Clinical trials: Carious Lesion
Dental Caries
Safety Evaluation of Advantage Anti-Caries Varnish
The purpose of the study is to confirm the safety of Advantage Anti-Caries Varnish.
- Trial name
- NCT02645617
- Testing
- Varnish
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Advantage Dental Services, LLC
Dental Caries
Caries Transmission Prevention in Alaska Native Infants
The purpose of this study is to conduct a community based, randomized control trial to determine if the use of chlorhexidine mouth rinse and xylitol-sweetened chewing gum will reduce the vertical transmission of caries between…
- Trial name
- NCT00067340
- Testing
- Chlorhexidine mouth rinse, Xylitol chewing gum
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Washington
Dental Caries
Efficacy of Two Protocols for Applying Fluorine Varnish to Deciduous Teeth
Evidence that the data flow analysis tests, there are still no studies that show the clarity of the protocols of its application, including the interval and execution factors of applications, concentration of fluoridation and…
- Trial name
- CEPECO3 (NCT03827889)
- Testing
- WMP of fluoride varnish, TWLP of fluoride varnish, DHP (educational intervention)
- Where
- Brazil
- Volunteers
- 168 people
- Sponsor
- Universidade Ibirapuera
Dental Caries
Evaluation of Antimicrobial Photodynamic Therapy as an Adjunct Treatment of Deep Carious Lesions in Children
This project aims to evaluate the effect of antimicrobial photodynamic therapy (aPDT) in deep carious lesions. This study was approved by the Research Ethics Committee and was conducted on 53 patients between 3 and 12 years.
- Trial name
- NCT02908789
- Testing
- Antimicrobial photodynamic therapy (aPDT), Without Antimicrobial phothodynamic therapy
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Dental Caries
The Effectiveness of iTero Element 5D NIRI System in Early Proximal Caries Detection in Permanent Teeth
As a new emerging technology for the diagnosis of dental caries, near-infrared imaging requires further research and validation to determine its effectiveness.
- Trial name
- NCT06276959
- Testing
- intraoral scanning, clinical oral examination, cone-beam computed tomography
- Where
- China
- Volunteers
- 120 people
- Sponsor
- West China College of Stomatology
Dental Caries in Children
Prevalence of Dental Caries Among a Group of Egyptian Children Using CAST Index
The aim of this study is to assess the prevalence of dental caries using CAST index among a group of Egyptian children in primary dentition stage.
- Trial name
- NCT03573180
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dentin Caries
Evaluation of ART Restorations Using Two Different Bulk-Fill Restorative Materials in Primary Molars
The aim of this clinical study is to evaluate the success of two different bulk-fill restorative materials applied to teeth restored with atraumatic treatment at 3, 6, and 12-month follow-ups.
- Trial name
- NCT06771362
- Testing
- ART with Bulk-Fill composite, ART with Glass Ionomer
- Where
- Turkey (Türkiye)
- Volunteers
- 127 people
- Sponsor
- Çanakkale Onsekiz Mart University
Caries,Dental, Pain
Comparative Evaluation of SMART Hall Technique Vs. Conventional SS Crown in Primary Molars: a Randomized Clinical Trial
Dental caries, particularly in primary molars, significantly affects children's oral health and overall well-being. Traditional management with stainless steel crowns (SSCs) involves significant tooth reduction and advanced…
- Conditions
- Caries,Dental, Pain, Plaque, Dental, Gingival Bleeding
- Trial name
- RCT (NCT06453005)
- Testing
- SMART Hall Technique or procedure
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- C K S Teja Institute Of Dental Sciences & Research
Caries,Dental, Remineralization
Remineralization Efficacy of Gum Arabic Varnish.
The aim of this study is to evaluate the remineralizing capacity of Gum Arabic varnish and its implementation into clinical practice.
- Conditions
- Caries,Dental, Remineralization, White Spot Lesion
- Trial name
- NCT04422860
- Testing
- Gum Arabic varnish, Proflourid Varnish,VOCO, MI Varnish,GC Japan Inc.
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Antibacterial Effect of Nano Silver Fluoride vs Chlorhexidine on Occlusal Carious Molars Treated With Partial Caries Removal Technique
The teeth of the patients that meet inclusion criteria will be anesthetized, isolated with a rubber dam. Cavity opened using conventional high-speed rotary instruments.
- Trial name
- NCT03186261
- Testing
- Nano silver fluoride solution, Cavity Cleanser
- Where
- Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Cairo University
Root Caries
Silver Diamine Fluoride Treatment of Active Root Caries Lesions in Older Adults: A Case Series
The authors conducted a case series to determine the outcomes of treatment of root surface caries lesions when the teeth were treated topically with 38% silver diamine fluoride.
- Trial name
- NCT04370080
- Testing
- Silver Diamine Fluoride 38%
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Roseman University of Health Sciences
Dental Caries, Periodontitis
Breaking the Cycle: Real-Time Family Oral Microbial Transmission Patterns as Intervention Targets
This study aims to understand how oral bacteria that cause tooth decay and gum disease spread among family members and whether treating multiple family members can reduce the return of these bacteria after dental treatment.
- Conditions
- Dental Caries, Periodontitis, Oral Microbiome, Bacterial Transmission
- Trial name
- NCT07674888
- Testing
- Professional Dental Plaque Disruption
- Where
- Canada
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Decay, Dental
Evaluating the Efficiency of Newly Designed Prefabricated PMMA Crowns for Restoring Primary Teeth in Comparison to Stainless Steel and Zirconia Crowns
Evaluation of PMMA pediatric crowns
- Trial name
- NCT04479046
- Testing
- PMMA crowns
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Ain Shams University
Tooth Decay, Tooth Restoration
Clinical and Radiographic Evaluation of Two Matrix Systems for Restoration of Class II Cavities in Primary Molars
this study aims to evaluate and compare the clinical and radiographical efficacy, operator ease, satisfaction and patient comfort in restoring class II cavities in primary molars using Fender Mate system with T-band system.
- Trial name
- NCT06447324
- Testing
- Fender Mate matrix system, T-band matrix
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Aswan University
Dental Caries, Tooth Extraction
Treating Children With Extensive Dental Needs
The goal of this qualitative study, using Grounded Theory, is to gain deeper knowledge about dentists' experiences from treating in particular young children with an extensive treatment need (mainly due to caries).
- Conditions
- Dental Caries, Tooth Extraction, Conscious Sedation, Attitude
- Trial name
- NCT06863103
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Malmö University
Root Caries
Effectiveness on SDF Solution and PVP-I Combined NaF Varnish in Preventing Root Caries in Elders
The main objective of this study is to compare the effectiveness and cost-effectiveness of 4-monthly application of 10% povidone iodine solution followed by 5% sodium fluoride varnish with those of annual application of 38%…
- Trial name
- NCT03654820
- Testing
- PVP-I solution combined with NaF varnish, SDF solution
- Where
- China
- Volunteers
- 353 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Class V Dental Caries, Composite Resin and Self Adhesive Flowable Composite
One Year Clinical Performance of Self Adhesive Giomer Containing Flowable Composite in Restoring Class V Cavities
This clinical trial will be conducted to compare the clinical performance of self adhesive giomer containing flowable composite and putty nanohybrid resin composite in class V cavities over one year follow-up
- Trial name
- NCT04944485
- Testing
- (FIT SA F03, SHOFU, USA), (Neo Spectra™ ST, Dentsply, Sirona, USA)
- Volunteers
- 46 people
- Sponsor
- Cairo University
Cervical Caries
Nobio Antimicrobial Particles Effect in a Split Mouth Model
The study purpose is to evaluate the antimicrobial effect of Nobio particles incorporated within Novidia Dental Bonding and Flowable Composite versus standard of care within a split mouth model.The study population will include…
- Trial name
- NCT03501784
- Testing
- Nobio particles incorporated within Novidia Dental Bonding, Filtek bond and flow composite
- Where
- Israel
- Volunteers
- 35 people
- Sponsor
- Nobio Ltd.
Dental Caries Extending to Pulp, Pulp Disease, Dental
The Effect of Different Risk Factors on the Success Rate of VPT
This study aims to evaluate the effectiveness of various vital pulp therapy (VPT) methods, such as direct pulp capping, partial pulpotomy, and total pulpotomy, in maintaining pulp vitality following pulp exposure.
- Conditions
- Dental Caries Extending to Pulp, Pulp Disease, Dental, Irreversible Pulpitis, Reversible Pulpitis
- Trial name
- NCT06844448
- Testing
- with Biodentine, with MTA
- Where
- Hungary
- Volunteers
- 400 people
- Sponsor
- Semmelweis University
Dental Caries
Dental and Oral Finding in Israeli Children With Past Intrauterine Growth Retardation (IUGR)
oral status and early childhood caries (ecc) in israeli children with past IUGR
- Trial name
- NCT00867542
- Testing
- no intervention
- Where
- Israel
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
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