Clinical trials: Carious Lesion
Pit and Fissure Sealants, Dental Caries Prevention
Dry-Shield vs Rubber Dam During Fissure Sealant Placement
This randomized clinical trial aims to evaluate the efficiency of the Dry-Shield isolation system compared with rubber dam isolation and cotton roll isolation during fissure sealant application in permanent molars among pediatric…
- Trial name
- DRY-SEAL (NCT07622173)
- Testing
- Pit and fissure sealant (Conseal F)
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Dental Caries in Children
Evaluation of Glass Ionomer Cement Modified With Chlorhexidine and Titanium Dioxide in Primary Molars (RCT)
to investigate the effect of modifying GIC with different formulations on the antibacterial activity and clinical performance in reference to unmodified glass ionomer restorative materials.
- Trial name
- NCT05645029
- Testing
- glass ionomer-chlorhexidine, glass ionomer-titanium dioxide powder, glass ionomer
- Where
- Egypt
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Permanent Molars, Dental Caries
Hall Technique vs Conventional Crown Restoration in Permanent Molars: Split-Mouth Trial in Children
The aim of this study is to compare the clinical and radiographic success of stainless steel crowns placed using the Hall Technique versus the conventional method in the restoration of permanent first molars in children, and to…
- Conditions
- Permanent Molars, Dental Caries, Tooth Decay, Permanent First Molar Caries
- Trial name
- HTCC-SM (NCT07186673)
- Testing
- Stainless steel crown placement using Hall Technique, Stainless steel crown placement using conventional method
- Where
- 2 sites in Syria
- Volunteers
- 10 people
- Sponsor
- Latakia University
Caries,Dental
Clinical Performance of Thermoviscous Bulk Fill Resin Composites in Comparison to Conventional Packable Bulk Fills
This clinical trial will be conducted to compare the clinical performance of the thermo-viscous preheated bulk fill composite in the management of carious lesions in posterior teeth in adult patients over 12 months.
- Trial name
- NCT05276154
- Testing
- thermoviscous bulkfill composite (Viscalor)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Minia University
Asthma, Dental Caries
Herbal Lollipops on Oral Bacterial Levels and DMFT/Dmft Scores of Children With Asthma Using Inhalers
Young children with asthma who use drugs for their asthma are at higher risk for tooth decay. These drugs can cause (1) dry mouth from less saliva secretion and (2) acid mouth that causes teeth to become soft and bacteria to…
- Trial name
- Lollipops (NCT01147835)
- Testing
- Chinese Licorice Root
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Dental Biofilm pH
In Vivo Study of Sucrose and Liquid Oral Pediatric Medicines of Long-term Effect on Dental Biofilm pH
The aims of this study were to determine the sucrose and liquid oral pediatric medicines of long-term effect on dental biofilm pH to evaluate the cariogenic potential in vivo.
- Trial name
- SPMedicines (NCT01819350)
- Testing
- G1, G2 and G3, G4 and G5
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Federal University of Paraíba
Class V Dental Caries
Clinical Performance Of Conserved Chalky White Demineralized Enamel Cavity Margins Versus Totally Removed Carious Margins In Class V Cavities Restored With Composite Resin
This study aims to compare the clinical performance of conserved chalky white demineralized enamel margins with total removal of demineralized enamel margins in class v cavities restored with composite in patients with acute…
- Trial name
- NCT05614076
- Testing
- conserved chalky white enamel margins of class V cavities, Total removal of demineralized enamel margins of class V cavities
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Cairo University
Dental Caries
Preventive Effect of a Probiotic Tablet on Oral Health in Preschool Children
The aim of the prospective project is to investigate effect of daily probiotic supplements on dental caries development in preschool children living in a low socioeconomic immigrant area in souithern Sweden.
- Trial name
- NCT01720771
- Testing
- probiotic tablet, sugar pill
- Where
- Sweden
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Dental Caries Tooth Demineralization, Post-Orthodontic Esthetic Defects
Evaluation of Self-assembling Peptides Versus Amorphous Calcium Phosphate in the Treatment of White Spot Lesions
This clinical trial aims to compare the effectiveness of two remineralizing treatments for white spot lesions (WSLs) on the enamel surfaces of the front teeth.
- Trial name
- NCT07146464
- Testing
- Self-Assembling Peptide P11-4 Self-Assembling Peptide P11-4 is a biomimetic material applied topically to white spot lesions on the enamel. It diffuses into the lesion body and forms a three-dimension
- Where
- Egypt
- Volunteers
- 18 people
- Sponsor
- Ain Shams University
Dental Caries
Composites and Urinary Bisphenol-A Study
The Composites and Urinary Bisphenol-A Study (CUBS) is a clinical study of dental composite for its effects on urinary bisphenol-A levels.
- Trial name
- CUBS (NCT01484132)
- Testing
- Restoration of dental caries with dental composite
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- Carelon Research
Dental Caries
Clinical Evaluation of Different Resin Composite Restorations
Posterior resin composite is challenging esthetic restoration. Patients seek for durable, esthetic and functional restorations in molars. one of the major problems is polymerization shrinkage.
- Trial name
- NCT05418400
- Testing
- sonic fill 3 & PALFIQUE bulk flow & Neo spectra & Clear fill AP-X
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Malnutrition, Child
Chronic Malnutrition and Oral Health Status in Children Aged One to Five Years
Malnutrition is a public health problem that can exert a negative impact on the general and oral health of children. The aim of the present study was to evaluate the effect of chronic malnutrition on the oral health of children…
- Trial name
- NCT03529500
- Testing
- Caries detection - dmtf index, Saliva flow rate, Saliva Buffering Capacity
- Where
- Brazil
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Dental Caries
Medical Management of Caries in the Primary Dentition Using Silver Nitrate
This pilot trial compares conventional restorations with a new strategy based on the medical management of caries using silver nitrate and fluoride varnish with no restorations.
- Trial name
- NCT02604134
- Testing
- Prophylaxis, Fluoride varnish, Silver Nitrate
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Arwa Owais
Caries,Dental, Head and Neck Cancer
Prevention of Caries in Head and Neck Cancer Survivors Who Underwent Radiotherapy
One of the long-term side effects of head and neck radiotherapy (RT) is radiation-induced tooth decay. Hyposalivation, associated with radiation therapy, further increases caries susceptibility and caries progression, due to the…
- Conditions
- Caries,Dental, Head and Neck Cancer, Radiotherapy; Complications
- Trial name
- RADIOCARIES (NCT06308796)
- Testing
- Application of CaP dental mousse
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Milan
Dental Caries
Preventive and Therapeutic Proximal Sealants
It is of clinical importance to arrest the development of approximal caries at an early stage. The potential for initial caries to develop into manifest lesions has motivated studies on the use of sealants to arrest the…
- Trial name
- PTPS (NCT02338180)
- Testing
- proximal preventive sealants, proximal therapeutic sealant
- Where
- Chile
- Volunteers
- 390 people
- Sponsor
- Universidad de Valparaiso
Dental Caries in Children
Evaluation of Two Different Types of Zirconia Crowns Used in Carious Primary Anterior Teeth
Evaluation of two different types of zirconia crowns ( Kinder Krown , Nusmile crown) used in carious primary anterior teeth
- Trial name
- NCT05121584
- Testing
- Placement of an anterior crown restoration as a final restoration
- Where
- Egypt
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Arig Samir Abdelmonem Shawky
Dentin Hypersensitivity
Effect of Gluma and Bioactive Glass Desensitizers in Treatment of Dentin Hypersensitivity in Cervical Non-Carious Lesions
Type of study: (A Randomized Controlled Clinical Trial) Aim :The aim of this randomized controlled clinical trial is to evaluate the effect of Gluma, Bioactive Glass and combination of both, compared to Flouride Varnish on the…
- Trial name
- NCT07063433
- Testing
- Gluma Desensitizer, Bioactive glass, Fluoride varnish
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- British University In Egypt
Carious Teeth
Clinical Performance of One-shade Universal Dental Resin Composite as Posterior Restoration
This study is aimed to evaluate the clinical performance of new One-shade universal composite resin as posterior restoration using US Public Health Service "USPSH" criteria for color match, marginal adaptation, surface texture…
- Trial name
- NCT05500547
- Testing
- US Public Health Service "USPSH" criteria for assessment of success of resin composite restorations
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Minia University
Dental Caries
Delivery of Polyphenols in Gum as an Anti-Caries Agent
The short-term effects of chewing gum containing xylitol and/or blackberry extract on oral microbiota was studied. Fifty healthy adults participated in a randomized, placebo-controlled, cross-over design study.
- Trial name
- BBE (NCT05133557)
- Testing
- Chewing gum containing xylitol and blackberry extract (BBE)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Craig Miller
Dental Caries
EFFICACY OF MORUS ALBA FRUIT EXTRACTS AND CHLORHEXIDINE ON SALIVARY STREPTOCOCCUS MUTANS AND pH LEVELS
Dental caries is highly prevalent across the globe including Pakistan and is associated with tooth loss, malocclusion and temporomandibular joint problems and sometimes may cause life threatening infections.
- Trial name
- NCT05052775
- Testing
- Chlorhexidine Mouthwash, Morus Alba 20%, Morus Alba 30%
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Ziauddin University
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