Clinical trials: Carotenoid
Carotenoid Status, Gut Microbiome
Probiotics for Enhanced Tissue Carotenoid Status in Premenopausal Women
Carotenoids are yellow-orange fat soluble plant pigments primarily obtained from the diet that serve as an accurate biomarker for fruit and vegetable intake.
- Conditions
- Carotenoid Status, Gut Microbiome, Skin Health
- Trial name
- ProCar (NCT04511052)
- Testing
- Probiotic, Carotenoid supplement
- Where
- Canada
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- McGill University
Retinopathy of Prematurity
Skin and Serum Carotenoids in Preterm Infants Fed on a Formula Supplemented With Carotenoids
The primary objectives of this study are to compare the serum and skin concentrations of beta-carotene, lutein, and lycopene in preterm infants fed preterm formulas with mixed carotenoids to serum concentrations in preterm…
- Trial name
- NCT00872664
- Testing
- carotenoids
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Utah
Eating Behavior
Healthy Online Parental Education Project to Increase Fruit and Vegetable Intake and Active Playtime Among Toddlers
The research proposal will be an 8-week randomized control trial (RCT) to examine the efficacy of an eHealth intervention, namely Healthy Parental Online Education (HOPE), on fruit and vegetable intake and active playtime among…
- Trial name
- HOPE (NCT05085041)
- Testing
- Multi-Component eHealth Intervention, namely Healthy Online Parental Education (HOPE)
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Vitamin A Deficiency
Vitamin A Absorption From Cassava in Women
The purpose of this study is to determine the vitamin A equivalents in high-carotenoid varieties of cassava.
- Trial name
- FL-80 (NCT01381276)
- Testing
- Beta-Carotene bio-fortified cassava porridge without oil, Beta-Carotene bio-fortified cassava porridge with oil, White cassava porridge with retinyl palmitate reference dose
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Vitamin A Deficiency
Vitamin A Bioavailability in Lactating Women With Marginal Vitamin A Status
The study will assess the relative bioavailability and bioefficacy of cryptoxanthin (CX) and beta-carotene (BC) from food sources for increasing breast milk carotenoid and retinol concentrations in lactating Bangladeshi women.
- Trial name
- NCT01420406
- Testing
- 0 mg retinol activity equivalents, 12 mg of BC, 6 mg of CX
- Where
- Bangladesh
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Will Consuming Eggs With a Mixed Vegetable Salad Increase Carotenoid Absorption
Effects of Egg Consumption on Carotenoid Absorption From Co-consumed, Non-Egg Food
The 2010 Dietary Guidelines for Americans emphasizes consumption of 4.5 cups of fruits and vegetables daily but average intake of US adults is only 2.6 cups.
- Trial name
- NCT01951313
- Testing
- Egg consumption
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Purdue University
Retinal Ageing
Carotenoid Supplementation and Normal Ocular Health
Normal ageing affects vision as a result of preretinal and retinal changes. Photoreceptors, the light sensitive cells in the retina, degenerate and the rods (responsible for night vision) are most susceptible to damage with…
- Trial name
- NCT02147171
- Testing
- VisionAce
- Where
- United Kingdom
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Manchester
PreTerm Birth
The Effect of Zinc, β-carotene, and Vitamin D3 in Preterm Delivery Through Placental MyD88, TRIF, NFkB, and IL-1β
This study is a controlled trial which compares the effect of zinc, beta-carotene, and Vitamin D3 supplementation in pregnant women which has preterm birth.
- Trial name
- NCT03005496
- Testing
- Zinc, Nifedipine, Beta Carotene
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Thigh Cellulite
Pilot Study of Naringenin Beta Carotene Cream for Local Fat Reduction (SCULPT)
this study tests the hypothesis that naringenin, beta carotene and menthol cream when applied to one thigh and a placebo cream to the other twice a day will result in greater loss of girth, smoother appearance of the skin and a…
- Trial name
- SCULPT (NCT07862920)
- Testing
- Thigh Reduction Cream
- Volunteers
- 10 people
- Sponsor
- Frank Greenway
Focus of Study: Carotenoid Absorption
Comparison of Carotenoid Bioavailability From Fresh Papaya, Tomato and Carrot
The goal of this study is to determine if papaya fruits are an exceptionally good food source for carotenoids in humans, particularly when compared more common carotenoid sources like carrots and tomatoes.
- Trial name
- NCT01748916
- Testing
- Papaya, Carrot, Tomato
- Where
- 2 sites in United States, Costa Rica
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Bioavailability Heathy Volunteers, Bioavailability and AUC
Bioavailability of Phlorotannins and Carotenoids Following the Intake of Crackers Fortified With Seaweed
The study aims to evaluate the bioavailability of phlorotannins and carotenoids from the seaweed Himanthalia elongata in healthy individuals after the consumption of a cracker fortified with this plant species.
- Trial name
- BIO-ALGA (NCT07508735)
- Testing
- Seaweed cracker, Control cracker
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National Research Council, Spain
Health Behavior
Evaluation of Changes in Skin Carotenoid Scores in Medical Students Following a Dietary Supplement-based Intervention
Skin Carotenoid Scores (SCS) are a biomarker of overall antioxidant status. This study extends an earlier study in which an increase in skin carotenoid scores (SCS) was observed in subjects who increased their intake of fruits…
- Trial name
- SCS2015 (NCT02464787)
- Testing
- LifePak Nano
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Gastrointestinal Tract Cancer
Serum Carotenoids and Risk of Gastrointestinal Tract Cancer: Meta-analysis of Ten Studies
Previous studies have suggested that serum carotenoids may be associated with risk of gastrointestinal tract cancer (GIT cancer), but the results were inconsistent.
- Trial name
- NCT03433092
- Testing
- serum carotenoids
- Where
- China
- Volunteers
- 40,641 people
- Sponsor
- Yong Zhou
Healthy, Nutrition Poor
Effects of Lutein on Visual Function
Randomized, double blind, placebo-controlled intervention trial on the ocular benefits and inflammatory markers improvements of taking FloraGLO Lutein for 9 months.
- Trial name
- NCT03113864
- Testing
- Lutein
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Kemin Foods LC
Vitamin A Status
Effect of Small Daily Doses of B-carotene on Breast Milk Retinol
The purpose of this pilot study is to determine whether breast milk retinol concentration increases in response to daily supplementation with small amounts of vitamin A (~600 ug RAE/d), as either a b-carotene or retinyl…
- Trial name
- NCT01803659
- Testing
- b-carotene, retinyl palmitate
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Menopause
Impact of Egg Consumption on Carotenoid and Vitamin D Bioavailability in Pre- and Post-menopausal Women
The 2010 Dietary Guidelines for Americans emphasizes consumption of 4.5 cups of fruits and vegetables daily but the average intake of US adults is only 2.6 cups.
- Trial name
- NCT02679794
- Testing
- Egg consumption, Control
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Purdue University
Photoaging
Oral Supplementation of Astaxanthin on Skin Photoaging, Hydration and Elasticity
This study is a double-blind placebo controlled study to assess whether oral astaxanthin can improve skin hydration, skin elasticity, improve skin pigmentation, and reduce facial redness.
- Trial name
- NCT05882084
- Testing
- Astaxanthin 6 mg daily
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Vitamin A Deficiency
Retinol Equivalence of Plant Carotenoids in Children
To determine vitamin A value of beta-carotene in oil capsule, spinach, and golden rice. The experiments will be conducted in children (ages 7-9) with/without adequate vitamin A nutrition.
- Trial name
- NCT00082420
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Absorption; Chemicals, Healthy Diet
Influence of Proteins on the Bioavailability of Carotenoids
A postprandial intervention study is conducted on healthy male subjects to evaluate whether the addition of proteins (why protein isolate, soy protein) can help to increase the bioavailability of carotenoids from a tomato/carrot…
- Conditions
- Absorption; Chemicals, Healthy Diet, Metabolism
- Trial name
- CAROPROT (NCT04078646)
- Testing
- Intervention with soy protein isolate, Intervention with whey protein, Intervention without protein addition
- Where
- Luxembourg
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Luxembourg Institute of Health
Healthy
Carotenoid Supplementation and Retinal Health in Healthy Adults
The purpose of this research is to evaluate the effect of oral dietary carotenoid supplements on various aspects of retinal health.
- Trial name
- NCT07314411
- Testing
- other
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Pacific University