Clinical trials: Carotenoid
Age-related Macular Degeneration
Consumption of Eggs Rich in Lutein and Omega-3 Fatty Acids on the Macular Pigment
This study is to determine the impact of the consumption of eggs rich in lutein/zeaxanthin from lucerne protein concentrate and DHA from microalgae on the plasma levels of these compounds but also on the macular pigment optical…
- Trial name
- ALGOVUE (NCT01480700)
- Testing
- Nutritional study
- Where
- France
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur de Lille
Cervical Cancer
Carotenoid Rich Diet in Treating Cervical Dysplasia
RATIONALE: A diet rich in carotenoids may be an effective treatment for cervical dysplasia. PURPOSE: Randomized phase II trial to study the effectiveness of a carotenoid rich diet in treating patients with cervical dysplasia.
- Trial name
- NCT00003094
- Testing
- preventative dietary intervention
- Where
- United States
- Sponsor
- University of California, San Diego
Vision, Eye Health
Eye and Carotenoid Augmentation Research and Evaluation (EyeCARE)
The primary study outcomes are to investigate the effects of 4-month daily carotenoid complex supplementation on carotenoid status in the macula and skin and visual fatigue among adults 20-45 years of age.
- Trial name
- EyeCARE (NCT06848101)
- Testing
- Carotenoid Group
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Mild Cognitive Impairment
The Effects of a Carotenoid Intervention on Cognitive Function
Past research suggests that retinal lutein levels are related to cognitive function as measured via behavioral tests. The goal of the present study is to investigate the relationship between lutein and cognitive function in a…
- Trial name
- NCT02023645
- Testing
- active supplement
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Carotenoids
Sweet Corn and Carotenoids
This study will assess the effect of daily yellow and white sweet corn intake on serum lutein and zeaxanthin concentrations. Skin carotenoid levels using the Veggie Meter will be assessed, and gastrointestinal symptoms and…
- Trial name
- NCT06892444
- Testing
- Yellow Sweet Corn, White Sweet Corn
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Florida
Lifestyle Risk Reduction
Analysis of Correlation Between Skin Carotenoid Level and Basic Indicators of Health Status Related to Lifestyle in Vietnamese: An Observational Study
To clarify the relationship between vegetable intake and lifestyle-related disease in Vietnam, we measure skin carotenoid levels and basic indicators of health status related to lifestyle and analyze the correlation between them.
- Trial name
- NCT06271070
- Testing
- Non-intervention
- Where
- Vietnam
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- KAGOME CO., LTD.
Skin Carotenoids
Assessment of the Effects of a Daily Supplement 4Life Transfer Factor Vista Containing AREDS2 Formula on Skin Carotenoid Levels Using a Non-invasive Detection
The goal of the clinical study is to evaluate the impact of daily use of a dietary supplement TF Vista containing AREDS2 formula ingredients, astaxanthin (Haematococcus pluvialis) microalgae, bilberry (Vaccinium myrtillus) fruit…
- Trial name
- NCT07513597
- Testing
- Dietary Supplement
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- 4Life Research, LLC
Noise-Induced Hearing Loss
Micronutrients to Prevent Noise-induced Hearing Loss
Noise-induced hearing loss (NIHL) is a significant clinical, social, and economic issue. Studies in animals have allowed us to identify mechanisms contributing to NIHL, including direct mechanical trauma, free radicals formed in…
- Trial name
- NCT00808470
- Testing
- beta-carotene, vitamins C and E, magnesium
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Healthy Volunteer, Skin Condition
CaroRite™ for Skin Health and Signs of Ageing
The goal of this study is to investigate the efficacy of carotenoids administered orally on skin health, skin condition and visible signs of ageing in healthy females aged 40-55 years old.
- Conditions
- Healthy Volunteer, Skin Condition, Ageing Signs
- Trial name
- NCT06878001
- Testing
- Carotenoids
- Where
- Australia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- RDC Clinical Pty Ltd
Intrinsically Labeled Spirulina
Vitamin A Value of Spirulina Carotenoids in Humans
The goal of this protocol is to determine the vitamin A value (equivalence) of spirulina. The investigation will use intrinsically deuterium labeled spirulina and an isotope vitamin A reference dose, 13C10- retinyl acetate (13C10…
- Trial name
- NCT00680277
- Testing
- spirulina ß-carotene
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tufts University
Macular Degeneration
Randomized Trial of Beta-Carotene and Macular Degeneration
To determine whether 50 mg of beta-carotene taken every other day reduces the risk of developing age-related macular degeneration (AMD) among male U.S. physicians who were aged 40 to 84 in 1982.
- Trial name
- NCT00000152
- Testing
- Aspirin, Beta-Carotene
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Diet Habit, Cognitive Control
Correlational and Intervention Effects of Egg Consumption on Macular Carotenoids, Cognition, and Achievement During Childhood
The aim of this study is to examine the correlational and intervention effects of egg consumption on macular carotenoids, cognition, and achievement during childhood.
- Trial name
- SHELL (NCT03521349)
- Testing
- Whole Egg Intervention, Egg White Control
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Vitamin A Deficiency
Effect of Daily Consumption of Orange Maize on Breast Milk Retinol in Lactating Zambian Women
The purpose of the study is to determine whether daily consumption of beta-carotene biofortified maize will increase breast milk retinol concentration in lactating Zambian women.
- Trial name
- NCT01922713
- Testing
- white maize and a corn oil capsule, orange maize and a corn oil capsule, white maize and a vitamin A capsule
- Where
- Zambia
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Digestion Chambers, Stability and Metabolism of Carotenoids and Vitamin E
Lycopene and Beta-carotene Metabolism in the Digestive Tract of Healthy Men
Consumption of foods containing carotenoids, as well as vitamin E, have been associated with lower risk of developing a number of chronic diseases.
- Trial name
- CarotenoiDig (NCT03492593)
- Testing
- lycopene, beta-carotene, control
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Prostate Cancer
Molecular Effects of a Multi-carotenoids (MCS) New Agent on Prostate Cancer Chemoprevention
This is to prospectively investigate whether the chemopreventive agent, MCS, may favorably alter biomarker expression, whether serum carotenoids levels are associated with biomarkers levels, and whether the alterations of…
- Trial name
- NCT02426216
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Hyaline Membrane Disease, Necrotizing Enterocolitis of Newborn
The Effect of β-Carotene, Vitamin D3 and Zinc on Hyaline Membrane Disease and Feeding Intolerance in Premature Neonates
Hyaline membrane disease, now commonly called respiratory distress syndrome (RDS), and feeding intolerance, which can lead to necrotizing enterocolitis (NEC), are two key morbidities found in premature neonates which resulted in…
- Trial name
- NCT03366584
- Testing
- Beta carotene, Vitamin D3, Zinc
- Where
- Indonesia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Vitamin A Deficiency
Impact of Consumption of Orange-fleshed Sweet Potatoes on the Vitamin A Status of Bangladeshi Women of Reproductive Age
The primary purpose of this study is to determine whether daily consumption of orange-fleshed sweet potatoes increases the vitamin A status of Bangladeshi women of reproductive age.
- Trial name
- NCT00453648
- Testing
- White-fleshed sweet potatoes, Orange-fleshed sweet potatoes (boiled), Orange-fleshed sweet potatoes (fried)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Eye Health, Age-related Macular Degeneration
Impact of Regular Consumption of Grapes on Eye Health in Singapore Older Adults
Aging epidemics in Singapore are rapidly increasing and Age-related macular degeneration (AMD) prevalence is significantly associated with older age.
- Trial name
- NCT05064865
- Testing
- Freeze-dried table grape powder
- Where
- Singapore
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Healthy, Ileostomy
The STOVITA Study - Bioefficacy of Beta-Carotene in Oil and in a Mixed Diet in Ileostomy Patients
A controlled dietary intervention study will be carried out based on the stable isotope method the investigators have developed to quantify both the absorption of beta-carotene and its bioconversion to retinol in oil and in a…
- Trial name
- NCT00128804
- Testing
- absorption and conversion of beta-carotene in human gastrointestinal (GI) tract
- Where
- Netherlands
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Retinitis Pigmentosa
9-cis Beta-Carotene-Rich Extract of Dunaliella Alga in Retinitis Pigmentosa Patients
The goal of this clinical trial is to learn if a natural supplement called 9-cis beta-carotene (derived from the Dunaliella alga) can improve vision and retinal function in adults with Retinitis Pigmentosa.
- Trial name
- NCT07509229
- Testing
- 9-cis beta-Carotene-rich extract of Dunaliella alga
- Where
- Israel
- Volunteers
- 41 people
- Sponsor
- Sheba Medical Center