Clinical trials: Carotid Artery
Carotid Artery Injuries, Traumatic Injury
Use of 81 vs 325mg of ASA in Treatment of BCVI
Blunt cerebrovascular injury (BCVI), or injury to the carotid and vertebral arteries, occurs in 1-3% of blunt traumas, often as a result of injury to the head, neck, or chest.
- Conditions
- Carotid Artery Injuries, Traumatic Injury, Vertebral Artery Injury
- Trial name
- NCT06383650
- Testing
- Acetylsalicylic Acid
- Volunteers
- 40 people
- Sponsor
- London Health Sciences Centre
Carotid Artery Diseases, Peripheral Arterial Disease
Study to Image Inflammatory Activity of a Fluorescence Imaging Agent in Excised Human Artery Plaques
Active inflammation plays a key role in causing Coronary Artery Disease (CAD) and Peripheral Arterial Disease (PAD). Since inflammation is so important in how these diseases start, are diagnosed, and treated, being able to see it…
- Trial name
- NCT06957821
- Testing
- Pegulicianine
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Massachusetts General Hospital
Moyamoya Disease, Moyamoya
Imaging in Moyamoya Disease - Study to Investigate Different Imaging Technologies for a Better Understanding of Various Imaging Techniques to Evaluate Cerebral Hemodynamics, Disease-activity and Possibly the Etiology in Moyamoya Patients
Aim of this study is to improve patient care in Moyamoya Patients by improving Imaging technologies and aiming to identify factors involved in disease progression.
- Trial name
- IMAGINE (NCT06330818)
- Testing
- MRI, H2 15O PET/CT, Biosampling
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Coronary Disease, Heart Diseases
VA HDL Intervention Trial (VA-HIT) Ancillary Study Data Analysis
To evaluate additional cardiovascular risk factors using data from the VA HDL Intervention Trial (VA-HIT).
- Conditions
- Coronary Disease, Heart Diseases, Cardiovascular Diseases, Carotid Artery Diseases
- Trial name
- NCT00035711
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Central Venous Catheterization, Surgery
Contralateral Head Rotation on Internal Jugular Vein to Carotid Artery Distance and Overlap Ratio
This study aims to find out the effect of contra lateral head rotation to distance and overlapping of internal jugular vein and carotid artery at cricoid cartilage level by ultrasound guidance on the Malay race in Indonesia
- Trial name
- NCT03741946
- Testing
- Triangle of Sedillot identification using ultrasonography
- Where
- Indonesia
- Volunteers
- 34 people
- Sponsor
- Universitas Indonesia
Carotid Artery Diseases
A Multicenter Study of Ultrafast Pulse Wave Velocity in Obese Chinese Han Adults
Ultrafast pulse wave velocity (UFPWV) is a novel non-invasive method developed recently to evaluate pulse wave velocity (PWV). This multi-center clinical trial aims to evaluate the feasibility of UFPWV in the evaluation of the…
- Trial name
- NCT05455099
- Testing
- Carotid ultrasound examination 1, Carotid ultrasound examination 2
- Where
- 22 sites in China
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- First Hospital of China Medical University
Identify the Presence of a Marker of Ischemia/Hypoperfusion of the Brain Via Peripheral Blood, Ischemia/Hypoperfusion of Brain
Biomarkers of Ischemia: Xanthine, Hypoxanthine and Inosine Levels During Carotid Stenting Procedures
The purpose of the study is to determine if a new blood test can help the doctor determine if there is brain injury or ischemia. Ischemia occurs when not enough oxygen gets to the brain.
- Trial name
- NCT01639534
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Virginia Commonwealth University
MPS I, MPS IV A
Cardiac Structure and Function in MPS
The purpose of this study is to better understand how heart and blood vessel problems develop in people with Mucopolysaccharidosis (MPS).
- Conditions
- MPS I, MPS IV A, MPS - Mucopolysaccharidosis, MPS IVA
- Trial name
- NCT07361536
- Where
- 3 sites in United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Orange County
Carotid Stenosis
Lifestyle Modification Programme for Patients With Asymptomatic Carotid Artery Stenosis
This study randomises patients with patients with asymptomatic carotid artery stenosis, to be managed either by providing an intensive 12-week lifestyle modification programme, or standard healthcare.
- Trial name
- NCT03929354
- Testing
- Risk Factors Modification Programme, Standard Care
- Where
- Ireland
- Volunteers
- 208 people
- Sponsor
- Western Vascular Institute, Ireland
Hypotension on Induction
Effect of Carotid Ultrasound-guided Fluid Management on Anesthetic-induced Hypotension in Elderly Patients Undergoing Gastrointestinal Surgery
The goal of this clinical trial is to learn about Whether carotid ultrasound guided fluid management can reduce the incidence of hypotension after general anesthesia induction in elderly patients undergoing gastrointestinal…
- Trial name
- NCT05891951
- Testing
- Fluid therapy under the guide of Carotid ultrasound
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Min Su
Coronary Artery Disease
Effect of Garlic Tablet Some Indicators Related to Atherosclerosis
The purpose of this study is to determine whether garlic in adjunct to conventional medical treatment is effective in improving carotid intima media thickness (CIMT), Flow mediated dilation (FMD) and plasma lipid profile or…
- Trial name
- NCT01948453
- Testing
- Garlic
- Where
- Iran
- Volunteers
- 56 people
- Sponsor
- Shahid Beheshti University
Atherosclerosis, Coronary Arteriosclerosis
Genetic- and Biological-Markers of Predisposition to Atherosclerosis: Leipzig-Heart Study
Atherosclerotic cardiovascular disease is the major cause of morbidity and mortality in Western societies. It is a complex genetic disorder with many genes involved and significant gene-environment interactions.
- Conditions
- Atherosclerosis, Coronary Arteriosclerosis, Carotid Artery Diseases, Genetic Predisposition to Disease
- Trial name
- LE-Heart (NCT00497887)
- Where
- 2 sites in Germany
- Volunteers
- 4,000 people
- Sponsor
- University of Leipzig
Stroke (CVA) or TIA, Headache, Migraine
Onabotulinum Toxin A (Botox) for the Treatment of Persistent Post-Stroke and Vascular Headache
Post stroke headache occurs in approximately 10-23% of all stroke patients. Its onset is shortly after experiencing a stroke, or stroke like event, and persists for at least three months.
- Conditions
- Stroke (CVA) or TIA, Headache, Migraine, Botulinum Toxins, Type A, Cerebral Venous Sinus Thrombosis
- Trial name
- NCT04580238
- Testing
- Botox 200 UNT Injection, Non Botox based Standard of Care Treatments for Headache/Migraine
- Where
- Canada
- Sponsor
- University of Alberta
Hyperlipidemias, Atherosclerosis
Percentage of Secondary Prevention Patients Treated to Their LDL-C Targets
A cholesterol/lipid profile screening project of high risk patients with hyperlipidaemia (secondary prevention) who already receive cholesterol-lowering therapy.
- Conditions
- Hyperlipidemias, Atherosclerosis, Coronary Heart Disease, Carotid Stenosis
- Trial name
- NCT00536965
- Where
- Austria
- Volunteers
- 951 people
- Sponsor
- AstraZeneca
Moyamoya Disease, Remote Ischemic Preconditioning
Effects of Remote Ischemic Preconditioning With Postconditioning on Neurologic Outcome
In the present study, we evaluated whether RIPC with RIPostC reduce the major neurocomplication in patients undergoing STA-MCA anastomosis.
- Trial name
- NCT03072914
- Testing
- RIPC with RIPostC
- Where
- South Korea
- Volunteers
- 108 people
- Sponsor
- Seoul National University Hospital
Ultrasonography, Carotid Stenosis
Prognostic Value of Carotid CEUS in Acute Ischemic Stroke Patients
Contrast-enhanced ultrasound(CEUS) of carotid artery plaque is a novel method that enabled direct visualization of neovessels in the vulnerable plaque.
- Conditions
- Ultrasonography, Carotid Stenosis, Ischemic Stroke
- Trial name
- NCT03283306
- Where
- South Korea
- Volunteers
- 667 people
- Sponsor
- Seoul National University Hospital
Cardiac Surgical Procedures
Diagnostic Accuracy of Doppler Resistive Indices for Early Diagnosis of Acute Kidney Injury .
To determine if ultrasound measurement of renal and carotid arterial resistive indices are associated with post-cardiac surgery acute kidney injury.
- Trial name
- NCT02580292
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Michigan
Homozygous Familial Hypercholesterolemia
Effects of Lomitapide on Carotid and Aortic Atherosclerosis
Study to assess changes in carotid and aortic atherosclerosis in patients being treated with lomitapide.
- Trial name
- NCT02399852
- Testing
- Lomitapide
- Sponsor
- Aegerion Pharmaceuticals, Inc.
Carotid Atherosclerotic Plaque
Prospective Management of Plaque Instability With Statins and Extra Folic Acid
This is a prospective, exploratory, cohort clinical study aiming to further investigate the direct impact of folic acid on the stability of carotid atherosclerotic plaques, building upon substantial clinical evidence confirming…
- Trial name
- PROMISE (NCT07680595)
- Testing
- Atorvastatin plus folic acid, Atorvastatin
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Ruijin Hospital
Aneurysms, Arteriovenous Malformations
Neurosurgical Outcome Network
The evaluation of neurosurgical outcomes varies from center to center, and the predictive factors that determine these outcomes are not fully known or shared.
- Conditions
- Aneurysms, Arteriovenous Malformations, Cavernomas, Skull Base Tumors
- Trial name
- NEON (NCT06724029)
- Where
- 27 sites in Italy
- Volunteers
- 4,500 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta