Clinical trials: Carotid Artery, open to volunteers
Internal Jugular Vein Anatomy, Common Carotid Artery Anatomy
Ultrasound Mapping of the Anatomical Relationship Between the Right Internal Jugular Vein and Carotid Artery
This prospective observational study will describe the anatomical relationship between two major blood vessels on the right side of the neck: the internal jugular vein and the common carotid artery.
- Conditions
- Internal Jugular Vein Anatomy, Common Carotid Artery Anatomy, Cardiac Surgery
- Trial name
- IJVCCA (NCT07893080)
- Testing
- Standardized Ultrasound Imaging and Computer-Assisted Angular Mapping
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Ankara City Hospital Bilkent
Extracranial Carotid Artery Disease, TCAR
Real-World Treatment of Extracranial Carotid Artery Disease With the ENROUTE™ Transcarotid Neuroprotection System
The ENTRUST registry's objective is to collect real-world data (RWD) and health economic data on the ENROUTE™ Transcarotid Neuroprotection System (ENROUTE™ Transcarotid NPS), including populations in which outcomes of…
- Conditions
- Extracranial Carotid Artery Disease, TCAR, Transcarotid Artery Revascularization
- Trial name
- ENTRUST (NCT07455747)
- Testing
- Use of ENROUTE™ Transcarotid Neuroprotection System in conjunction with any commercially available Boston Scientific stent marketed for treatment of carotid artery disease
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Boston Scientific Corporation
Internal Carotid Artery Dolichoarteriopathy, Carotid Artery Tortuosity
Clinical Significance of Internal Carotid Artery Dolichoarteriopathy
This observational study aims to investigate the clinical significance of internal carotid artery dolichoarteriopathy, including tortuosity, kinking, and coiling, and to identify factors associated with cerebral dysfunction and…
- Trial name
- DALISTA (NCT07882875)
- Where
- Russia
- Volunteers
- 560 people
- Sponsor
- Kuban State Medical University
Carotid Artery, Carotid Arteriosclerosis
Predicting High-Risk Carotid Plaque: Integrating radioMics and biomEchanics
Non-pharmacological interventional study for the development of a predictive model aimed at identifying unstable carotid plaques in asymptomatic patients at first diagnosis, with the use of biological material and…
- Trial name
- PRIME (NCT07877480)
- Testing
- Radiomic features analysis
- Where
- Italy
- Volunteers
- 420 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Carotid Artery Calcification, Carotid Artery Diseases
Study of the Shockwave Medical SkyRunner Carotid Intravascular Lithotripsy (IVL) System for the Treatment of Calcified Carotid Arteries Prior to Trans-Carotid Stenting (SKYWARD Trans-Carotid IDE [Investigational Device Exemption] Study)
Prospective, Multi-center, Single-arm Study of the Shockwave Medical SkyRunner Carotid Intravascular Lithotripsy (IVL) System for the Treatment of Calcified Carotid Arteries prior to Trans-Carotid Stenting (SKYWARD Trans-Carotid…
- Trial name
- NCT07062471
- Testing
- Carotid Intravascular Lithotripsy (IVL)
- Where
- 25 sites in United States
- Volunteers
- 185 people
- Sponsor
- Shockwave Medical, Inc.
Transradial Carotid Artery Stenting, Novel Composite-tip Guiding Catheter
Safety and Efficacy of a Novel Composite-Tip Guiding Catheter in Transcarotid Artery Stenting Via Transradial Access
This study aims to evaluate the safety and efficacy of the novel composite-tip guiding catheter for transradial access in Carotid Artery Stenting procedures
- Trial name
- NCT07377422
- Testing
- Composite-Tip Transradial Neurovascular Distal Access Catheter, Straight or Single-Curve Tip Guiding Catheter
- Where
- China
- Volunteers
- 204 people
- Sponsor
- Beijing Anzhen Hospital
Carotid Artery Stenosis
A Prospective, Multicenter, Single Arm Registry of ENROUTE NPS in Conjunction With Carotid WALLSTENT in Chinese Population
The study is a prospective, non-randomized, single-arm, multi-center registry to confirm the safe delivery of the Carotid WALLSTENT Endoprosthesis when used with the ENROUTE® Transcarotid Neuroprotection System in the Chinese…
- Trial name
- ASCENT-C (NCT07458243)
- Testing
- transcarotid artery revascularization
- Volunteers
- 60 people
- Sponsor
- Boston Scientific Corporation
Internal Carotid Artery Stenosis
Safety and Efficacy of Carotid Artery Stenting Combined With Intermittent Hypoxia Intervention in Patients With Severe Internal Carotid Artery Stenosis
This study aims to explore the efficacy of Intermittent Hypoxia Treatment (IHT) in preventing peri-operative embolism-related microinfarcts among patients with severe internal carotid artery stenosis (ICAS) undergoing carotid…
- Trial name
- NCT07837011
- Testing
- intermittent hypoxia intervention, Carotid Artery Stenting (CAS), Standard Medical Therapy
- Where
- China
- Volunteers
- 176 people
- Sponsor
- Capital Medical University
Carotid Artery Plaques, Atherosclerosis
Effects of Rosa Roxburghii Tratt Freeze-Dried Powder on Carotid Atherosclerotic Plaques: A Real-World Study
This study aims to evaluate the effectiveness and safety of Rosa roxburghii freeze-dried powder in reducing carotid atherosclerotic plaques.
- Conditions
- Carotid Artery Plaques, Atherosclerosis, Ischemic Stroke
- Trial name
- RRC-AS (NCT07840950)
- Testing
- Rosa Roxburghii Freeze-Dried Powder, Conventional Anti-Atherosclerosis Therapy
- Volunteers
- 200 people
- Sponsor
- Xiangya Hospital of Central South University
Carotid Artery Stenosis (Symptomatic and Asymptomatic)
CEST-PROTECT: Proximal Flow Control With a Balloon Guide Catheter Plus Distal Embolic Protection: a Randomised, Open-label Trial Evaluating Cerebral Protection Techniques
This randomized controlled trial aims to evaluate whether a proximal-distal dual cerebral protection strategy can reduce the occurrence of new cerebral ischemic lesions compared with a single cerebral protection strategy in…
- Trial name
- CEST-PROTECT (NCT07841132)
- Testing
- BGC proximal flow control plus distal filter embolic protection device during carotid artery stenting, Single distal filter embolic protection device during carotid artery stenting
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Xuanwu Hospital, Beijing
Aorta Aneurysm, Carotid Arteriosclerosis
The Role Oral Microbiome in the Development and Progression of Aorta Aneurysm and Carotid Atherosclerosis
The goal of this observational study is to compare the microbiome (bacterial al community) of the diseased vascular site and the oral cavity with specific attention to chronic inflammatory periodontitis in patients who have aorta…
- Trial name
- OMB (NCT07824921)
- Where
- Hungary
- Volunteers
- 100 people
- Sponsor
- Semmelweis University
Carotid Artery Diseases, Aortic Diseases
Intervascular Post-Market Clinical Follow-Up (PMCF) Registry
The purpose of this registry is to evaluate the long-term safety and performance of Intervascular Vascular Grafts and Patches (Intergard Standard, Hemashield, Intergard Silver, Intergard Synergy) for bypass, repair or replacement…
- Conditions
- Carotid Artery Diseases, Aortic Diseases, Peripheral Arterial Diseases
- Trial name
- NCT07322913
- Testing
- Intergard Standard - Collagen Coated Vascular Grafts and Patches, Hemashield - Collagen Coated Vascular Grafts and Patches, Intergard Silver - Antimicrobial Collagen Coated Vascular Grafts and Patches
- Where
- 5 sites in United States, Belgium and 2 more
- Volunteers
- 1,200 people
- Sponsor
- Intervascular
Carotid Stenosis, Carotid Artery Diseases
Cerebral Oximetry During Awake Carotid Endarterectomy
Surgery to remove plaque from the carotid artery in the neck requires the artery to be clamped for a period of time. In some patients this reduces blood flow to the brain enough to cause temporary symptoms, and a temporary…
- Conditions
- Carotid Stenosis, Carotid Artery Diseases, Brain Ischemia, Carotid Endarterectomy
- Trial name
- COACE (NCT07816081)
- Testing
- Masked continuous cerebral oximetry, Standardised awake neurological test, Serial cognitive assessment
- Where
- Vietnam
- Volunteers
- 150 people
- Sponsor
- Nguyen Toan Thang
Non-acute Carotid Artery Occlusion, Cognitive Impairment
Endovascular Treatment for Symptomatic Non-acute Carotid Occlusion
This study is a multicenter, prospective, randomized, open-label, blinded-endpoint clinical trial designed to evaluate the safety and potential efficacy of endovascular recanalization strategies in patients with symptomatic…
- Trial name
- ASCENT (NCT07803419)
- Testing
- Guideline-Based Best Medical Treatment, Endovascular Recanalization With Proximal Balloon Protection, Endovascular Recanalization Without Proximal Protection
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Dapeng Mo
Carotid Artery Stenosis
Balloon Guide Catheter Combined With Filter Protection for Carotid Artery Stenting
This multicenter, randomized, controlled trial evaluates a combined embolic protection strategy during carotid artery stenting (CAS). Carotid artery stenosis is a major cause of stroke.
- Trial name
- ANGEL-BEACON (NCT07247864)
- Testing
- Balloon Guide Catheter, Distal Filter Protection Device
- Where
- China
- Volunteers
- 296 people
- Sponsor
- Beijing Anzhen Hospital
Aneurysm, Dissection
PANTHER Study of Terumo Aortic Knitted and Woven Grafts, and Cardiovascular Patches
The purpose of this registry is to collect safety and performance data on all commercially available Terumo Aortic knitted and woven grafts, and cardiovascular patches in standard clinical practice.
- Conditions
- Aneurysm, Dissection, Aortic Root Aneurysm, Aortic Root Dissection
- Trial name
- PANTHER (NCT04545502)
- Testing
- Gelsoft Plus Vascular Graft, Vascular Bypass Graft, Cardiovascular Patch
- Where
- 30 sites in United States, Belgium and 4 more
- Volunteers
- 2,000 people
- Sponsor
- Vascutek Ltd.
Carotid Artery Stenosis, Carotid Atherosclerosis
Photon-Counting CT Versus Conventional CT for Carotid Plaque Assessment in Patients With Carotid Artery Stenosis
This prospective observational study aims to compare photon-counting detector computed tomography angiography (PCD-CTA) with conventional energy-integrating detector computed tomography angiography (EID-CTA) for the assessment of…
- Conditions
- Carotid Artery Stenosis, Carotid Atherosclerosis, Carotid Atherosclerotic Plaque
- Trial name
- NCT07762664
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Chinese PLA General Hospital
Stroke, Acute, Carotid Stenosis
Endovascular Acute Stroke Intervention - Tandem OCclusion Trial
Patients with tandem occlusion or tandem lesion (TL), that is, stroke with an acute intracranial anterior circulation occlusion and an ipsilateral cervical ICA (c-ICA) high-grade stenosis or occlusion, constitute about 15-20% of…
- Conditions
- Stroke, Acute, Carotid Stenosis, Carotid Artery Diseases
- Trial name
- EASI-TOC (NCT04261478)
- Testing
- Carotid artery stenting, Antiplatelet Agents
- Where
- Canada
- Volunteers
- 458 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Ischemic Stroke, Transient Ischemic Attack
Comparison Between Non-contrast Magnetic Resonance Angiography and Carotid Doppler in Cerebrovascular Stroke
This prospective observational study aims to compare the diagnostic performance of non-contrast magnetic resonance angiography (NC-MRA) and carotid Doppler ultrasonography in the evaluation of carotid artery disease among…
- Conditions
- Ischemic Stroke, Transient Ischemic Attack, Carotid Artery Stenosis (Symptomatic and Asymptomatic)
- Trial name
- NCT07756775
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Sohag University
Carotid Artery Stenosis
A Cohort Study Comparing PCSK9 Inhibitor Plus Statin With Statin Monotherapy for Carotid Artery Stenosis
A multicenter cohort study
- Trial name
- TRIP-CAS (NCT07036991)
- Testing
- PCSK9 inhibitor (biweekly injections) + Rosuvastatin/Atorvastatin ± Ezetimibe, Rosuvastatin/Atorvastatin ± Ezetimibe
- Where
- China
- Volunteers
- 406 people
- Sponsor
- Changhai Hospital