Clinical trials: Carious Lesion
HIV, Dental Caries
An Educational Intervention Program to Improve the Oral Health of HIV-Positive Children in Kano, Nigeria.
The aim of this 2- arm randomized-control study is to determine the effect of an oral hygiene self care intervention on the oral health status and oral health-related quality of life (OHRQoL) of HIV-positive children (age: 8-16…
- Conditions
- HIV, Dental Caries, Quality of Life, Oral Disease
- Trial name
- NCT05540171
- Testing
- Oral health education and instructions/training for self-oral care
- Where
- Nigeria
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Aminu Kano Teaching Hospital
Dental Caries, Streptococcal Infections
Evaluation of Efficacy of Antibacterial Activity of Licorice, Clove, and Chlorohexidine Mouthwashes on Salivary Streptococcus Mutans in a Group of Egyptian Children.
A randomized controlled trial that compares the antibacterial effectiveness of three mouthwashes-licorice, clove, and chlorhexidine-in Egyptian children aged 7-12 years.
- Conditions
- Dental Caries, Streptococcal Infections, Mouthwashes
- Trial name
- NCT07828171
- Testing
- Mouth wash
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- British University In Egypt
Pain, Dental Caries
Comparison of Intraosseous Anesthesia and Inferior Alveolar Nerve Block for Primary Mandibular Molars
The aim of the present study is to compare computerized intra-osseous injection system to the conventional inferior alveolar nerve block in primary mandibular teeth.
- Trial name
- NCT07846098
- Testing
- Inferior Alveolar Nerve Block, intraosseous anaesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Dental Caries
Survival Rate and Cost-effectiveness of Conventional vs ART Restorations in a School Setting
This study will investigate the performance and cost-effectiveness of glass-ionomer restorations placed in school children in an outreach setting in rural areas in South Africa over a 2-year period, when placed using either ART…
- Trial name
- NCT05766696
- Testing
- Atraumatic Restorative Treatment (ART), Conventional Cavity Preparation
- Where
- South Africa
- Volunteers
- 200 people
- Sponsor
- DMG Dental Material Gesellschaft mbH
Dental Caries
Effectiveness of Fluoride Varnish in Prevention of Dental Caries in School Children
Despite the availability of free health dental service in Sri Lanka, the prevalence and severity of dental caries among 6year old school children stand at a very high level according to the results of national oral health survey…
- Trial name
- NCT02877888
- Testing
- fluoride varnish 22600ppm
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- University of Peradeniya
Dental Caries in Children
Comparison of a Chemically Activated Composite Resin Alkasite With Resin Composite in Atypical Caries Lesions of Deciduous Teeth
Atypical cavities, which involve more than two surfaces, one being buccal or lingual/palatal, are a challenge for restorative dentistry, since the risk of restorative failure is related to the number of surfaces involved.
- Trial name
- NCT04195022
- Testing
- Dental Restoration with Chemically activated Composite resin Alkasite, Dental Restoration with Bulk fill resin composite
- Where
- Brazil
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Faculty Sao Leopoldo Mandic Campinas
Dental Caries in Children
Evaluation of New Different Herbal Mouthwashes Against Caries Forming Bacteria, RCT
The goal of this randomized controlled trial is to compare three different types of mouthwash, Moringa, Star anis, and Indian Costus 90 children participated in this study divided into 3 groups according to the type of mouthwash…
- Trial name
- NCT05623605
- Testing
- Moringa mouthwash, star anise mouthwash, Indian costus mouth wash
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Nahda University
Dental Caries
Dental and Oral Finding in Israeli Children With Past Intrauterine Growth Retardation (IUGR)
oral status and early childhood caries (ecc) in israeli children with past IUGR
- Trial name
- NCT00867542
- Testing
- no intervention
- Where
- Israel
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Dental Caries
Clinical Evaluation of Zirconia Crowns and Anterior Strip Crowns
The hypothesis to be investigated is that no difference will be found upon comparing resin composite strip crowns and NuSmile zirconia crowns (NuSmile ZR) esthetic primary anterior in restoring anterior primary teeth.
- Trial name
- NCT03184012
- Testing
- NuSmile Zirconia crowns by NuSmile company, Composite resin strip crowns by 3M company
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Caries, Dental
Alternative Treatment of Deep Carious Lesions Based on Biological Evidences
The purpose of this study is to evaluate the success rate of alternative treatment of deep carious lesions in asymptomatic primary teeth with no clinical nor radiographic signs of pulpal inflammation.
- Trial name
- NCT00973089
- Testing
- Incomplete caries removal in primary teeth
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Aerosol Disease, Caries,Dental
Quantitative Evaluation of Aerosols Produced in the Dental Office
Background: Maintaining biosafety in dental practice requires an efficient elimination of aerosols produced during dental treatment.
- Trial name
- NCT05988359
- Testing
- Caries treatment with a dental turbine, Caries treatment with Er:YAG laser
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Dental Caries in Children
Prevalence of Dental Caries Among a Group of Egyptian Children Using CAST Index
The aim of this study is to assess the prevalence of dental caries using CAST index among a group of Egyptian children in primary dentition stage.
- Trial name
- NCT03573180
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Cairo University
Prevention of Dental Caries
Comparative Analysis of Interventions for Prevention of Dental Caries in School Children
A study aims to assess the most effective preventive interventions to address the widespread issue of dental caries, affecting an estimated 2 billion people in permanent teeth and over 500 million children in primary teeth…
- Trial name
- NCT06602765
- Testing
- Tooth brushing, tooth paste containing 1450ppm fluoride
- Where
- Pakistan
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Bahria University
Caries, Dental
Effectiveness of Er:YAG Pulse Therapy for Achieving Pre-emptive Dental Analgesia in Children
The aim of this study is to determine the effectiveness of Er:YAG pulse therapy for achieving pulpal analgesia in pediatric patients and to quantify the duration and extent of any effects assessed.
- Trial name
- NCT03412721
- Testing
- Laser analgesic procedure
- Where
- Bulgaria
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Plovdiv Medical University
Gingival Recession
Two Surgical Approaches for Root Coverage of Teeth Presenting Gingival Recession and Non-carious Cervical Lesion
The aim of the present study is to compare the use of the xenogeneic graft (MC) plus coronary advanced flap (CAF) and the coronary advanced flap alone, both associated with the partial restoration of composite resin in the…
- Trial name
- NCT03341598
- Testing
- CAF, R, MC
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Dental Caries in Children
Cost-effectiveness of Topical Fluoride in Preventing Deciduous Dental Caries in Preschool Children
Fluoride foam and fluoride varnish are effectiveness in prevention deciduous dental caries. However, the relative clinical efficacy and cost-effectiveness of these two interventions are uncertain.
- Trial name
- NCT05025163
- Testing
- 1.23% fluoride foam application, 2.26% fluoride varnish application
- Volunteers
- 1,083 people
- Sponsor
- National Center for Chronic and Noncommunicable Disease Control and Prevention, China CDC
Single Posterior Crowns, Badly Decayed Teeth, Teeth Restored With Large Filling Restorations or Endodontically Treated Teeth
One Year Clinical Evaluation of Milled BioHPP Polyetheretherketone (PEEK)-Based Versus Metal Ceramic Single Crowns
Although the metal-ceramic system is still widely used to fabricate crowns and fixed partial dentures and is considered as the standard treatment in dentistry, aesthetic concerns have stimulated the development of new dental…
- Conditions
- Single Posterior Crowns, Badly Decayed Teeth, Teeth Restored With Large Filling Restorations or Endodontically Treated Teeth, Malformed Teeth, Malposed Teeth (Tilted, Over-erupted, Rotated, Etc.) or Spacing Between Posterior Teeth
- Trial name
- NCT03685513
- Testing
- BioHPP PEEK-based single posterior crowns, Metal ceramic single posterior crowns
- Volunteers
- 46 people
- Sponsor
- Cairo University
Dental Caries, Insufficient Dental Filling
A Clinical Trial to Compare the Safety and Performance of Two Different Curing Modes in the Direct Filling Therapy in Deciduous Teeth
The overall aim of this clinical investigation is to assess the clinical performance and safety of composite restorations cured with fast curing mode (5 seconds with 2000 mW/cm²) in primary molars.
- Trial name
- NCT07212660
- Testing
- Fast curing mode, Conventional curing mode
- Where
- 2 sites in Switzerland
- Volunteers
- 70 people
- Sponsor
- Ivoclar Vivadent AG
Dental Caries
Safety Evaluation of Advantage Anti-Caries Varnish
The purpose of the study is to confirm the safety of Advantage Anti-Caries Varnish.
- Trial name
- NCT02645617
- Testing
- Varnish
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Advantage Dental Services, LLC
Decayed Teeth
Vital and Non-vital Posterior Teeth Restored With Onlays and Single Crowns Using Three Different Restorative Materials.
The objective of this study is to assess the survival rate and the biological and technical outcomes of onlays and single crowns made out of different restorative materials on vital and non-vital teeth.
- Trial name
- NCT07259265
- Testing
- Crown preparation, Onlay preparation
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Dr. med. dent. Malin Strasding
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