Clinical trials: Carious Lesion
Dentine Caries
Diamine Silver Fluoride and Potassium Iodide
Dental caries is an infectious disease mediated by a consortium of microbes in the oral cavity. The disease is characterized by demineralization of the tooth, if untreated, it leads to cavitation, discomfort, pain and eventual…
- Trial name
- NCT02771704
- Testing
- Silver Diamine fluoride, Potassium iodide, Chlorhexidine
- Volunteers
- 5 people
- Sponsor
- Kuwait University
Dental Caries Class II, Dental Caries in Children
Arrest of Proximal Caries Using Orthodontic Bands and Glass Ionomer Cement
The purpose of this study is to evaluate the efficacy of using orthodontic bands with glass ionomer cement to arrest or reverse interproximal lesions as a preventive treatment compared to monitoring and oral hygiene.
- Conditions
- Dental Caries Class II, Dental Caries in Children, Dental Caries on Smooth Surface Limited to Enamel
- Trial name
- NCT04538963
- Testing
- Orthodontic Band affixed with Glass Ionomer Cement
- Where
- 2 sites in United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Dental Adhesives/Restorations Performance
NCCL Direct Composite Restoration Performance With Self-Etch and Multimode Adhesives
The purpose is to evaluate/compare clinical effectiveness of dual cure (DC) all-in-one Self-Etch (Futurabond® DC (FBDC)) adhesive and multimode/universal (Futurabond® U (FU) and Adhese® Universal (AU)) adhesives, with or without…
- Trial name
- SEMMAP (NCT02698371)
- Testing
- G1-Control: Futurabond®DC-SE (FBDC_SE), G2-Control: Futurabond®DC_SE_EE, G3: Futurabond® U - ER (FBU_ER)
- Where
- Portugal
- Volunteers
- 38 people
- Sponsor
- University Fernando Pessoa
Dental Caries
Evaluation of CAMBRA Versus ICCMS Caries Risk Assessment Models Acquisition On Treatment Plan
randomized clinical study to evaluate 'caries management by risk assessment' Versus 'international caries classification and management system' Caries Risk Assessment Models Acquisition On Treatment Plan In Young Adult Population…
- Trial name
- NCT03668093
- Testing
- ICCM, CAMBRA
- Where
- Egypt
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Cairo University
Caries,Dental, Sensitivity, Tooth
Post-operative Sensitivity in Resin Composites
This triple-blind, randomized clinical trial was conducted at the department of Operative dentistry. A total of 60 participants were recruited and were randomly distributed into two groups A and B.
- Trial name
- NCT06242184
- Testing
- Group A(Nano-fortified Adhesive), Group B(Adhesive without nanoparticles)
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Dental Caries
Fluoride Varnish Randomized Clinical Trial
The purpose of this study is to compare the efficacy of fluoride varnish (FV) applied once or twice a year with counseling to counseling alone in preventing early childhood caries (ECC) (tooth decay in children under the age of…
- Trial name
- NCT00066963
- Testing
- Fluoride Varnish
- Where
- United States
- Volunteers
- 376 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cervical Caries
Clinical Evaluation of Self-Adhesive Bulk-Fill Composite Versus Conventional Nano-hybrid Composite in Cervical Cavities
The aim of this randomized clinical trial is to compare the six months clinical performance of the self-adhesive bulk-fill composite with the conventional nano-hybrid composite in the cervical lesions of teeth in the esthetic…
- Trial name
- NCT06394440
- Testing
- Self-Adhesive Bulkfill Composite (Surefil One)
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Misr International University
Dental Caries
Chemomechanical Caries Removal Using Papain Gel
To evaluate the efficacy of a papain-based gel in caries removal.
- Trial name
- CMCR09 (NCT01811420)
- Testing
- Chemomechanical Caries Removal, Conventional method
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Dental Caries, Caries Arrested
CARIES ARREST USING SILVER DIAMINE FLUORIDE VERSUS FISSURE SEALANT IN OCCLUSAL DENTAL CARIOUS LESIONS
The goal of this randomized clinical trial is to evaluate if Silver Diamine Fluoride (SDF) is a more conservative and effective treatment in preventing the progression of mild occlusal caries compared to fissure sealant in…
- Conditions
- Dental Caries, Caries Arrested, Silver Diamine Fluoride, Fissure Sealant
- Trial name
- NCT06861725
- Testing
- Silver Diamine Fluoride (SDF), VOCO Fissurit
- Where
- Egypt
- Volunteers
- 76 people
- Sponsor
- Cairo University
Dental Caries
In Vivo Comparison of Salivary Fluoride Levels Following the Application of Different 5% NaF Varnishes
This study will be a cross-over single blinded clinical study to evaluate the in vitro fluoride release of three different brands of 5% NaF varnish.
- Trial name
- NCT01629290
- Testing
- Enamel Pro, Duraphat, Vanish
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Dental Caries
Clinical Performance of Bioactive Highly Filled Injectable Flowable Composite for Direct Posterior Occlusal Conservative Restorations Using FDI Criteria: Two Year Randomized Clinical Trial
The aim of this study is to evaluate Clinical Performance of bioactive highly filled injectable flowable composite for direct posterior occlusal conservative restorations using FDI Criteria
- Trial name
- NCT06790511
- Testing
- bioactive highly filled injectable flowable composite, highly filled injectable flowable composite
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
The Prevalence of White Spot Lesions During Orthodontic Treatment With Fixed Appliances
This study investigates how often cavities develop on the permanent teeth of patients with braces (orthodontic treatment). The hypothesis is that there is no difference in the number of cavities on the permanent teeth of patients…
- Trial name
- WSLs (NCT04186065)
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Hiroko Nagaoka
Dental Caries in Children, Tooth Diseases
Hall Technique or Modified Hall Technique of Deep Carious Lesions in Primary Molars
The purpose of this randomized clinical trial is to compare the clinical/radiographic success of Hall technique and modified Hall technique in the treatment of primary molars with deep dentine carious lesions in children…
- Conditions
- Dental Caries in Children, Tooth Diseases, Tooth Demineralization, Stomatognathic Diseases
- Trial name
- NCT05220865
- Testing
- Hall Technique, Modified Hall Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Dental Caries
Clinical Evaluation of Zirconia Crowns and Anterior Strip Crowns
The hypothesis to be investigated is that no difference will be found upon comparing resin composite strip crowns and NuSmile zirconia crowns (NuSmile ZR) esthetic primary anterior in restoring anterior primary teeth.
- Trial name
- NCT03184012
- Testing
- NuSmile Zirconia crowns by NuSmile company, Composite resin strip crowns by 3M company
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Dental Caries
Clinical Comparison of Restorative Materials
Composite resin materials are the first treatment choice in direct restorations due to their good mechanical properties, excellent esthetic properties, conservative preparation, and successful clinical performance.
- Trial name
- NCT06637605
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
Dental Caries in Children
Water From Bottles to Establish Strong Teeth
The waterBEST study is a proof-of-concept, randomized, double-masked, placebo controlled, parallel group study evaluating dental caries-preventive effects of fluoridated bottled water compared to non-fluoridated bottled water in…
- Trial name
- waterBEST (NCT04893681)
- Testing
- Fluoridated bottled drinking water, Non-fluoridated drinking water
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Dental Caries
Evaluation of Reliability of CarieScan PRO Compared With Digital Radiograph and ICDAS-II in Detection of Carious Lesions
The aim of this study is to evaluate the Clinical performance of alternating current impedance spectroscopy (CarieScan PRO) in comparison with digital radiograph and ICDAS-II in detection of occlusal carious lesions.
- Trial name
- NCT04438252
- Testing
- ICDAS II, CariScan Pro, Digital Radiograpgy
- Where
- Egypt
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Cairo University
Class II Dental Caries
Clinical Performance of Bulk-Fill Composite Using With Adhesives With or Without Chlorhexidine
This study aims to evaluate the clinical success of chlorhexidine-containing dentin bonding agent in primary molars with a 12-month follow-up.
- Trial name
- NCT06257108
- Testing
- Class II Cavity Restorations
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Uşak University
Sclerotic Dentine, Non Carious Cervical Lesion
Clinical Performance of Different Adhesive Strategies With a Universal System in Sclerosed Dentin in NCCL: A Double-blind Randomized Clinical Trial.
The aim of this randomized, prospective, parallel, double-blind clinical trial will be to evaluate the clinical performance of restorations performed in non-carious cervical lesions (NCCL) using a soft ph universal adhesive…
- Trial name
- NCT05211908
- Testing
- Composite resin restoration with Self Etch adhesive protocol and absence of sclerotic dentin, Composite resin restoration with Seletive enamel etch adhesive protocol and absence of sclerotic dentin, Composite resin restoration with Self Etch adhesive protocol and presence of sclerotic dentin
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Composite Post, Intracanal Reinfocement
Evaluation of Intracanal Reinforcement with Short Composite Post in Upper Primary Incisors with Severly Carious Teeth As in Early Childhood Caries Cases Using Randomized Clinical Trial
Severely damaged incisors may lead to difficulty in speech, decreased masticatory efficiency, abnormal tongue habits, subsequent malocclusions, and psychological and self-esteem problems.
- Trial name
- NCT06740643
- Testing
- intracanal reinforcement using short composite post, no intracanal reinforcement
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Cairo University
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