Clinical trials: Carious Lesion
Dental Caries
Evaluation of a Low Fluoride Dentifrice for Caries Control
The aim of this randomized clinical trial is to evaluate the effect of pH and fluoride concentration in liquid dentifrices in the control of dental caries in early childhood, in non-fluoridated area.
- Trial name
- NCT01623362
- Testing
- Low-fluoride acidic dentifrice, conventional dentifrice, neutral pH and low-fluoride dentifrice
- Where
- Brazil
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Federal University of Paraíba
Dental Caries, Prevention
Sealant Application by Interns After Tele-demonstration
Abstract Background: Dental caries remains a major public health issue worldwide, particularly among children. Pit and fissure sealants represent a high-quality, evidence-based preventive measure.
- Conditions
- Dental Caries, Prevention, Education
- Trial name
- TESS (NCT07232797)
- Testing
- tele-demonstration, traditional demonstration group
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Decayed Teeth
Laser Activation in Reducing Pain During and After Root Canal Treatment for Painful Lower Molar Teeth.
Effectiveness of lasers in reducing pain during and after root canal treatment for mandibular molar teeth affected with acute irreversible pulpitis.
- Trial name
- NCT04735120
- Testing
- iLASE DIODE LASERS
- Where
- India
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- CSI College of Dental Sciences and Research, Madurai
Dental Caries
Personalized Caries Management Versus Standard of Care for Preventing Incidence of Caries in Young Egyptian Adults
Basic standard of care emphasis only tooth brushing and flossing without addressing individual pathological factors. For this reason, randomized controlled clinical trials on personalized caries management are needed to be able…
- Trial name
- NCT03731780
- Testing
- Personalized Treatment, Chlorhexidine and Remineralization, Control
- Where
- Egypt
- Volunteers
- 81 people
- Sponsor
- Cairo University
Hypersensitivity Dentin, Tooth Hypersensitivity
Effectiveness of Bioactiveglass Air Abrasion Versus Fluoride Varnish in Management of Dentin Hypersensitivity
Will the use of Bioactive glass with air abrasion technology (Sylc) compared to Fluoride Varnish (Biflourid 10) affects the degree of pain in patients complaining from hypersensitivity due to non-carious lesions?
- Trial name
- NCT03285360
- Testing
- Sylc, fluoride varnish (Bifluorid 10)
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Oral Alkali Production and Caries Prevention in Children (Longitudinal)
The fact that dental caries remains a major public health problem mandates that oral-health researchers explore new strategies for assessment of caries risk, as well as for caries prevention and management.
- Trial name
- NCT02398695
- Testing
- Oral Samples
- Where
- United States
- Volunteers
- 232 people
- Sponsor
- University of Florida
Non-carious Cervical Lesion
Clinical Evaluation of Composite Restorations Using Two-steps Universal Adhesive in Non-carious Cervical Lesion (NCCL)
The goal of this clinical study is to compare the clinical performance of a new 2-steps universal adhesive in patients with non-carious cervical lesions.
- Trial name
- NCCL (NCT05573243)
- Testing
- bonding strategies
- Where
- Thailand
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Dental Caries in Children
Cost Effectiveness of Sodium Fluoride Varnish in Prevention of Dental Caries in School Children
Fluoride varnish application is universally accepted as a dental caries prevention method. This study was aimed in assessment of clinical outcome and cost effectiveness in using that method in Sri Lankan school children
- Trial name
- NCT03571815
- Testing
- 5% sodium fluoride varnish, WATER ON TEETH
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- University of Peradeniya
Carious Teeth
Outcome of Full Pulpotomy Using Calcium Silicate Based Materials
Permanent teeth with carious pulp exposure and indicated for full pulpotomy will be treated using three different materials using aseptic technique and will be subsequently followed up clinically and radiographically at 6 months…
- Trial name
- pulpotomy (NCT04345263)
- Testing
- MTA pulpotomy
- Where
- 2 sites in Jordan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Dental Caries
Population-centered Risk- and Evidence-based Dental Inter-professional Care Team
The main goal of the payment and delivery system reform is to reduce disparities in oral health and dental care access of low-income mothers and children living in rural Oregon counties.
- Trial name
- PREDICT (NCT02312921)
- Testing
- PREDICT
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Advantage Dental Services, LLC
Dental Caries, Caries; Dentin
The Preformed Metal Crowns Placed Using the Hall Technique Versus the Conventional Restoration
The aim of this study is to compare the survival rate of the conventional restorations with the Hall Technique in carious primary molars.
- Trial name
- NCT04818658
- Testing
- Assessment of the stainless steel crown using the Hall Technique and Compomer Restoration on primary molars
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Toothbrushing, Dental Plaque
BEhavioral EConomics for Oral Health iNnovation Trial
This Phase II stratified randomized prevention trial will assess the efficacy of a behavioral economic theory-based financial incentive drawing program versus a control regimen to promote early childhood caries (ECC) preventive…
- Conditions
- Toothbrushing, Dental Plaque, Parent-Child Relations, Oral Hygiene
- Trial name
- BEECON (NCT03576326)
- Testing
- Drawing Incentive
- Where
- United States
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cervical Caries
Clinical Evaluation of Self-Adhesive Bulk-Fill Composite Versus Conventional Nano-hybrid Composite in Cervical Cavities
The aim of this randomized clinical trial is to compare the six months clinical performance of the self-adhesive bulk-fill composite with the conventional nano-hybrid composite in the cervical lesions of teeth in the esthetic…
- Trial name
- NCT06394440
- Testing
- Self-Adhesive Bulkfill Composite (Surefil One)
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Misr International University
Dental Caries
Stopping Cavities Study: Diammine Silver Fluoride
This study is being conducted to test whether the use of diammine silver fluoride (also called silver diamine fluoride) hardens the cavity sufficiently so that it arrests.
- Trial name
- NCT02536040
- Testing
- 38% diammine silver fluoride, Water
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Advantage Dental Services, LLC
Dental Caries
Miswak Versus Standard Measures to Prevent the Incidence of Caries Young Egyptian Adults: A Randomized Controlled Clinical Trial
Objectives: Aim of the study The objective is to conduct an RCT to evaluate the effectiveness of miswak in comparison with standard caries preventive measures for the prevention of new carious lesions in high caries risk…
- Trial name
- NCT03732040
- Testing
- miswak stick, Miswak plus tooth brushing and tooth paste, Standard preventive measures (tooth brushing , interdental cleaning and mouth rinse use containing CHX and Fluoride)
- Where
- Egypt
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Predicting Caries Risk in Underserved Toddlers in Primary Healthcare Settings
The study aims to develop a questionnaire that can be used to help uncover a child's risk of developing dental caries (also known as tooth decay or a cavity).
- Trial name
- NCT01707797
- Where
- 3 sites in United States
- Volunteers
- 1,326 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Dental Caries
Giomer vs Glass Ionomer Cement for ART Occlusoproximal Restorations: a Randomized Clinical Trial
Although the Atraumatic Restorative Treatment (ART) is well settled in the literature regarding occlusal-proximal cavities, the longevity of these restorations is still lower when compared to occlusal ones.
- Trial name
- NCT02962713
- Testing
- ART with Equia, ART with Giomer Beautifil-Bulk Restorative
- Where
- Brazil
- Volunteers
- 182 people
- Sponsor
- University of Sao Paulo
Demineralization, Tooth, Caries,Dental
Prospective Randomized Controlled Trial for Prevention of Demineralization During Fixed Orthodontic Treatment
Treatment with fixed orthodontic appliances is often associated with pain, which poses great challenges in the efficient brushing of the teeth thus making the teeth more vulnerable to plaque formation.
- Conditions
- Demineralization, Tooth, Caries,Dental, White Spot Lesion
- Trial name
- NCT04342858
- Testing
- Fluoride Varnish, Fluoride Varnish with tricalcium phosphate, Oral health education
- Where
- Hong Kong
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Dental Caries, Pulpotomy
Comparison of Clinical Success of Stainless Steel Crowns and Zirconia Crowns in Primary Molars
Evaluation and understanding of clinical success, parental satisfaction and effects on periodontal tissues are the main expected benefits of prefabricated zirconia crowns and prefabricated stainless steel crowns.
- Trial name
- NCT06685640
- Testing
- prefabricated stainless steel crowns, prefabricated zirconia crowns
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Caries, Dental, Health Behavior
Interactive Parent-Targeted Text Messaging in Pediatric Clinics to Reduce Caries Among Urban Children
This is a randomized clinical trial to test the efficacy of a parent-targeted text message-based intervention program on caries incidence and oral health behaviors (child and parent).
- Trial name
- iSmile (NCT03294590)
- Testing
- OHT Parent targeted text messages, CWT Parent targeted text messages
- Where
- United States
- Volunteers
- 754 people, healthy volunteers welcome
- Sponsor
- Boston University
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