruited from social centres for elders located in different districts in Hong Kong.
- Trial name
- NCT02360124
- Testing
- silver diammine fluoride, saturated potassium iodide solution
- Where
- China
- Volunteers
- 323 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Dental Caries
Chemomechanical Caries Removal Using Papain Gel
To evaluate the efficacy of a papain-based gel in caries removal.
- Trial name
- CMCR09 (NCT01811420)
- Testing
- Chemomechanical Caries Removal, Conventional method
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Caries,Dental
Efficacy of a Chitosan Dressing in Pulpotomy of Immature Permanent Teeth
Immature permanent teeth, also known as young permanent teeth, are used to describe teeth with incomplete root formation. Immature permanent teeth are prone to caries and trauma which can cause exposure and degeneration of pulp.
- Trial name
- NCT07323433
- Testing
- Chitosan Dressing
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Minia University
Pulpitis - Irreversible
Pulpotomy vs Root Canal Treatment for Teeth With Symptomatic Irreversible Pulpitis
This study is a randomised controlled trial for complete pulpotomy as an alternative to root canal treatment for teeth with clinical diagnosis of symptomatic irreversible pulpitis (i.e.
- Trial name
- NCT05964933
- Testing
- Complete Pulpotomy, Pulpectomy and Root Canal Treatment
- Where
- Singapore
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Dental Caries, Dental Pulp Exposure
Stepwise and One Step Techniques In Deep Dentin Lesion
This double blind, randomized, controlled clinical trial aimed to observe the success of stepwise (SW) and one step (OneS) excavation techniques in the management of deep dentin caries.
- Trial name
- NCT04351048
- Testing
- Stepwise Excavation, One Step Excavation
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- TIJEN PAMIR
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