Clinical trials: Carious Lesion
Dental Caries
Clinical Trial of the Effect of Different Categories of Adhesive System
This study aims to evaluate the clinical effectiveness of contemporary resin-based adhesive systems by retention rate of resin restorations placed in non carious cervical lesions with four different adhesive strategies: 3 and 2…
- Trial name
- NCT02751970
- Testing
- Dental restoration, 3 step ER, 2 step ER
- Where
- Chile
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Universidad de Valparaiso
Dental Caries (Diagnosis), Dental Plaque (Diagnosis)
Intra Oral Scan and CBCT Aided Diagnosis of Dental Plaque and Caries
In this prospective controlled trial, patients will be enrolled at the University Hospital Ghent. Inclusion criteria are: age between 18 and 70 years old, presence of 20 or more teeth, and have a minimum one carious tooth…
- Trial name
- NCT06945354
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- University Ghent
Ballet Dancers, Caries, Cervical
PICN Versus Bioactive Composite for Cervical Restorations in Ballet Dancers
Background and Objectives: Professional ballet dancers endure high occlusal loads, increasing cervical defect prevalence. Conventional composites fail frequently under such conditions.
- Trial name
- NCT07598305
- Testing
- Polymer-infiltrated ceramic network (PICN) - carious, Polymer-infiltrated ceramic network (PICN) - abfraction, Self-curing bioactive bulk-fill composite - carious
- Where
- Russia
- Volunteers
- 20 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Oral Health in Children With Inflammatory Bowel Disease
Oral Health in Children With Inflammatory Bowel Disease
In adults with inflammatory bowel disease (IBD), a higher prevalence of dental caries and periodontal disease has been reported compared with healthy control subjects, but similar data on children are missing in the literature.We…
- Trial name
- NCT05538923
- Testing
- No intervention was given to the patients
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Marmara University
Posterior Ceramic Onlays, Badly Decayed Teeth Need to be Restored , Teeth Restored With Large Filling Restorations
Functional Evaluation of Ceramic Onlay Restorations With Different Preparation Designs
Tooth preparation designs for posterior ceramic restorations have been based on traditional cast metal restoration designs, but with more occlusal tooth reduction and with a slightly increased taper.
- Trial name
- NCT04274959
- Testing
- ceramic onlay with shoulder preparation design., ,ceramic onlay with butt joint preparation design
- Volunteers
- 39 people
- Sponsor
- Cairo University
Cervical Lesion, Dental
Evaluating Universal Adhesives in Cervical Lesions
The aim of this randomized controlled clinical trial is to evaluate the 12-month clinical performance of restorations placed in NCCLs using universal adhesives with different compositions according to FDI criteria.
- Trial name
- NCT07459374
- Testing
- G2 Bond Universal, GC Europe N.V., Leuven, Belgium, Scotchbond Universal Plus, 3M ESPE, St. Paul, MN, USA, Tokuyama Universal Bond II, Tokuyama Dental, Tokyo, Japan
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Bacterial Infections, Dental Caries
Hydrogen Peroxide Fumigation in Dental Office Environment
The study's null hypothesis posits no significant difference in bacterial levels in the dental office environment before and after implementing hydrogen peroxide (H₂O₂) fumigation.
- Conditions
- Bacterial Infections, Dental Caries, Aerosol Disease
- Trial name
- NCT06100848
- Testing
- Microbiological analysis after Caries treatment, Microbiological analysis after Caries treatment and fumigation
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Osteoporosis, Dental Caries
Salivary Cytokines, MMP-8 and Dental Caries in Osteoporosis Patients
This study examines saliva samples from patients with osteoporosis. The levels of cytokines and Matrix Metalloproteinase-8 (MMP-8) enzyme in saliva will be measured.
- Conditions
- Osteoporosis, Dental Caries, Biomarkers, Matrix Metalloproteinase 8
- Trial name
- NCT07709247
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
Head and Neck Cancer
Chlorhexidine Gel Therapy for Cariogenic Oral Microflora
The goal of this clinical research study is to find out if 1% chlorhexidine gluconate gel will decrease the amount of bacteria that causes tooth decay. Whether the gel is acceptable to patients will also be studied.
- Trial name
- NCT01036412
- Testing
- 1% Chlorhexidine Gluconate Gel, Surveys
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- M.D. Anderson Cancer Center
Dental Caries
Comparison of Clinical and Radiographic Outcomes of SMART Technique vs ART in Primary Molars
This study conducted on thirty children aged 3-6 years old of both genders, have bilateral carious lower first primary molars. Pre-operative periapical x- ray were taken for both sides.
- Trial name
- NCT05438381
- Testing
- Atraumatic Restorative Technique (ART), SMART Technique
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Dental Caries
Comparison of the Effect of Fluoride Remineralizer Gel and Foam
Compare the remineralizing effect of acidulated fluoride gel Flugel (1.23% FFA, DFL) and acidulated Fluoride Foam Flúor Care (1.23% FFA, FGM) in maxillary anterior permanent teeth of 58 children aged 7 to 12 years of age.
- Trial name
- NCT02490592
- Testing
- Fluoride Foam, Fluoride gel
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University Center of João Pessoa
Decay, Dental
General Dentists' Knowledge, Attitudes and Clinical Usage of SDF
This study will look at how dentists in the UK are using Silver Diamine Fluoride (SDF) in their everyday practice. SDF is a liquid treatment that helps stop tooth decay.
- Trial name
- GDPKAUSDF (NCT07405437)
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Chronic Kidney Diseases, Caries,Dental
Assessment of The Oral Health Status of Children With Chronic Kidney Disease
The aim of this study is to compare the oral health findings, salivary parameters and disease-related quality of life of children with different stages of Chronic Kidney Disease(CKD), those undergoing dialysis and…
- Conditions
- Chronic Kidney Diseases, Caries,Dental, Quality of Life, Saliva Altered
- Trial name
- NCT06578832
- Testing
- physical and chemical methods, biochemical methods, biochemical tests
- Where
- Turkey (Türkiye)
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Marmara University
Dental Caries, Dental Fillings
SEM Evaluation of the Quantity of microRepair® on Resin Composite Surfaces: an in Vivo Randomized Clinical Trial.
The aim of this study is to evaluate the quantity of Biorepair Total Protection toothpaste on composite surfaces inside oral cavity.
- Trial name
- NCT04808557
- Testing
- Biorepair Total Protection, Sensodyne Repair & Protect
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Dental Caries
Clinical Performance of Posterior Glass Ionomer Restorations in Adolescents (KETAC)
The purpose of this study is to determine whether two tooth-colored glass ionomer materials are effective for load-bearing dental fillings.
- Trial name
- NCT02705729
- Testing
- Ketac Universal, Ketac Molar Quick
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Dental Caries in Children, Pediatric Patients
Relationship Between Tooth Decay and Trabecular Bone
Chewing, a movement that matures with experiences, has effects on the growth and development of the stomatognathic system. Tooth decay, which is known to have effects on chewing, can affect the jaw bone due to its indirect effect…
- Conditions
- Dental Caries in Children, Pediatric Patients, Radiology
- Trial name
- NCT04608526
- Testing
- Fractal analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Dental Caries, Oral Cavity Cancer
Impact of Compliance With Fluoride Use on Caries Incidence After Cancer Therapy
Approximately 40 people will participate in this study. This study will compare two different methods of fluoride application. Both methods are currently used in dental practice and both have been shown to be effective.
- Conditions
- Dental Caries, Oral Cavity Cancer, Oral Complications of Chemotherapy and Head/Neck Radiation
- Trial name
- NCT03267914
- Testing
- Tray, Brush
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- A.T. Still University of Health Sciences
Dental Caries
Evaluation of Mineral Trioxide Aggregates and Grape Seeds Extract Effect on Pulpotomy
Pediatric dentistry has always debated the benefits of vital pulp therapy. AIM: The current study was done to differentiate the histo-pathological findings of MTA versus grape seed extract in primary teeth undergoing pulpotomy as…
- Trial name
- NCT06694064
- Testing
- Pulpotomy, extraction for histologic examination
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Dental Caries
Ethanolic Extract of Aloe Vera Versus Chlorohexidine as Cavity Disinfectant.
This Randomized Clinical Trial will be conducted to compare the efficacy of ethanolic extract of Aloe vera versus chlorhexidine cavity disinfectant in reducing total bacterial count of Streptococcus mutans (SM) and Lactobacilli…
- Trial name
- NCT04446364
- Testing
- Ethanolic extract of Aloe vera gel cavity disinfectant, Chlorohexadine
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Effect of CPP-ACP Paste on Dental Caries in Primary Teeth
The purpose of this study is to determine if adding daily application of CPP-ACP containing paste for one year is superior to regular fluoride tooth brushing in preventing dental caries in high caries risk Thai preschool children.
- Trial name
- NCT01604109
- Testing
- 10 % w/v CPP-ACP paste, the paste without CPP-ACP
- Where
- Thailand
- Volunteers
- 296 people, healthy volunteers welcome
- Sponsor
- Thammasat University
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